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4670-05-7,MFCD03427500
Catalog No.:AA003UOW

4670-05-7 | Theaflavin

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1mg
≥98%
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$52.00   $36.00
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2mg
98%
in stock  
$67.00   $47.00
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5mg
98%
in stock  
$126.00   $89.00
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10mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003UOW
Chemical Name:
Theaflavin
CAS Number:
4670-05-7
Molecular Formula:
C29H24O12
Molecular Weight:
564.4937
MDL Number:
MFCD03427500
SMILES:
Oc1cc2O[C@@H]([C@@H](Cc2c(c1)O)O)c1cc2c(cc(c(c2c(=O)c(c1)O)O)O)[C@H]1Oc2cc(O)cc(c2C[C@H]1O)O
Properties
Properties
 
BP:
1003.9°C at 760mmHg  
Form:
Solid  
MP:
237-240℃ (dec.)(Solv: water (7732-18-5))  
Storage:
Light sensitive;Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
1060  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
9  
Rotatable Bond Count:
2  
XLogP3:
2.4  

Literature

Title: Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice.

Journal: Toxicology and applied pharmacology 20160601

Title: Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans.

Journal: Journal of microbiology and biotechnology 20130928

Title: Synthesis of PLGA nanoparticles of tea polyphenols and their strong in vivo protective effect against chemically induced DNA damage.

Journal: International journal of nanomedicine 20130101

Title: Intake estimation of total and individual flavan-3-ols, proanthocyanidins and theaflavins, their food sources and determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

Journal: The British journal of nutrition 20120928

Title: Theaflavin ameliorates behavioral deficits, biochemical indices and monoamine transporters expression against subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease.

Journal: Neuroscience 20120830

Title: Theaflavins inhibit the ATP synthase and the respiratory chain without increasing superoxide production.

Journal: The Journal of nutritional biochemistry 20120801

Title: Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: possible involvement of Hsp90, Wnt/β-catenin signaling and FOXO1.

Journal: The FEBS journal 20120801

Title: In vitro anti-influenza virus and anti-inflammatory activities of theaflavin derivatives.

Journal: Antiviral research 20120601

Title: [Adsorption dynamics study on interactions of pigments and human whole saliva].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20120601

Title: Protective effect of theaflavins on homocysteine-induced injury in HUVEC cells in vitro.

Journal: Journal of cardiovascular pharmacology 20120501

Title: Effects of green tea or Sasa quelpaertensis bamboo leaves on plasma and liver lipids, erythrocyte Na efflux, and platelet aggregation in ovariectomized rats.

Journal: Nutrition research and practice 20120401

Title: A natural theaflavins preparation inhibits HIV-1 infection by targeting the entry step: potential applications for preventing HIV-1 infection.

Journal: Fitoterapia 20120301

Title: Black tea polyphenols inhibit tumor proteasome activity.

Journal: In vivo (Athens, Greece) 20120301

Title: Protective effect of theaflavins on neuron against 6-hydroxydopamine-induced apoptosis in SH-SY5Y cells.

Journal: Journal of clinical biochemistry and nutrition 20120301

Title: Theaflavins extracted from black tea inhibit airway mucous hypersecretion induced by cigarette smoke in rats.

Journal: Inflammation 20120201

Title: Dietary flavan-3-ols intake and metabolic syndrome risk in Korean adults.

Journal: Nutrition research and practice 20120201

Title: Theaflavin, a black tea polyphenol, protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease.

Journal: Brain research 20120118

Title: Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model.

Journal: Biochemical and biophysical research communications 20120106

Title: Impact of nanotechnology in cancer: emphasis on nanochemoprevention.

Journal: International journal of nanomedicine 20120101

Title: Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate.

Journal: Frontiers in microbiology 20120101

Title: Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly?

Journal: Frontiers in pharmacology 20120101

Title: Black tea theaflavins inhibit formation of toxic amyloid-β and α-synuclein fibrils.

Journal: Biochemistry 20111213

Title: Neuroprotective effects of white tea against oxidative stress-induced toxicity in striatal cells.

