Catalog No.:AA00DJMM

461443-59-4 | Aplaviroc

Name: Name:Aplaviroc
Brand: AABLOCKS
SKU: AA00DJMM
Rating: 90 (10 reviews)

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA00DJMM

Chemical Name:

Aplaviroc

CAS Number:

461443-59-4

Molecular Formula:

C33H43N3O6

Molecular Weight:

577.7110

MDL Number:

MFCD22200785

SMILES:

CCCCN1C(=O)C(NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)C(C5CCCCC5)O

Properties

Literature

Title: Maeda K, et al. Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro. J Virol. 2004 Aug;78(16):8654-62.

Title: Hirotomo Nakata, et al. Potent anti-R5 human immunodeficiency virus type 1 effects of a CCR5 antagonist, AK602/ONO4128/GW873140, in a novel human peripheral blood mononuclear cell nonobese diabetic-SCID, interleukin-2 receptor gamma-chain-knocked-out AIDS mouse model. Virol. 2005 Feb;79(4):2087-96.

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