Home Quinolines 42923-77-3
42923-77-3,MFCD01717129
Catalog No.:AA00BX88

42923-77-3 | 6-Methoxy-1,2,3,4-tetrahydroisoquinoline

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100mg
97%
in stock  
$16.00   $11.00
- +
250mg
97%
in stock  
$22.00   $15.00
- +
500mg
95%
in stock  
$38.00   $27.00
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1g
97%
in stock  
$44.00   $31.00
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5g
97%
in stock  
$178.00   $125.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BX88
Chemical Name:
6-Methoxy-1,2,3,4-tetrahydroisoquinoline
CAS Number:
42923-77-3
Molecular Formula:
C10H13NO
Molecular Weight:
163.2163
MDL Number:
MFCD01717129
SMILES:
COc1ccc2c(c1)CCNC2
Properties
Computed Properties
 
Complexity:
149  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.3  

Upstream Synthesis Route

[1]AdvancedSynthesisandCatalysis,2012,vol.354,#16,p.3045-3053

[2]IndianJournalofChemistry,SectionB:OrganicChemistryIncludingMedicinalChemistry,1993,vol.32,#12,p.1209-1213

[3]Organometallics,2018,vol.37,#4,p.584-591

[4]Patent:US4812573,1989,A,

[5]JournaloftheAmericanChemicalSociety,1947,vol.69,p.1939,1941

[1]AdvancedSynthesisandCatalysis,2017,vol.359,#14,p.2358-2363

[1]BioorganicandMedicinalChemistry,2008,vol.16,#12,p.6364-6370

[2]JournaloftheAmericanChemicalSociety,1934,vol.56,p.1769

[3]Patent:US6495562,2002,B1,

[4]Patent:US6504031,2003,B1,

[5]BioorganicandMedicinalChemistryLetters,2007,vol.17,#24,p.6841-6846

[6]BioorganicandMedicinalChemistryLetters,2010,vol.20,#17,p.5269-5273

[1]JournalofMedicinalChemistry,1987,vol.30,#12,p.2208-2216

[2]IndianJournalofChemistry,SectionB:OrganicChemistryIncludingMedicinalChemistry,1993,vol.32,#12,p.1209-1213

[3]BioorganicandMedicinalChemistry,2016,vol.24,#2,p.207-219

[4]BioorganicandMedicinalChemistry,2016,vol.24,#4,p.789-801

[5]BioorganicandMedicinalChemistry,2015,vol.23,#21,p.6855-6868

[6]BioorganicandMedicinalChemistryLetters,2001,vol.11,#14,p.1885-1888

[7]Patent:WO2012/97682,2012,A1,.Locationinpatent:Page/Pagecolumn134

[8]Patent:WO2012/97684,2012,A1,.Locationinpatent:Page/Pagecolumn108-109

[9]Patent:WO2013/80222,2013,A1,.Locationinpatent:Page/Pagecolumn39

[10]Patent:US2016/24063,2016,A1,.Locationinpatent:Paragraph0268-0270

[11]Patent:EP3207928,2017,A2,.Locationinpatent:Paragraph0162-0164

[1]BioorganicandMedicinalChemistryLetters,2008,vol.18,#16,p.4727-4730

[2]JournalofChemicalResearch,Miniprint,1987,#2,p.501-526

[3]HelveticaChimicaActa,1924,vol.7,p.955

[4]JournaloftheAmericanChemicalSociety,1934,vol.56,p.1769

[5]BioorganicandMedicinalChemistry,2002,vol.10,#1,p.87-95

[6]BioorganicandMedicinalChemistryLetters,2007,vol.17,#24,p.6841-6846

[7]BioorganicandMedicinalChemistryLetters,2010,vol.20,#17,p.5269-5273

[8]OrganicProcessResearchandDevelopment,2007,vol.11,#3,p.463-465

[9]Patent:WO2007/106349,2007,A2,.Locationinpatent:Page/Pagecolumn61

Downstream Synthesis Route
2917-91-1    42923-77-3   
1-diethylamino-3-(6-methoxy-3,4-dihydro-1<i>H</i>-2isoquinolyl)-propan-2-ol 

[1]Patent:US1845403,1929,

[1]ChemicalandPharmaceuticalBulletin,2012,vol.60,p.945-948

[2]JournaloftheChemicalSociety,1958,p.1967,1973

[1]BioorganicandMedicinalChemistry,2008,vol.16,p.6364-6370

[2]JournaloftheAmericanChemicalSociety,1934,vol.56,p.1769

[3]Patent:US6495562,2002,B1

[4]Patent:US6504031,2003,B1

[5]BioorganicandMedicinalChemistryLetters,2007,vol.17,p.6841-6846

[6]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.5269-5273

[1]Tetrahedron,1992,vol.48,p.8739-8750

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

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