Home Other Building Blocks 407587-33-1
407587-33-1,MFCD02919058
Catalog No.:AA00CHTI

407587-33-1 | Caccinh-a01

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$25.00   $18.00
- +
5mg
98%
in stock  
$89.00   $62.00
- +
10mg
98%
in stock  
$149.00   $104.00
- +
25mg
98%
in stock  
$252.00   $177.00
- +
500mg
98% by HPLC
in stock  
$3,439.00   $2,407.00
- +
1000mg
98% by HPLC
in stock  
$5,464.00   $3,825.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00CHTI
Chemical Name:
Caccinh-a01
CAS Number:
407587-33-1
Molecular Formula:
C18H21NO4S
Molecular Weight:
347.4286
MDL Number:
MFCD02919058
SMILES:
OC(=O)c1c(sc2c1CCC(C2)C(C)(C)C)NC(=O)c1ccco1
Properties
Computed Properties
 
Complexity:
504  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
5.1  

Upstream Synthesis Route

[1]Patent:US9789095,2017,B2,.Locationinpatent:Page/Pagecolumn8;60

[2]MolecularPharmacology,2008,vol.73,#3,p.758-768

[1]Patent:US9789095,2017,B2,

[1]Patent:US9789095,2017,B2,

Literature

Title: Pyrophosphatase and glucuronosyltransferase in microsomal UDPglucuronic-acid metabolism in the rat liver.

Journal: European journal of biochemistry 19760102

Title: TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloridechannel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21;286(3):2365-74.

Title: De La Fuente R, et al. Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloridechannel. Mol Pharmacol. 2008 Mar;73(3):758-68.

Title: Pin-Yi Liu, et al. TMEM16A Inhibition Preserves Blood-Brain Barrier Integrity After Ischemic Stroke.Front Cell Neurosci. 2019 Aug 6;13:360.

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SDS
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