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41552-82-3,MFCD00036845
Catalog No.:AA00C090

41552-82-3 | N6-CYCLOPENTYLADENOSINE

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Purity
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10mg
≥98%
in stock  
$46.00   $32.00
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50mg
≥98%
in stock  
$166.00   $116.00
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100mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00C090
Chemical Name:
N6-CYCLOPENTYLADENOSINE
CAS Number:
41552-82-3
Molecular Formula:
C15H21N5O4
Molecular Weight:
335.3583
MDL Number:
MFCD00036845
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1
Properties
Properties
 
BP:
673.4°C at 760 mmHg  
Form:
Solid  
MP:
78.8℃  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
438  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
0.9  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,2000,vol.43,p.250-260

Literature

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Title: Activation of NTS A(1) adenosine receptors inhibits regional sympathetic responses evoked by activation of cardiopulmonary chemoreflex.

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Title: Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.

Journal: Journal of medicinal chemistry 20120726

Title: Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120715

Title: The effects of A1 and A2A adenosine receptor agonists on kainic acid excitotoxicity in the guinea pig cochlea.

Journal: Neuroscience letters 20120614

Title: Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120601

Title: Pharmacological characterization of adenosine receptors on isolated human bronchi.

Journal: American journal of respiratory cell and molecular biology 20111201

Title: Activation of adenosine A1 receptor attenuates tumor necrosis factor-α induced hypertrophy of cardiomyocytes.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20111001

Title: [Proteomics analysis of adenosine A1 receptor agonist-induced delayed myocardial protection in rabbits].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20111001

Title: Expression of human equilibrative nucleoside transporter 1 in mouse neurons regulates adenosine levels in physiological and hypoxic-ischemic conditions.

Journal: Journal of neurochemistry 20110701

Title: Role of large-conductance Ca²+-activated K+ channels in adenosine A₁ receptor-mediated pharmacological postconditioning in H9c2 cells.

Journal: Canadian journal of physiology and pharmacology 20110101

Title: A1 receptors self-regulate adenosine release in the striatum: evidence of autoreceptor characteristics.

Journal: Neuroscience 20101229

Title: Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats.

Journal: Brain research 20101118

Title: Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.

Journal: Journal of cardiovascular pharmacology 20101001

Title: A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate.

Journal: Journal of cardiovascular pharmacology 20100901

Title: Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemia-reperfusion injury.

Journal: The Journal of thoracic and cardiovascular surgery 20100801

Title: Adenosine A(3) receptor stimulation induces protection of skeletal muscle from eccentric exercise-mediated injury.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100701

Title: Indirect basal ganglia pathway mediation of repetitive behavior: attenuation by adenosine receptor agonists.

Journal: Behavioural brain research 20100626

Title: P2X(1) receptor blockade inhibits whole kidney autoregulation of renal blood flow in vivo.

Journal: American journal of physiology. Renal physiology 20100601

Title: A1 receptor mediated adenosinergic regulation of perifornical-lateral hypothalamic area neurons in freely behaving rats.

Journal: Neuroscience 20100428

Title: 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20100315

Title: Adenosine A1 receptor activation reduces opening of mitochondrial permeability transition pores in hypoxic cardiomyocytes.

Journal: Clinical and experimental pharmacology & physiology 20100301

Title: Compensatory upregulation of the adenosine system following phenylephrine-induced hypertrophy in cultured rat ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20100201

Title: Role of adenosine A(1) receptor in the perifornical-lateral hypothalamic area in sleep-wake regulation in rats.

Journal: Brain research 20091222

Title: The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues.

Journal: Neurochemistry international 20091201

Title: Fabrication via a nonaqueous nanoprecipitation method, characterization and in vitro biological behavior of N(6)-cyclopentyladenosine-loaded nanoparticles.

Journal: Journal of pharmaceutical sciences 20091101

Title: Vasopressin is a major vasoconstrictor involved in hindlimb vascular responses to stimulation of adenosine A(1) receptors in the nucleus of the solitary tract.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Role of large-conductance Ca(2+) -activated potassium channels in adenosine A(1) receptor-mediated pharmacological preconditioning in H9c2 cells.

Journal: European journal of pharmacology 20090915

Title: Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons.

Journal: Brain research 20090714

Title: Adenosine A(1) receptor-mediated transactivation of the EGF receptor produces a neuroprotective effect on cortical neurons in vitro.

Journal: Acta pharmacologica Sinica 20090701

Title: Regulation of somatostatin release by adenosine in the mouse stomach.

Journal: The Journal of pharmacology and experimental therapeutics 20090501

Title: Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.

Journal: Journal of cardiovascular pharmacology 20090501

Title: Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.

Journal: Current drug safety 20090501

Title: N6-Cycloalkyl- and N6-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A1 adenosine receptor with antinociceptive effects in mice.