Journal: Neurotoxicity research 20111101

Title: Antibacterial effects of theaflavin and synergy with epicatechin against clinical isolates of Acinetobacter baumannii and Stenotrophomonas maltophilia.

Journal: International journal of antimicrobial agents 20111101

Title: Structural identification of mouse fecal metabolites of theaflavin 3,3'-digallate using liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. A 20111014

Title: Effects of enzymatic action on the formation of theabrownin during solid state fermentation of Pu-erh tea.

Journal: Journal of the science of food and agriculture 20111001

Title: Development and evaluation of a spiral tube column for counter-current chromatography.

Journal: Journal of separation science 20111001

Title: Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses.

Journal: Journal of Zhejiang University. Science. B 20110901

Title: The chemistry and biotransformation of tea constituents.

Journal: Pharmacological research 20110801

Title: Theaflavin Inhibits LPS-Induced IL-6, MCP-1, and ICAM-1 Expression in Bone Marrow-Derived Macrophages Through the Blockade of NF-κB and MAPK Signaling Pathways.

Journal: Chonnam medical journal 20110801

Title: ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat.

Journal: The journal of physiological sciences : JPS 20110701

Title: Black tea and theaflavins suppress various inflammatory modulators and i-NOS mediated nitric oxide synthesis during gastric ulcer healing.

Journal: Free radical research 20110701

Title: Black tea polyphenol inhibits CXCL10 production in oncostatin M-stimulated human gingival fibroblasts.

Journal: International immunopharmacology 20110601

Title: Characterization of tea cultivated at four different altitudes using 1H NMR analysis coupled with multivariate statistics.

Journal: Journal of agricultural and food chemistry 20110525

Title: Black tea polyphenol theaflavin suppresses LPS-induced ICAM-1 and VCAM-1 expression via blockage of NF-κB and JNK activation in intestinal epithelial cells.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110501

Title: Molecular binding of black tea theaflavins to biological membranes: relationship to bioactivities.

Journal: Journal of agricultural and food chemistry 20110427

Title: Diverse inhibition of plasminogen activator inhibitor type 1 by theaflavins of black tea.

Journal: International journal of molecular medicine 20110401

Title: Theaflavins depolymerize microtubule network through tubulin binding and cause apoptosis of cervical carcinoma HeLa cells.

Journal: Journal of agricultural and food chemistry 20110309

Title: Affinity interactions between natural pigments and human whole saliva.

Journal: Archives of oral biology 20110301

Title: Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo.

Journal: Molecular nutrition & food research 20110201

Title: [Adsorption kinetic study of the interaction between human salivary alpha-amylase and the polyphenoles from the black/green tea].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20110201

Title: Targeting PML-RARα and Oncogenic Signaling Pathways by Chinese Herbal Mixture Tien-Hsien Liquid in Acute Promyelocytic Leukemia NB4 Cells.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.

Journal: International journal of molecular sciences 20110101

Title: The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols.

Journal: BMC biochemistry 20110101

Title: Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation.

Journal: Journal of neuroinflammation 20110101

Title: Changes of constituents and activity to apoptosis and cell cycle during fermentation of tea.

Journal: International journal of molecular sciences 20110101

Title: Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals.

Journal: Journal of toxicology 20110101

Title: Tea polyphenols induce apoptosis through mitochondrial pathway and by inhibiting nuclear factor-kappaB and Akt activation in human cervical cancer cells.

Journal: Oncology research 20110101

Title: Variations of antioxidant properties and NO scavenging abilities during fermentation of tea.

Journal: International journal of molecular sciences 20110101

Title: Comparative antimutagenic and anticancer activity of three fractions of black tea polyphenols thearubigins.

Journal: Nutrition and cancer 20110101

Title: Biomedical potential of silver nanoparticles synthesized from calli cells of Citrullus colocynthis (L.) Schrad.

Journal: Journal of nanobiotechnology 20110101

Title: Black tea extract prevents lipopolysaccharide-induced NF-κB signaling and attenuates dextran sulfate sodium-induced experimental colitis.

