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4771-31-7,MFCD00723503
Catalog No.:AA00D8VQ

4771-31-7 | 4-(Chloromethyl)-2-phenyl-1,3-thiazole

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
95%
in stock  
$112.00   $78.00
- +
1g
95%
in stock  
$261.00   $183.00
- +
5g
95%
in stock  
$1,009.00   $706.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00D8VQ
Chemical Name:
4-(Chloromethyl)-2-phenyl-1,3-thiazole
CAS Number:
4771-31-7
Molecular Formula:
C10H8ClNS
Molecular Weight:
209.6952
MDL Number:
MFCD00723503
SMILES:
ClCc1csc(n1)c1ccccc1
NSC Number:
40038
Properties
Properties
 
BP:
349.2°C at 760 mmHg  
Form:
Solid  
MP:
49 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
159  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
3  

Downstream Synthesis Route

[1]Sharifzadeh,Mohammad;Khademi,HamidReza;Almasirad,Ali;Rezayan,Zahra;Ghayahbashi,MohsenRezayan;Amini,Mohsen[Lettersindrugdesignanddiscovery,2013,vol.10,#9,p.900-905]

[2]Huntress;Pfister[JournaloftheAmericanChemicalSociety,1943,vol.65,p.1667,1669]

[3]Simiti;Farkas[ArchivderPharmazie,1974,vol.307,#2,p.81-88]

[4]Locationinpatent:experimentalpartMahmoodi,Majid;Aliabadi,Alireza;Emami,Saeed;Safavi,Maliheh;Rajabalian,Saeed;Mohagheghi,Mohammad-Ali;Khoshzaban,Ahad;Samzadeh-Kermani,Alireza;Lamei,Navid;Shafiee,Abbas;Foroumadi,Alireza[ArchivderPharmazie,2010,vol.343,#7,p.411-416]

[1]JournaloftheChemicalSociety,1953,p.1740

[1]Chemistryandbiodiversity,2019

[2]HeterocyclicCommunications,2017,vol.23,p.455-460

[3]Patent:WO2015/172196,2015,A1.Locationinpatent:Paragraph0025;00208

[4]JournalofMedicinalChemistry,2016,vol.59,p.9686-9720

[5]Patent:US2018/362450,2018,A1.Locationinpatent:Paragraph0095;0096

[6]JournalofMedicinalChemistry,2014,vol.57,p.3213-3222

[7]Patent:CN103833742,2016,B.Locationinpatent:Paragraph0075;0076;0077

[8]Patent:US2011/311459,2011,A1

[9]Patent:WO2011/160919,2011,A1.Locationinpatent:Page/Pagecolumn65-66

[10]ChemicalBiologyandDrugDesign,2011,vol.78,p.844-852

[11]Patent:CN103833669,2016,B.Locationinpatent:Paragraph0066-0068

[12]Patent:CN103833667,2016,B.Locationinpatent:Paragraph0092-0094

[13]Patent:CN103833670,2016,B.Locationinpatent:Paragraph0100-0103

[14]Lettersindrugdesignanddiscovery,2013,vol.10,p.900-905

[15]Patent:WO2017/184520,2017,A1.Locationinpatent:Page/Pagecolumn41

[16]Patent:WO2015/184011,2015,A2.Locationinpatent:Paragraph0268;0269;0270

[17]Patent:WO2018/200674,2018,A1.Locationinpatent:Page/Pagecolumn83;84

[18]Patent:CN108373476,2018,A.Locationinpatent:Paragraph0329-0333

[19]RecueildesTravauxChimiquesdesPays-Bas,1930,vol.49,p.1066

[20]JournalofMedicinalChemistry,1996,vol.39,p.237-245

[21]Patent:US6063734,2000,A

[22]Patent:WO2008/73929,2008,A1.Locationinpatent:Page/Pagecolumn124

[23]Patent:WO2008/73934,2008,A1.Locationinpatent:Page/Pagecolumn82

[24]JournalofMedicinalChemistry,2008,vol.51,p.4660-4671

[25]Patent:EP1445254,2004,A1.Locationinpatent:Page17

[26]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.2933-2937

[27]ArchivderPharmazie,2010,vol.343,p.411-416

[28]JournalofMolecularCatalysisB:Enzymatic,2013,vol.94,p.88-94

[29]Molecules,2014,vol.19,p.9240-9256

[30]EuropeanJournalofOrganicChemistry,2016,vol.2016,p.1017-1024

[31]Patent:CN106608873,2017,A.Locationinpatent:Paragraph0101;0102;0108

[32]Patent:CN106187937,2016,A.Locationinpatent:Paragraph0109;0111

[33]ChemicalPapers,2017,vol.71,p.2053-2061

[34]JournalofHeterocyclicChemistry,2017,vol.54,p.3395-3402

[35]EuropeanJournalofMedicinalChemistry,2018,vol.149,p.170-181

[36]MedicinalChemistryResearch,2018,vol.27,p.1396-1407

[37]Patent:WO2019/27058,2019,A1.Locationinpatent:Paragraph0278

[38]SyntheticCommunications,2019,vol.49,p.1286-1300

[39]BioorganicandMedicinalChemistry,2019,vol.27,p.3218-3228

[1]BioorganicandMedicinalChemistryLetters,2000,vol.10,p.2041-2044

[2]ArchivderPharmazie,2010,vol.343,p.411-416

[3]JournalofMolecularCatalysisB:Enzymatic,2013,vol.94,p.88-94

[4]Molecules,2014,vol.19,p.9240-9256

[5]Lettersindrugdesignanddiscovery,2013,vol.10,p.900-905

[6]MedicinalChemistryResearch,2018,vol.27,p.1396-1407

[7]Patent:CN108373476,2018,A

[1]JournaloftheAmericanChemicalSociety,1943,vol.65,p.1667,1669

[2]ArchivderPharmazie,1974,vol.307,p.81-88

Literature

Title: Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents.

Journal: Bioinorganic chemistry and applications 20070101

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