459856-18-9,MFCD22628864
Catalog No.:AA00DJML

459856-18-9 | Pexacerfont

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$53.00   $37.00
- +
5mg
98%
in stock  
$138.00   $97.00
- +
10mg
98%
in stock  
$198.00   $139.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DJML
Chemical Name:
Pexacerfont
CAS Number:
459856-18-9
Molecular Formula:
C18H24N6O
Molecular Weight:
340.4228
MDL Number:
MFCD22628864
SMILES:
CC[C@H](Nc1nc(C)nc2n1nc(c2c1ccc(nc1C)OC)C)C
Properties

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartBroxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

[2]Locationinpatent:experimentalpartGilligan,PaulJ.;Clarke,Todd;He,Liqi;Lelas,Snjezana;Li,Yu-Wen;Heman,Karen;Fitzgerald,Lawrence;Miller,Keith;Zhang,Ge;Marshall,Anne;Krause,Carol;McElroy,JohnF.;Ward,Kathyrn;Zeller,Kim;Wong,Harvey;Bai,Steven;Saye,Joanne;Grossman,Scott;Zaczek,Robert;Arneric,StephenP.;Hartig,Paul;Robertson,David;Trainor,George[JournalofMedicinalChemistry,2009,vol.52,#9,p.3084-3092]

[1]Broxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

[1]Broxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

[1]Broxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

Literature

Title: Zhou L, et al. In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist. Drug Metab Dispos. 2012 Jun;40(6):1093-103.

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Tags:459856-18-9 Molecular Formula|459856-18-9 MDL|459856-18-9 SMILES|459856-18-9 Pexacerfont
Catalog No.: AA00DJML
459856-18-9,MFCD22628864
459856-18-9 | Pexacerfont
Pack Size: 1mg
Purity: ≥98%
in stock
$53.00 $37.00
Pack Size: 5mg
Purity: 98%
in stock
$138.00 $97.00
Pack Size: 10mg
Purity: 98%
in stock
$198.00 $139.00
Quantity
- +
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bulk Quotation Request
Technical Information
Catalog Number: AA00DJML
Chemical Name: Pexacerfont
CAS Number: 459856-18-9
Molecular Formula: C18H24N6O
Molecular Weight: 340.4228
MDL Number: MFCD22628864
SMILES: CC[C@H](Nc1nc(C)nc2n1nc(c2c1ccc(nc1C)OC)C)C
Properties
Downstream Synthesis Route
13250-12-9    459856-19-0    459856-18-9 

[1]Locationinpatent:experimentalpartBroxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

[2]Locationinpatent:experimentalpartGilligan,PaulJ.;Clarke,Todd;He,Liqi;Lelas,Snjezana;Li,Yu-Wen;Heman,Karen;Fitzgerald,Lawrence;Miller,Keith;Zhang,Ge;Marshall,Anne;Krause,Carol;McElroy,JohnF.;Ward,Kathyrn;Zeller,Kim;Wong,Harvey;Bai,Steven;Saye,Joanne;Grossman,Scott;Zaczek,Robert;Arneric,StephenP.;Hartig,Paul;Robertson,David;Trainor,George[JournalofMedicinalChemistry,2009,vol.52,#9,p.3084-3092]

853569-73-0    459856-18-9 

[1]Broxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

1266353-39-2    459856-18-9 

[1]Broxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

1266353-36-9    459856-18-9 

[1]Broxer,Sevrine;Fitzgerald,MonicaA.;Sfouggatakis,Chris;Defreese,JessicaL.;Barlow,Evan;Powers,GeraldL.;Peddicord,Michael;Su,Bao-Ning;Tai-Yuen,Yue;Pathirana,Charles;Sherbine,JamesP.[OrganicProcessResearchandDevelopment,2011,vol.15,#2,p.343-352]

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