Home Amines 455264-30-9
455264-30-9,MFCD18207040
Catalog No.:AA00DAZI

455264-30-9 | (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
99%
1 week  
$1,130.00   $791.00
- +
25mg
99%
1 week  
$2,035.00   $1,424.00
- +
50mg
99%
1 week  
$3,225.00   $2,258.00
- +
100mg
99%
1 week  
$5,130.00   $3,591.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DAZI
Chemical Name:
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
CAS Number:
455264-30-9
Molecular Formula:
C28H29BrN4O3
Molecular Weight:
549.4589
MDL Number:
MFCD18207040
SMILES:
CCOC(=O)[C@@H](NC1=C(Br)C(=O)C21CCCCC2)Cc1ccc(cc1)Nc1nccc2c1cncc2
Properties

Downstream Synthesis Route
69042-30-4   
3-(4-amino-phenyl)-2(S)-(2-bromo-3-oxo-spiro3.5non-1-en-1-ylamino)propionicacidethylester 
  455264-30-9 

[1]Patent:WO2004/7428,2004,A1.Locationinpatent:Page56-57

Literature

Title: Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91.

Title: Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases? Drug Discov Today. 2007 Jul;12(13-14):569-76.

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Tags:455264-30-9 Molecular Formula|455264-30-9 MDL|455264-30-9 SMILES|455264-30-9 (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate