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475-80-9,MFCD01708574
Catalog No.:AA00D8R6

475-80-9 | 7-HYDROXYARISTOLOCHIC ACID A

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1mg
≥98%
in stock  
$133.00   $93.00
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5mg
≥98%
in stock  
$426.00   $298.00
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10mg
98% by HPLC
in stock  
$759.00   $531.00
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25mg
98% by HPLC
in stock  
$1,535.00   $1,075.00
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50mg
98% by HPLC
in stock  
$2,572.00   $1,800.00
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100mg
98% by HPLC
in stock  
$4,404.00   $3,083.00
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500mg
98% by HPLC
in stock  
$14,081.00   $9,857.00
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1000mg
98% by HPLC
in stock  
$22,494.00   $15,746.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00D8R6
Chemical Name:
7-HYDROXYARISTOLOCHIC ACID A
CAS Number:
475-80-9
Molecular Formula:
C16H9NO6
Molecular Weight:
311.2458
MDL Number:
MFCD01708574
SMILES:
[O-][N+](=O)c1cc2ccccc2c2c1c(cc1c2OCO1)C(=O)O
Properties
Properties
 
Storage:
2-8℃;  

Computed Properties
 
Complexity:
505  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
3.6  

Downstream Synthesis Route

[1]Pailer;Schleppnik[MonatsheftefurChemie,1957,vol.88,p.367,382][MonatsheftefuerChemie,1958,vol.89,p.175Anm.]

[1]Teresa,J.DePascual;Urones,JulioG.;Fernandez,Alvaro[Phytochemistry,1983,vol.22,#12,p.2745-2748]

[1]Krumbiegel;Roth[ArchivderPharmazie,1987,vol.320,#3,p.264-270]

[1]Krumbiegel;Roth[ArchivderPharmazie,1987,vol.320,#3,p.264-270]

Literature

Title: Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.

Journal: Archives of toxicology 20170101

Title: Human bone morphogenetic protein-7 does not counteract aristolochic acid-induced renal toxicity.

Journal: Journal of applied toxicology : JAT 20151201

Title: An exploratory evaluation of the utility of transcriptional and urinary kidney injury biomarkers for the prediction of aristolochic acid-induced renal injury in male rats.

Journal: Veterinary pathology 20140501

Title: Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney.

Journal: Mutation research 20120318

Title: Determination of dissociation constants of aristolochic acid I and II by capillary electrophoresis with carboxymethyl chitosan-coated capillary.

Journal: Talanta 20110715

Title: Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.

Journal: Neuro endocrinology letters 20110101

Title: [Studies on the chemical constituents from the fruit of Aristolochia debilis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801

Title: Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography-tandem mass spectrometry.

Journal: Talanta 20100315

Title: Simple and rapid analysis of aristolochic acid contained in crude drugs and Kampo formulations with solid-phase extraction and HPLC photodiode-array detection.

Journal: Journal of natural medicines 20091001

Title: Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2--a global assessment based on bibliographic sources.

Journal: Journal of ethnopharmacology 20090817

Title: Analysis of aristolochic acids by CE-MS with carboxymethyl chitosan-coated capillary.

Journal: Electrophoresis 20090501

Title: A new approach for the sensitive determination of DNA adduct of aristolochic acid II by using high-performance liquid chromatography with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090401

Title: [Study of pharmacokinetics of aristolochic acid I and II in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

Title: Rapid determination of aristolochic acid I and II in medicinal plants with high sensitivity by cucurbit[7]uril-modifier capillary zone electrophoresis.

Journal: Talanta 20080115

Title: Production, characterization of a monoclonal antibody against aristolochic acid-II and development of its assay system.

Journal: The American journal of Chinese medicine 20080101

Title: [Studies on solid phase extraction method of aristolochic acids and aristololactams in rat urine].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

Title: Selective toxicity of aristolochic acids I and II.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Quantitative determination of aristolochic acid-derived DNA adducts in rats using 32P-postlabeling/polyacrylamide gel electrophoresis analysis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Study on separation of aristolochic acid I and II by micellar electrokinetic capillary chromatography and competition mechanism between SDS and beta-cyclodextrin.

Journal: Electrophoresis 20060201

Title: Aristolochic acids detected in some raw Chinese medicinal herbs and manufactured herbal products--a consequence of inappropriate nomenclature and imprecise labelling?

Journal: Clinical toxicology (Philadelphia, Pa.) 20060101

Title: Rapid determination of aristolochic acid I and II in Aristolochia plants from different regions by beta-cyclodextrin-modified capillary zone electrophoresis.

Journal: Journal of chromatography. A 20040917

Title: An easy and rapid method to determine aristolochic acids I and II with high sensitivity.

Journal: Analytical and bioanalytical chemistry 20040101

Title: Antithrombin activity of some constituents from Origanum vulgare.

Journal: Fitoterapia 20021201

Title: Determination of aristolochic acid I and II in North American species of Asarum and Aristolochia.

Journal: Die Pharmazie 20021001

Title: Xing G, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutat Res. 2012 Mar 18;743(1-2):52-8.

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Tags:475-80-9 Molecular Formula|475-80-9 MDL|475-80-9 SMILES|475-80-9 7-HYDROXYARISTOLOCHIC ACID A