Title: Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress.
Journal: The Journal of toxicological sciences 20130101
Title: Enhanced liver tumor promotion activity in rats subjected to combined administration of phenobarbital and orphenadrine.
Journal: The Journal of toxicological sciences 20130101
Title: Cu(II)-catalyzed asymmetric hydrosilylation of diaryl- and aryl heteroaryl ketones: application in the enantioselective synthesis of orphenadrine and neobenodine.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120611
Title: [Interaction of drugs with the primary disease - when medicines exacerbate illnesses].
Journal: Praxis 20120314
Title: Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study.
Journal: Audiology & neuro-otology 20120101
Title: Validated stability-indicating reversed-phase-HPLC method for simultaneous determination of orphenadrine citrate, caffeine and aspirin.
Journal: Chemical & pharmaceutical bulletin 20120101
Title: Orphenadrine induces secondarily generalized convulsive status epilepticus in rats.
Journal: Brain research bulletin 20110405
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Full recovery from a potentially lethal dose of orphenadrine ingestion using conservative treatment: a case report.
Journal: Human & experimental toxicology 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Opiate sparing effect of fixed combination of diclophenac and orphenadrine after unilateral total hip arthroplasty: A double-blind, randomized, placebo-controlled, multi-centre clinical trial.
Journal: Wiener medizinische Wochenschrift (1946) 20101101
Title: Determination of orphenadrine plasma levels using HPLC with diode array detection and a novel solid-phase extraction procedure in psychiatric patients.
Journal: Journal of pharmaceutical and biomedical analysis 20091015
Title: The use of antipsychotic and anticholinergic antiparkinson drugs in Norway after the withdrawal of orphenadrine.
Journal: British journal of clinical pharmacology 20090801
Title: The first asymmetric halogen/metal-exchange reaction: desymmetrization of alcohols with enantiotopic bromoarene substituents.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090706
Title: Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine.
Journal: Pain 20090401
Title: The use and potential abuse of anticholinergic antiparkinson drugs in Norway: a pharmacoepidemiological study.
Journal: British journal of clinical pharmacology 20090201
Title: Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
Journal: The Journal of pharmacy and pharmacology 20090101
Title: Influence of orphenadrine upon the protective activity of various antiepileptics in the maximal electroshock-induced convulsions in mice.
Journal: Pharmacological reports : PR 20090101
Title: Pharmacokinetic, metabolism and withdrawal time of orphenadrine in camels (Camelus dromedarius) after intravenous administration.
Journal: Research in veterinary science 20081201
Title: [Diclofenac/orphenadrine as a combined analgetic in post-operative relief of pain].
Journal: Orvosi hetilap 20080928
Title: Effect of warnings in a medical journal on the use of orphenadrine.
Journal: Journal of evaluation in clinical practice 20080801
Title: Are there alternatives to the use of quinine to treat nocturnal leg cramps?
Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20080201
Title: Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.
Journal: The Journal of pharmacy and pharmacology 20080101
Title: Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20071201
Title: Determination of paracetamol and orphenadrine citrate in pharmaceutical tablets by modeling of spectrophotometric data using partial least-squares and artificial neural networks.
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071001
Title: Evaluation of enantioselective binding of antihistamines to human serum albumin by ACE.
Journal: Electrophoresis 20070801
Title: [Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070701
Title: Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient.
Journal: Archives of gerontology and geriatrics 20070101
Title: Propofol metabolism is enhanced after repetitive ketamine administration in rats: the role of cytochrome P-450 2B induction.
Journal: British journal of anaesthesia 20060901
Title: Acute adverse cutaneous reaction after the concomitant use of venlafaxine and orphenadrine citrate plus paracetamol in a depressed patient.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20060901
Title: Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060901
Title: Pharmacokinetic study of orphenadrine using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Torsades de pointes in congenital long QT syndrome following low-dose orphenadrine.
Journal: International journal of clinical practice 20060501
Title: Catanionic mixtures involving a drug: a rather general concept that can be utilized for prolonged drug release from gels.
Journal: Journal of pharmaceutical sciences 20060401
Title: Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes.
Journal: Life sciences 20050701
Title: Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials from capsaicin-induced hyperalgesic human skin.
Journal: Drugs in R&D 20050101
Title: Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson's disease.
Journal: Experimental neurology 20041001
Title: Objective high-frequency tinnitus of middle-ear myoclonus.
Journal: The Journal of laryngology and otology 20040301
Title: [Diclofenac 75mg. and 30 mg. orfenadine (Neodolpasse) versus placebo and piroxicam in postoperative analgesia after arthroscopy].
Journal: Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 20040101
Title: Analgesic effects of low-dose intravenous orphenadrine in the state of capsaicin hyperalgesia. A randomised, placebo-controlled, double-blind cross-over study using laser somatosensory evoked potentials obtained from capsaicin-irritated skin in healthy volunteers.
Journal: Arzneimittel-Forschung 20040101
Title: Upregulation of cytochromes P450 2B in rat liver by orphenadrine.
Journal: British journal of pharmacology 20030601
Title: Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine.
Journal: Journal of neurotrauma 20030601
Title: Therapeutic response of benzodiazepine, orphenadrine citrate and occlusal splint association in TMD pain.
Journal: Cranio : the journal of craniomandibular practice 20030401
Title: Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats.
Journal: Psychopharmacology 20030201
Title: Spectrophotometric determination of phenylephrine HCl and orphenadrine citrate in pure and in dosage forms.
Journal: Journal of pharmaceutical and biomedical analysis 20021107
Title: Nefopam, an analogue of orphenadrine, protects against both NMDA receptor-dependent and independent veratridine-induced neurotoxicity.
Journal: Amino acids 20020101
Title: Acute intoxication with orphenadrine and clozapine.
Journal: Forensic science international 20011115
Title: Non-sustained ventricular tachycardia due to low-dose orphenadrine.
Journal: The American journal of medicine 20011001
Title: Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
Journal: British journal of anaesthesia 20010401
Title: Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo.
Journal: British journal of pharmacology 20010201
Title: [Experience gained with the drug amizon in the treatment of patients with mumps, with special reference to its effects on some biochemical markers].
Journal: Likars'ka sprava 20010101
Title: [Diagnostic image (17). Acute dystonia induced by prochlorperazine].
Journal: Nederlands tijdschrift voor geneeskunde 20001223
Title: Examination of purported probes of human CYP2B6.
Journal: Pharmacogenetics 19970601
Title: Reversal of orphenadrine-induced ventricular tachycardia with physostigmine.
Journal: The Journal of emergency medicine 19910101
Title: Mental impairment in Parkinson's disease. The role of anticholinergic drugs.
Journal: Acta psychiatrica Belgica 19840101
Title: [Orphenadrine poisoning].
Journal: Ugeskrift for laeger 19810316
Title: An extrapyramidal syndrome after lithium therapy.
Journal: The British journal of psychiatry : the journal of mental science 19800201
Title: A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy.
Journal: The Journal of international medical research 19760101
Title: Visual hallucinations and delirium during treatment with amantadine (Symmetrel).
Journal: Journal of the American Geriatrics Society 19750501
Title: [Pilot study on the effects of an antiparkinson anticholinergic agent during depressive conditions].
Journal: L'Encephale 19750101
Title: Abnormal involuntary movements induced by anticholinergic therapy.
Journal: Acta neurologica Scandinavica 19740101
Title: Fluphenazine enanthate and fluphenazine decanoate: a comparison of their duration of action and motor side effects.
Journal: The American journal of psychiatry 19730701
Title: Haloperidol-desipramine interaction in mice, rats and man.
Journal: Chemico-biological interactions 19700801
Title: A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
Journal: The British journal of psychiatry : the journal of mental science 19660601
Title: Kornhuber, J., et al., Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies. J Neural Transm Gen Sect, 1995. 102(3): p. 237-46.
Title: Pubill, D., et al., Assessment of the adrenergic effects of orphenadrine in rat vas deferens. J Pharm Pharmacol, 1999. 51(3): p. 307-12.
