Title: Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.
Journal: The Journal of biological chemistry 20140808
Title: Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20120801
Title: Flavivirus infection induces indoleamine 2,3-dioxygenase in human monocyte-derived macrophages via tumor necrosis factor and NF-κB.
Journal: Journal of leukocyte biology 20120401
Title: Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats.
Journal: Neuroscience letters 20120305
Title: IκB kinases modulate the activity of the androgen receptor in prostate carcinoma cell lines.
Journal: Neoplasia (New York, N.Y.) 20120301
Title: Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination.
Journal: Journal of biochemistry 20111201
Title: Targeting AML through DR4 with a novel variant of rhTRAIL.
Journal: Journal of cellular and molecular medicine 20111001
Title: AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts.
Journal: The Journal of biological chemistry 20110506
Title: Improved intraportal islet transplantation outcome by systemic IKK-beta inhibition: NF-κB activity in pancreatic islets depends on oxygen availability.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110201
Title: IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells.
Journal: PloS one 20110101
Title: IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.
Journal: PloS one 20110101
Title: Small molecule inhibitors of IkappaB kinase signaling inhibit osteoclast formation in vitro and prevent ovariectomy-induced bone loss in vivo.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101101
Title: In CD28-costimulated human naïve CD4+ T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms.
Journal: Immunology 20101001
Title: Up-regulation of bradykinin receptors in rat bronchi via I kappa B kinase-mediated inflammatory signaling pathway.
Journal: European journal of pharmacology 20100525
Title: Characterizing the involvement of the nuclear factor-kappa B (NF kappa B) transcription factor in uveal melanoma.
Journal: Investigative ophthalmology & visual science 20100401
Title: Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.
Journal: European journal of haematology 20100301
Title: Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells: studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release.
Journal: Expert opinion on investigational drugs 20100201
Title: A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour.
Journal: Journal of reproductive immunology 20100101
Title: Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma.
Journal: Cancer research 20091215
Title: The effect of microenvironmental CD40 signals on TRAIL- and drug-induced apoptosis in follicular lymphoma cells.
Journal: Scandinavian journal of immunology 20091201
Title: Tumor necrosis factor-alpha (TNF-alpha) induces upregulation of RhoA via NF-kappaB activation in cultured human bronchial smooth muscle cells.
Journal: Journal of pharmacological sciences 20090801
Title: Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090601
Title: p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090415
Title: Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy.
Journal: Molecular cancer therapeutics 20090301
Title: Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids.
Journal: Journal of medicinal chemistry 20080911
Title: Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.
Journal: International journal of oncology 20071201
Title: Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.
Journal: Arthritis and rheumatism 20071101
Title: The IKK inhibitor BMS-345541 affects multiple mitotic cell cycle transitions.
Journal: Cell cycle (Georgetown, Tex.) 20071015
Title: IFN-gamma-induced upregulation of Fcgamma-receptor-I during activation of monocytic cells requires the PKR and NFkappaB pathways.
Journal: Molecular immunology 20070101
Title: Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060415
Title: BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060201
Title: IKK mediates ischemia-induced neuronal death.
Journal: Nature medicine 20051201
Title: Collagen and aggrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkappaB kinase through suppression of metalloproteinase expression.
Journal: The Journal of pharmacology and experimental therapeutics 20051001
Title: Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkappaB-NF-kappaB pathway in IgE-dependent mast cell activation.
Journal: Journal of leukocyte biology 20050601
Title: Anti-inflammatory inhibitors of IkappaB kinase in asthma and COPD.
Journal: Current opinion in investigational drugs (London, England : 2000) 20041101
Title: A highly selective inhibitor of IkappaB kinase, BMS-345541, augments graft survival mediated by suboptimal immunosuppression in a murine model of cardiac graft rejection.
Journal: Transplantation 20040415
Title: An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20031201
Title: A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice.
Journal: Arthritis and rheumatism 20030901
Title: BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
Journal: The Journal of biological chemistry 20030117
