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470716-51-9,MFCD11846611
Catalog No.:AA00DB0A

470716-51-9 | 2-((4-Chlorophenylsulfonyl)methyl)-1,4-difluorobenzene

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Purity
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Price(USD)
Quantity
  
1mg
>95%
1 week  
$299.00   $209.00
- +
5mg
>95%
1 week  
$319.00   $223.00
- +
10mg
>95%
1 week  
$358.00   $250.00
- +
500mg
>95%
1 week  
$838.00   $587.00
- +
1g
>95%
1 week  
$1,212.00   $848.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DB0A
Chemical Name:
2-((4-Chlorophenylsulfonyl)methyl)-1,4-difluorobenzene
CAS Number:
470716-51-9
Molecular Formula:
C13H9ClF2O2S
Molecular Weight:
302.7242
MDL Number:
MFCD11846611
SMILES:
Clc1ccc(cc1)S(=O)(=O)Cc1cc(F)ccc1F
Properties
Computed Properties
 
Complexity:
388  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
3.5  

Downstream Synthesis Route

[1]JournalofOrganicChemistry,2007,vol.72,p.4149-4155

[2]JournalofOrganicChemistry,2007,vol.72,p.4149-4155

[3]JournalofOrganicChemistry,2007,vol.72,p.4149-4155

[4]JournalofOrganicChemistry,2007,vol.72,p.4149-4155

[1]Patent:EP1466898,2004,A1.Locationinpatent:Page20;21

[2]Patent:EP1640366,2006,A1.Locationinpatent:Page/Pagecolumn16

470716-51-9    83067-20-3   
2-6-(t-Butyldimethylsilyloxy)-1-(4-chlorophenyl)sulfonylhexyl-1,4-difluorobenzene 

[1]Patent:EP1466898,2004,A1.Locationinpatent:Page36;37

470716-51-9    929-37-3   
2-1-(4-Chlorophenyl)sulfonyl-3-(2-vinyloxyethoxy)propyl-1,4-difluorobenzene 

[1]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP1466898,2004,A1Locationinpatent:Page38

[1]Patent:EP1466898,2004,A1.Locationinpatent:Page192

Literature

Title: Recent advances in the identification of gamma-secretase inhibitors to clinically test the Abeta oligomer hypothesis of Alzheimer's disease.

Journal: Journal of medicinal chemistry 20091022

Title: Aryl sulfones: a new class of gamma-secretase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20050516

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SDS
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Tags:470716-51-9 Molecular Formula|470716-51-9 MDL|470716-51-9 SMILES|470716-51-9 2-((4-Chlorophenylsulfonyl)methyl)-1,4-difluorobenzene