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4510-34-3,MFCD22422327
Catalog No.:AA00DJJK

4510-34-3 | (Z)-3-Phenyl-2-propen-1-ol

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1g
>95%
2 weeks  
$841.00   $589.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DJJK
Chemical Name:
(Z)-3-Phenyl-2-propen-1-ol
CAS Number:
4510-34-3
Molecular Formula:
C9H10O
Molecular Weight:
134.1751
MDL Number:
MFCD22422327
SMILES:
OC/C=C\c1ccccc1
Properties
Properties
 
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
101  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.9  

Downstream Synthesis Route

[1]Zhong,Jian-Ji;Liu,Qiang;Wu,Cheng-Juan;Meng,Qing-Yuan;Gao,Xue-Wang;Li,Zhi-Jun;Chen,Bin;Tung,Chen-Ho;Wu,Li-Zhu[ChemicalCommunications,2016,vol.52,#9,p.1800-1803]

[2]Pelter,Andrew;Ward,RobertS.;Little,GillianM.[JournaloftheChemicalSociety.PerkintransactionsI,1990,#10,p.2775-2790]

[3]Xu,Bin;Tambar,UttamK.[JournaloftheAmericanChemicalSociety,2016,vol.138,#37,p.12073-12076]

[4]Denis,Jean-Noel;Greene,AndrewE.;Serra,A.Aarao;Luche,Marie-Jacqueline[JournalofOrganicChemistry,1986,vol.51,#1,p.46-50]

[5]Pavlakos,Ellas;Georglou,Thomas;Tofi,Maria;Montagnon,Tamsyn;Vassilikogiannakis,Georgios[OrganicLetters,2009,vol.11,#20,p.4556-4559]

[6]Fan,Shilu;Chen,Fei;Zhang,Xingang[AngewandteChemie-InternationalEdition,2011,vol.50,#26,p.5918-5923]

[7]Vasilikogiannaki,Eleni;Titilas,Ioannis;Vassilikogiannakis,Georgios;Stratakis,Manolis[ChemicalCommunications,2015,vol.51,#12,p.2384-2387]

[8]Takeuchi,Ryo;Kashio,Mikihiro[JournaloftheAmericanChemicalSociety,1998,vol.120,#34,p.8647-8655]

[9]Wagh,YogeshS.;Asao,Naoki[JournalofOrganicChemistry,2015,vol.80,#2,p.847-851]

[10]Liu,Lihua;Bao,Xifei;Xiao,Hua;Li,Junlan;Ye,Feifan;Wang,Chaoqin;Cai,Qinhua;Fan,Shilu[JournalofOrganicChemistry,2019,vol.84,#1,p.423-434]

[11]Davies,StephenG.;Fletcher,AiM.;Roberts,PaulM.;Thomson,JamesE.;Zammit,CharlotteM.[ChemicalCommunications,2013,vol.49,#63,p.7037-7039]

[12]Liang,Shengzong;Hammond,GeraldB.;Xu,Bo[ChemicalCommunications,2016,vol.52,#35,p.6013-6016]

[13]Zhao,Chuan-Qi;Chen,Yue-Gang;Qiu,Hui;Wei,Lei;Fang,Ping;Mei,Tian-Sheng[OrganicLetters,2019,vol.21,#5,p.1412-1416]

[14]Wang,Guang-Hui;Bin,Huai-Yu;Sun,Miao;Chen,Shu-Wei;Liu,Ji-Hong;Zhong,Chong-Min[Tetrahedron,2014,vol.70,#12,p.2175-2179]

[15]Fukuda,Tsutomu;Irie,Ryo;Katsuki,Tsutomu[Tetrahedron,1999,vol.55,#3,p.649-664]

[16]In,SuKim;Guang,RiDong;Young,HoonJung[JournalofOrganicChemistry,2007,vol.72,#14,p.5424-5426]

[17]Li,Shu-Shuang;Tao,Lei;Wang,Fu-Ze-Rong;Liu,Yong-Mei;Cao,Yong[AdvancedSynthesisandCatalysis,2016,vol.358,#9,p.1410-1416]

[18]Park,ByoungYong;Lim,Taeho;Han,MinSu[ChemicalCommunications,2021,vol.57,#56,p.6891-6894]

