Name: Name:4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBALDEHYDE
Brand: AABLOCKS
SKU: AA00D9L7
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00D9L7

Chemical Name: 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBALDEHYDE

CAS Number: 438577-61-8

Molecular Formula: C12H8F3NOS

Molecular Weight: 271.2582

MDL Number: MFCD23142747

SMILES: O=Cc1sc(nc1C)c1ccc(cc1)C(F)(F)F

Properties

Complexity: 302

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 18

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 3.7

Downstream Synthesis Route

438577-61-8

2393-17-1

885102-00-1

[1]BioorganicandMedicinalChemistryLetters,2006,vol.16,p.1840-1845

438577-61-8

15118-60-2

4-(4-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethyl-amino}-phenyl)-butyricacid

[1]BioorganicandMedicinalChemistryLetters,2006,vol.16,p.1840-1845

72505-21-6

438577-61-8

[1]JournalofMedicinalChemistry,2007,vol.50,p.685-695

[2]JournalofMedicinalChemistry,2013,vol.56,p.2975-2990

175277-03-9

438577-61-8

[1]Sierra,MichaelL.;Beneton,Véronique;Boullay,Anne-Bénédict;Boyer,Thierry;Brewster,AndrewG.;Donche,Frédéric;Forest,Marie-Claire;Fouchet,Marie-Hélène;Gellibert,FrançoiseJ.;Grillot,DidierA.;Lambert,MillardH.;Laroze,Alain;LeGrumelec,Christelle;Linget,JeanMichel;Montana,ValerieG.;Nguyen,Van-Loc;Nicodème,Edwige;Patel,Vipul;Penfornis,Annie;Pineau,Olivier;Pohin,Danig;Potvain,Florent;Poulain,Géraldine;Ruault,CécileBertho;Saunders,Michael;Toum,Jérôme;Xu,H.Eric;Xu,RobertX.;Pianetti,PascalM.[JournalofMedicinalChemistry,2007,vol.50,#4,p.685-695]

[2]Murugesan,Dinakaran;Mital,Alka;Kaiser,Marcel;Shackleford,DavidM.;Morizzi,Julia;Katneni,Kasiram;Campbell,Michael;Hudson,Alan;Charman,SusanA.;Yeates,Clive;Gilbert,IanH.[JournalofMedicinalChemistry,2013,vol.56,#7,p.2975-2990]

[3]Kesari,Chekrapani;Rama,KoteshwarRao;Sedighi,Khwajanezrabodin;Stenvang,Jan;Björkling,Fredrik;Kankala,Shravankumar;Thota,Niranjan[SyntheticCommunications,2021,vol.51,#9,p.1406-1416]

438577-61-8

579-74-8

1-(2-methoxyphenyl)-3-(4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)prop-2-en-1-one

[1]Kesari,Chekrapani;Rama,KoteshwarRao;Sedighi,Khwajanezrabodin;Stenvang,Jan;Björkling,Fredrik;Kankala,Shravankumar;Thota,Niranjan[SyntheticCommunications,2021,vol.51,#9,p.1406-1416]

438577-61-8 | 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBALDEHYDE