Title: Alisol A 24-acetate ameliorates nonalcoholic steatohepatitis by inhibiting oxidative stress and stimulating autophagy through the AMPK/mTOR pathway.
Journal: Chemico-biological interactions 20180801
Title: Aryl hydrocarbon receptor (AhR) mediated short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on bile acid homeostasis in mice.
Journal: Toxicology and applied pharmacology 20180315
Title: Activation of intestinal GR-FXR and PPARα-UGT signaling exacerbates ibuprofen-induced enteropathy in mice.
Journal: Archives of toxicology 20180301
Title: Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170301
Title: Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.
Journal: Toxicology letters 20170104
Title: Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation.
Journal: Acta pharmacologica Sinica 20170101
Title: Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation.
Journal: Toxicology and applied pharmacology 20170101
Title: Differential modulation of FXR activity by chlorophacinone and ivermectin analogs.
Journal: Toxicology and applied pharmacology 20161215
Title: UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats.
Journal: Toxicology and applied pharmacology 20161115
Title: Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation.
Journal: Inflammatory bowel diseases 20161001
Title: Obeticholic Acid: First Global Approval.
Journal: Drugs 20160801
Title: Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes.
Journal: Life sciences 20160701
Title: Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice.
Journal: The Journal of biological chemistry 20160129
Title: Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.
Journal: The Journal of clinical investigation 20150901
Title: The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20150401
Title: Individual bile acids have differential effects on bile acid signaling in mice.
Journal: Toxicology and applied pharmacology 20150215
Title: Urinary bile acids as biomarkers for liver diseases II. Signature profiles in patients.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201
Title: Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3.
Journal: Molecular endocrinology (Baltimore, Md.) 20150201
Title: Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics.
Journal: Molecular pharmaceutics 20150105
Title: Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum.
Journal: The Journal of pharmacology and experimental therapeutics 20141001
Title: Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20141001
Title: 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.
Journal: Molecular metabolism 20140801
Title: Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140301
Title: Suppression of autophagic flux by bile acids in hepatocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140201
Title: Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.
Journal: Scientific reports 20140101
Title: Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats.
Journal: Toxicology letters 20130607
Title: Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
Journal: Hepatology (Baltimore, Md.) 20130201
Title: An improved synthesis of 6α-ethylchenodeoxycholic acid (6ECDCA), a potent and selective agonist for the Farnesoid X Receptor (FXR).
Journal: Steroids 20121101
Title: Testosterone and farnesoid X receptor agonist INT-747 counteract high fat diet-induced bladder alterations in a rabbit model of metabolic syndrome.
Journal: The Journal of steroid biochemistry and molecular biology 20121001
Title: Specific bile acids inhibit hepatic fatty acid uptake in mice.
Journal: Hepatology (Baltimore, Md.) 20121001
Title: Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19.
Journal: The Journal of steroid biochemistry and molecular biology 20121001
Title: BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001
Title: Formation of tubules by p-tert-butylphenylamide derivatives of chenodeoxycholic and ursodeoxycholic acids in aqueous solution.
Journal: Steroids 20121001
Title: In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum.
Journal: Applied microbiology and biotechnology 20120901
Title: Effect of probiotics on serum bile acids in patients with ulcerative colitis.
Journal: Hepato-gastroenterology 20120901
Title: Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells.
Journal: Journal of cellular biochemistry 20120901
Title: Kinetics of bile salt binding to liposomes revealed by carboxyfluorescein release and mathematical modeling.
Journal: Journal of liposome research 20120901
Title: Discovery and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists.
Journal: Journal of medicinal chemistry 20120823
Title: Clinical reasoning: a case of treatable spastic paraparesis.
Journal: Neurology 20120807
Title: Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.
Journal: Analytical biochemistry 20120801
Title: Determination of binding affinity for chenodeoxycholate in equilibrium with sulfobutylether-β-cyclodextrin.
Journal: Journal of pharmaceutical sciences 20120801
Title: Farnesoid X receptor regulates vascular reactivity through nitric oxide mechanism.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120801
Title: Triterpenes from Alisma orientalis act as farnesoid X receptor agonists.
Journal: Bioorganic & medicinal chemistry letters 20120715
Title: Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation.
Journal: Cell cycle (Georgetown, Tex.) 20120715
Title: In situ investigation of dye adsorption on TiO2 films using a quartz crystal microbalance with a dissipation technique.
Journal: Physical chemistry chemical physics : PCCP 20120707
Title: Putative irreversible inhibitors of the human sodium-dependent bile acid transporter (hASBT; SLC10A2) support the role of transmembrane domain 7 in substrate binding/translocation.
Journal: Pharmaceutical research 20120701
Title: Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health.
Journal: Journal of hepatology 20120701
Title: Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120701
Title: Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity.
Journal: Biochemical pharmacology 20120615
Title: Activation of farnesoid X receptor attenuates liver injury in systemic lupus erythematosus.
Journal: Rheumatology international 20120601
Title: Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats.
Journal: European journal of drug metabolism and pharmacokinetics 20120601
Title: Molecular interactions between selected sodium salts of bile acids and morphine hydrochloride.
Journal: Colloids and surfaces. B, Biointerfaces 20120601
Title: Progressive familial intrahepatic cholestasis and inborn errors of bile acid synthesis.
Journal: Clinics and research in hepatology and gastroenterology 20120601
Title: [Progress in the ligands and their complex structures of farnesoid X receptor].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120601
Title: The effect of physiological concentrations of bile acids on in vitro growth of Mycobacterium tuberculosis.
Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20120523
Title: Molecular dynamics simulations on the aggregation behavior of indole type organic dye molecules in dye-sensitized solar cells.
Journal: Journal of molecular modeling 20120501
Title: Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.
Journal: The FEBS journal 20120501
Title: Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2.
Journal: Bioorganic & medicinal chemistry 20120501
Title: Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist.
Journal: Bioorganic & medicinal chemistry letters 20120501
Title: The Sigma class glutathione transferase from the liver fluke Fasciola hepatica.
Journal: PLoS neglected tropical diseases 20120501
Title: Biophysical investigations into the interactions of endotoxins with bile acids.
Journal: Innate immunity 20120401
Title: Cerebrotendinous xanthomatosis revealed in drug-resistant epilepsy diagnostic workup.
Journal: The American journal of the medical sciences 20120401
Title: Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα.
Journal: Journal of lipid research 20120401
Title: Sesquiterpenoids from Atractylodes macrocephala act as farnesoid X receptor and progesterone receptor modulators.
Journal: Bioorganic & medicinal chemistry letters 20120315
Title: High-performance organic materials for dye-sensitized solar cells: triarylene-linked dyads with a 4-tert-butylphenylamine donor.
Journal: Chemistry, an Asian journal 20120305
Title: Comparative studies on animal models for Opisthorchis viverrini infection: host interaction through susceptibility and pathology.
Journal: Parasitology research 20120301
Title: Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.
Journal: Basic & clinical pharmacology & toxicology 20120301
Title: Multiple functions of a multi-component mating pheromone in sea lamprey Petromyzon marinus.
Journal: Journal of fish biology 20120301
Title: Mitochondrial oxidative stress alters a pathway in Caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates.
Journal: PLoS genetics 20120301
Title: In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.
Journal: Pharmaceutical research 20120201
Title: A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor.
Journal: Toxicology and applied pharmacology 20120115
Title: Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.
Journal: Journal of medicinal chemistry 20120112
Title: The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABA(A) receptors.
Journal: Neuroscience letters 20120111
Title: A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes.
Journal: Hepatology (Baltimore, Md.) 20120101
Title: Three siblings with Cerebrotendinous Xanthomatosis: a novel mutation in the CYP27A1 gene.
Journal: European journal of medical genetics 20120101
Title: Bile Acid signaling in liver metabolism and diseases.
Journal: Journal of lipids 20120101
Title: Testosterone protects from metabolic syndrome-associated prostate inflammation: an experimental study in rabbit.
Journal: The Journal of endocrinology 20120101
Title: Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium.
Journal: Journal of lipid research 20120101
Title: Eicosapentaenoic acid and docosahexaenoic acid synergistically attenuate bile acid-induced hepatocellular apoptosis.
Journal: JPEN. Journal of parenteral and enteral nutrition 20120101
Title: Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells.
Journal: Molecular pharmaceutics 20120101
Title: Waterborne manganese exposure alters plasma, brain, and liver metabolites accompanied by changes in stereotypic behaviors.
Journal: Neurotoxicology and teratology 20120101
Title: Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120101
Title: FXR protects lung from lipopolysaccharide-induced acute injury.
Journal: Molecular endocrinology (Baltimore, Md.) 20120101
Title: Magnesium chenoursodeoxycholic acid ameliorates carbon tetrachloride-induced liver fibrosis in rats.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120101
Title: Nuclear receptors in nonalcoholic Fatty liver disease.
Journal: Journal of lipids 20120101
Title: Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target.
Journal: Journal of lipids 20120101
Title: Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes.
Journal: Frontiers in pharmacology 20120101
Title: Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.
Journal: PloS one 20120101
Title: Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts.
Journal: PloS one 20120101
Title: Fetal outcomes in pregnancies complicated by intrahepatic cholestasis of pregnancy in a Northern California cohort.
Journal: PloS one 20120101
Title: Gender-divergent profile of bile acid homeostasis during aging of mice.
Journal: PloS one 20120101
Title: Oral gallstone dissolution therapies.
Journal: Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20120101
Title: Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice.
Journal: PloS one 20120101
Title: Effects of human and porcine bile on the proteome of Helicobacter hepaticus.
Journal: Proteome science 20120101
Title: Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding.
Journal: PloS one 20120101
Title: Medical therapy of acromegaly.
Journal: International journal of endocrinology 20120101
Title: Bile acids specifically increase hepatitis C virus RNA-replication.
Journal: PloS one 20120101
Title: A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.
Journal: Journal of lipids 20120101
Title: Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases.
Journal: Experimental diabetes research 20120101
Title: Effect of ursodeoxycholic Acid alone and ursodeoxycholic Acid plus domperidone on radiolucent gallstones and gallbladder contractility in humans.
Journal: Gastroenterology research and practice 20120101
Title: Epigenetics modifications and therapeutic prospects in human thyroid cancer.
Journal: Frontiers in endocrinology 20120101
Title: The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.
Journal: Frontiers in pharmacology 20120101
Title: Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.
Journal: PloS one 20120101
Title: Alterations in the detergent-induced membrane permeability and solubilization of saturated phosphatidylcholine/cholesterol liposomes: effects of poly(ethylene glycol)-conjugated lipid.
Journal: Chemical & pharmaceutical bulletin 20120101
Title: Cerebrotendinous xanthomatosis: a rare disorder with a rare presentation.
Journal: BMJ case reports 20120101
Title: Metabolic profiling reveals sphingosine-1-phosphate kinase 2 and lyase as key targets of (phyto-) estrogen action in the breast cancer cell line MCF-7 and not in MCF-12A.
Journal: PloS one 20120101
Title: Improvement of low bioavailability of a novel factor Xa inhibitor through formulation of cationic additives in its oral dosage form.
Journal: International journal of pharmaceutics 20111215
Title: Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice.
Journal: British journal of pharmacology 20111201
Title: Role of farnesoid X receptor (FXR) in the process of differentiation of bone marrow stromal cells into osteoblasts.
Journal: Bone 20111201
Title: Targeting bile acids in the treatment of constipation.
Journal: Expert review of gastroenterology & hepatology 20111201
Title: Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.
Journal: Bioorganic & medicinal chemistry 20111201
Title: Searching for the main anti-bacterial components in artificial Calculus bovis using UPLC and microcalorimetry coupled with multi-linear regression analysis.
Journal: Journal of separation science 20111201
Title: Effect of twice-daily oral administration of hydrocortisone on the bile acids composition of gallbladder bile in dogs.
Journal: American journal of veterinary research 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Natural products from the Lithistida: a review of the literature since 2000.
Journal: Marine drugs 20111201
Title: Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum.
Journal: Bioorganic & medicinal chemistry 20111115
Title: The role of the acquisition methods in the analysis of natural and synthetic steroids and cholic acids by gas chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20111111
Title: Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor.
Journal: British journal of pharmacology 20111101
Title: Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression.
Journal: Hepatology (Baltimore, Md.) 20111101
Title: Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells.
Journal: Intervirology 20111001
Title: A randomized placebo-controlled phase IIb trial of a3309, a bile acid transporter inhibitor, for chronic idiopathic constipation.