Journal: Journal of medicinal chemistry 20090423

Title: Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA.

Journal: Basic research in cardiology 20090301

Title: Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.

Journal: European journal of pharmacology 20090114

Title: The effects of systemic, intrastriatal, and intrapallidal injections of caffeine and systemic injections of A2A and A1 antagonists on forepaw stepping in the unilateral 6-OHDA-lesioned rat.

Journal: Psychopharmacology 20090101

Title: Brainstem adenosine A1 receptor signaling masks phosphorylated extracellular signal-regulated kinase 1/2-dependent hypotensive action of clonidine in conscious normotensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20090101

Title: [Effect of cyclopentyladenosine on the orientation, exploratory, and emotional behavior of rats with model brain injury].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20090101

Title: [Importance of selective A1 agonists for the protection of brain and heart against injuring factors].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20090101

Title: Adenosine modulates alpha2-adrenergic receptors within specific subnuclei of the nucleus tractus solitarius in normotensive and spontaneously hypertensive rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20081201

Title: The potential role of the nodose ganglion adenosine A1 receptor in regulation of breathing in anaesthetized rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201

Title: Brain uptake of an anti-ischemic agent by nasal administration of microparticles.

Journal: Journal of pharmaceutical sciences 20081101

Title: Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones.

Journal: Pflugers Archiv : European journal of physiology 20081101

Title: Synthesis of bivalent beta2-adrenergic and adenosine A1 receptor ligands.

Journal: Journal of medicinal chemistry 20081009

Title: 2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20080814

Title: Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.

Journal: Journal of medicinal chemistry 20080724

Title: Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080701

Title: Homeostatic action of adenosine A3 and A1 receptor agonists on proliferation of hematopoietic precursor cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20080701

Title: Adenosine receptor agonists attenuate the development of diazepam withdrawal-induced sensitization in mice.

Journal: European journal of pharmacology 20080624

Title: Solid lipid microparticles for the stability enhancement of the polar drug N6-cyclopentyladenosine.

Journal: International journal of pharmaceutics 20080501

Title: Changes in the control of gastric motor activity during metamorphosis in the amphibian Xenopus laevis, with special emphasis on purinergic mechanisms.

Journal: The Journal of experimental biology 20080401

Title: A new generation of adenosine receptor antagonists: from di- to trisubstituted aminopyrimidines.

Journal: Bioorganic & medicinal chemistry 20080315

Title: Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons.

Journal: Experimental brain research 20080301

Title: Hypoxia induces cardiac malformations via A1 adenosine receptor activation in chicken embryos.

Journal: Birth defects research. Part A, Clinical and molecular teratology 20080301

Title: N6-substituted C5'-modified adenosines as A1 adenosine receptor agonists.

Journal: Bioorganic & medicinal chemistry 20080215

Title: Repetitive stimulation of adenosine A1 receptors in vivo: changes in receptor numbers, G-proteins and A1 receptor agonist-induced hypothermia.

Journal: Brain research 20080129

Title: A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals.

Journal: Neuroscience letters 20080117

Title: 5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species.

Journal: Bioorganic & medicinal chemistry 20080101

Title: Stimulation of NTS A1 adenosine receptors differentially resets baroreflex control of regional sympathetic outputs.

Journal: American journal of physiology. Heart and circulatory physiology 20080101

Title: Functional expression of the adenosine A1 receptor in rabbit lacrimal gland.

Journal: Experimental eye research 20080101

Title: Paradoxical effects of adenosine receptor ligands on hydroxyl radical generation by L-DOPA in the rat striatum.

Journal: Pharmacological reports : PR 20080101

Title: Effect of the pyridoindole SMe1EC2 and compounds affecting A(1) and A(2A) adenosine receptors in rat hippocampus under ischemia in vitro.

Journal: Pharmacological reports : PR 20080101

Title: Rhythm generation by the pre-Bötzinger complex in medullary slice and island preparations: effects of adenosine A(1) receptor activation.

Journal: BMC neuroscience 20080101

Title: Involvement of adenosine receptor agonists on the development of hypersensitivity to acute dose of morphine during morphine withdrawal period.

Journal: Pharmacological reports : PR 20080101

Title: Adenosine induces expression of glial cell line-derived neurotrophic factor (GDNF) in primary rat astrocytes.

Journal: Neuroscience research 20071201

Title: C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus.

Journal: Neuropharmacology 20071201

Title: Adenosine A1 receptor-mediated inhibition of dopamine release from rat striatal slices is modulated by D1 dopamine receptors.

Journal: The European journal of neuroscience 20071201

Title: Influence of adenosine A(1)-receptor blockade and vagotomy on the gasping and heart rate response to hypoxia in rats during early postnatal maturation.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20071001

Title: Dual acting antioxidant A1 adenosine receptor agonists.