Journal: BMC complementary and alternative medicine 20110101

Title: Pu-Erh tea and GABA attenuates oxidative stress in kainic acid-induced status epilepticus.

Journal: Journal of biomedical science 20110101

Title: Antioxidant and antibacterial properties of green, black, and herbal teas of Camellia sinensis.

Journal: Pharmacognosy research 20110101

Title: Chemistry and biochemistry of dietary polyphenols.

Journal: Nutrients 20101201

Title: Oxidative cascade reactions yielding polyhydroxy-theaflavins and theacitrins in the formation of black tea thearubigins: evidence by tandem LC-MS.

Journal: Food & function 20101101

Title: Preventive effects of black tea theaflavins against mouse type IV allergy.

Journal: Journal of the science of food and agriculture 20100901

Title: Black-tea polyphenols decrease micellar solubility of cholesterol in vitro and intestinal absorption of cholesterol in rats.

Journal: Journal of agricultural and food chemistry 20100811

Title: Substrate specificity of the mitochondrial thioredoxin reductase of the parasitic nematode Haemonchus contortus.

Journal: Parasitology research 20100701

Title: Black tea polyphenols-mediated in vivo cellular responses during carcinogenesis.

Journal: Mini reviews in medicinal chemistry 20100601

Title: Synergistic effects of tea polyphenols and ascorbic acid on human lung adenocarcinoma SPC-A-1 cells.

Journal: Journal of Zhejiang University. Science. B 20100601

Title: Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100401

Title: Purified black tea theaflavins and theaflavins/catechin supplements did not affect serum lipids in healthy individuals with mildly to moderately elevated cholesterol concentrations.

Journal: European journal of nutrition 20100201

Title: Theaflavins target Fas/caspase-8 and Akt/pBad pathways to induce apoptosis in p53-mutated human breast cancer cells.

Journal: Carcinogenesis 20100201

Title: Theaflavins retard human breast cancer cell migration by inhibiting NF-kappaB via p53-ROS cross-talk.

Journal: FEBS letters 20100104

Title: Reaction of the black tea pigment theaflavin during enzymatic oxidation of tea catechins.

Journal: Journal of natural products 20100101

Title: The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide.

Journal: Nutrition journal 20100101

Title: Chemistry of secondary polyphenols produced during processing of tea and selected foods.

Journal: International journal of molecular sciences 20100101

Title: The effects of theaflavin-enriched black tea extract on muscle soreness, oxidative stress, inflammation, and endocrine responses to acute anaerobic interval training: a randomized, double-blind, crossover study.

Journal: Journal of the International Society of Sports Nutrition 20100101

Title: Impact of dietary polyphenols on carbohydrate metabolism.

Journal: International journal of molecular sciences 20100101

Title: Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20100101

Title: Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I.

Journal: PloS one 20100101

Title: Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells.

Journal: Molecular cancer 20100101

Title: Novel screening method for potential skin-whitening compounds by a luciferase reporter assay.

Journal: Bioscience, biotechnology, and biochemistry 20100101

Title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.

Journal: Journal of ethnobiology and ethnomedicine 20100101

Title: Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model.

Journal: Mediators of inflammation 20100101

Title: The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

Title: Alternative perspectives: how chinese medicine understands hypercholesterolemia.

Journal: Cholesterol 20100101

Title: The inhibitory effect of Camellia sinensis extracts against the neuromuscular blockade of Crotalus durissus terrificus venom.

Journal: Journal of venom research 20100101

Title: 1,1-Diphenyl-2-picrylhydrazyl radical and superoxide anion scavenging activity of Rhizophora mangle (L.) bark.

Journal: Pharmacognosy research 20100101

Title: Assessment of Immunomodulatory Activity of Euphorbia hirta L.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Role of oxidation-triggered activation of JNK and p38 MAPK in black tea polyphenols induced apoptotic death of A375 cells.

Journal: Cancer science 20091001

Title: Layer-by-Layer-Coated Gelatin Nanoparticles as a Vehicle for Delivery of Natural Polyphenols.

