Home Deuterated Building Blocks 479077-02-6
479077-02-6,MFCD12195836
Catalog No.:AA00DD06

479077-02-6 | MMPIP

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Purity
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1mg
≥98%
in stock  
$197.00   $138.00
- +
5mg
≥98%
in stock  
$222.00   $155.00
- +
10mg
≥98%
in stock  
$356.00   $249.00
- +
25mg
≥98%
in stock  
$727.00   $509.00
- +
50mg
≥98%
in stock  
$1,415.00   $990.00
- +
100mg
≥98%
in stock  
$2,499.00   $1,749.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DD06
Chemical Name:
MMPIP
CAS Number:
479077-02-6
Molecular Formula:
C19H15N3O3
Molecular Weight:
333.3407
MDL Number:
MFCD12195836
SMILES:
COc1ccc(cc1)c1cc2onc(c2c(=O)n1C)c1ccncc1
Properties
Computed Properties
 
Complexity:
524  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
3  
XLogP3:
2.2  

Literature

Title: Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats.

Journal: Addiction biology 20120301

Title: Effects of a novel metabotropic glutamate receptor 7 negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazonolo[4,5-c]pyridin-4(5H)-one (MMPIP), on the central nervous system in rodents.

Journal: European journal of pharmacology 20100810

Title: Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7.

Journal: Molecular pharmacology 20100301

Title: Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601

Title: In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists.

Journal: The Journal of pharmacology and experimental therapeutics 20071001

Title: Gentaroh Suzuki, et al. In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists. J Pharmacol Exp Ther. 2007 Oct;323(1):147-56.

Title: Paulina Cieślik, et al. Negative Allosteric Modulators of mGlu 7 Receptor as Putative Antipsychotic Drugs. Front Mol Neurosci. 2018 Sep 20;11:316.

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SDS
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