Journal: Bioorganic & medicinal chemistry letters 20071001

Title: Stimulation of adenosine A1 receptors decreases in vivo dopamine D1 receptor binding of [11C]SCH23390 in the cat striatum revealed by positron emission tomography.

Journal: Annals of nuclear medicine 20071001

Title: Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium.

Journal: Pharmacological research 20070801

Title: Activation of the A1 adenosine receptor increases insulin-stimulated glucose transport in isolated rat soleus muscle.

Journal: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20070801

Title: Differential expression of cerebellar metabotropic glutamate receptors mGLUR2/3 and mGLUR4a after the administration of a convulsant drug and the adenosine analogue cyclopentyladenosine.

Journal: Neurochemical research 20070701

Title: ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate.

Journal: Clinical and experimental pharmacology & physiology 20070701

Title: Presynaptic modulation of 5-HT release in the rat septal region.

Journal: Neuroscience 20070511

Title: Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation.

Journal: Neuroscience letters 20070511

Title: The enhancement of dopamine D1 receptor desensitization by adenosine A1 receptor activation.

Journal: European journal of pharmacology 20070507

Title: Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats.

Journal: Psychopharmacology 20070301

Title: 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.

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Title: Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.

Journal: Neuropharmacology 20070201

Title: Correlations between acetylcholinesterase inhibition, acetylcholine levels and EEG changes during perfusion with neostigmine and N6-cyclopentyladenosine in rat brain.

Journal: European journal of pharmacology 20070126

Title: Interaction of valerian extracts of different polarity with adenosine receptors: identification of isovaltrate as an inverse agonist at A1 receptors.

Journal: Biochemical pharmacology 20070115

Title: Dipyridamole promotes changes in calbindin-D28k and tyrosine hydroxylase expression in neonatal rats.

Journal: Neonatology 20070101

Title: Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells.

Journal: European journal of pharmacology 20061024

Title: Activation of adenosine A1 receptors reduces anxiety-like behavior during acute ethanol withdrawal (hangover) in mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20061001

Title: Stimulation of adenosine receptors selectively activates gene expression in striatal enkephalinergic neurons.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20061001

Title: Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20061001

Title: Nitric oxide mediates interactions between GABAA receptors and adenosine A1 receptors in the rat hippocampus.

Journal: European journal of pharmacology 20060814

Title: The effect of an adenosine A1 receptor agonist in the treatment of experimental subarachnoid hemorrhage-induced cerebrovasospasm.

Journal: Acta neurochirurgica 20060801

Title: Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.

Journal: Kidney international 20060801

Title: Potentiation of adenosine A1 receptor agonist CPA-induced antinociception by paeoniflorin in mice.

Journal: Biological & pharmaceutical bulletin 20060801

Title: A novel role for protein phosphatase 2A in receptor-mediated regulation of the cardiac sarcolemmal Na+/H+ exchanger NHE1.

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Title: A novel approach for medical countermeasures to nerve agent poisoning in the guinea-pig.

Journal: Neurotoxicology 20060701

Title: The allosteric enhancer PD81,723 increases chimaeric A1/A2A adenosine receptor coupling with Gs.

Journal: The Biochemical journal 20060515

Title: Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway.

Journal: The Biochemical journal 20060515

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors.

Journal: Autonomic & autacoid pharmacology 20060401

Title: Presynaptic GABA(B) receptors on glutamatergic terminals of CA1 pyramidal cells decrease in efficacy after partial hippocampal kindling.

Journal: Synapse (New York, N.Y.) 20060301

Title: Allosteric modulation, thermodynamics and binding to wild-type and mutant (T277A) adenosine A1 receptors of LUF5831, a novel nonadenosine-like agonist.

Journal: British journal of pharmacology 20060301

Title: Adenosine receptors as therapeutic targets.

Journal: Nature reviews. Drug discovery 20060301

Title: The role of adenosine A2A and A3 receptors on the differential modulation of norepinephrine and neuropeptide Y release from peripheral sympathetic nerve terminals.

Journal: Journal of neurochemistry 20060301

Title: Activation of adenosine A(1) receptors alters behavioral and biochemical parameters in hyperthyroid rats.

Journal: Behavioural brain research 20060227

Title: Nanoparticle formulation may affect the stabilization of an antiischemic prodrug.

Journal: International journal of pharmaceutics 20060103

Title: Effect of nucleoside transport blockade on the interstitial adenosine level characterized by a novel method in guinea pig atria.

Journal: Journal of cardiovascular pharmacology 20060101

Title: Polymeric nanoparticles as drug controlled release systems: a new formulation strategy for drugs with small or large molecular weight.

