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462-88-4,MFCD00043023
Catalog No.:AA003JUE

462-88-4 | 3-Ureidopropionic acid

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100mg
98.0% (T)
in stock  
$84.00   $59.00
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250mg
98.0% (T)
in stock  
$107.00   $75.00
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1g
98.0% (T)
in stock  
$209.00   $147.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003JUE
Chemical Name:
3-Ureidopropionic acid
CAS Number:
462-88-4
Molecular Formula:
C4H8N2O3
Molecular Weight:
132.1179
MDL Number:
MFCD00043023
SMILES:
OC(=O)CCNC(=O)N
NSC Number:
65768
Properties
Properties
 
BP:
324.8°C at 760 mmHg  
Form:
Solid  
MP:
166-168°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
123  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
-1.5  

Literature

Title: An effective assessment of simvastatin-induced toxicity with NMR-based metabonomics approach.

Journal: PloS one 20110101

Title: Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni.

Journal: Parasites & vectors 20110101

Title: The 3-ureidopropionase of Caenorhabditis elegans, an enzyme involved in pyrimidine degradation.

Journal: The FEBS journal 20101001

Title: Metabolic changes reveal the development of schistosomiasis in mice.

Journal: PLoS neglected tropical diseases 20100801

Title: Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents.

Journal: Journal of proteome research 20100507

Title: Discovery of safety biomarkers for atorvastatin in rat urine using mass spectrometry based metabolomics combined with global and targeted approach.

Journal: Analytica chimica acta 20100219

Title: Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model.

Journal: Analytical chemistry 20100101

Title: Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression.

Journal: Malaria journal 20100101

Title: Five cases of beta-ureidopropionase deficiency detected by GC/MS analysis of urine metabolome.

Journal: Journal of mass spectrometry : JMS 20090201

Title: Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.

Journal: PLoS neglected tropical diseases 20080701

Title: A recruited protease is involved in catabolism of pyrimidines.

Journal: Journal of molecular biology 20080530

Title: The crystal structure of beta-alanine synthase from Drosophila melanogaster reveals a homooctameric helical turn-like assembly.

Journal: Journal of molecular biology 20080411

Title: Amidohydrolases of the reductive pyrimidine catabolic pathway purification, characterization, structure, reaction mechanisms and enzyme deficiency.

Journal: Biochimica et biophysica acta 20080301

Title: Beta-ureidopropionase deficiency presenting with congenital anomalies of the urogenital and colorectal systems.

Journal: Molecular genetics and metabolism 20080201

Title: Crystal structures of yeast beta-alanine synthase complexes reveal the mode of substrate binding and large scale domain closure movements.

Journal: The Journal of biological chemistry 20071207

Title: Clinical, biochemical and genetic findings in two siblings with a dihydropyrimidinase deficiency.

Journal: Molecular genetics and metabolism 20070601

Title: [Cloning, expression and purification of D-carbamoylase from Sinorhizobium morelens S-5].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20060801

Title: Liquid chromatography-tandem mass spectrometric assay for the analysis of uracil, 5,6-dihydrouracil and beta-ureidopropionic acid in urine for the measurement of the activities of the pyrimidine catabolic enzymes.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724

Title: The crystal structures of dihydropyrimidinases reaffirm the close relationship between cyclic amidohydrolases and explain their substrate specificity.

Journal: The Journal of biological chemistry 20060512

Title: Physiologically based pharmacokinetic modelling of the three-step metabolism of pyrimidine using C-uracil as an in vivo probe.

Journal: British journal of clinical pharmacology 20051201

Title: Purification and properties of beta-alanine synthase from calf liver.

Journal: Protein and peptide letters 20050101

Title: Molecular cloning and biochemical characterization of L-N-carbamoylase from Sinorhizobium meliloti CECT4114.

Journal: Journal of molecular microbiology and biotechnology 20050101

Title: Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Journal of inherited metabolic disease 20050101

Title: beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities.

Journal: Human molecular genetics 20041115

Title: Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705

Title: Crystallization and preliminary X-ray diffraction analysis of thermophilic imidase from pig liver.

Journal: Acta crystallographica. Section D, Biological crystallography 20030501

Title: Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.

Journal: Planta 20020901

Title: Screening and diagnosis of beta-ureidopropionase deficiency by gas chromatographic/mass spectrometric analysis of urine.

Journal: Journal of mass spectrometry : JMS 20020901

Title: Development and characterization of a monoclonal antibody with cross-reactivity towards uracil and thymine, and its potential use in screening patients treated with 5-fluorouracil for possible risks.

Journal: Clinica chimica acta; international journal of clinical chemistry 20020801

Title: Detection of beta-ureidopropionase deficiency with HPLC-electrospray tandem mass spectrometry and confirmation of the defect at the enzyme level.

Journal: Journal of inherited metabolic disease 20011201

Title: 3-Ureidopropionate contributes to the neuropathology of 3-ureidopropionase deficiency and severe propionic aciduria: a hypothesis.

Journal: Journal of neuroscience research 20011115

Title: beta-Ureidopropionase deficiency: a novel inborn error of metabolism discovered using NMR spectroscopy on urine.

Journal: Magnetic resonance in medicine 20011101

Title: Eukaryotic beta-alanine synthases are functionally related but have a high degree of structural diversity.

Journal: Genetics 20010701

Title: Synthesis and biological activity of analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid: discovery of a novel aminoguanidinoacetic acid antidiabetic agent.

Journal: Journal of medicinal chemistry 20010412

Title: Expression and properties of human liver beta-ureidopropionase.

Journal: Journal of nutritional science and vitaminology 20010401

Title: Characterization of plant beta-ureidopropionase and functional overexpression in Escherichia coli.

Journal: Plant physiology 20010201

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