[1]BioorganicandMedicinalChemistryLetters,2005,vol.15,p.5039-5044
Title: Mechanical force-mediated pathological cartilage thinning is regulated by necroptosis and apoptosis.
Journal: Osteoarthritis and cartilage 20170801
Title: Necroptosis contributes to methamphetamine-induced cytotoxicity in rat cortical neurons.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160901
Title: FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells.
Journal: Toxicology letters 20150702
Title: The role of RIP3 mediated necroptosis in ouabain-induced spiral ganglion neurons injuries.
Journal: Neuroscience letters 20140822
Title: Role of receptor interacting protein (RIP)1 on apoptosis-inducing factor-mediated necroptosis during acetaminophen-evoked acute liver failure in mice.
Journal: Toxicology letters 20140321
Title: Akt and mTOR mediate programmed necrosis in neurons.
Journal: Cell death & disease 20140201
Title: The molecular mechanisms and gene expression profiling for shikonin-induced apoptotic and necroptotic cell death in U937 cells.
Journal: Chemico-biological interactions 20130925
Title: Cobalt triggers necrotic cell death and atrophy in skeletal C2C12 myotubes.
Journal: Toxicology and applied pharmacology 20130901
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Necrostatin-1 blocks both RIPK1 and IDO: consequences for the study of cell death in experimental disease models.
Journal: Cell death and differentiation 20130201
Title: The targeted inhibition of mitochondrial Hsp90 overcomes the apoptosis resistance conferred by Bcl-2 in Hep3B cells via necroptosis.
Journal: Toxicology and applied pharmacology 20130101
Title: RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy.
Journal: International immunopharmacology 20121201
Title: Necrostatin-1 protects photoreceptors from cell death and improves functional outcome after experimental retinal detachment.
Journal: The American journal of pathology 20121101
Title: Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models.
Journal: Cell death & disease 20121101
Title: Staurosporine induces apoptosis and necroptosis in cultured rat astrocytes.
Journal: Drug and chemical toxicology 20121001
Title: Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia.
Journal: Neuroscience 20120906
Title: Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1.
Journal: Analytical biochemistry 20120815
Title: Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells.
Journal: Die Pharmazie 20120801
Title: Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.
Journal: Basic research in cardiology 20120701
Title: Necroptosis modulated by autophagy is a predominant form of melanoma cell death induced by sanguilutine.
Journal: Biological chemistry 20120701
Title: Fas ligand-Fas signaling participates in light-induced apoptotic death in photoreceptor cells.
Journal: Investigative ophthalmology & visual science 20120601
Title: PI3K inhibitor D-116883 is effective in in vitro models of ovarian cancer.
Journal: Anticancer research 20120501
Title: Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis.
Journal: The Journal of biological chemistry 20120427
Title: Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury.
Journal: Kidney international 20120401
Title: Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
Journal: Blood 20120308
Title: Glutamate oxidative injury to RGC-5 cells in culture is necrostatin sensitive and blunted by a hydrogen sulfide (H2S)-releasing derivative of aspirin (ACS14).
Journal: Neurochemistry international 20120301
Title: Nec-1 enhances shikonin-induced apoptosis in leukemia cells by inhibition of RIP-1 and ERK1/2.
Journal: International journal of molecular sciences 20120101
Title: RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome.
Journal: Immunity 20111223
Title: Water-soluble germanium nanoparticles cause necrotic cell death and the damage can be attenuated by blocking the transduction of necrotic signaling pathway.
Journal: Toxicology letters 20111215
Title: Necroptosis is a novel mechanism of radiation-induced cell death in anaplastic thyroid and adrenocortical cancers.
Journal: Surgery 20111201
Title: NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic β-cells.
Journal: FEBS letters 20111003
Title: Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells.
Journal: Biochemical and biophysical research communications 20110805
Title: 24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis.
Journal: The Journal of biological chemistry 20110715
Title: MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1.
Journal: Journal of cellular and molecular medicine 20110701
Title: The dual functions of receptor interacting protein 1 in fas-induced hepatocyte death during sepsis.
Journal: Shock (Augusta, Ga.) 20110501
Title: Light- and sodium azide-induced death of RGC-5 cells in culture occurs via different mechanisms.
Journal: Apoptosis : an international journal on programmed cell death 20110401
Title: Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101
Title: RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation.
Journal: PloS one 20110101
Title: Cyclophilin A release as a biomarker of necrotic cell death.
Journal: Cell death and differentiation 20101201
Title: Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury.
Journal: Brain research 20101008
Title: The role of PARP activation in glutamate-induced necroptosis in HT-22 cells.
Journal: Brain research 20100709
Title: Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model.
Journal: Journal of neuroscience research 20100515
Title: Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis.
Journal: Free radical biology & medicine 20100115
Title: Novel interventions targeting on apoptosis and necrosis induced by aluminum chloride in neuroblastoma cells.
Journal: Journal of biological regulators and homeostatic agents 20100101
Title: Enhanced tissue integration during cartilage repair in vitro can be achieved by inhibiting chondrocyte death at the wound edge.
Journal: Tissue engineering. Part A 20090701
Title: Attenuation of cadmium-induced necrotic cell death by necrostatin-1: potential necrostatin-1 acting sites.
Journal: Toxicology and applied pharmacology 20090301
Title: 3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells.
Journal: Toxicology 20090131
Title: Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons.
Journal: Neuroscience letters 20081212
Title: Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Identification of RIP1 kinase as a specific cellular target of necrostatins.
Journal: Nature chemical biology 20080501
Title: Acute myeloid leukemia-targeted toxin activates both apoptotic and necroptotic death mechanisms.
Journal: PloS one 20080101
Title: Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells.
Journal: Journal of neurochemistry 20071201
Title: The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore.
Journal: Cardiovascular drugs and therapy 20071201
Title: Necrostatin: a potentially novel cardioprotective agent?
Journal: Cardiovascular drugs and therapy 20070801
Title: Sitosterol-containing lipoproteins trigger free sterol-induced caspase-independent death in ACAT-competent macrophages.
Journal: The Journal of biological chemistry 20061103
Title: Structure-activity relationship study of novel necroptosis inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20051115
Title: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Journal: Nature chemical biology 20050701
Title: Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.
Journal: Nature medicine 20050301
Title: Structural requirements for hydantoins and 2-thiohydantoins to induce lymphoproliferative popliteal lymph node reactions in the mouse.
Journal: International journal of immunopharmacology 19880101
Title: Degterev A, et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol. 2005 Jul;1(2):112-9.
Title: Linkermann A, et al. The RIP1-kinase inhibitor necrostatin-1 prevents osmotic nephrosis and contrast-induced AKI in mice. J Am Soc Nephrol. 2013 Oct;24(10):1545-57.
Title: Huang C, et al. Shikonin kills glioma cells through necroptosis mediated by RIP-1. PLoS One. 2013 Jun 28;8(6):e66326.
Title: Feyen D, et al. Increasing short-term cardiomyocyte progenitor cell (CMPC) survival by necrostatin-1 did not further preserve cardiac function. Cardiovasc Res. 2013 Jul 1;99(1):83-91.
Title: Zhou K, et al. RIP1-RIP3-DRP1 pathway regulates NLRP3 inflammasome activation following subarachnoid hemorrhage. Exp Neurol. 2017 Sep;295:116-124.