Journal: ACS nano 20090728

Title: Increase of theaflavin gallates and thearubigins by acceleration of catechin oxidation in a new fermented tea product obtained by the tea-rolling processing of loquat ( Eriobotrya japonica ) and green tea leaves.

Journal: Journal of agricultural and food chemistry 20090708

Title: Effects of theaflavins on melanin biosynthesis in mouse b16 melanoma cells.

Journal: Bioscience, biotechnology, and biochemistry 20090601

Title: Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1.

Journal: The Journal of nutritional biochemistry 20090501

Title: Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticals.

Journal: In vitro cellular & developmental biology. Animal 20090101

Title: The protective effects of green tea extract against L-arginine toxicity to cultured human mesangial cells.

Journal: Journal of Korean medical science 20090101

Title: Antifungal activity of black tea polyphenols (catechins and theaflavins) against Candida species.

Journal: Chemotherapy 20090101

Title: [Effects of theaflavins on the signal transduction pathway of epidermal growth factor receptor in airway mucous hypersecretion].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090101

Title: Effects of apple juice on risk factors of lipid profile, inflammation and coagulation, endothelial markers and atherosclerotic lesions in high cholesterolemic rabbits.

Journal: Lipids in health and disease 20090101

Title: Tumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins.

Journal: PloS one 20090101

Title: Polyphenols action against oxidative stress formation in endothelial cells.

Journal: Acta poloniae pharmaceutica 20090101

Title: Increased responsiveness of human coronary artery endothelial cells in inflammation and coagulation.

Journal: Mediators of inflammation 20090101

Title: Plant polyphenols as dietary antioxidants in human health and disease.

Journal: Oxidative medicine and cellular longevity 20090101

Title: PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate.

Journal: European journal of pharmacology 20081228

Title: Theaflavins from black tea, especially theaflavin-3-gallate, reduce the incorporation of cholesterol into mixed micelles.

Journal: Journal of agricultural and food chemistry 20081224

Title: New phenolic components and chromatographic profiles of green and fermented teas.

Journal: Journal of agricultural and food chemistry 20080910

Title: Radical-scavenging abilities and antioxidant properties of theaflavins and their gallate esters in H2O2-mediated oxidative damage system in the HPF-1 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080801

Title: Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant properties.

Journal: Basic & clinical pharmacology & toxicology 20080701

Title: Inhibitory mechanisms of flavonoids on insulin-stimulated glucose uptake in MC3T3-G2/PA6 adipose cells.

Journal: Biological & pharmaceutical bulletin 20080701

Title: Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20080601

Title: Preparative isolation and purification of theaflavins and catechins by high-speed countercurrent chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080515

Title: Polymer-like polyphenols of black tea and their lipase and amylase inhibitory activities.

Journal: Chemical & pharmaceutical bulletin 20080301

Title: Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate.

Journal: American journal of physiology. Heart and circulatory physiology 20080101

Title: Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a.

Journal: Aging cell 20080101

Title: Combination of HSCCC and Sephadex LH-20 methods An approach to isolation and purification of the main individual theaflavins from black tea.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080101

Title: Monitoring the binding processes of black tea thearubigin to the bovine serum albumin surface using quartz crystal microbalance with dissipation monitoring.

Journal: Journal of agricultural and food chemistry 20071212

Title: Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3.

Journal: Biopharmaceutics & drug disposition 20071201

Title: Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells.

Journal: Journal of lipid research 20071101

Title: Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells.

Journal: Life sciences 20071013

Title: Determination of theaflavins including methylated theaflavins in black tea leaves by solid-phase extraction and HPLC analysis.

Journal: Journal of agricultural and food chemistry 20070905

Title: Inhibition of 17alpha-hydroxylase/C17,20-lyase (CYP17) from rat testis by green tea catechins and black tea theaflavins.

Journal: Bioscience, biotechnology, and biochemistry 20070901

Title: Inhibitory activities of dietary phenolic compounds on heterocyclic amine formation in both chemical model system and beef patties.

Journal: Molecular nutrition & food research 20070801

Title: Effects of infusion time and addition of milk on content and absorption of polyphenols from black tea.

