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4551-72-8,MFCD00273121
Catalog No.:AA00DA9C

4551-72-8 | 1H-Pyrrole-2-carboxamide

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250mg
95%
in stock  
$53.00   $37.00
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1g
97%
in stock  
$128.00   $90.00
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5g
97%
in stock  
$411.00   $288.00
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10g
97%
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$710.00   $497.00
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25g
97%
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$1,407.00   $985.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DA9C
Chemical Name:
1H-Pyrrole-2-carboxamide
CAS Number:
4551-72-8
Molecular Formula:
C5H6N2O
Molecular Weight:
110.1139
MDL Number:
MFCD00273121
SMILES:
NC(=O)c1ccc[nH]1
Properties
Computed Properties
 
Complexity:
103  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
0.2  

Downstream Synthesis Route

[1]ChemischeBerichte,1911,vol.44,p.3168

[1]GazzettaChimicaItaliana,1912,vol.42II,p.255

[1]RocznikiChemii,1951,vol.25,p.35,41    Chem.Abstr.,1953,p.10483

[1]JustusLiebigsAnnalenderChemie,1954,vol.589,p.174

[1]JustusLiebigsAnnalenderChemie,1860,vol.116,p.261

Literature

Title: The trifluoromethyl transformation synthesis, crystal structure and insecticidal activities of novel 2-pyrrolecarboxamide and 2-pyrrolecarboxlate.

Journal: Bioorganic & medicinal chemistry letters 20121115

Title: A sweet origin for the key congocidine precursor 4-acetamidopyrrole-2-carboxylate.

Journal: Angewandte Chemie (International ed. in English) 20120723

Title: The discovery and initial optimisation of pyrrole-2-carboxamides as inhibitors of p38alpha MAP kinase.

Journal: Bioorganic & medicinal chemistry letters 20100701

Title: Visual responses in mice lacking critical components of all known retinal phototransduction cascades.

Journal: PloS one 20100101

Title: Synthesis, Binding and Fluorescence Studies of Bis-2-amidopyrrole Receptors for Bis-carboxylate Anions.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

Journal: The Journal of pharmacology and experimental therapeutics 20070901

Title: Novel inhibitors of VEGF receptors-1 and -2 based on azole-5-carboxamide templates.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Heteronuclear intermolecular resonance-assisted hydrogen bonds. The structure of pyrrole-2-carboxamide (PyCa).

Journal: The journal of physical chemistry. B 20060330

Title: Solution-phase synthesis of a tricyclic pyrrole-2-carboxamide discovery library applying a stetter-Paal-Knorr reaction sequence.

Journal: Journal of combinatorial chemistry 20060101

Title: Novel non-steroidal/non-anilide type androgen antagonists: discovery of 4-substituted pyrrole-2-carboxamides as a new scaffold for androgen receptor ligands.

Journal: Bioorganic & medicinal chemistry 20050415

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SDS
Tags:4551-72-8 Molecular Formula|4551-72-8 MDL|4551-72-8 SMILES|4551-72-8 1H-Pyrrole-2-carboxamide