[19]Alker,David;Mageswaran,Sivapathasuntharam;Ollis,W.David;Shahriari-Zavareh,Hooshang[JournaloftheChemicalSociety.PerkintransactionsI,1990,#6,p.1631-1635]

[20]Charette;Molinaro;Brochu[JournaloftheAmericanChemicalSociety,2001,vol.123,#49,p.12168-12175]

[21]Locationinpatent:experimentalpartTang,Wanxia;Minato,Hiroshi;Ando,Mariko;Ando,Masayoshi[Heterocycles,2012,vol.85,#7,p.1697-1710]

[22]Cho,Hyunkyung;Shin,JaeEui;Lee,Seokwoo;Jeon,Hongjun;Park,Soojun;Kim,Sanghee[OrganicLetters,2018,vol.20,#19,p.6121-6125]

[23]Liu,Mingyu;Yang,Pusu;Karunananda,MalkanthiK.;Wang,Yanyan;Liu,Peng;Engle,KearyM.[JournaloftheAmericanChemicalSociety,2018,vol.140,#17,p.5805-5813]

[24]Murugesan,Kathiravan;Alshammari,AhmadS.;Sohail,Manzar;Beller,Matthias;Jagadeesh,RajenahallyV.[JournalofCatalysis,2019,vol.370,p.372-377]

[25]Takale,BalaramS.;Feng,Xiujuan;Lu,Ye;Bao,Ming;Jin,Tienan;Minato,Taketoshi;Yamamoto,Yoshinori[JournaloftheAmericanChemicalSociety,2016,vol.138,#32,p.10356-10364]

[26]Huple,DeepakB.;Mokar,BhanudasD.;Liu,Rai-Shung[AngewandteChemie-InternationalEdition,2015,vol.54,#49,p.14924-14928][Angew.Chem.,2016,vol.127,#49,p.15137-15141,5]

[27]Wissing,Maren;Niehues,Maximilian;Ravoo,BartJan;Studer,Armido[EuropeanJournalofOrganicChemistry,2018,vol.2018,#26,p.3403-3409]

[28]CurrentPatentAssignee:ZHENGZHOUUNIVERSITY-CN111099986,2020,ALocationinpatent:Paragraph0034;0273-0276

[29]Wang,Yong;Cao,Xinyi;Zhao,Leyao;Pi,Chao;Ji,Jingfei;Cui,Xiuling;Wu,Yangjie[AdvancedSynthesisandCatalysis,2020,vol.362,#19,p.4119-4129]

[30]DeJesúsCruz,Pedro;Crawford,EvanT.;Liu,Shubin;Johnson,JeffreyS.[JournaloftheAmericanChemicalSociety,2021,vol.143,#39,p.16264-16273]

[31]Theberge,CoryR.;Zercher,CharlesK.[TetrahedronLetters,1995,vol.36,#31,p.5495-5498]

[32]Campana,AraceliG.;Estevez,RosaE.;Fuentes,Noelia;Rubles,Rafael;Cuerva,JuanM.;Bunuel,Elena;Cardenas,Diego;Oltra,J.Enrique[OrganicLetters,2007,vol.9,#11,p.2195-2198]

[33]Heckenbichler,Kathrin;Schweiger,Anna;Brandner,LeaAlexandra;Binter,Alexandra;Toplak,Marina;Macheroux,Peter;Gruber,Karl;Breinbauer,Rolf[AngewandteChemie-InternationalEdition,2018,vol.57,#24,p.7240-7244][Angew.Chem.,2018,#130,p.7360-7364,5]

[34]Han,Xiaowei;Hu,Jiefeng;Chen,Cheng;Yuan,Yu;Shi,Zhuangzhi[ChemicalCommunications,2019,vol.55,#48,p.6922-6925]

[35]Smith,PeterA.S.;Chou,Shang-shingPeter[JournalofOrganicChemistry,1981,vol.46,#20,p.3970-3977]

[36]Echavarren,AntonioM.;Franchino,Allegra;Martí,Àlex[JournaloftheAmericanChemicalSociety,2022,vol.144,#8,p.3497-3509]

[37]Zhao,Yankai;Liu,Qiang;Li,Jing;Liu,Zhongquan;Zhou,Bo[Synlett,2010,#12,p.1870-1872]