Journal: Journal of agricultural and food chemistry 20070613

Title: Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kappa B and mitogen-activated protein kinases pathways.

Journal: Life sciences 20070516

Title: Breast cancer prevention by green tea catechins and black tea theaflavins in the C3(1) SV40 T,t antigen transgenic mouse model is accompanied by increased apoptosis and a decrease in oxidative DNA adducts.

Journal: Journal of agricultural and food chemistry 20070502

Title: Structure-activity relationships of tea compounds against human cancer cells.

Journal: Journal of agricultural and food chemistry 20070124

Title: Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling.

Journal: Toxicology and applied pharmacology 20070115

Title: alpha-Glucosidase inhibitory profile of catechins and theaflavins.

Journal: Journal of agricultural and food chemistry 20070110

Title: Comparison of plants used for skin and stomach problems in Trinidad and Tobago with Asian ethnomedicine.

Journal: Journal of ethnobiology and ethnomedicine 20070101

Title: Modulation of the oxidative stress and nuclear factor kappaB activation by theaflavin 3,3'-gallate in the rats exposed to cerebral ischemia-reperfusion.

Journal: Folia biologica 20070101

Title: Effects of a combination of thyme and oregano essential oils on TNBS-induced colitis in mice.

Journal: Mediators of inflammation 20070101

Title: Trapping reactions of reactive carbonyl species with tea polyphenols in simulated physiological conditions.

Journal: Molecular nutrition & food research 20061201

Title: High-throughput analysis of catechins and theaflavins by high performance liquid chromatography with diode array detection.

Journal: Journal of chromatography. A 20061103

Title: [Simultaneous analysis of theaflavins and catechins by capillary electrophoresis].

Journal: Se pu = Chinese journal of chromatography 20061101

Title: In vitro cytotoxicity of a theaflavin mixture from black tea to malignant, immortalized, and normal cells from the human oral cavity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060801

Title: Anticlastogenic effects of black tea polyphenols theaflavins and thearubigins in human lymphocytes in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060801

Title: Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20060801

Title: Molecular and cellular targets.

Journal: Molecular carcinogenesis 20060601

Title: Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines.

Journal: Evidence-based complementary and alternative medicine : eCAM 20060601

Title: Analytical separation of tea catechins and food-related polyphenols by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20060421

Title: Potent inhibitory effects of black tea theaflavins on off-odor formation from citral.

Journal: Journal of agricultural and food chemistry 20060419

Title: Inhibition of CWR22Rnu1 tumor growth and PSA secretion in athymic nude mice by green and black teas.

Journal: Carcinogenesis 20060401

Title: Theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation.

Journal: Molecular carcinogenesis 20060301

Title: Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears.

Journal: Molecular nutrition & food research 20060201

Title: Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus.

Journal: Journal of food protection 20060201

Title: Black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of Cox-2 and induction of caspase-3 expression.

Journal: Asian Pacific journal of cancer prevention : APJCP 20060101

Title: Theaflavin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-inflammatory effect and modulation of STAT-1.

Journal: Mediators of inflammation 20060101

Title: Induction of apoptosis in human leukemia cells by black tea and its polyphenol theaflavin.

Journal: Cancer letters 20051208

Title: Creaming in black tea.

Journal: Journal of agricultural and food chemistry 20051005

Title: Stability of black tea polyphenol, theaflavin, and identification of theanaphthoquinone as its major radical reaction product.

Journal: Journal of agricultural and food chemistry 20050727

Title: [Effect of tea polyphenols on oxidative metabolism of polymorphonuclear neutrophils in healthy and obese people].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050701

Title: Molecular definition of black tea taste by means of quantitative studies, taste reconstitution, and omission experiments.

Journal: Journal of agricultural and food chemistry 20050629

Title: Antioxidative properties of black tea.

Journal: Preventive medicine 20050601

Title: Black tea polyphenols suppress cell proliferation and induce apoptosis during benzo(a)pyrene-induced lung carcinogenesis.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20050601

Title: Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.

Journal: Biochimica et biophysica acta 20050525

Title: The theaflavin fraction is responsible for the facilitatory effect of black tea at the skeletal myoneural junction.

