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439692-52-1,MFCD04973929
Catalog No.:AA00DFKR

439692-52-1 | 4-Chloro-6-isopropylthieno[2,3-d]pyrimidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
500mg
95%
in stock  
$32.00   $23.00
- +
1g
95%
in stock  
$62.00   $43.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DFKR
Chemical Name:
4-Chloro-6-isopropylthieno[2,3-d]pyrimidine
CAS Number:
439692-52-1
Molecular Formula:
C9H9ClN2S
Molecular Weight:
212.6992
MDL Number:
MFCD04973929
SMILES:
CC(c1sc2c(c1)c(Cl)ncn2)C
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
189  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
3.7  

Downstream Synthesis Route
439692-52-1    160358-09-8   
3-((4-(6-Chlorothieno1,3-dpyrimidin-4-ylaimino)piperidin-1-yl)methyl)benzaamide,Monomaleate 
 
N-(1-(3,5-difluorobenzyl)piperidin-4-yl)-6-isopropylthieno2,3-dpyrimidin-4-amine 

[1]CurrentPatentAssignee:ABBVIEINC-US2005/222175,2005,A1

502651-65-2   
N-(1-(3,5-Difluorobenzyl)piperidin-4-yl)-6-chlorothieno2,3-dpyrimidin-4-amine,Monomaleate 
  439692-52-1 

[1]CurrentPatentAssignee:ABBVIEINC-US2005/222175,2005,A1

[2]CurrentPatentAssignee:ABBVIEINC-US2005/222176,2005,A1

439692-52-1    160358-09-8   
3-((4-(6-Chlorothieno2,3-dpyrimidin-4-ylamino)piperidin-1-yl)methyl)benzamide,monomaleate 
 
N-(1-(3,5-difluorobenzyl)piperidin-4-yl)-6-isopropylthieno2,3-dpyrimidin-4-amine 

[1]CurrentPatentAssignee:ABBVIEINC-US2005/222176,2005,A1

[1]Locationinpatent:schemeortableHoriuchi,Takao;Chiba,Jun;Uoto,Kouichi;Soga,Tsunehiko[BioorganicandMedicinalChemistryLetters,2009,vol.19,#2,p.305-308]

[1]Locationinpatent:experimentalpartHoriuchi,Takao;Takeda,Yasuyuki;Haginoya,Noriyasu;Miyazaki,Masaki;Nagata,Motoko;Kitagawa,Mayumi;Akahane,Kouichi;Uoto,Kouichi[ChemicalandPharmaceuticalBulletin,2011,vol.59,#8,p.991-1002]

[2]Locationinpatent:schemeortableHoriuchi,Takao;Chiba,Jun;Uoto,Kouichi;Soga,Tsunehiko[BioorganicandMedicinalChemistryLetters,2009,vol.19,#2,p.305-308]

Literature

Title: Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Journal: Nature chemical biology 20120129

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SDS
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Tags:439692-52-1 Molecular Formula|439692-52-1 MDL|439692-52-1 SMILES|439692-52-1 4-Chloro-6-isopropylthieno[2,3-d]pyrimidine