Home Carboxes 4027-59-2
4027-59-2,MFCD06742804
Catalog No.:AA0073NN

4027-59-2 | 5-Ethyl-1h-pyrazole-3-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$132.00   $92.00
- +
250mg
95%
in stock  
$185.00   $130.00
- +
1g
95%
in stock  
$594.00   $416.00
- +
5g
95%
in stock  
$1,924.00   $1,347.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0073NN
Chemical Name:
5-Ethyl-1h-pyrazole-3-carboxylic acid
CAS Number:
4027-59-2
Molecular Formula:
C6H8N2O2
Molecular Weight:
140.1399
MDL Number:
MFCD06742804
SMILES:
CCc1[nH]nc(c1)C(=O)O
Properties
Computed Properties
 
Complexity:
138  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
0.9  

Downstream Synthesis Route

[1]Skinner,PhilipJ.;Cherrier,MartinC.;Webb,PeterJ.;Shin,Young-Jun;Gharbaoui,Tawfik;Lindstrom,Andrew;Hong,Vu;Tamura,SusanY.;Dang,HuongT.;Pride,CameronC.;Chen,Ruoping;Richman,JeremyG.;Connolly,DanielT.;Semple,Graeme[BioorganicandMedicinalChemistryLetters,2007,vol.17,#20,p.5620-5623]

[1]Locationinpatent:experimentalpartYan,Lin;Huo,Pei;Debenham,JohnS.;Madsen-Duggan,ChristinaB.;Lao,Julie;Chen,RichardZ.;Xiao,JingChen;Shen,Chun-Pyn;Stribling,D.Sloan;Shearman,LaurenP.;Strack,AlisonM.;Tsou,Nancy;Ball,RichardG.;Wang,Junying;Tong,Xinchun;Bateman,ThomasJ.;Reddy,VijayB.G.;Fong,TungM.;Hale,JeffreyJ.[JournalofMedicinalChemistry,2010,vol.53,#10,p.4028-4037]

Literature

Title: Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.

Journal: Bioorganic & medicinal chemistry letters 20071015

Title: Agonist lead identification for the high affinity niacin receptor GPR109a.

Journal: Bioorganic & medicinal chemistry letters 20070901

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:4027-59-2 Molecular Formula|4027-59-2 MDL|4027-59-2 SMILES|4027-59-2 5-Ethyl-1h-pyrazole-3-carboxylic acid