Journal: The American journal of gastroenterology 20111001
Title: Cerebrotendinous xanthomatosis in Spain: clinical, prognostic, and genetic survey.
Journal: European journal of neurology 20111001
Title: Dose-response of five bile acids on serum and liver bile Acid concentrations and hepatotoxicty in mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111001
Title: Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells.
Journal: Apoptosis : an international journal on programmed cell death 20111001
Title: Primary bile acid therapy during pregnancy in patients with 3β-hydroxy-Δ5 -C27 -steroid oxidoreductase deficiency.
Journal: Pediatrics international : official journal of the Japan Pediatric Society 20111001
Title: Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression.
Journal: Oncogene 20110929
Title: [Usefulness of cholestanol levels in the diagnosis and follow-up of patients with cerebrotendinous xanthomatosis].
Journal: Neurologia (Barcelona, Spain) 20110901
Title: High-dose ursodeoxycholic acid is associated with the development of colorectal neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis.
Journal: The American journal of gastroenterology 20110901
Title: Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report.
Journal: Chemistry and physics of lipids 20110901
Title: Pharmacologic and complementary and alternative medicine therapies for irritable bowel syndrome.
Journal: Gut and liver 20110901
Title: Insulin resistance as a risk factor for gallbladder stone formation in Korean postmenopausal women.
Journal: The Korean journal of internal medicine 20110901
Title: The diagnosis and treatment of primary biliary cirrhosis.
Journal: The Korean journal of hepatology 20110901
Title: β-Cyclodextrin dimers linked through their secondary faces with rigid spacer arms as hosts for bile salts.
Journal: Langmuir : the ACS journal of surfaces and colloids 20110816
Title: Carcinogenicity of deoxycholate, a secondary bile acid.
Journal: Archives of toxicology 20110801
Title: Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110801
Title: Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA.
Journal: Mini reviews in medicinal chemistry 20110801
Title: Cerebrotendinous xanthomatosis: a treatable disease with juvenile cataracts as a presenting sign.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20110801
Title: Metabolomic investigation of cholestasis in a rat model using ultra-performance liquid chromatography/tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20110715
Title: Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma.
Journal: Molecular & cellular proteomics : MCP 20110701
Title: Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec).
Journal: The British journal of nutrition 20110701
Title: Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.
Journal: The Biochemical journal 20110615
Title: Chenodeoxycholic acid stabilization of LDL receptor mRNA depends on 3'-untranslated region and AU-rich element-binding protein.
Journal: Biochemical and biophysical research communications 20110603
Title: Visualisation of treatment response in a case of cerebrotendinous xanthomatosis.
Journal: Journal of neurology, neurosurgery, and psychiatry 20110601
Title: SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110601
Title: Suppression of cytochrome P450 reductase (POR) expression in hepatoma cells replicates the hepatic lipidosis observed in hepatic POR-null mice.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601
Title: Clinical relevance and neurophysiological correlates of spasticity in cerebrotendinous xanthomatosis.
Journal: Journal of neurology 20110501
Title: Effects of intervention with sulindac and inulin/VSL#3 on mucosal and luminal factors in the pouch of patients with familial adenomatous polyposis.
Journal: International journal of colorectal disease 20110501
Title: Farnesoid X receptor agonists for primary biliary cirrhosis.
Journal: Current opinion in gastroenterology 20110501
Title: Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110501
Title: Protective effects of Mg-CUD against D-galactosamine-induced hepatotoxicity in rats.
Journal: European journal of pharmacology 20110425
Title: Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease.
Journal: Gut 20110401
Title: Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1).
Journal: Steroids 20110401
Title: Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401
Title: Helicobacter hepaticus--induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response.
Journal: Cancer research 20110401
Title: Low levels of bile acids increase bacterial uptake in colonic biopsies from patients with collagenous colitis in remission.
Journal: Alimentary pharmacology & therapeutics 20110401
Title: Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor.
Journal: Journal of medicinal chemistry 20110310
Title: Synthesis and in vitro evaluation of gabapentin prodrugs that target the human apical sodium-dependent bile acid transporter (hASBT).
Journal: Journal of pharmaceutical sciences 20110301
Title: Engineered three-dimensional liver mimics recapitulate critical rat-specific bile acid pathways.
Journal: Tissue engineering. Part A 20110301
Title: Pathophysiological relevance of apical large-conductance Ca²+-activated potassium channels in pancreatic duct epithelial cells.
Journal: Gut 20110301
Title: Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter.
Journal: Biochimica et biophysica acta 20110301
Title: Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis.
Journal: Hepatology (Baltimore, Md.) 20110301
Title: Mitochondrial disorders in NSAIDs-induced small bowel injury.
Journal: Journal of clinical biochemistry and nutrition 20110301
Title: The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110201
Title: Response of cricopharyngeus muscle to esophageal stimulation by mechanical distension and acid and bile perfusion.
Journal: The Annals of otology, rhinology, and laryngology 20110201
Title: Determination of bile acids in pig liver, pig kidney and bovine liver by gas chromatography-chemical ionization tandem mass spectrometry with total ion chromatograms and extraction ion chromatograms.
Journal: Journal of chromatography. A 20110121
Title: Gas chromatography-mass spectrometry-based simultaneous quantitative analytical method for urinary oxysterols and bile acids in rats.
Journal: Analytical biochemistry 20110115
Title: Screening for novel antibacterial agents based on the activities of compounds on metabolism of Escherichia coli: a microcalorimetric study.
Journal: Journal of hazardous materials 20110115
Title: Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.
Journal: Journal of chromatography. A 20110107
Title: Effects of farnesoid X receptor on the expression of the fatty acid synthetase and hepatic lipase.
Journal: Molecular biology reports 20110101
Title: Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells.
Journal: Gut 20110101
Title: The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate.
Journal: Protein science : a publication of the Protein Society 20110101
Title: The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin.
Journal: Clinical endocrinology 20110101
Title: SPECT imaging for brain improvement quantification in a patient with cerebrotendinous xanthomatosis.
Journal: Clinical nuclear medicine 20110101
Title: Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.
Journal: The American journal of pathology 20110101
Title: Discovering networks of perturbed biological processes in hepatocyte cultures.
Journal: PloS one 20110101
Title: Inflammatory pseudo-tumor of the liver: a rare pathological entity.
Journal: World journal of surgical oncology 20110101
Title: Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases.
Journal: Journal of biomedicine & biotechnology 20110101
Title: The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.
Journal: BMC biochemistry 20110101
Title: Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance.
Journal: BMC microbiology 20110101
Title: Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters.
Journal: PloS one 20110101
Title: Mechanisms of oxysterol-induced carcinogenesis.
Journal: Lipids in health and disease 20110101
Title: Sex differences in drug disposition.
Journal: Journal of biomedicine & biotechnology 20110101
Title: FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.
Journal: PloS one 20110101
Title: Cattle bile aggravates diclofenac sodium-induced small intestinal injury in mice.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Neuromuscular abnormality and autonomic dysfunction in patients with cerebrotendinous xanthomatosis.
Journal: BMC neurology 20110101
Title: Herbert Falk: a vital force in the renaissance of bile acid research and bile acid therapy.
Journal: Digestive diseases (Basel, Switzerland) 20110101
Title: Biliary bicarbonate secretion constitutes a protective mechanism against bile acid-induced injury in man.
Journal: Digestive diseases (Basel, Switzerland) 20110101
Title: Genetic variants of the bile salt export pump: inducers and modifiers of liver diseases.
Journal: Digestive diseases (Basel, Switzerland) 20110101
Title: Statistical methods for assays with limits of detection: Serum bile acid as a differentiator between patients with normal colons, adenomas, and colorectal cancer.
Journal: Journal of carcinogenesis 20110101
Title: Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults.
Journal: Nutrition & metabolism 20110101
Title: TGR5: a novel target for weight maintenance and glucose metabolism.
Journal: Experimental diabetes research 20110101
Title: Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.
Journal: PloS one 20110101
Title: Pancreatic ductal bicarbonate secretion: challenge of the acinar Acid load.
Journal: Frontiers in physiology 20110101
Title: Transformation of chenodeoxycholic acid by thermophilic Geobacillus stearothermophilus.
Journal: Biotechnology and applied biochemistry 20110101
Title: Impact of bile acids on the growth of human cholangiocarcinoma via FXR.
Journal: Journal of hematology & oncology 20110101
Title: 2 Novel deletions of the sterol 27-hydroxylase gene in a Chinese Family with Cerebrotendinous Xanthomatosis.
Journal: BMC neurology 20110101
Title: Enteric microbiome metabolites correlate with response to simvastatin treatment.
Journal: PloS one 20110101
Title: Mychonastes afer HSO-3-1 as a potential new source of biodiesel.
Journal: Biotechnology for biofuels 20110101
Title: The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis.
Journal: PloS one 20110101
Title: Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus.
Journal: PloS one 20110101
Title: Astragalus polysaccharides lowers plasma cholesterol through mechanisms distinct from statins.
Journal: PloS one 20110101
Title: Active transport of bile acids decreases mucin 2 in neonatal ileum: implications for development of necrotizing enterocolitis.
Journal: PloS one 20110101
Title: Cerebrotendinous xanthomatosis: a rare cause of spinocerebellar syndrome.
Journal: Neurologia i neurochirurgia polska 20110101
Title: Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates.
Journal: Molecular pharmaceutics 20101206
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice.
Journal: Journal of lipid research 20101201
Title: Endocrine, metabolic, nutritional, and toxic disorders leading to dementia.
Journal: Annals of Indian Academy of Neurology 20101201
Title: Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid.
Journal: Bioconjugate chemistry 20101117
Title: Application of near infrared spectroscopy for rapid analysis of intermediates of Tanreqing injection.
Journal: Journal of pharmaceutical and biomedical analysis 20101102
Title: Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice.
Journal: Journal of lipid research 20101101
Title: Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis.
Journal: Gastroenterology 20101101
Title: The influence of NaCl on hydrophobicity of selected, pharmacologically active bile acids expressed with chromatographic retention index and critical micellar concentration.
Journal: Colloids and surfaces. B, Biointerfaces 20101101
Title: Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells.
Journal: Journal of pediatric gastroenterology and nutrition 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Analysis of serum bile acids by isotope dilution-mass spectrometry to assess the performance of routine total bile acid methods.
Journal: Annals of clinical biochemistry 20101101
Title: Cerebrotendinous xanthomatosis: a treatable hereditary neuro-metabolic disease.
Journal: Clinics (Sao Paulo, Brazil) 20101101
Title: A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.
Journal: Lab on a chip 20101021
Title: Quantification of the 15 major human bile acids and their precursor 7α-hydroxy-4-cholesten-3-one in serum by liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015
Title: Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Δ4(5)-isomerase and 3α- and 3β-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot.
Journal: The Journal of steroid biochemistry and molecular biology 20101001
Title: Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid.
Journal: Journal of bacteriology 20101001
Title: Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism.
Journal: Hepatology (Baltimore, Md.) 20101001
Title: Modelling phase transition kinetics of chenodeoxycholic acid with the Runge-Kutta method.
Journal: Journal of pharmaceutical and biomedical analysis 20100921
Title: Simple and practical derivatization procedure for enhanced detection of carboxylic acids in liquid chromatography-electrospray ionization-tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20100905
Title: Molecular genetic and bile acid profiles in two Japanese patients with 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase deficiency.
Journal: Pediatric research 20100901
Title: Two time-point assessment of bile acid kinetics in humans using stable isotopes.
Journal: Isotopes in environmental and health studies 20100901
Title: Construction of confidence regions for isotopic abundance patterns in LC/MS data sets for rigorous determination of molecular formulas.
Journal: Analytical chemistry 20100901
Title: [Chemical constituents of bear bile].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
Title: Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT.
Journal: International journal of pharmaceutics 20100830
Title: Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway.
Journal: Journal of lipid research 20100801
Title: Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.
Journal: Journal of lipid research 20100801
Title: A putative role of micro RNA in regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes.
Journal: Journal of lipid research 20100801
Title: 3β-hydroxy-Δ⁵-C₂₇-steroid dehydrogenase/isomerase deficiency in a patient who underwent oral bile acid therapy for 10 years and delivered two healthy infants.
Journal: Pediatrics international : official journal of the Japan Pediatric Society 20100801
Title: Effects of DCA on Cell Cycle Proteins in Colonocytes.
Journal: Journal of the Korean Society of Coloproctology 20100801
Title: Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines.
Journal: European journal of medicinal chemistry 20100701
Title: Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100701
Title: Bile acid changes after high-dose ursodeoxycholic acid treatment in primary sclerosing cholangitis: Relation to disease progression.
Journal: Hepatology (Baltimore, Md.) 20100701
Title: Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.
Journal: Aging 20100701
Title: Farnesoid X receptor activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease.
Journal: Circulation research 20100625
Title: [Effects of bile acids on expression of interleukin-6 and cell viability in QBC939 cell line].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20100615
Title: Determination of multicomponent contents in Calculus bovis by ultra-performance liquid chromatography-evaporative light scattering detection and its application for quality control.
Journal: Journal of separation science 20100601
Title: Hydrophobicity and haemolytic potential of oxo derivatives of cholic, deoxycholic and chenodeoxycholic acids.
Journal: Steroids 20100601
Title: Bile acids: short and long term effects in the intestine.
Journal: Scandinavian journal of gastroenterology 20100601
Title: Titration of bile acid supplements in 3beta-hydroxy-Delta 5-C27-steroid dehydrogenase/isomerase deficiency.
Journal: Journal of pediatric gastroenterology and nutrition 20100601
Title: Neuropathy, retinopathy, and glucose-lowering treatments.
Journal: Diabetes care 20100601
Title: Characterization of porcine pregnane X receptor, farnesoid X receptor and their splice variants.
Journal: Experimental biology and medicine (Maywood, N.J.) 20100601
Title: Pharmacotherapy of cholestatic liver diseases.
Journal: Journal of digestive diseases 20100601
Title: NMR characterization of the interaction of the Salmonella type III secretion system protein SipD and bile salts.
Journal: Biochemistry 20100518
Title: Regulation of bile acid synthesis by fat-soluble vitamins A and D.
Journal: The Journal of biological chemistry 20100507
Title: Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice.
Journal: Journal of hepatology 20100501
Title: Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.
Journal: Molecular bioSystems 20100501
Title: Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271.
Journal: Anaerobe 20100401
Title: Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma.
Journal: International journal of cancer 20100401
Title: FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats.
Journal: Journal of lipid research 20100401
Title: Bile acid-activated receptors in the treatment of dyslipidemia and related disorders.
Journal: Progress in lipid research 20100401
Title: Regulation of VDR expression in rat and human intestine and liver--consequences for CYP3A expression.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401
Title: alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulator.
Journal: Biochimica et biophysica acta 20100401
Title: Salivary chenodeoxycholic acid and its glycine-conjugate: their determination method using LC-MS/MS and variation of their concentrations with increased saliva flow rate.
Journal: Steroids 20100401
Title: Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids.
Journal: Journal of hepatology 20100401
Title: Cerebrotendinous xanthomatosis presenting with severe externalized disorder: improvement after one year of treatment with chenodeoxycholic Acid.
Journal: CNS spectrums 20100401
Title: Identification of farnesoid X receptor modulators by a fluorescence polarization-based interaction assay.
Journal: Analytical biochemistry 20100315
Title: Oleanolic acid is a selective farnesoid X receptor modulator.
Journal: Phytotherapy research : PTR 20100301
Title: Impacts of different promoters on the mammalian one-hybrid assay for detecting nuclear receptor agonists.
Journal: Analytical and bioanalytical chemistry 20100301
Title: Kinetic analysis of bile acid sulfation by stably expressed human sulfotransferase 2A1 (SULT2A1).
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100301
Title: Past, present and future therapeutics for cerebellar ataxias.
Journal: Current neuropharmacology 20100301
Title: Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells.
Journal: The Journal of biological chemistry 20100219
Title: Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.
Journal: Toxicology and applied pharmacology 20100215
Title: Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?
Journal: The Journal of biological chemistry 20100212
Title: Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20100201
Title: Regulation of diurnal variation of cholesterol 7alpha-hydroxylase (CYP7A1) activity in healthy subjects.
Journal: Physiological research 20100101
Title: Variable clinical spectrum of the most common inborn error of bile acid metabolism--3beta-hydroxy-Delta 5-C27-steroid dehydrogenase deficiency.
Journal: Journal of pediatric gastroenterology and nutrition 20100101
Title: High performance liquid chromatography-tandem mass spectrometry for the determination of bile acid concentrations in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100101
Title: Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.
Journal: Pharmacotherapy 20100101
Title: Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells.
Journal: Acta pharmacologica Sinica 20100101
Title: Metabolism of bile salts in mice influences spore germination in Clostridium difficile.
Journal: PloS one 20100101
Title: Bile acids induce cdx2 expression through the farnesoid x receptor in gastric epithelial cells.
Journal: Journal of clinical biochemistry and nutrition 20100101
Title: Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection.
Journal: BMC medicine 20100101
Title: Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites.
Journal: BMC evolutionary biology 20100101
Title: Identification of novel pathogenicity loci in Clostridium perfringens strains that cause avian necrotic enteritis.
Journal: PloS one 20100101
Title: Fenofibrate in primary biliary cirrhosis: a pilot study.
Journal: The open cardiovascular medicine journal 20100101
Title: Multi-parametric neuroimaging evaluation of cerebrotendinous xanthomatosis and its correlation with neuropsychological presentations.
Journal: BMC neurology 20100101
Title: Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1.
Journal: Drug metabolism and pharmacokinetics 20100101
Title: Metabolic bone disease in lion cubs at the London Zoo in 1889: the original animal model of rickets.
Journal: Journal of biomedical science 20100101
Title: Plasma bile acids are not associated with energy metabolism in humans.
Journal: Nutrition & metabolism 20100101
Title: Analyzing the regulation of metabolic pathways in human breast cancer.
Journal: BMC medical genomics 20100101
Title: The Role of PPARα Activation in Liver and Muscle.
Journal: PPAR research 20100101
Title: A novel mutation in the sterol 27-hydroxylase gene of a woman with autosomal recessive cerebrotendinous xanthomatosis.
Journal: Orphanet journal of rare diseases 20100101
Title: The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice.
Journal: PloS one 20100101
Title: Bile acid-induced virulence gene expression of Vibrio parahaemolyticus reveals a novel therapeutic potential for bile acid sequestrants.
Journal: PloS one 20100101
Title: Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride.
Journal: Pharmacology 20100101
Title: Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting.
Journal: PloS one 20100101
Title: Antimicrobial peptides in gastrointestinal inflammation.
Journal: International journal of inflammation 20100101
Title: A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity.
Journal: PloS one 20100101
Title: Deciphering the nuclear bile acid receptor FXR paradigm.
Journal: Nuclear receptor signaling 20100101
Title: Microbial induction of immunity, inflammation, and cancer.
Journal: Frontiers in physiology 20100101
Title: Cerebrotendinous xanthomatosis associated with immune thrombocytopenia.
Journal: BMJ case reports 20100101
Title: Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.
Journal: Journal of medicinal chemistry 20091224
Title: The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria.
Journal: American journal of physiology. Renal physiology 20091201
Title: Detection of Helicobacter hepaticus in human bile samples of patients with biliary disease.
Journal: Helicobacter 20091201
Title: Developments in bile acid kinetic measurements using (13)C and (2)H: 10(5) times improved sensitivity during the last 40 years.
Journal: Isotopes in environmental and health studies 20091201
Title: Determination of critical micellar concentrations of two monoketo derivatives of cholic acid.
Journal: Colloids and surfaces. B, Biointerfaces 20091101
Title: Effect of mitiglinide on Streptozotocin-induced experimental type 2 diabetic rats: a urinary metabonomics study based on ultra-performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101
Title: CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells.
Journal: Pancreas 20091101
Title: Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration.
Journal: Diabetes care 20091101
Title: Case Report: Cerebrotendinous xanthomatosis.
Journal: The Indian journal of radiology & imaging 20091101
Title: Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.
Journal: The Journal of biological chemistry 20091016
Title: Modulation of bile acid metabolism by 1alpha-hydroxyvitamin D3 administration in mice.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091001
Title: Albumin dialysis molecular adsorbents recirculating system: impact of dialysate albumin concentration on detoxification efficacy.
Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20091001
Title: Cerebrotendinous xanthomatosis: a treatable neurodegenerative disease.
Journal: The Journal of the Association of Physicians of India 20091001
Title: Fluorescence properties of trans-ethyl-p-(dimethylamino) cinnamate in presence of bile acid host.
Journal: Journal of photochemistry and photobiology. B, Biology 20090904
Title: The mechanism of the cholesterol-lowering effect of water-insoluble fish protein in ovariectomised rats.
Journal: The British journal of nutrition 20090901
Title: The role of transporters in the pharmacokinetics of orally administered drugs.
Journal: Pharmaceutical research 20090901
Title: Characterization of the contents of ascending colon to which drugs are exposed after oral administration to healthy adults.
Journal: Pharmaceutical research 20090901
Title: Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090901
Title: Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090901
Title: Cerebrotendinous xanthomatosis (CTX): a treatable lipid storage disease.
Journal: Pediatric endocrinology reviews : PER 20090901
Title: Nutritional approaches to prevention and treatment of gallstones.
Journal: Alternative medicine review : a journal of clinical therapeutic 20090901
Title: Ferrocene-beta-cyclodextrin conjugates: synthesis, supramolecular behavior, and use as electrochemical sensors.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090817
Title: Metabonomics study of atherosclerosis rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.
Journal: Talanta 20090815
Title: Inhibition of nucleostemin upregulates CDX2 expression in HT29 cells in response to bile acid exposure: implications in the pathogenesis of Barrett's esophagus.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20090801
Title: Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells.
Journal: Journal of cellular and molecular medicine 20090801
Title: Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.
Journal: The Journal of pharmacy and pharmacology 20090801
Title: Oromandibular dystonia as a complication of cerebrotendinous xanthomatosis.
Journal: Movement disorders : official journal of the Movement Disorder Society 20090715
Title: Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease.
Journal: World journal of gastroenterology 20090707
Title: Bile acid aspiration in suspected ventilator-associated pneumonia.
Journal: Chest 20090701
Title: Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP).
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090701
Title: Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.
Journal: Molecular nutrition & food research 20090701
Title: Expression and regulation of the bile acid transporter, OSTalpha-OSTbeta in rat and human intestine and liver.
Journal: Biopharmaceutics & drug disposition 20090701
Title: Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.
Journal: The Journal of pharmacy and pharmacology 20090701
Title: Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients.
Journal: Breast cancer research and treatment 20090601
Title: Absence of glycochenodeoxycholic acid (GCDCA) in human bile is an indication of cholestasis: a 1H MRS study.
Journal: NMR in biomedicine 20090601
Title: Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090601
Title: Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans.
Journal: Pharmacogenetics and genomics 20090601
Title: Differentiated CaCo-2 cells as an in-vitro model to evaluate de-novo apolipoprotein A-I production in the small intestine.
Journal: European journal of gastroenterology & hepatology 20090601
Title: Comparison of effects of VDR versus PXR, FXR and GR ligands on the regulation of CYP3A isozymes in rat and human intestine and liver.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090512
Title: Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin.
Journal: International journal of oncology 20090501
Title: [Expression and regulation of megalin in gallbladder mucosa associated with cholesterol gallstone disease].
Journal: Zhonghua yi xue za zhi 20090428
Title: Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation.
Journal: Genes & development 20090415
Title: [The right medicine for cerebrotendinous xanthomatosis].
Journal: Nederlands tijdschrift voor geneeskunde 20090411
Title: Bile acid ratio in diagnosis of intrahepatic cholestasis of pregnancy.
Journal: American journal of perinatology 20090401
Title: FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090401
Title: Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces.
Journal: FEMS microbiology letters 20090401
Title: Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium.
Journal: Gastroenterology 20090401
Title: [Cerebrotendinous xanthomatosis: report of 4 patients].
Journal: Actas dermo-sifiliograficas 20090401
Title: ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.
Journal: Gastroenterology 20090301
Title: Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.
Journal: Hepatology (Baltimore, Md.) 20090301
Title: Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway.
Journal: PLoS pathogens 20090301
Title: The farnesoid X receptor regulates transcription of 3beta-hydroxysteroid dehydrogenase type 2 in human adrenal cells.
Journal: Molecular and cellular endocrinology 20090227
Title: Antiatherosclerotic effect of farnesoid X receptor.
Journal: American journal of physiology. Heart and circulatory physiology 20090201
Title: Lake char (Salvelinus namaycush) olfactory neurons are highly sensitive and specific to bile acids.
Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20090201
Title: Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines.
Journal: The Journal of biological chemistry 20090130
Title: Effect of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis C virus infection.
Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20090101
Title: Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.
Journal: Hepatology (Baltimore, Md.) 20090101
Title: Novel zinc porphyrin sensitizers for dye-sensitized solar cells: synthesis and spectral, electrochemical, and photovoltaic properties.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090101
Title: Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia.
Journal: Journal of natural products 20090101
Title: Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.
Journal: Hepatology (Baltimore, Md.) 20090101
Title: Chronic diarrhea and juvenile cataracts: think cerebrotendinous xanthomatosis and treat.
Journal: Pediatrics 20090101
Title: Bear bile: dilemma of traditional medicinal use and animal protection.
Journal: Journal of ethnobiology and ethnomedicine 20090101
Title: Biphasic regulation of cell death and survival by hydrophobic bile acids in HCT116 cells.
Journal: Nutrition and cancer 20090101
Title: Cefotaxime pharmacokinetics after oral application in the form of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate microvesicles in rat.
Journal: European journal of drug metabolism and pharmacokinetics 20090101
Title: Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats.
Journal: European journal of drug metabolism and pharmacokinetics 20090101
Title: Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells.
Journal: BMC cancer 20090101
Title: Regulation of bile acid and cholesterol metabolism by PPARs.
Journal: PPAR research 20090101
Title: Effect of 12-monoketocholic acid on modulation of analgesic action of morphine and tramadol.
Journal: European journal of drug metabolism and pharmacokinetics 20090101
Title: Various techniques for the surgical treatment of common bile duct stones: a meta review.
Journal: Gastroenterology research and practice 20090101
Title: Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.
Journal: PPAR research 20090101
Title: A new bile acid from the bile of Anser anser.
Journal: Natural product research 20090101
Title: Erythropoietic protoporphyria.
Journal: Orphanet journal of rare diseases 20090101
Title: A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells.
Journal: BMC genomics 20090101
Title: Functional and probiotic attributes of an indigenous isolate of Lactobacillus plantarum.
Journal: PloS one 20090101
Title: Transport assays and permeability in pathogenic mycobacteria.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: 7alpha- and 12alpha-Hydroxysteroid dehydrogenases from Acinetobacter calcoaceticus lwoffii: a new integrated chemo-enzymatic route to ursodeoxycholic acid.
Journal: Steroids 20081222
Title: The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor.
Journal: Hepatology (Baltimore, Md.) 20081201
Title: Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX.
Journal: Journal of inherited metabolic disease 20081201
Title: Physical and chemical factors influencing the germination of Clostridium difficile spores.
Journal: Journal of applied microbiology 20081201
Title: Beta-glucans in the treatment of diabetes and associated cardiovascular risks.
Journal: Vascular health and risk management 20081201
Title: Synthetic chenodeoxycholic acid derivative, HS-1200, induces apoptosis of human hepatoma cells via a mitochondrial pathway.
Journal: Cancer letters 20081108
Title: Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity.
Journal: Molecular endocrinology (Baltimore, Md.) 20081101
Title: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20081101
Title: Bile acids induce CCN2 production through p38 MAP kinase activation in human bronchial epithelial cells: a factor contributing to airway fibrosis.
Journal: Respirology (Carlton, Vic.) 20081101
Title: Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients.
Journal: Journal of pediatric gastroenterology and nutrition 20081101
Title: FXRalpha down-regulates LXRalpha signaling at the CETP promoter via a common element.
Journal: Molecules and cells 20081031
Title: Association between fecal bile acids and colorectal cancer: a meta-analysis of observational studies.
Journal: Yonsei medical journal 20081031
Title: Synthesis of sterically hindered phthalocyanines and their applications to dye-sensitized solar cells.
Journal: Dalton transactions (Cambridge, England : 2003) 20081028
Title: Effect of coadsorbent on the photovoltaic performance of squaraine sensitized nanocrystalline solar cells.
Journal: Nanotechnology 20081022
Title: A chenodeoxycholic derivative, HS-1200, induces apoptosis and cell cycle modulation via Egr-1 gene expression control on human hepatoma cells.
Journal: Cancer letters 20081018
Title: Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation.
Journal: Bioorganic & medicinal chemistry letters 20081015
Title: Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001
Title: New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines.
Journal: Bioorganic & medicinal chemistry 20080915
Title: The synthesis of MP-CDCA conjugates and dissolution kinetics of model cholesterol gallstones.
Journal: Acta biomaterialia 20080901
Title: Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma.
Journal: Cancer science 20080901
Title: Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig.
Journal: Gut 20080801
Title: Critical micellar concentrations of keto derivatives of selected bile acids: thermodynamic functions of micelle formation.
Journal: Colloids and surfaces. B, Biointerfaces 20080715
Title: Teaching neuroimage: cerebrotendinous xanthomatosis.
Journal: Neurology 20080708
Title: Impact of impurity on kinetic estimates from transport and inhibition studies.
Journal: The Journal of pharmacology and experimental therapeutics 20080701
Title: Adaptive responses of renal organic anion transporter 3 (OAT3) during cholestasis.
Journal: American journal of physiology. Renal physiology 20080701
Title: Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.
Journal: PLoS neglected tropical diseases 20080701
Title: The novel compounds that activate farnesoid X receptor: the diversity of their effects on gene expression.
Journal: Journal of pharmacological sciences 20080701
Title: Determination of bile acids in human serum by on-line restricted access material-ultra high-performance liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615
Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal: Journal of medicinal chemistry 20080612
Title: Bile acid levels are increased in the liver of patients with steatohepatitis.
Journal: European journal of gastroenterology & hepatology 20080601
Title: Effect of coadsorbent on the photovoltaic performance of zinc pthalocyanine-sensitized solar cells.
Journal: Langmuir : the ACS journal of surfaces and colloids 20080520
Title: [Effects of farnesoid X receptor ligand on the metabolism of bile acids in rats with estrogen-induced intrahepatic cholestasis of pregnancy].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080501
Title: [Analysis of bile acid-related proteins by mass spectrometry].
Journal: Rinsho byori. The Japanese journal of clinical pathology 20080501
Title: Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Journal: Cancer research 20080415
Title: Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia.
Journal: Journal of lipid research 20080401
Title: Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401
Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
Journal: Journal of medicinal chemistry 20080327
Title: Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes.
Journal: FEBS letters 20080319
Title: Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.
Journal: The Biochemical journal 20080301
Title: Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics.
Journal: Methods and findings in experimental and clinical pharmacology 20080301
Title: Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.
Journal: Cancer letters 20080218
Title: FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.
Journal: Cardiovascular research 20080201
Title: Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.
Journal: British journal of pharmacology 20080201
Title: Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR.
Journal: Journal of hepatology 20080201
Title: Systematic studies on the paracellular permeation of model permeants and oligonucleotides in the rat small intestine with chenodeoxycholate as enhancer.
Journal: Journal of pharmaceutical sciences 20080101
Title: The use of High Performance Thin-Layer Chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage.
Journal: Journal of pharmacological and toxicological methods 20080101
Title: Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening.
Journal: Analytical chemistry 20080101
Title: Clostridium scindens baiCD and baiH genes encode stereo-specific 7alpha/7beta-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductases.
Journal: Biochimica et biophysica acta 20080101
Title: Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model.
Journal: Molecular systems biology 20080101
Title: Role of sulphated polysaccharides from Sargassum Wightii in Cyclosporine A-induced oxidative liver injury in rats.
Journal: BMC pharmacology 20080101
Title: Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro.
Journal: Nutrition and cancer 20080101
Title: Peroxisome proliferator-activated receptor alpha activates cyclooxygenase-2 gene transcription through bile acid transport in human colorectal cancer cell lines.
Journal: Journal of gastroenterology 20080101
Title: An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution.
Journal: BMC evolutionary biology 20080101
Title: Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoter.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
Title: Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats.
Journal: European journal of drug metabolism and pharmacokinetics 20080101
Title: Influence of the semisynthetic bile acid (MKC) on the ileal permeation of gliclazide in healthy and diabetic rats.
Journal: Pharmacological reports : PR 20080101
Title: N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta.
Journal: BMC cell biology 20080101
Title: Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes.
Journal: Molecular systems biology 20080101
Title: Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion.
Journal: BMC gastroenterology 20080101
Title: The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes.
Journal: European journal of drug metabolism and pharmacokinetics 20080101
Title: Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells.
Journal: BMC cancer 20080101
Title: Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry.
Journal: Analytical chemistry insights 20080101
Title: Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome.
Journal: Clinical and experimental gastroenterology 20080101
Title: Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.
Journal: Clinical and experimental gastroenterology 20080101
Title: Regulation of hepatic bile acid transporters Ntcp and Bsep expression.
Journal: Biochemical pharmacology 20071203
Title: Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15alpha-hydroxylithocholic acid.
Journal: Journal of lipid research 20071201
Title: Chenodeoxycholic acid suppresses the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317.
Journal: Journal of lipid research 20071201
Title: Regulation of human liver delta-aminolevulinic acid synthase by bile acids.
Journal: Hepatology (Baltimore, Md.) 20071201
Title: Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20071201
Title: Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids.
Journal: Journal of medicinal chemistry 20071129
Title: p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis.
Journal: The Journal of biological chemistry 20071123
Title: Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR.
Journal: Biochemistry 20071106
Title: Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment.
Journal: Chemosphere 20071101
Title: COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma.
Journal: Gut 20071101
Title: Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis.
Journal: Gynecologic oncology 20071101
Title: Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress.
Journal: Molecular pharmacology 20071101
Title: Exposure of airway epithelium to bile acids associated with gastroesophageal reflux symptoms: a relation to transforming growth factor-beta1 production and fibroblast proliferation.
Journal: Chest 20071101
Title: Protective effect of n-3 polyunsaturated fatty acid on primary culture of rat hepatocytes.
Journal: Journal of gastroenterology and hepatology 20071101
Title: Perinatal bile acid metabolism: bile acid analysis of meconium of preterm and full-term infants.
Journal: Journal of gastroenterology 20071101
Title: Beneficial effects of hydrocortisone in induced acute pancreatitis of rats.
Journal: Chinese medical journal 20071020
Title: Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters.
Journal: World journal of gastroenterology 20071007
Title: NMR-based modeling and binding studies of a ternary complex between chicken liver bile acid binding protein and bile acids.
Journal: Proteins 20071001
Title: Dihydroxy bile acids increase mucosal permeability and bacterial uptake in human colon biopsies.
Journal: Scandinavian journal of gastroenterology 20071001
Title: A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma.
Journal: Cancer research 20071001
Title: Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5.
Journal: Journal of medicinal chemistry 20070906
Title: The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070901
Title: Role of bile bacteria in gallbladder carcinoma.
Journal: Hepato-gastroenterology 20070901
Title: Cerebrotendinous xanthomatosis: a treatable cause of metabolic ataxia.
Journal: The Journal of the Association of Physicians of India 20070901
Title: Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR.
Journal: World journal of gastroenterology 20070821
Title: [Cerebrotendinous xanthomatosis].
Journal: Deutsche medizinische Wochenschrift (1946) 20070729
Title: Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).
Journal: The Journal of biological chemistry 20070706
Title: Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.
Journal: Pflugers Archiv : European journal of physiology 20070701
Title: Human cecal bile acids: concentration and spectrum.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: Rifampicin-induced CYP3A4 activation in CTX patients cannot replace chenodeoxycholic acid treatment.
Journal: Biochimica et biophysica acta 20070701
Title: Synthetic organic chemistry based on small ring compounds.
Journal: Chemical & pharmaceutical bulletin 20070701
Title: Cerebrotendinous xanthomatosis in a Saudi Arabian family-genotyping and long-term follow-up.
Journal: Saudi medical journal 20070701
Title: Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.
Journal: World journal of gastroenterology 20070614
Title: Bile acids and lipoprotein metabolism: effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression.
Journal: Biochemical and biophysical research communications 20070608
Title: Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis.
Journal: Journal of lipid research 20070601
Title: In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue.
Journal: Molecular endocrinology (Baltimore, Md.) 20070601
Title: Crystal structure of chenodeoxycholic acid, ursodeoxycholic acid and their two 3beta,7alpha- and 3beta,7beta-dihydroxy epimers.
Journal: Steroids 20070601
Title: Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.
Journal: PLoS pathogens 20070601
Title: Can pigment gallstones be induced by biliary stricture and prevented by medicine in Guinea pigs?