Journal: Journal of nanoscience and nanotechnology 20060101

Title: Semi-rational design of (north)-methanocarba nucleosides as dual acting A(1) and A(3) adenosine receptor agonists: novel prototypes for cardioprotection.

Journal: Journal of medicinal chemistry 20051229

Title: A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors.

Journal: Psychopharmacology 20051201

Title: Adenosine-stimulated atrial natriuretic peptide release through A1 receptor subtype.

Journal: Hypertension (Dallas, Tex. : 1979) 20051201

Title: The antinociceptive effects of the systemic adenosine A1 receptor agonist CPA in the absence and in the presence of spinal cord sensitization.

Journal: Pharmacology, biochemistry, and behavior 20051201

Title: Effects of single and long-term theophylline treatment on the threshold of mechanical nociception: contribution of adenosine A1 and alpha2-adrenoceptors.

Journal: Methods and findings in experimental and clinical pharmacology 20051101

Title: Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice.

Journal: European journal of pharmacology 20051031

Title: Allosteric modulators affect the internalization of human adenosine A1 receptors.

Journal: European journal of pharmacology 20051017

Title: Different roles of adenosine A1, A2A and A3 receptors in controlling kainate-induced toxicity in cortical cultured neurons.

Journal: Neurochemistry international 20051001

Title: 2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.

Journal: European journal of pharmacology 20050822

Title: Enhancement of wind-up by the combined administration of adenosine A1 receptor ligands on spinalized rats with carrageenan-induced inflammation.

Journal: Neuroscience letters 20050801

Title: Involvement of p38-mitogen-activated protein kinase in adenosine receptor-mediated relaxation of coronary artery.

Journal: American journal of physiology. Heart and circulatory physiology 20050601

Title: Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosine.

Journal: Investigative ophthalmology & visual science 20050601

Title: The role of adenosine A(1) receptors in the interaction between amygdala and entorhinal cortex of kindled rats.

Journal: Epilepsy research 20050601

Title: Novel mitogenic effect of adenosine on coronary artery smooth muscle cells: role for the A1 adenosine receptor.

Journal: Circulation research 20050513

Title: Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.

Journal: Neurobiology of learning and memory 20050501

Title: [Therapeutic efficacy of N6-cyclopentyladenosine against acute dichlorvos poisoning].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20050401

Title: A series of ligands displaying a remarkable agonistic-antagonistic profile at the adenosine A1 receptor.

Journal: Journal of medicinal chemistry 20050324

Title: A 'locked-on,' constitutively active mutant of the adenosine A1 receptor.

Journal: European journal of pharmacology 20050307

Title: Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.

Journal: British journal of pharmacology 20050301

Title: Reversal of neuromuscular effects of adenosine by specific adenosine A1-receptor antagonist in live rats.

Journal: The International journal of neuroscience 20050301

Title: Modulating effect of adenosine deaminase on function of adenosine A1 receptors.

Journal: Acta pharmacologica Sinica 20050201

Title: Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines.

Journal: Journal of medicinal chemistry 20050113

Title: N6-cyclopentyladenosine inhibits proliferation of murine haematopoietic progenitor cells in vivo.

Journal: European journal of pharmacology 20050110

Title: Adenosine postsynaptically modulates supraoptic neuronal excitability.

Journal: Journal of neurophysiology 20050101

Title: Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: Brain penetration of synthetic adenosine A1 receptor agonists in situ: role of the rENT1 nucleoside transporter and binding to blood constituents.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101

Title: Ageing-related decline in adenosine A1 receptor binding in the rat brain: an autoradiographic study.

Journal: Journal of neuroscience research 20041201

Title: Activation of PLC-delta1 by Gi/o-coupled receptor agonists.

Journal: American journal of physiology. Cell physiology 20041201

Title: 2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors.

Journal: Biochemical pharmacology 20041115

Title: Effects of adenosine on optic nerve head circulation in rabbits.

Journal: Experimental eye research 20041101

Title: Activation of protein kinase B by adenosine A1 and A3 receptors in newborn rat cardiomyocytes.

Journal: Journal of molecular and cellular cardiology 20041101

Title: Effect of omeprazole on gastric adenosine A1 and A2A receptor gene expression and function.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training.

Journal: Clinical and experimental pharmacology & physiology 20041001

Title: Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.

Journal: European journal of pharmacology 20040924

Title: Adenosine A(1)-receptor-mediated tonic inhibition of glutamate release at rat hippocampal CA3-CA1 synapses is primarily due to inhibition of N-type Ca(2+) channels.

Journal: European journal of pharmacology 20040924

Title: Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Journal: European journal of pharmacology 20040919

Title: Clearance of cyclopentyladenosine and cyclohexyladenosine in rats following a single subcutaneous dose.

Journal: Pharmacological research 20040901

Title: Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy.

