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Home Other Building Blocks 439239-90-4
439239-90-4,MFCD18633238
Catalog No.:AA00DB3R

439239-90-4 | Lasmiditan

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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DB3R
Chemical Name:
Lasmiditan
CAS Number:
439239-90-4
Molecular Formula:
C19H18F3N3O2
Molecular Weight:
377.3603
MDL Number:
MFCD18633238
SMILES:
CN1CCC(CC1)C(=O)c1cccc(n1)NC(=O)c1c(F)cc(cc1F)F
Properties
Computed Properties
 
Complexity:
530  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.8  

Literature

Title: Emerging treatment for chronic migraine and refractory chronic migraine.

Journal: Expert opinion on emerging drugs 20120901

Title: The 5-HT1F receptor agonist lasmiditan as a potential treatment of migraine attacks: a review of two placebo-controlled phase II trials.

Journal: The journal of headache and pain 20120601

Title: Defining and refining 5-HT receptor targets for migraine.

Journal: The Lancet. Neurology 20120501

Title: Efficacy and tolerability of lasmiditan, an oral 5-HT(1F) receptor agonist, for the acute treatment of migraine: a phase 2 randomised, placebo-controlled, parallel-group, dose-ranging study.

Journal: The Lancet. Neurology 20120501

Title: Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan. A comment.

Journal: Cephalalgia : an international journal of headache 20110701

Title: Treatment of migraine: update on new therapies.

Journal: Current opinion in neurology 20110601

Title: Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.

Journal: Cephalalgia : an international journal of headache 20101001

Title: Acute treatment of migraine with the selective 5-HT1F receptor agonist lasmiditan--a randomised proof-of-concept trial.

Journal: Cephalalgia : an international journal of headache 20101001

Title: Molecule of the month. Lasmiditan hydrochloride.

Journal: Drug news & perspectives 20100901

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SDS
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