Journal: World journal of gastroenterology 20070521
Title: On the mechanism of cerebral accumulation of cholestanol in patients with cerebrotendinous xanthomatosis.
Journal: Journal of lipid research 20070501
Title: Internalization of PrP106-126 by the formyl-peptide-receptor-like-1 in glial cells.
Journal: Journal of neurochemistry 20070501
Title: Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist.
Journal: Bioorganic & medicinal chemistry 20070401
Title: Non-invasive analysis of gallbladder bile composition in cynomolgus monkeys using in vivo 1H magnetic resonance spectroscopy.
Journal: Biochimica et biophysica acta 20070401
Title: A novel chenodeoxycholic derivative HS-1200 enhances radiation-induced apoptosis in MCF-7 cells.
Journal: Oncology reports 20070401
Title: Why bile acid glucuronidation is a minor pathway for conjugation of endogenous bile acids in man.
Journal: Hepatology (Baltimore, Md.) 20070401
Title: Coordinated defence and the liver.
Journal: Clinical medicine (London, England) 20070401
Title: Acquisition of resistance to butyrate induces resistance to luminal components and other types of stress in human colon adenocarcinoma cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070301
Title: Glycochenodeoxycholate (GCDC) inhibits cytokine induced iNOS expression in rat hepatocytes.
Journal: The Journal of surgical research 20070301
Title: Enzymes in the conversion of cholesterol into bile acids.
Journal: Current molecular medicine 20070301
Title: [Preparation and antitussive, expectorant and antiasthmatic activities of verticinone-bile acids salts].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070301
Title: Bile acid-mediated thrombospondin-1 induction in hepatocytes leads to transforming growth factor-beta-dependent hepatic stellate cell activation.
Journal: Biochemical and biophysical research communications 20070223
Title: LC/ESI-tandem mass spectrometric determination of bile acid 3-sulfates in human urine 3beta-Sulfooxy-12alpha-hydroxy-5beta-cholanoic acid is an abundant nonamidated sulfate.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201
Title: Analysis of bile acid-induced regulation of FXR target genes in human liver slices.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20070201
Title: Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole.
Journal: Oncogene 20070111
Title: Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070101
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis.
Journal: Chemical & pharmaceutical bulletin 20070101
Title: Removal of bile acids by two different extracorporeal liver support systems in acute-on-chronic liver failure.
Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20070101
Title: An improved high throughput protein-protein interaction assay for nuclear hormone receptors.
Journal: Nuclear receptor signaling 20070101
Title: Bioavailability and hypoglycemic activity of the semisynthetic bile acid salt, sodium 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate, in healthy and diabetic rats.
Journal: European journal of drug metabolism and pharmacokinetics 20070101
Title: A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model.
Journal: Molecular systems biology 20070101
Title: Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids.
Journal: PloS one 20070101
Title: Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress.
Journal: Redox report : communications in free radical research 20070101
Title: Biomarker discovery in animal health and disease: the application of post-genomic technologies.
Journal: Biomarker insights 20070101
Title: Dietary chitosan enhances hepatic CYP7A1 activity and reduces plasma and liver cholesterol concentrations in diet-induced hypercholesterolemia in rats.
Journal: Nutrition research and practice 20070101
Title: Bile acid analysis in biliary tract cancer.
Journal: Yonsei medical journal 20061231
Title: Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase.
Journal: Journal of lipid research 20061201
Title: Chenodeoxycholic acid and taurochenodexycholic acid induce anti-apoptotic cIAP-1 expression in human hepatocytes.
Journal: Journal of gastroenterology and hepatology 20061201
Title: Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.
Journal: Journal of internal medicine 20061201
Title: Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids.
Journal: Current cancer drug targets 20061201
Title: Decreased glucagon responsiveness by bile acids: a role for protein kinase Calpha and glucagon receptor phosphorylation.
Journal: Endocrinology 20061101
Title: Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061101
Title: Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver.
Journal: Hepatology (Baltimore, Md.) 20061101
Title: The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo.
Journal: Molecular pharmacology 20061001
Title: Presenile cataract: consider cholestanol.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20061001
Title: The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone.
Journal: Endocrinology 20060901
Title: Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level.
Journal: American journal of physiology. Cell physiology 20060901
Title: Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit.
Journal: Journal of lipid research 20060901
Title: ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids.
Journal: The Journal of steroid biochemistry and molecular biology 20060901
Title: Expression and significance of ICAM-1 and its counter receptors LFA-1 and Mac-1 in experimental acute pancreatitis of rats.
Journal: World journal of gastroenterology 20060821
Title: Chenodeoxycholic acid stimulates the progression of human esophageal cancer cells: A possible mechanism of angiogenesis in patients with esophageal cancer.
Journal: International journal of cancer 20060815
Title: Identification of a lead pharmacophore for the development of potent nuclear receptor modulators as anticancer and X syndrome disease therapeutic agents.
Journal: Bioorganic & medicinal chemistry letters 20060815
Title: Suppression of bile acid synthesis by thyroid hormone in primary human hepatocytes.
Journal: World journal of gastroenterology 20060807
Title: Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38.
Journal: American journal of physiology. Heart and circulatory physiology 20060801
Title: Bile acids stimulate PKCalpha autophosphorylation and activation: role in the attenuation of prostaglandin E1-induced cAMP production in human dermal fibroblasts.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060801
Title: Influence of Verapamil and Cyclosporin A on bile acid metabolism and transport in rat liver slices.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060801
Title: Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum.
Journal: The Journal of pharmacy and pharmacology 20060801
Title: Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.
Journal: Drug metabolism and pharmacokinetics 20060801
Title: A simple and general strategy for the design of fluorescent cation sensor beads.
Journal: Organic letters 20060720
Title: Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives.
Journal: Journal of medicinal chemistry 20060713
Title: Biliary lipid output in the early stage of acute liver failure induced by 90% hepatectomy in the rat.
Journal: The Journal of surgical research 20060701
Title: Identification of a novel bile acid in swans, tree ducks, and geese: 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid.
Journal: Journal of lipid research 20060701
Title: Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.
Journal: Pharmaceutical research 20060701
Title: Chemical fingerprinting of Shexiang Baoxin Pill and simultaneous determination of its major constituents by HPLC with evaporative light scattering detection and electrospray mass spectrometric detection.
Journal: Chemical & pharmaceutical bulletin 20060701
Title: Effects of chenodeoxycholic acid and deoxycholic acid on cholesterol absorption and metabolism in humans.
Journal: Translational research : the journal of laboratory and clinical medicine 20060701
Title: Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: preparation of FXR and PPAR ligands.
Journal: Bioorganic & medicinal chemistry letters 20060615
Title: Determination of three bile acids in artificial Calculus Bovis and its medicinal preparations by micellar electrokinetic capillary electrophoresis.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606
Title: Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060601
Title: Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy.
Journal: Journal of hepatology 20060601
Title: Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.
Journal: Journal of lipid research 20060601
Title: Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus: seasonal changes.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060601
Title: Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells.
Journal: Hepatology (Baltimore, Md.) 20060601
Title: Single-step analysis of individual conjugated bile acids in human bile using 1H NMR spectroscopy.
Journal: Lipids 20060601
Title: Bile acid promotes the proliferation of squamous cell carcinoma of the esophagus, independent of its inducing COX-2 expression.
Journal: The Journal of surgical research 20060501
Title: The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha.
Journal: The Journal of pharmacology and experimental therapeutics 20060501
Title: Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Pharmacophore model for bile acids recognition by the FPR receptor.
Journal: Journal of computer-aided molecular design 20060501
Title: Bile acid-mediated induction of cyclooxygenase-2 and Mcl-1 in hepatic stellate cells.
Journal: Biochemical and biophysical research communications 20060421
Title: Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid.
Journal: Biotechnology and bioengineering 20060420
Title: Could steroids mask the diagnosis of cerebrotendinous xanthomatosis?
Journal: Journal of the neurological sciences 20060415
Title: The region of CQQQKPQRRP of PGC-1alpha interacts with the DNA-binding complex of FXR/RXRalpha.
Journal: Biochemical and biophysical research communications 20060414
Title: NMR dynamic studies suggest that allosteric activation regulates ligand binding in chicken liver bile acid-binding protein.
Journal: The Journal of biological chemistry 20060407
Title: 11Beta-hydroxysteroid dehydrogenase type 2 and the regulation of surfactant protein A by dexamethasone metabolites.
Journal: American journal of physiology. Endocrinology and metabolism 20060401
Title: Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters.
Journal: American journal of physiology. Endocrinology and metabolism 20060401
Title: Bile acid profiles by capillary electrophoresis in intrahepatic cholestasis of pregnancy.
Journal: Clinical science (London, England : 1979) 20060401
Title: Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20060401
Title: Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.
Journal: The Journal of nutrition 20060401
Title: Farnesoid X receptor, hepatocyte nuclear factors 1alpha and 3beta are essential for transcriptional activation of the liver-specific organic anion transporter-2 gene.
Journal: Journal of gastroenterology 20060401
Title: Retrograded tapioca starch prevents ovarian hormone deficiency-induced hypercholesterolemia.
Journal: Journal of nutritional science and vitaminology 20060401
Title: Hepatocyte nuclear factor-4alpha plays pivotal roles in the regulation of mouse carboxylesterase 2 gene transcription in mouse liver.
Journal: Archives of biochemistry and biophysics 20060315
Title: Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells.
Journal: Journal of agricultural and food chemistry 20060308
Title: The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060301
Title: Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: Bile acid transport and metabolism in rat liver slices.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060301
Title: Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060301
Title: 1,25-dihydroxyvitamin D3 and its receptor inhibit the chenodeoxycholic acid-dependent transactivation by farnesoid X receptor.
Journal: The Journal of endocrinology 20060301
Title: Immunoaffinity extraction of a peptide modified by a small molecule.
Journal: Analytical biochemistry 20060215
Title: Nuclear receptors, bile-acid detoxification, and cholestasis.
Journal: Lancet (London, England) 20060211
Title: Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells.
Journal: Circulation research 20060203
Title: A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.
Journal: Journal of lipid research 20060201
Title: Studies of serum and feces bile acids determination by gas chromatography-mass spectrometry.
Journal: Rinsho byori. The Japanese journal of clinical pathology 20060201
Title: Molecular adsorbent recirculating system (MARS) application in liver failure: clinical and hemodepurative results in 22 patients.
Journal: The International journal of artificial organs 20060201
Title: FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine.
Journal: Journal of lipid research 20060101
Title: Micellization of conjugated chenodeoxy- and ursodeoxycholates and solubilization of cholesterol into their micelles: comparison with other four conjugated bile salts species.
Journal: Chemistry and physics of lipids 20060101
Title: Enhancement of DNA topoisomerase I inhibitor-induced apoptosis by ursodeoxycholic acid.
Journal: Molecular cancer therapeutics 20060101
Title: Bile acid metabolism in extrahepatic biliary atresia: lithocholic acid in stored dried blood collected at neonatal screening.
Journal: Upsala journal of medical sciences 20060101
Title: Laparoscopic common bile duct exploration in pregnancy with acute gallstone pancreatitis.
Journal: JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101
Title: Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter.
Journal: Molecular pharmaceutics 20060101
Title: Chenodeoxycholic acid reduce bacterial translocation in sepsis.
Journal: Medical hypotheses 20060101
Title: State-of-art methodology of marine natural products chemistry: structure determination with extremely small sample amounts.
Journal: Progress in molecular and subcellular biology 20060101
Title: Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity.
Journal: BMC cancer 20060101
Title: Cerebrotendinous xanthomatosis: need for early diagnosis.
Journal: Indian journal of dermatology, venereology and leprology 20060101
Title: Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.
Journal: Molecular cancer 20060101
Title: Autosomal recessive cerebellar ataxias.
Journal: Orphanet journal of rare diseases 20060101
Title: Chemical and metabolic transformations of selected bile acids.
Journal: European journal of drug metabolism and pharmacokinetics 20060101
Title: Pharmacology of bile acids and their derivatives: absorption promoters and therapeutic agents.
Journal: European journal of drug metabolism and pharmacokinetics 20060101
Title: Increased serum concentrations of secondary bile salts during cholate feeding are due to coprophagy. A study with wild-type and Atp8b1-deficient mice.
Journal: Molecular pharmaceutics 20060101
Title: [Effect of thromboxane B2 on morphological features of apoptosis in cultured rat hepatocytes exposed to hepatotropic substances].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101
Title: FTF and LRH-1, two related but different transcription factors in human Caco-2 cells: their different roles in the regulation of bile acid transport.
Journal: Biochimica et biophysica acta 20051230
Title: Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine.
Journal: The Journal of biological chemistry 20051223
Title: Effect of a coadsorbent on the performance of dye-sensitized TiO2 solar cells: shielding versus band-edge movement.
Journal: The journal of physical chemistry. B 20051215
Title: Unusual cerebrotendinous xanthomatosis with fronto-temporal dementia phenotype.
Journal: American journal of medical genetics. Part A 20051201
Title: Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20051201
Title: Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.
Journal: The Journal of biological chemistry 20051111
Title: Synthetic bile acid derivatives induce apoptosis through a c-Jun N-terminal kinase and NF-kappaB-dependent process in human cervical carcinoma cells.
Journal: Cancer letters 20051108
Title: Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1.
Journal: Biochemical and biophysical research communications 20051104
Title: Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice.
Journal: Biochemical and biophysical research communications 20051028
Title: Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis.
Journal: The Journal of pharmacology and experimental therapeutics 20051001
Title: 1H and 13C NMR characterization and stereochemical assignments of bile acids in aqueous media.
Journal: Lipids 20051001
Title: Impaired proximal colonic motor response to rectal mechanical and chemical stimulation in obstructed defecation.
Journal: Diseases of the colon and rectum 20050901
Title: VPAC1 expression is regulated by FXR agonists in the human gallbladder epithelium.
Journal: Hepatology (Baltimore, Md.) 20050901
Title: Downregulation of TACO gene transcription restricts mycobacterial entry/survival within human macrophages.
Journal: FEMS microbiology letters 20050901
Title: Synthetic chenodeoxycholic acid derivatives inhibit glioblastoma multiform tumor growth in vitro and in vivo.
Journal: International journal of oncology 20050901
Title: Effect of Larrea tridentata (creosote bush) on cholesterol gallstones and bile secretion in hamsters.
Journal: The Journal of pharmacy and pharmacology 20050901
Title: Cerebrotendinous xanthomatosis: possible higher prevalence than previously recognized.
Journal: Archives of neurology 20050901
Title: Bile acid signaling through FXR induces intracellular adhesion molecule-1 expression in mouse liver and human hepatocytes.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050801
Title: A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis.
Journal: The Journal of pharmacology and experimental therapeutics 20050801
Title: The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes.
Journal: Molecular pharmacology 20050801
Title: Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT).
Journal: Pharmaceutical research 20050801
Title: Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid.
Journal: Journal of biochemistry 20050801
Title: Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Serum bile acid profile in women during pregnancy and childbed.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050701
Title: Pretreatment with ursodeoxycholic acid (UDCA) as a novel pharmacological intervention in hepatobiliary scintigraphy.
Journal: Yonsei medical journal 20050630
Title: Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid: role of the farnesoid X receptor.
Journal: Biochemical pharmacology 20050615
Title: The mechanism underlying the contractile effect of a chemotactic peptide, formyl-Met-Leu-Phe on the guinea-pig Taenia coli.
Journal: British journal of pharmacology 20050601
Title: The cell envelope structure and properties of Mycobacterium smegmatis mc(2)155: is there a clue for the unique transformability of the strain?
Journal: Microbiology (Reading, England) 20050601
Title: Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone.
Journal: European journal of pharmacology 20050516
Title: Transient changes in the expression pattern of key enzymes for bile acid synthesis during rat liver regeneration.
Journal: Biochimica et biophysica acta 20050515
Title: Feedback regulation of bile acid synthesis in human liver: importance of HNF-4alpha for regulation of CYP7A1.
Journal: Biochemical and biophysical research communications 20050506
Title: Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis.
Journal: The Journal of pharmacology and experimental therapeutics 20050501
Title: The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids.
Journal: Molecular pharmacology 20050501
Title: Cerebrotendinous xanthomatosis: a treatable ataxia.
Journal: Neurology 20050426
Title: Bile acids induce MUC2 overexpression in human colon carcinoma cells.
Journal: Cancer 20050415
Title: Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050401
Title: Chemical synthesis of 24-beta-D-galactopyranosides of bile acids: a new type of bile acid conjugates in human urine.
Journal: Chemistry and physics of lipids 20050401
Title: Inhibition of hepatocyte growth factor production in human fibroblasts by ursodeoxycholic acid.
Journal: Biological & pharmaceutical bulletin 20050401
Title: Usefulness of combined measurement of serum bile acids and ferritin as additional prognostic markers to predict failure to reach sustained response to antiviral treatment in chronic hepatitis C.
Journal: Journal of gastroenterology and hepatology 20050401
Title: Increasing ursodeoxycholic acid in the enterohepatic circulation of pigs through the administration of living bacteria.
Journal: The British journal of nutrition 20050401
Title: Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance.
Journal: Journal of lipid research 20050301
Title: Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis.
Journal: Metabolism: clinical and experimental 20050301
Title: A new drug carrier, Nalpha-deoxycholyl-L: -lysyl-methylester, for enhancing insulin absorption in the intestine.
Journal: Diabetologia 20050301
Title: Bile-induced laryngitis: is there a basis in evidence?
Journal: The Annals of otology, rhinology, and laryngology 20050301
Title: Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis.
Journal: Journal of lipid research 20050201
Title: Species-specific mechanisms for cholesterol 7alpha-hydroxylase (CYP7A1) regulation by drugs and bile acids.
Journal: Archives of biochemistry and biophysics 20050201
Title: Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Journal: World journal of gastroenterology 20050107
Title: Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050101
Title: Expression of macrophage migration inhibitory factor in esophageal squamous cell carcinoma and effects of bile acids and NSAIDs.
Journal: Carcinogenesis 20050101
Title: Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative.
Journal: Journal of lipid research 20050101
Title: Bile acid induced gene expression in LT97 colonic adenoma cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101
Title: FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050101
Title: Esophageal visceral sensitivity to bile salts in patients with functional heartburn and in healthy control subjects.
Journal: Digestive diseases and sciences 20050101
Title: [Differential approach to detection and treatment of cholelithiasis in outpatient conditions].
Journal: Terapevticheskii arkhiv 20050101
Title: Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts.
Journal: Anticancer research 20050101
Title: Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).
Journal: Nuclear receptor 20050101
Title: Polymorphism in the coding part of the sterol 12alpha-hydroxylase gene does not explain the marked differences in the ratio of cholic acid and chenodeoxycholic acid in human bile.
Journal: Scandinavian journal of clinical and laboratory investigation 20050101
Title: Inherited cholesterol lipidosis: cerebrotendinous xanthomatosis (van Bogaert Scherer Epstein disease). A clinicopathological study.
Journal: Clinical neuropathology 20050101
Title: Effects of a 3-mo consumption of short-chain fructo-oligosaccharides on parameters of colorectal carcinogenesis in patients with or without small or large colorectal adenomas.
Journal: Nutrition and cancer 20050101
Title: Effect of bile acids on butyrate-sensitive and -resistant human colon adenocarcinoma cells.
Journal: Nutrition and cancer 20050101
Title: Determination of underivatised sterols and bile acid trimethyl silyl ether methyl esters by gas chromatography-mass spectrometry-single ion monitoring in faeces.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Title: Effects of bile acids on proliferation and production of proteinase activity of Uronema marinum (Ciliophora: Scuticociliatida).
Journal: Diseases of aquatic organisms 20041213
Title: Megalin and cubilin expression in gallbladder epithelium and regulation by bile acids.
Journal: Journal of lipid research 20041201
Title: Farnesoid X receptor represses hepatic lipase gene expression.
Journal: Journal of lipid research 20041101
Title: The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis.
Journal: Gastroenterology 20041101
Title: Multidrug resistance3 is in situ detected in the liver of patients with primary biliary cirrhosis, and induced in human hepatoma cells by bezafibrate.
Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20041101
Title: Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4.
Journal: The Journal of biological chemistry 20041029
Title: Effects of meal frequency and high-fibre rye-bread diet on glucose and lipid metabolism and ileal excretion of energy and sterols in ileostomy subjects.
Journal: European journal of clinical nutrition 20041001
Title: Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16.
Journal: PLoS biology 20041001
Title: Normalisation of serum cholestanol concentration in a patient with cerebrotendinous xanthomatosis by combined treatment with chenodeoxycholic acid, simvastatin and LDL apheresis.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001
Title: The nuclear bile acid receptor FXR is activated by PGC-1alpha in a ligand-dependent manner.
Journal: The Biochemical journal 20040915
Title: Bioconversion of 3beta-hydroxy-5-cholenoic acid into chenodeoxycholic acid by rat brain enzyme systems.
Journal: Journal of lipid research 20040901
Title: The farnesoid X receptor: a novel drug target?
Journal: Expert opinion on investigational drugs 20040901
Title: Ursodeoxycholate/Sulindac combination treatment effectively prevents intestinal adenomas in a mouse model of polyposis.
Journal: Gastroenterology 20040901
Title: DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.
Journal: Cancer letters 20040830
Title: Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid.
Journal: Journal of medicinal chemistry 20040826
Title: Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor.
Journal: Journal of lipid research 20040801
Title: Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets.
Journal: DNA and cell biology 20040801
Title: Synthetic bile acid derivatives inhibit cell proliferation and induce apoptosis in HT-29 human colon cancer cells.
Journal: International journal of oncology 20040701
Title: Cyclosporine A-induced reduction of bile salt synthesis associated with increased plasma lipids in children after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040701
Title: Bile acid-induced negative feedback regulation of the human ileal bile acid transporter.
Journal: Hepatology (Baltimore, Md.) 20040701
Title: [Menthol in the adjuvant treatment of gallbladder stones fragmented by ESWL as an option for reducing doses of urso- and chenodeoxycholic acid].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20040615
Title: Epimerization of chenodeoxycholic acid to ursodeoxycholic acid by Clostridium baratii isolated from human feces.
Journal: FEMS microbiology letters 20040601
Title: Effect of chenodeoxycholic acid on 11beta-hydroxysteroid dehydrogenase in various target tissues.
Journal: Metabolism: clinical and experimental 20040601
Title: Short-step synthesis of chenodiol from stigmasterol.
Journal: Bioscience, biotechnology, and biochemistry 20040601
Title: [Cerebrotendinous xanthomatosis--a treatable metabolic disorder].
Journal: Der Nervenarzt 20040601
Title: The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer.
Journal: Digestive diseases and sciences 20040601
Title: Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells.
Journal: Life sciences 20040521
Title: The farnesoid X receptor induces very low density lipoprotein receptor gene expression.
Journal: FEBS letters 20040521
Title: Ion-selective electrodes based on molecular tweezer-type neutral carriers.
Journal: Talanta 20040510
Title: Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501
Title: Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis.
Journal: Metabolism: clinical and experimental 20040501
Title: [Studies on mechanism of antiasthmatic and anti-inflammatory actions of CDCA].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040401
Title: The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion.
Journal: The Journal of biological chemistry 20040305
Title: Bile acids induce cyclooxygenase-2 expression in human pancreatic cancer cell lines.
Journal: Carcinogenesis 20040301
Title: [Studies on antitussive, antiasthmatic and expectorant action of chenodeoxycholine acid].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040301
Title: Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene.
Journal: The Journal of biological chemistry 20040227
Title: Serum bile acids and risk factors for colorectal cancer.
Journal: British journal of cancer 20040209
Title: Presence of protein-bound unconjugated bile acids in the cytoplasmic fraction of rat brain.
Journal: Journal of lipid research 20040201
Title: Cerebrotendinous xanthomatosis: clinical course, genotypes and metabolic backgrounds.
Journal: Clinical and investigative medicine. Medecine clinique et experimentale 20040201
Title: Increased acyclovir oral bioavailability via a bile acid conjugate.
Journal: Molecular pharmaceutics 20040112
Title: Facile synthesis, aggregation behavior, and cholesterol solubilization ability of avicholic acid.
Journal: Organic letters 20040108
Title: Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation.
Journal: Journal of lipid research 20040101
Title: Cross-resistance to antibiotics of Escherichia coli adapted to benzalkonium chloride or exposed to stress-inducers.
Journal: Journal of applied microbiology 20040101
Title: Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.
Journal: Lipids in health and disease 20040101
Title: 3Alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator.
Journal: Polish journal of pharmacology 20040101
Title: Comparison among fecal secondary bile acid levels, fecal microbiota and Clostridium scindens cell numbers in Japanese.
Journal: Microbiology and immunology 20040101
Title: Enhanced susceptibility of LDL to oxidative modification in a CTX patient:- role of chenodeoxycholic acid in xanthoma formation.
Journal: Journal of atherosclerosis and thrombosis 20040101
Title: T0901317 is a dual LXR/FXR agonist.
Journal: Molecular genetics and metabolism 20040101
Title: Farnesoid X receptor activates transcription of the phospholipid pump MDR3.
Journal: The Journal of biological chemistry 20031219
Title: Combined treatment with LDL-apheresis, chenodeoxycholic acid and HMG-CoA reductase inhibitor for cerebrotendinous xanthomatosis.
Journal: Journal of the neurological sciences 20031215
Title: Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules.
Journal: Bioorganic & medicinal chemistry letters 20031215
Title: Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Journal: The Journal of clinical investigation 20031201
Title: In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association.
Journal: The Journal of steroid biochemistry and molecular biology 20031201
Title: Impairment of blood rheology by cholestatic jaundice in human beings.
Journal: The Journal of laboratory and clinical medicine 20031201
Title: Cloning and characterization of the NAD-dependent 7alpha-Hydroxysteroid dehydrogenase from Bacteroides fragilis.
Journal: Current microbiology 20031201
Title: Orphan nuclear receptor Nur77 translocates to mitochondria in the early phase of apoptosis induced by synthetic chenodeoxycholic acid derivatives in human stomach cancer cell line SNU-1.
Journal: Annals of the New York Academy of Sciences 20031201
Title: Micelle formation of sodium chenodeoxycholate and solubilization into the micelles: comparison with other unconjugated bile salts.
Journal: Biochimica et biophysica acta 20031115
Title: Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101
Title: Bile acid composition in snake bile juice and toxicity of snake bile acids to rats.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031101
Title: Metabolic changes in Clostridium absonum ATCC 27555 accompanying induction of epimerization of a primary bile acid.
Journal: Current microbiology 20031101
Title: Ligand-binding domain of farnesoid X receptor (FXR) had the highest sensitivity and activity among FXR variants in a fluorescence-based assay.
Journal: Lipids 20031101
Title: Gallstones - approach to medical management.
Journal: MedGenMed : Medscape general medicine 20031015
Title: Steroid ring hydroxylation patterns govern cooperativity in human bile acid binding protein.
Journal: Biochemistry 20031014
Title: Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy.
Journal: Gut 20031001
Title: Inhibition of the rat hepatic microsomal flurbiprofen acyl glucuronidation by bile acids.
Journal: Journal of pharmaceutical sciences 20031001
Title: Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor.
Journal: Hepatology (Baltimore, Md.) 20031001
Title: Biliary diversion for progressive familial intrahepatic cholestasis: improved liver morphology and bile acid profile.
Journal: Gastroenterology 20031001
Title: Apoptosis and modulation of cell cycle control by synthetic derivatives of ursodeoxycholic acid and chenodeoxycholic acid in human prostate cancer cells.
Journal: Cancer letters 20030925
Title: The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity.
Journal: Molecular endocrinology (Baltimore, Md.) 20030901
Title: Cerebrotendinous xanthomatosis: clinical manifestations, diagnostic criteria, pathogenesis, and therapy.
Journal: Journal of child neurology 20030901
Title: Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha).
Journal: Gene 20030814
Title: Human kininogen gene is transactivated by the farnesoid X receptor.
Journal: The Journal of biological chemistry 20030801
Title: Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.
Journal: Genes & development 20030701
Title: Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR).
Journal: Bioorganic & medicinal chemistry letters 20030602
Title: Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids.
Journal: The Biochemical journal 20030601
Title: Synergistic role of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7alpha-hydroxylase in the pathogenesis of manganese-bilirubin-induced cholestasis in rats.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030601
Title: Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis.
Journal: Hepatology (Baltimore, Md.) 20030601
Title: Bile acid induces cyclo-oxygenase-2 expression in cultured human pharyngeal cells: a possible mechanism of carcinogenesis in the upper aerodigestive tract by laryngopharyngeal reflux.
Journal: The Laryngoscope 20030601
Title: FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity.
Journal: Gastroenterology 20030601
Title: Influence of ethinyloestradiol propanolsulphonate on serum bile acids in healthy volunteers.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601
Title: Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter.
Journal: The Journal of biological chemistry 20030530
Title: Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor.
Journal: The Journal of biological chemistry 20030530
Title: Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.
Journal: Metabolism: clinical and experimental 20030501
Title: Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.
Journal: Biochemical and biophysical research communications 20030425
Title: Regression of diaphyseal multiloculated bone cyst in familial steroid dehydrogenase deficiency.
Journal: Journal of pediatric gastroenterology and nutrition 20030401
Title: A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR.
Journal: Molecular cell 20030401
Title: Gum arabic (GA) modifies paracellular water and electrolyte transport in the small intestine.
Journal: Digestive diseases and sciences 20030401
Title: Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding.
Journal: The Journal of biological chemistry 20030321
Title: Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.
Journal: The Journal of biological chemistry 20030321
Title: Inhibitory effects of ursodeoxycholic acid on the induction of nitric oxide synthase in vascular smooth muscle cells.
Journal: European journal of pharmacology 20030319
Title: A G protein-coupled receptor responsive to bile acids.
Journal: The Journal of biological chemistry 20030314
Title: Differentiated thermal crystallization from amorphous chenodeoxycholic acid between the ground specimens derived from the polymorphs.
Journal: International journal of pharmaceutics 20030306
Title: Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression.
Journal: Hepatology (Baltimore, Md.) 20030301
Title: Synthetic chenodeoxycholic acid derivative HS-1200-induced apoptosis of p815 mastocytoma cells is augmented by co-treatment with lactacystin.
Journal: Anti-cancer drugs 20030301
Title: Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol.
Journal: Mitochondrion 20030301
Title: Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20030204
Title: Upregulation of the oncogene c-myc in Barrett's adenocarcinoma: induction of c-myc by acidified bile acid in vitro.
Journal: Gut 20030201
Title: Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.
Journal: Biochemical pharmacology 20030201
Title: Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
Journal: Molecular endocrinology (Baltimore, Md.) 20030201
Title: Increase of bile acid production by tacrolimus in the rat liver.
Journal: Transplantation proceedings 20030201
Title: Mitochondrially mediated synergistic cell killing by bile acids.
Journal: Biochimica et biophysica acta 20030120
Title: Influence of breast feeding, and adapted and hydrolyzed formulas on biliary bile acids in newborn guinea pigs.
Journal: Biology of the neonate 20030101
Title: Role of MR imaging in the diagnosis of cerebrotendinous xanthogranulomatosis, case report and review of literature.
Journal: La Radiologia medica 20030101
Title: Taurochenodeoxycholic acid induced biphasic hepatotoxicity in isolated perfused rat liver: roles of Ca2+ and calpain.
Journal: Hepato-gastroenterology 20030101
Title: The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2.
Journal: Oncology reports 20030101
Title: Cholestanol metabolism, molecular pathology, and nutritional implications.
Journal: Journal of medicinal food 20030101
Title: Reproducibility of the serum lipid response to coffee oil in healthy volunteers.
Journal: Nutrition journal 20030101
Title: [Cerebrotendinous xanthomatosis, a treatable metabolic disorder].
Journal: Der Nervenarzt 20021201
Title: [Cerebrotendinous xanthomatosis without tendinous xanthomas: presentation of two cases].
Journal: Neurologia (Barcelona, Spain) 20021201
Title: Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver.
Journal: Biochimica et biophysica acta 20021120
Title: Identification of membrane-type receptor for bile acids (M-BAR).
Journal: Biochemical and biophysical research communications 20021115
Title: Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.
Journal: The Journal of biological chemistry 20021004
Title: Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways.
Journal: Oncogene 20021003
Title: The impact of the absence of glycopeptidolipids on the ultrastructure, cell surface and cell wall properties, and phagocytosis of Mycobacterium smegmatis.
Journal: Microbiology (Reading, England) 20021001
Title: Potential bile acid metabolites. 25. Synthesis and chemical properties of stereoisomeric 3alpha,7alpha,16- and 3alpha,7alpha,15-trihydroxy-5beta-cholan-24-oic acids.
Journal: Chemical & pharmaceutical bulletin 20021001
Title: Mutations in the sterol 27-hydroxylase gene (CYP27A) cause hepatitis of infancy as well as cerebrotendinous xanthomatosis.
Journal: Journal of inherited metabolic disease 20021001
Title: Effect of chenodeoxycholic acid on the toxicity of 5alpha-cyprinol sulfate in rats.
Journal: Toxicology 20020930
Title: Synthesis of [3,4-(13)c(2)]-enriched bile salts as NMR probes of protein-ligand interactions.
Journal: The Journal of organic chemistry 20020920
Title: Regulation of hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and cholesterol 7alpha-hydroxylase mRNAs in human liver.
Journal: The Journal of clinical endocrinology and metabolism 20020901
Title: A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test.
Journal: Steroids 20020901
Title: Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity.
Journal: The Journal of biological chemistry 20020830
Title: 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.
Journal: Journal of medicinal chemistry 20020815
Title: Changes in bile acid composition and effect on cytolytic activity of fecal water by ursodeoxycholic acid administration: a placebo-controlled cross-over intervention trial in healthy volunteers.
Journal: Scandinavian journal of gastroenterology 20020801
Title: Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1.
Journal: The Journal of biological chemistry 20020726
Title: The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate.
Journal: The Journal of biological chemistry 20020719
Title: Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor.
Journal: The Journal of biological chemistry 20020719
Title: Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-kappaB activation.
Journal: European journal of pharmacology 20020712
Title: Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling.
Journal: The Journal of biological chemistry 20020705
Title: On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
Journal: Biochimica et biophysica acta 20020613
Title: A prospective study of serum bile acid concentrations and colorectal cancer risk in post-menopausal women on the island of Guernsey.
Journal: British journal of cancer 20020605
Title: Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor.
Journal: Gastroenterology 20020601
Title: Postprandial changes in serum unconjugated bile acid concentrations in healthy beagles.
Journal: American journal of veterinary research 20020601
Title: Effect of colestimide on absorption of unconjugated bile acids in the rat jejunum.
Journal: Journal of gastroenterology and hepatology 20020601
Title: A natural product that lowers cholesterol as an antagonist ligand for FXR.
Journal: Science (New York, N.Y.) 20020531
Title: Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.
Journal: Gene 20020515
Title: A novel primary bile acid in the Shoebill stork and herons and its phylogenetic significance.
Journal: Journal of lipid research 20020501
Title: Relationship between asymptomatic hypercholanaemia of pregnancy and progesterone metabolism.
Journal: Clinical science (London, England : 1979) 20020501
Title: Immunosuppressive effect of chenodeoxycholic acid on natural killer cell activity in patients with biliary atresia and hepatitis C virus-related liver cirrhosis.
Journal: Digestive diseases and sciences 20020501
Title: Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020501
Title: Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells.
Journal: Bioscience, biotechnology, and biochemistry 20020501
Title: Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20020401
Title: Cerebrotendinous xanthomatosis: a rare disease with diverse manifestations.
Journal: Archives of neurology 20020401
Title: [Treatment of cholestatic liver diseases].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20020315
Title: The proximal colonic motor response to rectal mechanical and chemical stimulation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20020301
Title: Characterization of rat liver bile acid acyl glucuronosyltransferase.
Journal: Steroids 20020301
Title: Unconjugated bile acids modulate adult and neonatal neutrophil chemotaxis induced in vitro by N-formyl-met-leu-phe-peptide.
Journal: Pediatric research 20020301
Title: Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.
Journal: Hepatology (Baltimore, Md.) 20020301
Title: The UDCA dosage deficit: a fate shared with CDCA.
Journal: European journal of gastroenterology & hepatology 20020301
Title: Two novel mutations in the sterol 27-hydroxylase gene causing cerebrotendinous xanthomatosis.
Journal: Clinical genetics 20020301
Title: Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.
Journal: Toxicology letters 20020207
Title: Use of ursodeoxycholic acid in patients with liver disease.
Journal: Current gastroenterology reports 20020201
Title: MALDI-TOF-MS analysis of droplets prepared in an electrodynamic balance: 'wall-less' sample preparation.
Journal: Analytical chemistry 20020201
Title: Guest-responsive fluorescence variations of gamma-cyclodextrins labeled with hetero-functionalized pyrene and tosyl moieties.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020201
Title: Conversion of 7 alpha-hydroxycholesterol to bile acid in human subjects: is there an alternate pathway favoring cholic acid synthesis?
Journal: The Journal of laboratory and clinical medicine 20020201
Title: Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
Journal: The Journal of biological chemistry 20020125
Title: Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.
Journal: Carcinogenesis 20020101
Title: Bile salts modulate chronic ethanol-induced hepatotoxicity.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20020101
Title: Demonstration of a direct stimulatory effect of bile salts on rat colonic epithelial cell proliferation.
Journal: Scandinavian journal of gastroenterology 20020101
Title: Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA.
Journal: Cancer detection and prevention 20020101
Title: Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes.
Journal: Journal of pharmacological and toxicological methods 20020101
Title: Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter.
Journal: The Journal of biological chemistry 20011214
Title: Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids.
Journal: The Journal of biological chemistry 20011214
Title: Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids.
Journal: Gastroenterology 20011201
Title: Effect of bile acids on absorption of nitrendipine in healthy subjects.
Journal: British journal of clinical pharmacology 20011201
Title: Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201
Title: Anti-inflammatory effects of 5-aminosalicylic acid conjugates with chenodeoxycholic acid and ursodeoxycholic acid on carrageenan-induced colitis in guinea-pigs.
Journal: The Journal of pharmacy and pharmacology 20011201
Title: Predominance of human versus rat phenotype in the metabolic pathways for bile acid synthesis by hybrid WIF-B9 cells.
Journal: Biochimica et biophysica acta 20011130
Title: Bile acids regulate RANTES gene expression through its cognate NF-kappaB binding sites.
Journal: Biochemical and biophysical research communications 20011116
Title: Cerebrotendinous xanthomatosis.
Journal: Neurology 20011113
Title: Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression.
Journal: The Journal of biological chemistry 20011109
Title: Reduced activity of 11 beta-hydroxysteroid dehydrogenase in patients with cholestasis.
Journal: The Journal of clinical investigation 20011101
Title: Green tea upregulates the low-density lipoprotein receptor through the sterol-regulated element binding Protein in HepG2 liver cells.
Journal: Journal of agricultural and food chemistry 20011101
Title: Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.
Journal: The Journal of biological chemistry 20011019
Title: Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene.
Journal: Biochemical and biophysical research communications 20011005
Title: Effects of bile acids on the humoral immune response: a mechanistic approach.
Journal: Life sciences 20011005
Title: Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids.
Journal: Molecular endocrinology (Baltimore, Md.) 20011001
Title: Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women.
Journal: The British journal of nutrition 20011001
Title: 3beta-hydroxy-delta5 -C27-steroid dehydrogenase deficiency: diagnosis and treatment.
Journal: Journal of paediatrics and child health 20011001
Title: Cerebrotendinous xanthomatosis: 11-year treatment with chenodeoxycholic acid in five patients. An electrophysiological study.
Journal: Journal of the neurological sciences 20010915
Title: Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.
Journal: Journal of lipid research 20010901
Title: Biliary excretion of tauroursodeoxycholate-3-sulfate in the rat.
Journal: Steroids 20010901
Title: [Cerebrotendinous xanthomatosis].
Journal: Nederlands tijdschrift voor geneeskunde 20010901
Title: External biliary drainage plus bile acid feeding is not equal to internal drainage in preserving the cellular immunity following prolonged obstructive jaundice.
Journal: Digestive diseases and sciences 20010901
Title: Effect of bile acids on formation of azoxymethane-induced aberrant crypt foci in colostomized F344 rat colon.
Journal: Cancer letters 20010828
Title: The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.
Journal: The Journal of biological chemistry 20010817
Title: Cerebrotendinous xanthomatosis.
Journal: Journal of the American Academy of Dermatology 20010801
Title: Cerebrotendinous xanthomatosis presenting as 'chologenic diarrhoea'.
Journal: Acta paediatrica (Oslo, Norway : 1992) 20010701
Title: Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore.
Journal: Biochemical pharmacology 20010601
Title: Bile acid hydrophobicity is correlated with induction of apoptosis and/or growth arrest in HCT116 cells.
Journal: The Biochemical journal 20010601
Title: Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo.
Journal: Gastroenterology 20010601
Title: Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon.
Journal: Digestive diseases and sciences 20010601
Title: Apoptotic activity of novel bile acid derivatives in human leukemic T cells through the activation of caspases.
Journal: International journal of oncology 20010501
Title: Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjects.
Journal: Hepatology (Baltimore, Md.) 20010501
Title: Synthetic bile acid derivatives induce nonapoptotic death of human retinal pigment epithelial cells.
Journal: Current eye research 20010501
Title: Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases.
Journal: Japanese heart journal 20010501
Title: Effects of bile salts and aliphatic ionic surfactants on human lymphocyte proliferation.
Journal: European journal of clinical investigation 20010401
Title: Successful combination therapy--flunarizine, pentoxifylline, and cholestyramine--for spur cell anemia.
Journal: International journal of hematology 20010401
Title: LUV's lipid composition modulates diffusion of bile acids.
Journal: Chemistry and physics of lipids 20010401
Title: Cloning and expression of a pig liver taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21): a novel member of the CYP4A subfamily.
Journal: The Journal of biological chemistry 20010330
Title: Chenodeoxycholic treatment of cerebrotendinous xanthomatosis.
Journal: Neurology 20010313
Title: Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers.
Journal: Hepatology (Baltimore, Md.) 20010301
Title: High-performance liquid chromatographic determination of ursodeoxycholic acid after solid phase extraction of blood serum and detection-oriented derivatization.
Journal: Journal of pharmaceutical and biomedical analysis 20010301
Title: The nuclear receptors FXR and LXRalpha: potential targets for the development of drugs affecting lipid metabolism and neoplastic diseases.
Journal: Current pharmaceutical design 20010301
Title: Hypocholesterolemic effect of bile acid sulfonate analogs in hamsters.
Journal: Biological & pharmaceutical bulletin 20010301
Title: Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid.
Journal: Journal of hepatology 20010301
Title: [3 beta-Hydroxysteroid-delta 5-oxidoreductase/isomerase deficiency].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: [3-oxo-delta 4-steroid 5 beta-reductase deficiency].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: [Cerebrotendinous xanthomatosis].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: [Other antihyperlipidemic drugs with novel mechanism].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells.
Journal: Cancer letters 20010210
Title: Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells.
Journal: Gastroenterology 20010201
Title: Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX.
Journal: Journal of lipid research 20010201
Title: Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria.
Journal: Bioscience reports 20010201
Title: Magnetic resonance imaging and spectroscopic changes in brains of patients with cerebrotendinous xanthomatosis.
Journal: Brain : a journal of neurology 20010101
Title: Ursodeoxycholic acid alone or with chenodeoxycholic acid for dissolution of cholesterol gallstones: a randomized multicentre trial. The British-Italian Gallstone Study group.
Journal: Alimentary pharmacology & therapeutics 20010101
Title: Determination of bile acids in biological fluids by liquid chromatography-electrospray tandem mass spectrometry.
Journal: Journal of lipid research 20010101
Title: [Advances in the diagnosis and treatment of cholelithiasis].
Journal: Terapevticheskii arkhiv 20010101
Title: Cerebrotendinous xanthomatosis in three siblings from a Chinese family.
Journal: Singapore medical journal 20010101
Title: Enzyme immunoassay for conjugated 7alpha-hydroxy-3-oxo-4-cholenoic acid in human urine.
Journal: Journal of immunoassay & immunochemistry 20010101
Title: Suppression of renal disease and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE) by chenodeoxycholic acid.
Journal: Lupus 20010101
Title: Differential modulation of cellular death and survival pathways by conjugated bile acids.
Journal: BMC biochemistry 20010101
Title: Extracorporeal shock wave lithotripsy of gallstones with oral dissolution. Results in course of ten years in Czech Republic in correlation to indication criteria.
Journal: Sbornik lekarsky 20010101
Title: Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20001201
Title: Identification of a chemical tool for the orphan nuclear receptor FXR.
Journal: Journal of medicinal chemistry 20000810
Title: In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I.
Journal: European journal of endocrinology 20000201
Title: Identification of a nuclear receptor for bile acids.
Journal: Science (New York, N.Y.) 19990521
Title: Bile acids: natural ligands for an orphan nuclear receptor.
Journal: Science (New York, N.Y.) 19990521
Title: Endogenous bile acids are ligands for the nuclear receptor FXR/BAR.
Journal: Molecular cell 19990501
Title: Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat.
Journal: Journal of lipid research 19990101
Title: Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
Journal: The American journal of physiology 19980101
Title: Triterpenes as potential dimerization inhibitors of HIV-1 protease.
Journal: Biochemical and biophysical research communications 19961014
Title: Bile acids produce a generalized reduction of the catalytic activity of cytochromes P450 and other hepatic microsomal enzymes in vitro: relevance to drug metabolism in experimental cholestasis.
Journal: Journal of gastroenterology and hepatology 19960901
Title: Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids.
Journal: Carcinogenesis 19960301
Title: Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
Journal: European journal of gastroenterology & hepatology 19960301
Title: Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.
Journal: The Biochemical journal 19960115
Title: Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes.
Journal: The Biochemical journal 19950115
Title: Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.
Journal: Journal of lipid research 19931101
Title: cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.
Journal: The Journal of biological chemistry 19930515
Title: Oral and contact dissolution of gallstones.
Journal: American journal of surgery 19930401
Title: Promotion of hepatocellular foci in female rats by chenodeoxycholic acid.
Journal: Carcinogenesis 19910101
Title: Benign recurrent intrahepatic cholestasis: altered bile acid metabolism.
Journal: Gastroenterology 19890801
Title: Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro.
Journal: Journal of acquired immune deficiency syndromes 19890101
Title: [Promoting effect of bile acids on gastric carcinogenesis induced by MNNG in rats].
Journal: Nihon Geka Gakkai zasshi 19890101
Title: [Effect of bile and bile acids on monoamine oxidase and acetylcholinesterase activity in the jejunum of rabbits, guinea pigs and swine].
Journal: Polskie archiwum weterynaryjne 19870101
Title: Evidence for an ordered reaction mechanism for bile salt: 3'phosphoadenosine-5'-phosphosulfate: sulfotransferase from rhesus monkey liver that catalyzes the sulfation of the hepatotoxin glycolithocholate.
Journal: Journal of lipid research 19861101
Title: Inhibition of hepatic and extrahepatic glutathione S-transferases by primary and secondary bile acids.
Journal: The Biochemical journal 19860115
Title: Comparative efficacy and side effects of ursodeoxycholic and chenodeoxycholic acids in dissolving gallstones. A double-blind controlled study.
Journal: Gastroenterology 19831201
Title: Early morphologic and enzymatic changes in livers of rats treated with chenodeoxycholic and ursodeoxycholic acids.
Journal: Hepatology (Baltimore, Md.) 19830101
Title: Serum bile acid levels in intrahepatic cholestasis of pregnancy during treatment with phenobarbital or cholestyramine.
Journal: European journal of obstetrics, gynecology, and reproductive biology 19821201
Title: Carcinoma of the gall-bladder in a patient on long-term chenodeoxycholic acid therapy.
Journal: Clinical oncology 19810901
Title: Lack of response to chenodeoxycholic acid in obese and non-obese patients. Role of cholesterol synthesis and possible response to ursodeoxycholic acid.
Journal: Gut 19801201
Title: [Effect of cholestyramine and chenodesoxycholic acid on liver cirrhosis. An experimental study in rats].
Journal: Zeitschrift fur experimentelle Chirurgie 19800401
Title: Hepatic toxicity in the rhesus monkey treated with chenodeoxycholic acid for 6 months: biochemical and ultrastructural studies.
Journal: Gastroenterology 19760101
Title: Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones.
Journal: Gastroenterology 19751001
Title: Measurement of bile acid synthesis by 14CO2: the metabolism of propionyl CoA.
Journal: Steroids 19751001
Title: Toxicity of chenodeoxycholic acid in the rhesus monkey.
Journal: Gastroenterology 19750801
Title: Toxicity of chenodeoxycholic acid in the nonhuman primate.
Journal: Surgery 19750601
Title: Medical treatment of gallstones.
Journal: Southern medical journal 19750101
Title: [Effects of diet on bile secretion].
Journal: Acta medica Austriaca 19750101
Title: Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Bile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding protein.
Journal: Molecular endocrinology (Baltimore, Md.)
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