[38]Reina,Antonio;Favier,Isabelle;Pradel,Christian;Gómez,Montserrat[AdvancedSynthesisandCatalysis,2018,vol.360,#18,p.3544-3552]

[39]Gredy[BulletindelaSocieteChimiquedeFrance,1936,vol.<5>3,p.1102][ComptesRendusHebdomadairesdesSeancesdel'AcademiedesSciences,1936,vol.202,p.322]

[40]Bourguel;Yvon[ComptesRendusHebdomadairesdesSeancesdel'AcademiedesSciences,1926,vol.182,p.224]

[41]Goering,HarlanL.;Kantner,StevenS.[JournalofOrganicChemistry,1983,vol.48,#5,p.721-724]

[42]Rideout,JanetL.;Krenitsky,ThomasA.;Chao,EstherY.;Elion,GertrudeB.;Williams,RaymondB.;Latter,VictoriaS.[JournalofMedicinalChemistry,1983,vol.26,#10,p.1489-1494]

[43]Kawamura,Yasufumi;Imai,Takuro;Hosokawa,Takahiro[Synlett,2006,#18,p.3110-3114]

[44]Garbaccio,RobertM.;Tasber,EdwardS.;Neilson,LouAnne;Coleman,PaulJ.;Fraley,MarkE.;Olson,Christy;Bergman,Jeff;Torrent,Maricel;Buser,CarolynA.;Rickert,Keith;Walsh,EileenS.;Hamilton,Kelly;Lobell,RobertB.;Tao,Weikang;South,VickiJ.;Diehl,RonaldE.;Davide,JosephP.;Yan,Youwei;Kuo,LawrenceC.;Li,Chunze;Prueksaritanont,Thomayant;Fernandez-Metzler,Carmen;Mahan,ElizabethA.;Slaughter,DonaldE.;Salata,JosephJ.;Kohl,NancyE.;Huber,HansE.;Hartman,GeorgeD.[BioorganicandMedicinalChemistryLetters,2007,vol.17,#20,p.5671-5676]

[45]Sarkar,AchintyaK[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1993,vol.32,#6,p.670-671]

[46]Sarkar,AchintyaK[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1993,vol.32,#6,p.670-671]

[47]Jiang,Tao;Huynh,Khoi;Livinghouse,Tom[Synlett,2013,vol.24,#2,p.193-196]

[48]Drost,RubenM.;Bouwens,Tessel;VanLeest,NicolaasP.;DeBruin,Bas;Elsevier,CornelisJ.[ACSCatalysis,2014,vol.4,#5,p.1349-1357]

[49]Itoh,Taisuke;Shimizu,Yohei;Kanai,Motomu[OrganicLetters,2014,vol.16,#10,p.2736-2739]

[50]Orr,David;Percy,JonathanM.;Tuttle,Tell;Kennedy,AlanR.;Harrison,ZoA.[Chemistry-AEuropeanJournal,2014,vol.20,#44,p.14305-14316]

[51]Soltanzadeh,Bardia;Jaganathan,Arvind;Staples,RichardJ.;Borhan,Babak[AngewandteChemie-InternationalEdition,2015,vol.54,#33,p.9517-9522][Angew.Chem.,2015,vol.127,p.9653-9658,6]

[52]Fu,Shaomin;Chen,Nan-Yu;Liu,Xufang;Shao,Zhihui;Luo,Shu-Ping;Liu,Qiang[JournaloftheAmericanChemicalSociety,2016,vol.138,#27,p.8588-8594]

[53]Qiu,Guanyinsheng;Mamboury,Mathias;Wang,Qian;Zhu,Jieping[AngewandteChemie-InternationalEdition,2016,vol.55,#49,p.15377-15381][Angew.Chem.,2016,vol.128,p.15603-15607,5]

[54]Chen,Caiyou;Huang,Yi;Zhang,Zongpeng;Dong,Xiu-Qin;Zhang,Xumu[ChemicalCommunications,2017,vol.53,#33,p.4612-4615]

[55]Xu,Bin;Tambar,UttamK.[AngewandteChemie-InternationalEdition,2017,vol.56,#33,p.9868-9871][Angew.Chem.,2017,vol.129,p.10000-10003,4]

[56]Ji,Guijie;Duan,Yanan;Zhang,Shaochun;Fei,Benhua;Chen,Xiufang;Yang,Yong[ChemSusChem,2017,vol.10,#17,p.3427-3434]

[57]Landge,VinodG.;Pitchaimani,Jayaraman;Midya,SibaP.;Subaramanian,Murugan;Madhu,Vedichi;Balaraman,Ekambaram[Catalysisscienceandtechnology,2018,vol.8,#2,p.428-433]

[58]Takada,Yuki;Caner,Joaquim;Kaliyamoorthy,Selvam;Naka,Hiroshi;Saito,Susumu[Chemistry-AEuropeanJournal,2017,vol.23,#71,p.18025-18032]

[59]CurrentPatentAssignee:ONOPHARMACEUTICALCOLTD-EP3409658,2018,A1Locationinpatent:Paragraph0142

[60]Mizuno,Takahiro;Murai,Toshiaki;Shibahara,Fumitoshi;Shibata,Yoshifuru[BulletinoftheChemicalSocietyofJapan,2020,vol.93,#3,p.332-337]

[61]Awasthi,MahendraK.;Barman,SudiptaRoy;Behrens,Silke;Rai,RohitK.;Singh,SanjayK.;Singh,VipinK.[Catalysisscienceandtechnology,2020,vol.10,#15,p.4968-4980]

[62]Bernard-Gauthier,Vadim;Mossine,AndrewV.;Knight,Ashley;Patnaik,Debasis;Zhao,Wen-Ning;Cheng,Chialin;Krishnan,HemaS.;Xuan,LuciusL.;Chindavong,PeterS.;Reis,SuryaA.;Chen,JinshanMichael;Shao,Xia;Stauff,Jenelle;Arteaga,Janna;Sherman,Phillip;Salem,Nicolas;Bonsall,David;Amaral,Brenda;Varlow,Cassis;Wells,Lisa;Martarello,Laurent;Patel,Shil;Liang,StevenH.;Kurumbail,RaviG.;Haggarty,StephenJ.;Scott,PeterJ.H.;Vasdev,Neil[JournalofMedicinalChemistry,2019,vol.62,#21,p.9600-9617]

[63]Saito,Hiroki;Kato,Ranmaru;Ikeuchi,Kazutada;Suzuki,Takahiro;Tanino,Keiji[OrganicLetters,2021,vol.23,#24,p.9606-9610]

[1]PhosphorusandSulfurandtheRelatedElements,1983,vol.18,p.187-190

[2]PhosphorusandSulfurandtheRelatedElements,1983,vol.18,p.187-190

[1]ChemistryofNaturalCompounds,1982,vol.18,p.685-688    KhimiyaPrirodnykhSoedinenii,1982,vol.18,p.723-727

[1]Mizugaki,Tomoo;Murata,Makoto;Fukubayashi,Sayaka;Mitsudome,Takato;Jitsukawa,Koichiro;Kaneda,Kiyotomi[ChemicalCommunications,2008,#2,p.241-243]

[2]DeLosBernardos,MiriamDíaz;Pérez-Rodríguez,Sara;Gual,Aitor;Claver,Carmen;Godard,Cyril[ChemicalCommunications,2017,vol.53,#56,p.7894-7897]

[3]Liguori,Francesca;Barbaro,Pierluigi[JournalofCatalysis,2014,vol.311,p.212-220]

[4]Nishio,Ryo;Sugiura,Masaharu;Kobayashi,Shu[OrganicandBiomolecularChemistry,2006,vol.4,#6,p.992-995]

[5]Montiel,Laura;Delgado,JorgeA.;Novell,Marta;Andrade,FranciscoJ.;Claver,Carmen;Blondeau,Pascal;Godard,Cyril[ChemCatChem,2016,vol.8,#19,p.3041-3044]

[1]ChemistryofNaturalCompounds,1982,vol.18,p.685-688    KhimiyaPrirodnykhSoedinenii,1982,vol.18,p.723-727

Literature

Title: Synthesis and biological evaluation of novel 2-(1H-imidazol-4-yl)cyclopropane carboxylic acids: key intermediates for H3 histamine receptor ligands.

Journal: Bioorganic & medicinal chemistry letters 20021216

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Tags:4510-34-3 Molecular Formula|4510-34-3 MDL|4510-34-3 SMILES|4510-34-3 (Z)-3-Phenyl-2-propen-1-ol