Journal: Life sciences 20050513

Title: Black tea theaflavins suppress dioxin-induced transformation of the aryl hydrocarbon receptor.

Journal: Bioscience, biotechnology, and biochemistry 20050501

Title: Inhibition of benzo[a]pyrene induced mutagenicity and genotoxicity by black tea polyphenols theaflavins and thearubigins in multiple test systems.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050401

Title: [Study on the effect of theaflavins on the adhesion between monocyte and endothelial cells].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050401

Title: The signal transduction networks required for phosphorylation of STAT1 at Ser727 in mouse epidermal JB6 cells in the UVB response and inhibitory mechanisms of tea polyphenols.

Journal: Carcinogenesis 20050201

Title: Optimization of theaflavin biosynthesis from tea polyphenols using an immobilized enzyme system and response surface methodology.

Journal: Biotechnology letters 20050201

Title: Correlation of apoptosis with comet formation induced by tea polyphenols in human leukemia cells.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20050101

Title: Amelioration of sodium arsenite-induced clastogenicity by tea extracts in Chinese hamster v79 cells.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20050101

Title: Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20050101

Title: Ellipsometry analysis of the in vitro adsorption of tea polyphenols onto salivary pellicles.

Journal: European journal of oral sciences 20041201

Title: Antimicrobial activity of 10 different plant polyphenols against bacteria causing food-borne disease.

Journal: Biological & pharmaceutical bulletin 20041201

Title: [Preparation and component analysis of tea pigments].

Journal: Wei sheng yan jiu = Journal of hygiene research 20041101

Title: Theaflavin, a black tea extract, is a novel anti-inflammatory compound.

Journal: Critical care medicine 20041001

Title: [Studies on antioxidant constituents from black tea].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041001

Title: Black tea polyphenol theaflavins inhibit aromatase activity and attenuate tamoxifen resistance in HER2/neu-transfected human breast cancer cells through tyrosine kinase suppression.

Journal: European journal of cancer (Oxford, England : 1990) 20040901

Title: The theaflavin monomers inhibit the cancer cells growth in vitro.

Journal: Acta biochimica et biophysica Sinica 20040701

Title: Identification of the astringent taste compounds in black tea infusions by combining instrumental analysis and human bioresponse.

Journal: Journal of agricultural and food chemistry 20040602

Title: New dibenzotropolone derivatives characterized from black tea using LC/MS/MS.

Journal: Bioorganic & medicinal chemistry 20040601

Title: HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea.

Journal: Journal of agricultural and food chemistry 20040519

Title: Analysis of theaflavins and thearubigins from black tea extract by MALDI-TOF mass spectrometry.

Journal: Journal of agricultural and food chemistry 20040505

Title: Tea polyphenols inhibit acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in platelet-activating factor biosynthesis) and platelet-activating factor-induced platelet aggregation.

Journal: International archives of allergy and immunology 20040501

Title: Reaction of iron(III) with theaflavin: complexation and oxidative products.

Journal: Journal of inorganic biochemistry 20040401

Title: Comparative study of the growth-inhibitory and apoptosis-inducing activities of black tea theaflavins and green tea catechin on murine myeloid leukemia cells.

Journal: International journal of molecular medicine 20040301

Title: [Determination of theaflavins in black tea by high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20040301

Title: Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase-pathways by tea polyphenols in human prostate cancer cells.

Journal: Journal of cellular biochemistry 20040201

Title: Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities.

Journal: Bioorganic & medicinal chemistry 20040115

Title: Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040101

Title: Cocoa has more phenolic phytochemicals and a higher antioxidant capacity than teas and red wine.

Journal: Journal of agricultural and food chemistry 20031203

Title: Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.

Journal: Cancer research 20031201

Title: Fermentation characteristics of some assamica clones and process optimization of black tea manufacturing.

Journal: Journal of agricultural and food chemistry 20031022

Title: Hepatic and intestinal cytochrome P450 and conjugase activities in rats treated with black tea theafulvins and theaflavins.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030801

Title: Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial.

Journal: Archives of internal medicine 20030623

Title: Carbon-13 CP-MAS nuclear magnetic resonance studies of teas.

Journal: Solid state nuclear magnetic resonance 20030501

Title: Evaluation of the anti-oxidative effect (in vitro) of tea polyphenols.

Journal: Bioscience, biotechnology, and biochemistry 20030201

Title: Signal transduction pathways: targets for green and black tea polyphenols.

Journal: Journal of biochemistry and molecular biology 20030131

Title: Regulation of hazardous exposure by protective exposure: modulation of phase II detoxification and lipid peroxidation by Camellia sinensis and Swertia chirata.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20030101

Title: Suppression of fatty acid synthase in MCF-7 breast cancer cells by tea and tea polyphenols: a possible mechanism for their hypolipidemic effects.

Journal: The pharmacogenomics journal 20030101

Title: Modulation of arsenic induced cytotoxicity by tea.

Journal: Asian Pacific journal of cancer prevention : APJCP 20030101

Title: Studies with black tea and its constituents on leukemic cells and cell lines.

Journal: Journal of experimental & clinical cancer research : CR 20021201

Title: Tea enhances insulin activity.

Journal: Journal of agricultural and food chemistry 20021120

Title: Antimutagenic effects of black tea (World Blend) and its two active polyphenols theaflavins and thearubigins in Salmonella assays.

Journal: Phytotherapy research : PTR 20021101

Title: Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways.

Journal: Archives of pharmacal research 20021001

Title: Black tea represents a major source of dietary phenolics among regular tea drinkers.

Journal: Free radical research 20021001

Title: Comparative antimutagenic and anticlastogenic effects of green tea and black tea: a review.

Journal: Mutation research 20020901

Title: Mechanisms of chronic disease causation by nutritional factors and tobacco products and their prevention by tea polyphenols.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801

Title: Synthesis of theaflavin from epicatechin and epigallocatechin by plant homogenates and role of epicatechin quinone in the synthesis and degradation of theaflavin.

Journal: Journal of agricultural and food chemistry 20020327

Title: Evaluation of the antigenotoxic potential of monomeric and dimeric flavanols, and black tea polyphenols against heterocyclic amine-induced DNA damage in human lymphocytes using the Comet assay.

Journal: Mutation research 20020325

Title: Black tea polyphenols, theaflavins, prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P450 1A1 in cell cultures.

Journal: Journal of agricultural and food chemistry 20020102

Title: Anti-invasive effects of green tea polyphenol epigallocatechin-3-gallate (EGCG), a natural inhibitor of metallo and serine proteases.

Journal: Biological chemistry 20020101

Title: Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory skin edema and ornithine decarboxylase activity by theaflavin-3,3'-digallate in mouse.

Journal: Nutrition and cancer 20020101

Title: [Protective effect of tea pigments on mice skin photoaging induced by UV irradiation].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020101

Title: Improvement of tea leaves fermentation with Aspergillus spp. pectinase.

Journal: Journal of bioscience and bioengineering 20020101

Title: Two types of oxidative dimerization of the black tea polyphenol theaflavin.

Journal: Journal of agricultural and food chemistry 20011201

Title: Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues.

Journal: Biochemical pharmacology 20011101

Title: Anticlastogenic effects of black tea (World blend) and its two active polyphenols theaflavins and thearubigins in vivo in Swiss albino mice.

Journal: Life sciences 20011026

Title: Analysis of theaflavins in biological fluids using liquid chromatography-electrospray mass spectrometry.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010905

Title: Black tea is a powerful chemopreventor of reactive oxygen and nitrogen species: comparison with its individual catechin constituents and green tea.

Journal: Biochemical and biophysical research communications 20010601

Title: Analysis of black tea theaflavins by non-aqueous capillary electrophoresis.

Journal: Journal of chromatography. A 20010601

Title: Sahoo M, et al. Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking. Genomics Inform. 2016 Sep;14(3):96-103.

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Tags:4670-05-7 Molecular Formula|4670-05-7 MDL|4670-05-7 SMILES|4670-05-7 Theaflavin