Home Carboxes 408309-29-5
408309-29-5,MFCD08234482
Catalog No.:AA00CIO0

408309-29-5 | 3-(1H-Pyrrol-2-yl)propanoic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$43.00   $30.00
- +
250mg
95%
in stock  
$81.00   $57.00
- +
500mg
95%
in stock  
$144.00   $101.00
- +
1g
95%
in stock  
$203.00   $142.00
- +
10g
95%
in stock  
$1,974.00   $1,382.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00CIO0
Chemical Name:
3-(1H-Pyrrol-2-yl)propanoic acid
CAS Number:
408309-29-5
Molecular Formula:
C7H9NO2
Molecular Weight:
139.1519
MDL Number:
MFCD08234482
SMILES:
OC(=O)CCc1ccc[nH]1
Properties
Properties
 
Form:
Solid  
MP:
85-86℃  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
125  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
0.6  

Upstream Synthesis Route

[1]Patent:US5512603,1996,A,

[1]Patent:WO2009/139834,2009,A1,.Locationinpatent:Page/Pagecolumn161

[2]EuropeanJournalofOrganicChemistry,2010,#19,p.3611-3620

[3]Tetrahedron,2004,vol.60,#7,p.1505-1511

[1]OrganicandBiomolecularChemistry,2018,vol.16,#12,p.2125-2133

[1]Tetrahedron,2004,vol.60,#7,p.1505-1511

[1]Patent:US5512603,1996,A,

Downstream Synthesis Route

[1]Hoppe-Seyler'sZeitschriftfurPhysiologischeChemie,1952,vol.289,p.229,231

[1]JournaloftheChemicalSociety,1952,p.2433

[1]Hoppe-Seyler'sZeitschriftfurPhysiologischeChemie,1952,vol.289,p.229,231

[1]Tetrahedron,2004,vol.60,p.1505-1511

[1]Patent:WO2009/139834,2009,A1.Locationinpatent:Page/Pagecolumn161

[2]EuropeanJournalofOrganicChemistry,2010,p.3611-3620

[3]Tetrahedron,2004,vol.60,p.1505-1511

Literature

Title: How does the macula protect itself from oxidative stress?

Journal: Molecular aspects of medicine 20120801

Title: The past, present, and future of exudative age-related macular degeneration treatment.

Journal: Middle East African journal of ophthalmology 20120101

Title: Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks.

Journal: Genome medicine 20120101

Title: The significance of the complement system for the pathogenesis of age-related macular degeneration - current evidence and translation into clinical application.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110201

Title: Age-related retinopathy in NRF2-deficient mice.

Journal: PloS one 20110101

Title: Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration.

Journal: Journal of translational medicine 20110101

Title: Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes.

Journal: Molecular & cellular proteomics : MCP 20100601

Title: A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.

Journal: Molecular neurobiology 20100601

Title: Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).

Journal: Progress in retinal and eye research 20100501

Title: Proteomic and genomic biomarkers for age-related macular degeneration.

Journal: Advances in experimental medicine and biology 20100101

Title: Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration.

Journal: Bioorganic & medicinal chemistry 20091101

Title: Supranormal electroretinogram in fat-1 mice with retinas enriched in docosahexaenoic acid and n-3 very long chain fatty acids (C24-C36).

Journal: Investigative ophthalmology & visual science 20090901

Title: Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.

Journal: Molecular & cellular proteomics : MCP 20090801

Title: Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.

Journal: Molecular & cellular proteomics : MCP 20090601

Title: Retinal pigment epithelium lipofuscin proteomics.

Journal: Molecular & cellular proteomics : MCP 20080701

Title: Oxidative damage-induced inflammation initiates age-related macular degeneration.

Journal: Nature medicine 20080201

Title: Carboxyethylpyrrole adducts, age-related macular degeneration and neovascularization.

Journal: Advances in experimental medicine and biology 20080101

Title: Age-related macular degeneration: a target for nanotechnology derived medicines.

Journal: International journal of nanomedicine 20070301

Title: The future implications and indications of anti-vascular endothelial growth factor therapy in ophthalmic practice.

Journal: Indian journal of ophthalmology 20070101

Title: Protective effects of soft acrylic yellow filter against blue light-induced retinal damage in rats.

Journal: Experimental eye research 20061201

Title: Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

Journal: The Journal of biological chemistry 20031024

Title: Oxidatively truncated docosahexaenoate phospholipids: total synthesis, generation, and Peptide adduction chemistry.

Journal: The Journal of organic chemistry 20030516

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:408309-29-5 Molecular Formula|408309-29-5 MDL|408309-29-5 SMILES|408309-29-5 3-(1H-Pyrrol-2-yl)propanoic acid