Name: Name:2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid
Brand: AABLOCKS
SKU: AA00DART
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00DART

Chemical Name: 2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid

CAS Number: 441-28-1

Molecular Formula: C16H10FNO2

Molecular Weight: 267.2545

MDL Number: MFCD00616372

SMILES: Fc1ccc(cc1)c1nc2ccccc2c(c1)C(=O)O

Properties

Storage: 2-8℃;Keep in dry area;

Complexity: 354

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 20

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 3.5

Downstream Synthesis Route

91-56-5

403-42-9

441-28-1

[1]Nicolaie,E;Guengoer,T;Goyard,J;Cure,G;Fouquet,A;etal.[EuropeanJournalofMedicinalChemistry,1992,vol.27,#9,p.977-984]

[2]Ghodsi,Razieh;Azizi,Ebrahim;Ferlin,MariaGrazia;Pezzi,Vincenzo;Zarghi,Afshin[Lettersindrugdesignanddiscovery,2016,vol.13,#1,p.89-97]

[3]Ghodsi,Razieh;Azizi,Ebrahim;Ferlin,MariaGrazia;Pezzi,Vincenzo;Zarghi,Afshin[Lettersindrugdesignanddiscovery,2016,vol.13,#1,p.89-97]

[4]CurrentPatentAssignee:HENANNORMALUNIVERSITY-CN108358838,2018,ALocationinpatent:Paragraph0029;0033;0034

[5]Locationinpatent:experimentalpartGarudachari;Satyanarayana;Thippeswamy;Shivakumar;Shivananda;Hegde,Gurumurthy;Isloor,ArunM.[EuropeanJournalofMedicinalChemistry,2012,vol.54,p.900-906]

[6]Lei,Na;Ren,Qing-Ling;Liu,Ya-Ping;Li,Ji;Cong,Peng;Qin,Jie;Zhu,Hai-Liang[JournalofMolecularStructure,2014,vol.1067,#1,p.220-224]

[7]Li,Sai;Huang,Qiang;Liu,Yajing;Zhang,Xiaolong;Liu,Shuang;He,Chao;Gong,Ping[EuropeanJournalofMedicinalChemistry,2013,vol.64,p.62-73]

[8]Buu-Hoi;Hoan;Jacquignon[RecueildesTravauxChimiquesdesPays-Bas,1949,vol.68,p.781,785]

[9]CurrentPatentAssignee:MITSUICHEMICALS,INC.-US5627193,1997,A

[10]CurrentPatentAssignee:ROCHEHOLDINGAG-US4560692,1985,A

[11]Bonacorso,HelioG.;Nogara,PabloA.;Silva,FernandaD'A.;Rosa,WilianC.;Wiethan,CarsonW.;Zanatta,Nilo;Martins,MarcosA.P.;Rocha,JoãoB.T.[JournalofFluorineChemistry,2016,vol.190,p.31-40]

[12]CurrentPatentAssignee:HENANNORMALUNIVERSITY-CN109942547,2019,ALocationinpatent:Paragraph0029-0033

[13]Shaikh,SarfarazF.;Dhavan,PratikP.;Singh,PinkyR.;Vaidya;Jadhav;Ramana[RussianJournalofBioorganicChemistry,2021,vol.47,#2,p.572-583][Bioorg.Khim.]

452-58-4

441-28-1

1394063-84-3

[1]Locationinpatent:experimentalpartGarudachari;Satyanarayana;Thippeswamy;Shivakumar;Shivananda;Hegde,Gurumurthy;Isloor,ArunM.[EuropeanJournalofMedicinalChemistry,2012,vol.54,p.900-906]

441-28-1 | 2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid