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479-92-5,MFCD00053368
Catalog No.:AA003TXH

479-92-5 | Propyphenazone

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Purity
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1g
98%(GC)
in stock  
$24.00   $17.00
- +
5g
98%(GC)
in stock  
$47.00   $33.00
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25g
>98.0%(GC)
in stock  
$74.00   $52.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003TXH
Chemical Name:
Propyphenazone
CAS Number:
479-92-5
Molecular Formula:
C14H18N2O
Molecular Weight:
230.3055
MDL Number:
MFCD00053368
SMILES:
CC(c1c(C)n(n(c1=O)c1ccccc1)C)C
Properties
Properties
 
Form:
Solid  
MP:
88-90°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
340  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
1.7  

Literature

Title: Screening of emerging contaminants and priority substances (2008/105/EC) in reclaimed water for irrigation and groundwater in a volcanic aquifer (Gran Canaria, Canary Islands, Spain).

Journal: The Science of the total environment 20120901

Title: Triple negative breast cancer is associated with an increased risk of residual invasive carcinoma after lumpectomy.

Journal: Cancer 20120815

Title: Transformation of phenazone-type drugs during chlorination.

Journal: Water research 20120501

Title: Flow Cytometry-Assisted Basophil Activation Test as a Safe Diagnostic Tool for Aspirin/NSAID Hypersenstivity.

Journal: Allergy, asthma & immunology research 20120501

Title: Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers.

Journal: Environmental science & technology 20120207

Title: A tale of two polymorphic pharmaceuticals: pyrithyldione and propyphenazone and their 1937 co-crystal patent.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20111125

Title: Hypotension in patients administered indigo carmine containing impurities -A case report-.

Journal: Korean journal of anesthesiology 20111101

Title: Analytical strategy for the confirmatory analysis of the non-steroidal anti-inflammatory drugs firocoxib, propyphenazone, ramifenazone and piroxicam in bovine plasma by liquid chromatography tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20110910

Title: Conformations of antipyrines.

Journal: The journal of physical chemistry. A 20110512

Title: Acute inferior myocardial infarction with low atrial rhythm due to propyphenazone: Kounis syndrome.

Journal: International journal of cardiology 20110505

Title: Evaluation of the reproductive and developmental risks of caffeine.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110401

Title: Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?

Journal: BMC neurology 20110101

Title: Basophil activation test for investigation of IgE-mediated mechanisms in drug hypersensitivity.

Journal: Journal of visualized experiments : JoVE 20110101

Title: VUV photon-induced ionization/dissociation of antipyrine and propyphenazone: mass spectrometric and theoretical insights.

Journal: Journal of mass spectrometry : JMS 20100701

Title: Two-column sequential injection chromatography--new approach for fast and effective analysis and its comparison with gradient elution chromatography.

Journal: Analytica chimica acta 20100523

Title: Effects of propyphenazone and other non-steroidal anti-inflammatory agents on the synthetic and endogenous androgenic anabolic steroids urinary excretion and/or instrumental detection.

Journal: Analytica chimica acta 20100104

Title: The role of organic matter in the removal of emerging trace organic chemicals during managed aquifer recharge.

Journal: Water research 20100101

Title: Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites.

Journal: PloS one 20100101

Title: The characteristics of enriched nitrifier culture in the degradation of selected pharmaceutically active compounds.

Journal: Journal of hazardous materials 20091115

Title: A case of linear immunoglobulin A bullous dermatosis in a patient exposed to sun and an analgesic.

Journal: Clinical therapeutics 20090901

Title: Acute myocardial infarction and Kounis syndrome.

Journal: International journal of cardiology 20090515

Title: Quantification of 4-methylaminoantipyrine, the active metabolite of dipyrone, in human plasma.

Journal: Bioanalysis 20090501

Title: Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment.

Journal: Water research 20090201

Title: Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128

Title: Evaluation of pharmaceuticals and personal care products as water-soluble molecular markers of sewage.

Journal: Environmental science & technology 20080901

Title: Rejection of pharmaceuticals in nanofiltration and reverse osmosis membrane drinking water treatment.

Journal: Water research 20080801

Title: Comprehensive screening and quantification of veterinary drugs in milk using UPLC-ToF-MS.

Journal: Analytical and bioanalytical chemistry 20080701

Title: Determination of caffeine and associated compounds in food, beverages, natural products, pharmaceuticals, and cosmetics by micellar electrokinetic capillary chromatography.

Journal: Journal of chromatographic science 20080201

Title: Treatment of a landfill leachate containing compounds of pharmaceutical origin.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101

Title: Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101

Title: Removal of selected pharmaceuticals and personal care products (PPCPs) and endocrine-disrupting chemicals (EDCs) during sand filtration and ozonation at a municipal sewage treatment plant.

Journal: Water research 20071101

Title: Investigation of the behavior and metabolism of pharmaceutical residues during purification of contaminated ground water used for drinking water supply.

Journal: Chemosphere 20071101

Title: Simultaneous determination of paracetamol, caffeine and propyphenazone in ternary mixtures by micellar electrokinetic capillary chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301

Title: Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor.

Journal: Analytical and bioanalytical chemistry 20070201

Title: Development of a multicommuted flow-through optosensor for the determination of a ternary pharmaceutical mixture.

Journal: Journal of pharmaceutical and biomedical analysis 20070117

Title: Determination of the analgesic components of Spasmomigraine tablet by liquid chromatography with ultraviolet detection.

Journal: Journal of AOAC International 20070101

Title: Development and validation of chemometrics-assisted spectrophotometry and liquid chromatography methods for the simultaneous determination of the active ingredients in two multicomponent mixtures containing chlorpheniramine maleate and phenylpropanolamine hydrochloride.

Journal: Journal of AOAC International 20070101

Title: Long-term comparison of trace organics removal performances between conventional and membrane activated sludge processes.

Journal: Water environment research : a research publication of the Water Environment Federation 20061201

Title: Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment.

Journal: Water research 20061001

Title: Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods.

Journal: Journal of molecular graphics & modelling 20060301

Title: Celosomy is associated with prenatal exposure to cyclooxygenase inhibitors.

Journal: Pharmacological research 20060301

Title: Inhibition of human neutrophil oxidative burst by pyrazolone derivatives.

Journal: Free radical biology & medicine 20060215

Title: Mobility of pharmaceuticals carbamazepine, diclofenac, ibuprofen, and propyphenazone in miscible-displacement experiments.

Journal: Journal of contaminant hydrology 20060201

Title: Dipyrone and aminopyrine are effective scavengers of reactive nitrogen species.

Journal: Redox report : communications in free radical research 20060101

Title: [Abuse pattern of analgesics in chronic daily headache: a study in the general population].

Journal: Revista clinica espanola 20051201

Title: Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.

Journal: Drug safety 20050101

Title: Pharmaceuticals in the river Elbe and its tributaries.

Journal: Chemosphere 20041001

Title: Detection and identification of phenazone-type drugs and their microbial metabolites in ground and drinking water applying solid-phase extraction and gas chromatography with mass spectrometric detection.

Journal: Journal of chromatography. A 20041001

Title: Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041001

Title: Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol.

Journal: Human & experimental toxicology 20040501

Title: Wavelet analysis for the multicomponent determination in a binary mixture of caffeine and propyphenazone in tablets.

Journal: Farmaco (Societa chimica italiana : 1989) 20040401

Title: [Propyphenazone. Pharmacology and use].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20040301

Title: [Two cases of anaphylactic shock after metamizol given during postoperative recovery].

Journal: Revista espanola de anestesiologia y reanimacion 20040301

Title: Transport of pharmaceutically active compounds in saturated laboratory columns.

Journal: Ground water 20040101

Title: Effects of anti-inflammatory drugs on convulsant activity of quinolones: a comparative study of drug interaction between quinolones and anti-inflammatory drugs.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201

Title: Optimization of the RP-HPLC method for multicomponent analgetic drug determination.

Journal: Bollettino chimico farmaceutico 20031101

Title: Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry.

Journal: Chemosphere 20030401

Title: IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.

Journal: The Journal of allergy and clinical immunology 20030401

Title: Dissolution and assaying of multicomponent tablets by chemometric methods using computer-aided spectrophotometer.

Journal: International journal of pharmaceutics 20030116

Title: [Current aspects of the treatment of migraine].

Journal: Likars'ka sprava 20030101

Title: Biological and metabolic study of naproxen-propyphenazone mutual prodrug.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20021101

Title: Drugs and personal care products as ubiquitous pollutants: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea.

Journal: The Science of the total environment 20020805

Title: Advanced fibre optical scanning in thin-layer chromatography for drug identification.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020525

Title: The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis).

Journal: Current medical research and opinion 20020101

Title: Effects of prenatal exposure to combination of acetaminophen, isopropylantipyrine and caffeine on intrauterine development in rats.

Journal: Human & experimental toxicology 20020101

Title: Formation of the knee joint after prenatal propyphenazone (isopropylantipyrine) administration.

Journal: Cells, tissues, organs 20020101

Title: Drug-induced hepatitis with hepatic granuloma due to saridon.

Journal: Journal of gastroenterology 20020101

Title: Determination of neutral pharmaceuticals in wastewater and rivers by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. A 20011214

Title: Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixtures.

Journal: Journal of pharmaceutical and biomedical analysis 20011201

Title: Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.

Journal: Immunopharmacology and immunotoxicology 20011101

Title: Combined effects of acetaminophen, isopropylantipyrine and caffeine on pregnant and nonpregnant liver.

Journal: Human & experimental toxicology 20011101

Title: New method for rapid solid-phase extraction of large-volume water samples and its application to non-target screening of North Sea water for organic contaminants by gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20010330

Title: [Optimal conditions for extraction of 'caffetin' and 'saridon' tablet components from aqueous solutions].

Journal: Sudebno-meditsinskaia ekspertiza 20010101

Title: Autoimmune haemolytic anaemia induced by propyphenazone.

Journal: Vox sanguinis 19980101

Title: Diagnosis of antibody-mediated drug allergy. Pyrazolinone and pyrazolidinedione cross-reactivity relationships.

Journal: Allergy 19871101

Title: Risks of agranulocytosis and aplastic anemia. A first report of their relation to drug use with special reference to analgesics. The International Agranulocytosis and Aplastic Anemia Study.

Journal: JAMA 19861003

Title: [Toxic hemolytic anemia in the newborn infant following ingestion of a phenazone derivative (Cibalgin) via breast milk].

Journal: Zeitschrift fur Geburtshilfe und Perinatologie 19850101

Title: Burdan F, et al. Formation of the knee joint after prenatal propyphenazone (isopropylantipyrine) administration. Cells Tissues Organs. 2002;171(2-3):145-51.

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