Catalog No.:AA00I8D8

445490-78-8 | 1-Boc-7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine

Name: Name:1-Boc-7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine
Brand: AABLOCKS
SKU: AA00I8D8
Availability: InStock
Rating: 90 (10 reviews)

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250mg

95%

in stock

$422.00 $295.00

- +

95%

in stock

$912.00 $639.00

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95%

in stock

$2,658.00 $1,861.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA00I8D8

Chemical Name:

1-Boc-7-(2-hydroxyethyl)-3,4-dihydro-1,8-naphthyridine

CAS Number:

445490-78-8

Molecular Formula:

C15H22N2O3

Molecular Weight:

278.3468

MDL Number:

MFCD19382454

SMILES:

OCCc1ccc2c(n1)N(CCC2)C(=O)OC(C)(C)C

Properties

Computed Properties

Complexity:

341

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

1.9

Downstream Synthesis Route

445490-78-8

243641-39-6

[1]Miller,WilliamH.;Manley,PeterJ.;Cousins,RussellD.;Erhard,KarlF.;Heerding,DirkA.;Kwon,Chet;Ross,StephenT.;Samanen,JamesM.;Takata,DennisT.;Uzinskas,IreneN.;Yuan,CatherineC.K.;Haltiwanger,R.Curtis;Gress,CatherineJ.;Lark,MichaelW.;Hwang,Shing-Mei;James,IanE.;Rieman,DavidJ.;Willette,RobertN.;Yue,Tian-Li;Azzarano,LeonardM.;Salyers,KevinL.;Smith,BrianR.;Ward,KeithW.;Johanson,KyungO.;Huffman,WilliamF.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#8,p.1483-1486]

[2]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-EP1218005,2004,B1Locationinpatent:Page22-23

243641-38-5

445490-78-8

[1]Locationinpatent:schemeortableHarris,CraigS.;Germain,Hervé;Pasquet,Georges[TetrahedronLetters,2008,vol.49,#41,p.5946-5949]

[2]CurrentPatentAssignee:JOHNSON&JOHNSONINC-US2003/18064,2003,A1

[3]Miller,WilliamH.;Manley,PeterJ.;Cousins,RussellD.;Erhard,KarlF.;Heerding,DirkA.;Kwon,Chet;Ross,StephenT.;Samanen,JamesM.;Takata,DennisT.;Uzinskas,IreneN.;Yuan,CatherineC.K.;Haltiwanger,R.Curtis;Gress,CatherineJ.;Lark,MichaelW.;Hwang,Shing-Mei;James,IanE.;Rieman,DavidJ.;Willette,RobertN.;Yue,Tian-Li;Azzarano,LeonardM.;Salyers,KevinL.;Smith,BrianR.;Ward,KeithW.;Johanson,KyungO.;Huffman,WilliamF.[BioorganicandMedicinalChemistryLetters,2003,vol.13,#8,p.1483-1486]

[4]Leonard,Kristi;Pan,Wenxi;Anaclerio,Beth;Gushue,JoanM.;Guo,Zihong;DesJarlais,ReneeL.;Chaikin,MargeA.;Lattanze,Jennifer;Crysler,Carl;Manthey,CarlL.;Tomczuk,BruceE.;Marugan,JuanJose[BioorganicandMedicinalChemistryLetters,2005,vol.15,#10,p.2679-2684]

[5]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-EP1218005,2004,B1Locationinpatent:Page22

2581-34-2

445490-78-8

445490-79-9

[1]Leonard,Kristi;Pan,Wenxi;Anaclerio,Beth;Gushue,JoanM.;Guo,Zihong;DesJarlais,ReneeL.;Chaikin,MargeA.;Lattanze,Jennifer;Crysler,Carl;Manthey,CarlL.;Tomczuk,BruceE.;Marugan,JuanJose[BioorganicandMedicinalChemistryLetters,2005,vol.15,#10,p.2679-2684]

[2]CurrentPatentAssignee:PDRADIOPHARMA-US2016/199520,2016,A1Locationinpatent:Paragraph0275;0288

[3]CurrentPatentAssignee:FUJIFILMHOLDINGSCORP.-JP2016/183151,2016,ALocationinpatent:Paragraph0310;0311;0324

938195-80-3

445490-78-8

959991-21-0

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2007/141473,2007,A1Locationinpatent:Page/Pagecolumn172-173

445490-78-8

912270-29-2

[1]Raboisson,Pierre;DesJarlais,ReneeL.;Reed,Rolanda;Lattanze,Jennifer;Chaikin,Margery;Manthey,CarlL.;Tomczuk,BruceE.;Marugan,JuanJose[EuropeanJournalofMedicinalChemistry,2007,vol.42,#3,p.334-343]

[2]CurrentPatentAssignee:T2YC;QINGYAOTONGCHUANGBEIJINGDRUGRESANDDEVELOPMEN-CN113354635,2021,ALocationinpatent:Paragraph0223-0226

[3]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2018/89355,2018,A1Locationinpatent:Page/Pagecolumn87

[4]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2006/108040,2006,A1Locationinpatent:Page/Pagecolumn15

Literature

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