Journal: Neuropharmacology 20040901

Title: Concentration estimation via curve fitting: quantification of negative inotropic agents by using a simple mathematical method in guinea pig atria.

Journal: Bulletin of mathematical biology 20040901

Title: Pharmacological characterization of FR194921, a new potent, selective, and orally active antagonist for central adenosine A1 receptors.

Journal: Journal of pharmacological sciences 20040901

Title: Atrial natriuretic peptide modulates the hyperpolarization-activated current (If) in human atrial myocytes.

Journal: Cardiovascular research 20040815

Title: Role of adenosine A1 receptor in the regulation of gastrin release.

Journal: The Journal of pharmacology and experimental therapeutics 20040801

Title: The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference.

Journal: Nature neuroscience 20040801

Title: Simultaneous recording of eeg and direct current (DC) potential makes it possible to assess functional and metabolic state of nervous tissue.

Journal: The International journal of neuroscience 20040801

Title: Regulation by equilibrative nucleoside transporter of adenosine outward currents in adult rat spinal dorsal horn neurons.

Journal: Brain research bulletin 20040730

Title: Structure-affinity relationships of 5'-aromatic ethers and 5'-aromatic sulfides as partial A1 adenosine agonists, potential supraventricular anti-arrhythmic agents.

Journal: Bioorganic & medicinal chemistry letters 20040716

Title: Comparative analysis of putative agonist-binding modes in the human A1 adenosine receptor.

Journal: Chembiochem : a European journal of chemical biology 20040607

Title: An IgM class anti-neutrophil cytoplasm antibody inhibits neutrophil adhesion and apoptosis via a Syk dependent signaling cascade.

Journal: Molecular immunology 20040601

Title: The role of intraspinal adenosine A1 receptors in sympathetic regulation.

Journal: European journal of pharmacology 20040510

Title: Role of adenosine A2A receptor in the regulation of gastric somatostatin release.

Journal: The Journal of pharmacology and experimental therapeutics 20040501

Title: Pharmacological manipulations of ATP-dependent potassium channels and adenosine A1 receptors do not impact hippocampal ischemic preconditioning in vivo: evidence in a highly quantitative gerbil model.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040501

Title: Adenosine A1 receptor agonists block the neuropathological changes in rat retrosplenial cortex after administration of the NMDA receptor antagonist dizocilpine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301

Title: Organophosphate-induced convulsions and prevention of neuropathological damages.

Journal: Toxicology 20040301

Title: Lack of adenosine A1 and dopamine D2 receptor-mediated modulation of the cardiovascular effects of the adenosine A2A receptor agonist CGS 21680.

Journal: European journal of pharmacology 20040126

Title: Effect of the K+(ATP) channel opener, KCO912, on baseline and allergen induced airway hyperresponsiveness in allergic rabbits.

Journal: European journal of pharmacology 20040126

Title: Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.

Journal: Neuroscience letters 20040123

Title: Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor.

Journal: Bioorganic & medicinal chemistry 20040102

Title: Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning.

Journal: Archives of toxicology 20040101

Title: Partial A(1) adenosine receptor agonists from a molecular perspective and their potential use as chronic ventricular rate control agents during atrial fibrillation (AF).

Journal: Current topics in medicinal chemistry 20040101

Title: Effects of stable adenosine receptor agonists on bone marrow hematopoietic cells as inferred from the cytotoxic action of 5-fluorouracil.

Journal: Physiological research 20040101

Title: Sleep regulation in adenosine A2A receptor-deficient mice.

Journal: Neurology 20031209

Title: Adenosine modulation of [Ca2+]i in cerebellar granular cells: multiple adenosine receptors involved.

Journal: Brain research 20031205

Title: Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.

Journal: The Journal of physiology 20031201

Title: Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism.

Journal: General physiology and biophysics 20031201

Title: Cyclopentyladenosine and some of its low-efficacy derivatives inhibit striatal synaptosomal release of acetylcholine to a similar degree.

Journal: European journal of pharmacology 20031128

Title: Effect of drugs active at adenosine receptors upon chronic stress-induced hyperalgesia in rats.

Journal: European journal of pharmacology 20031128

Title: Blood-brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031101

Title: Effect of taurine deficiency on adenosine receptor-mediated relaxation of the rat aorta.

Journal: Vascular pharmacology 20031101

Title: Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.

Journal: Neuropharmacology 20031001

Title: Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030901

Title: Circulating triglyceride lipolysis facilitates lipoprotein lipase translocation from cardiomyocyte to myocardial endothelial lining.

Journal: Cardiovascular research 20030901

Title: Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats.

Journal: The European journal of neuroscience 20030801

Title: Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701

Title: The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701

Title: Bimodal acute effects of A1 adenosine receptor activation on Na+/H+ exchanger 3 in opossum kidney cells.

Journal: Journal of the American Society of Nephrology : JASN 20030701

Title: Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos.

