Home Amines 4441-50-3
4441-50-3,MFCD01104092
Catalog No.:AA00D8FV

4441-50-3 | 2-Amino-3-cyclohexylpropanoic acid

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00D8FV
Chemical Name:
2-Amino-3-cyclohexylpropanoic acid
CAS Number:
4441-50-3
Molecular Formula:
C9H17NO2
Molecular Weight:
171.2368
MDL Number:
MFCD01104092
SMILES:
OC(=O)CCNC1CCCCC1
NSC Number:
12794
Properties
Computed Properties
 
Complexity:
153  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-0.3  

Literature

Title: Creation of a thermostable NADP⁺-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain A1 meso-diaminopimelate dehydrogenase by site-directed mutagenesis.

Journal: Biotechnology letters 20120901

Title: Experimental evaluation of CH-π interactions in a protein core.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120507

Title: Role of amino acid hydrophobicity, aromaticity, and molecular volume on IAPP(20-29) amyloid self-assembly.

Journal: Proteins 20120401

Title: Characterization of new stable ghrelin analogs with prolonged orexigenic potency.

Journal: The Journal of pharmacology and experimental therapeutics 20120301

Title: Bifunctional μ/δ opioid peptides: variation of the type and length of the linker connecting the two components.

Journal: Chemical biology & drug design 20120201

Title: Radiolabelled peptides for oncological diagnosis.

Journal: European journal of nuclear medicine and molecular imaging 20120201

Title: Tuning β-sheet peptide self-assembly and hydrogelation behavior by modification of sequence hydrophobicity and aromaticity.

Journal: Biomacromolecules 20110711

Title: Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine.

Journal: Biopolymers 20110601

Title: Probing aromatic, hydrophobic, and steric effects on the self-assembly of an amyloid-β fragment peptide.

Journal: Molecular bioSystems 20110201

Title: Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity.

Journal: Biopolymers 20110101

Title: Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis.

Journal: PloS one 20110101

Title: A comparative study of the pharmacokinetics of traditional and automated dosing/blood sampling systems using gabapentin.

Journal: Indian journal of pharmacology 20110101

Title: The potential of antimicrobial peptides as biocides.

Journal: International journal of molecular sciences 20110101

Title: In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors.

Journal: Journal of the American Chemical Society 20100825

Title: Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs.

Journal: Marine drugs 20100101

Title: Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin.

Journal: PloS one 20100101

Title: The effect of increasing hydrophobicity on the self-assembly of amphipathic beta-sheet peptides.

Journal: Molecular bioSystems 20090901

Title: Development of inhibitors against lipase and alpha-glucosidase from derivatives of monascus pigment.

Journal: FEMS microbiology letters 20071101

Title: Expression levels of adenosine receptors in hippocampus and frontal cortex in argyrophilic grain disease.

Journal: Neuroscience letters 20070823

Title: 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV.

Journal: Bioorganic & medicinal chemistry letters 20070515

Title: Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.

Journal: Journal of medicinal chemistry 20070125

Title: Chemical and biological characterization of new Re(CO)3/[99mTc](CO)3 bombesin analogues.

Journal: Nuclear medicine and biology 20070101

Title: Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax.

Journal: Journal of translational medicine 20070101

Title: Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers.

Journal: ChemMedChem 20060301

Title: Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site.

Journal: The Journal of biological chemistry 20050506

Title: Ferrioxamine B analogues: targeting the FoxA uptake system in the pathogenic Yersinia enterocolitica.

Journal: Journal of the American Chemical Society 20050202

Title: Up-regulation of adenosine A1 receptor binding in pentylenetetrazol kindling in mice: effects of angiotensin IV.

Journal: Brain research 20050125

Title: Tuning stability of coiled-coil heterotrimers by selection of steric matching partners.

Journal: Organic letters 20041111

Title: Strand orientation by steric matching: a designed antiparallel coiled-coil trimer.

Journal: Journal of the American Chemical Society 20041110

Title: Investigation of the nature of the methionine-pi interaction in beta-hairpin peptide model systems.

Journal: Protein science : a publication of the Protein Society 20040901

Title: Comparison of C-H...pi and hydrophobic interactions in a beta-hairpin peptide: impact on stability and specificity.

Journal: Journal of the American Chemical Society 20040225

Title: Sample preparation and determination of gabapentin in venous and capillary blood using liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20040204

Title: Sequential and specific exchange of multiple coiled-coil components.

Journal: Journal of the American Chemical Society 20031029

Title: Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity.

Journal: Journal of medicinal chemistry 20030605

Title: Inhibition of human napsin A.

Journal: Protein and peptide letters 20030201

Title: Specific control of peptide assembly with combined hydrophilic and hydrophobic interfaces.

Journal: Journal of the American Chemical Society 20030122

Title: Peptide tic-tac-toe: heterotrimeric coiled-coil specificity from steric matching of multiple hydrophobic side chains.

Journal: Journal of the American Chemical Society 20020821

Title: Selective aromatic interactions in beta-hairpin peptides.

Journal: Journal of the American Chemical Society 20020814

Title: The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage.

Journal: Journal of molecular biology 20020301

Title: Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.

Journal: Biochemistry 20011120

Title: Coiled-coil formation governed by unnatural hydrophobic core side chains.

Journal: Journal of the American Chemical Society 20011107

Title: Physicochemical determinants of passive membrane permeability: role of solute hydrogen-bonding potential and volume.

Journal: Journal of medicinal chemistry 20011025

Title: Subsite specificity of trypanosomal cathepsin L-like cysteine proteases. Probing the S2 pocket with phenylalanine-derived amino acids.

Journal: European journal of biochemistry 20010501

Title: An activation switch in the ligand binding pocket of the C5a receptor.

Journal: The Journal of biological chemistry 20010202

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Tags:4441-50-3 Molecular Formula|4441-50-3 MDL|4441-50-3 SMILES|4441-50-3 2-Amino-3-cyclohexylpropanoic acid