Home Other Building Blocks 40505-27-9
40505-27-9,MFCD01725607
Catalog No.:AA003AP2

40505-27-9 | 4'-Demethylpodophyllotoxin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$41.00   $29.00
- +
5mg
≥98%
in stock  
$62.00   $43.00
- +
10mg
97%
in stock  
$87.00   $61.00
- +
25mg
97%
in stock  
$214.00   $150.00
- +
50mg
97%
in stock  
$310.00   $217.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003AP2
Chemical Name:
4'-Demethylpodophyllotoxin
CAS Number:
40505-27-9
Molecular Formula:
C21H20O8
Molecular Weight:
400.3787
MDL Number:
MFCD01725607
SMILES:
COc1cc(cc(c1O)OC)[C@H]1[C@H]2C(=O)OC[C@@H]2[C@H](c2c1cc1OCOc1c2)O
Properties
Computed Properties
 
Complexity:
614  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
1.7  

Literature

Title: Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi.

Journal: Bioorganic & medicinal chemistry letters 20110615

Title: Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell lines.

Journal: Journal of natural products 20070201

Title: (-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase.

Journal: Journal of medicinal chemistry 19960105

Title: David E.Jackson, et al. Aryltetralin lignans from Podophyllum hexandrum and Podophyllum peltatum. Phytochemistry, 1984, 23(5): 1147-1152.

Title: Zilla MK, et al. 4'-Demethyl-deoxypodophyllotoxin glucoside isolated from Podophyllum hexandrum exhibits potential anticancer activities by altering Chk-2 signaling pathway in MCF-7 breast cancer cells. Chem Biol Interact. 2014 Dec 5;224:100-7.

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SDS
Tags:40505-27-9 Molecular Formula|40505-27-9 MDL|40505-27-9 SMILES|40505-27-9 4'-Demethylpodophyllotoxin