Journal: The European journal of neuroscience 20030701

Title: Partial adenosine A(1) receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice.

Journal: European journal of pharmacology 20030620

Title: A role of protein kinase C mu in signalling from the human adenosine A1 receptor to the nucleus.

Journal: British journal of pharmacology 20030601

Title: Low efficacy adenosine A1 agonists inhibit striatal acetylcholine release in rats improving central selectivity of action.

Journal: Neuroscience letters 20030529

Title: Streptozotocin-induced diabetes modulates presynaptic and postsynaptic function in the rat ileum.

Journal: European journal of pharmacology 20030523

Title: Adenosine A1 receptor agonist N6-cyclopentyladenosine affects the inactivation of acetylcholinesterase in blood and brain by sarin.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons.

Journal: Journal of neurophysiology 20030301

Title: Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.

Journal: European journal of pharmacology 20030124

Title: Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo.

Journal: Journal of the American Society of Nephrology : JASN 20030101

Title: [Protective effect of A-agonists in a minimum invasive model of spinal cord ischemia in rats].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20030101

Title: Increase in adenosine A1 receptor gene expression in the liver of streptozotocin-induced diabetic rats.

Journal: Diabetes/metabolism research and reviews 20030101

Title: Individual and combined effects of N6-cyclopentyladenosine, flunarizine and diazepam on aminophylline-induced recurrent generalized seizures in mice.

Journal: Polish journal of pharmacology 20030101

Title: Pertussis toxin-sensitive G proteins mediate the inhibition of basal phosphoinositide metabolism caused by adenosine A1 receptors in rat hippocampal slices.

Journal: Neurochemical research 20021201

Title: Formalin-induced pain and mu-opioid receptor density in brain and spinal cord are modulated by A1 and A2a adenosine agonists in mice.

Journal: Brain research 20021129

Title: Effects of the adenosine A1 receptor allosteric modulators PD 81,723 and LUF 5484 on the striatal acetylcholine release.

Journal: European journal of pharmacology 20021115

Title: Saturation of neuroprotective effects of adenosine in cortical culture.

Journal: Neuroreport 20021115

Title: Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication.

Journal: Archives of toxicology 20021101

Title: Reduction in intracellular calcium levels induces injury in developing neurons.

Journal: Experimental neurology 20021101

Title: Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats.

Journal: Pharmacology, biochemistry, and behavior 20021001

Title: Capacitation state-dependent changes in adenosine receptors and their regulation of adenylyl cyclase/cAMP.

Journal: Molecular reproduction and development 20021001

Title: Antiadrenergic effects of adenosine A(1) receptor-mediated protein phosphatase 2a activation in the heart.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Mechanisms mediating regional sympathoactivatory responses to stimulation of NTS A(1) adenosine receptors.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Possible role of mast cells in cineole-induced scratching behavior in mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

Title: Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors.

Journal: Journal of natural products 20021001

Title: Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.

Journal: Journal of medicinal chemistry 20020926

Title: Interactions of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors.

Journal: Life sciences 20020906

Title: The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance.

Journal: Neurobiology of learning and memory 20020901

Title: Poly(lactic acid) microspheres for the sustained release of antiischemic agents.

Journal: International journal of pharmaceutics 20020821

Title: Suppression of adenosine A(3) receptor-mediated hypotension and mast cell degranulation in the rat by dexamethasone.

Journal: The Journal of pharmacology and experimental therapeutics 20020801

Title: Agonist-promoted heteromeric oligomerization between adenosine A(1) and P2Y(1) receptors in living cells.

Journal: FEBS letters 20020717

Title: Facilitation of noradrenaline release by adenosine A(2A) receptors in the epididymal portion and adenosine A(2B) receptors in the prostatic portion of the rat vas deferens.

Journal: European journal of pharmacology 20020712

Title: A1 adenosine receptor activation induces ventriculomegaly and white matter loss.

Journal: Neuroreport 20020702

Title: Chronic caffeine treatment causes changes in cardiac adenosine receptor function in rats.

Journal: Pharmacology 20020701

Title: Adenosine A(1)-receptor induced late preconditioning and myocardial infarction: reperfusion duration is critical.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Dose-dependent activation of antiapoptotic and proapoptotic pathways by ethanol treatment in human vascular endothelial cells: differential involvement of adenosine.

Journal: The Journal of biological chemistry 20020607

Title: Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020601

Title: Molecular aspects of acute inhibition of Na(+)-H(+) exchanger NHE3 by A(2)-adenosine receptor agonists.

Journal: The Journal of physiology 20020601

Title: Effects of adenosine receptor agonists on guinea-pig isolated working hearts and the role of endothelium and NO.

Journal: The Journal of pharmacy and pharmacology 20020601

Title: Dopamine D1 receptors and adenosine A1 receptors in the rat nucleus accumbens regulate motor activity but not prepulse inhibition.

Journal: European journal of pharmacology 20020531

Title: 2-Chloro-N(6)-cyclopentyladenosine, adenosine A(1) receptor agonist, antagonizes the adenosine A(3) receptor.

Journal: European journal of pharmacology 20020517

Title: Release inhibitory receptors activation favours the A2A-adenosine receptor-mediated facilitation of noradrenaline release in isolated rat tail artery.

Journal: British journal of pharmacology 20020501

Title: Effects of the adenosine A(1) receptor agonist N(6)-cyclopentyladenosine on phencyclidine-induced behavior and expression of the immediate-early genes in the discrete brain regions of rats.

Journal: Brain research. Molecular brain research 20020430

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Adenosine receptor-mediated control of in vitro release of pain-related neuropeptides from the rat spinal cord.

Journal: European journal of pharmacology 20020419

Title: Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues.

Journal: Journal of medicinal chemistry 20020314

Title: Role of P(1) purinergic receptors in myocardial ischemia sensory transduction.

Journal: Cardiovascular research 20020301

Title: Regulation of glycogen metabolism in hepatocytes through adenosine receptors. Role of Ca2+ and cAMP.

Journal: European journal of pharmacology 20020222

Title: Blockade of adenosine A1 receptors in the posterior cingulate cortex facilitates memory in rats.

Journal: European journal of pharmacology 20020222

Title: Effects of adenosine agonists on consumptive behaviour and body temperature.

Journal: The Journal of pharmacy and pharmacology 20020201

Title: Functional characterization of an endogenous Xenopus oocyte adenosine receptor.

Journal: British journal of pharmacology 20020101

Title: [Protective effect of cyclopentyladenosine in a minimally invasive model of acute cerebral focal ischemia in rats].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20020101

Title: Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.

Journal: Neuroscience 20020101

Title: Interactions among adenosine deaminase, adenosine A(1) receptors and dopamine D(1) receptors in stably cotransfected fibroblast cells and neurons.

Journal: Neuroscience 20020101

Title: Lipopolysaccharide binds to and activates A(1) adenosine receptors on human pulmonary artery endothelial cells.

Journal: Journal of endotoxin research 20020101

Title: Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum.

Journal: BMC neuroscience 20020101

Title: Cocaine-induced hyperactivity is more influenced by adenosine receptor agonists than amphetamine-induced hyperactivity.

Journal: Polish journal of pharmacology 20020101

Title: [Protective effect of adenosine receptor agonists in a model of spinal cord injury in rats].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20020101

Title: Adenosine modulates Mg(2+) uptake in distal convoluted tubule cells via A(1) and A(2) purinoceptors.

Journal: American journal of physiology. Renal physiology 20011201

Title: Adenosine regulates the IL-1 beta-induced cellular functions of human gingival fibroblasts.

Journal: International immunology 20011201

Title: Pharmacological delayed preconditioning against ischaemia-induced ventricular arrhythmias: effect of an adenosine A(1)-receptor agonist.

Journal: British journal of pharmacology 20011201

Title: Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.

Journal: Pain 20011201

Title: Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.

Journal: British journal of pharmacology 20011201

Title: Neuronal mechanisms of the anoxia-induced network oscillations in the rat hippocampus in vitro.

Journal: The Journal of physiology 20011015

Title: Suppression of presynaptic responses to adenosine by activation of NMDA receptors.

Journal: European journal of pharmacology 20010907

Title: The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.

Journal: British journal of pharmacology 20010901

Title: Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.

Journal: British journal of pharmacology 20010901

Title: Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.

Journal: British journal of pharmacology 20010901

Title: 5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors.

Journal: Journal of medicinal chemistry 20010830

Title: Interaction between angiotensin IV and adenosine A(1) receptor related drugs in passive avoidance conditioning in rats.

Journal: Behavioural brain research 20010827

Title: Adenosine A1 receptors reduce release from excitatory but not inhibitory synaptic inputs onto lateral horn neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815

Title: Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.

Journal: Life sciences 20010706

Title: Adenosine A(1) and A(2A) receptors modulate sleep state and breathing in fetal sheep.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010701

Title: Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor.

Journal: Brain research bulletin 20010701

Title: Poly(lactic acid) microspheres for the sustained release of a selective A1 receptor agonist.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010615

Title: Selective attenuation by adenosine of arrhythmogenic action of isoproterenol on ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20010601

Title: Stimulation by n6-cyclopentyladenosine of A1 adenosine receptors, coupled to galphai2 protein subunit, has a capacitative effect on human spermatozoa.

Journal: Biology of reproduction 20010601

Title: Inhibition of cell proliferation in the embryonic myocardium by A1 adenosine receptor activation.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20010601

Title: Anti-adrenergic effect of adenosine on Na(+)-Ca(2+) exchange current recorded from guinea-pig ventricular myocytes.

Journal: Cell calcium 20010501

Title: Effects of chronic morphine and N(6)-cyclopentyl-adenosine administration on kainic acid-induced status epilepticus.

Journal: Epilepsy research 20010501

Title: Ameliorative effects of paeoniflorin, a major constituent of peony root, on adenosine A1 receptor-mediated impairment of passive avoidance performance and long-term potentiation in the hippocampus.

Journal: Biological & pharmaceutical bulletin 20010501

Title: Electrically evoked release of glutamate in rat hippocampal slices: effects of various drugs and fimbria-fornix lesions.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010501

Title: Hormonal regulation of phospholipase D activity in Ca(2+) transporting cells of rabbit connecting tubule and cortical collecting duct.

Journal: Biochimica et biophysica acta 20010423

Title: Effect of an adenosine A(1) receptor agonist and a novel pyrimidoindole on membrane properties and neurotransmitter release in rat cortical and hippocampal neurons.

Journal: Neurochemistry international 20010401

Title: A depletable pool of adenosine in area CA1 of the rat hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010401

Title: Synthesis and study of 5'-ester prodrugs of N6-cyclopentyladenosine, a selective A1 receptor agonist.

Journal: Pharmaceutical research 20010401

Title: Synthesis and use of FSCPX, an irreversible adenosine A1 antagonist, as a 'receptor knock-down' tool.

Journal: Bioorganic & medicinal chemistry letters 20010326

Title: Determination of the adenosine A(1) agonist N(6)-cyclopentyladenosine in rat blood by solid-phase extraction and HPLC.

Journal: Journal of pharmaceutical and biomedical analysis 20010301

Title: Characterization of adenosine A1 receptor in cultured myoblast C2C12 cells of mice.

Journal: Autonomic neuroscience : basic & clinical 20010220

Title: Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells.

Journal: European journal of pharmacology 20010216

Title: Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201

Title: Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine.

Journal: Journal of molecular and cellular cardiology 20010201

Title: Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons.

Journal: Neuropharmacology 20010101

Title: Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: A partial agonist of the A(1)-adenosine receptor selectively slows AV conduction in guinea pig hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells.

Journal: American journal of physiology. Renal physiology 20010101

Title: The sulphydryl reagent, N-ethylmaleimide, disrupts sleep and blocks A1 adenosine receptor-mediated inhibition of intracellular calcium signaling in the in vitro ventromedial preoptic nucleus.

Journal: Neuroscience 20010101

Title: An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons.

Journal: Neuroscience 20010101

Title: [Comparative characteristics of A1-receptor agonists as neuroprotective agents].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: Regulation of leptin release and lipolysis by PGE2 in rat adipose tissue.

Journal: Prostaglandins & other lipid mediators 20001001

Title: Repeated adenosine pre-treatment potentiates the acute effect of methamphetamine in rats.

Journal: Japanese journal of pharmacology 20000901

Title: A1 adenosine receptor activation increases adipocyte leptin secretion.

Journal: Endocrinology 20000401

Title: N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor.

Journal: Journal of medicinal chemistry 20000127

Title: Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.

Journal: Molecular pharmacology 19991001

Title: Epileptogenic action of caffeine during anoxia in the neonatal rat hippocampus.

Journal: Annals of neurology 19990701

Title: Identification of the adenine binding site of the human A1 adenosine receptor.

Journal: The Journal of biological chemistry 19990205

Title: Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.

Journal: Biochemical pharmacology 19981201

Title: Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19981001

Title: Influence of adenosine agonists and antiepileptic drugs on theophylline-induced seizures in rats.

Journal: Indian journal of physiology and pharmacology 19981001

Title: 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.

Journal: Journal of medicinal chemistry 19980507

Title: Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19980101

Title: Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.

Journal: European journal of pharmacology 19970611

Title: Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19970115

Title: Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.

Journal: The Journal of biological chemistry 19941223

Title: Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.

Journal: The Journal of pharmacology and experimental therapeutics 19941201

Title: 2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.

Journal: Journal of medicinal chemistry 19941014

Title: Coupling of a transfected human brain A1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism.

Journal: British journal of pharmacology 19940401

Title: Molecular cloning and characterization of the human A3 adenosine receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19931101

Title: Klotz KN, et al. Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):382-91.

Title: Soliño M, et al. Adenosine A1 receptor: A neuroprotective target in light induced retinal degeneration. PLoS One. 2018 Jun 18;13(6):e0198838.

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Tags:41552-82-3 Molecular Formula|41552-82-3 MDL|41552-82-3 SMILES|41552-82-3 N6-CYCLOPENTYLADENOSINE