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480-96-6,MFCD00005807
Catalog No.:AA0034F6

480-96-6 | Benzofuroxan

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Purity
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5g
95%
in stock  
$18.00   $13.00
- +
25g
95%
in stock  
$24.00   $17.00
- +
100g
98%
in stock  
$52.00   $36.00
- +
500g
95%
in stock  
$239.00   $167.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034F6
Chemical Name:
Benzofuroxan
CAS Number:
480-96-6
Molecular Formula:
C6H4N2O2
Molecular Weight:
136.1082
MDL Number:
MFCD00005807
SMILES:
[O-][n+]1onc2c1cccc2
NSC Number:
19930
Properties
Properties
 
BP:
246.2°C at 760 mmHg  
Form:
Solid  
MP:
66-69 °C  
Refractive Index:
1.4738 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
131  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
XLogP3:
1.4  

Literature

Title: Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites.

Journal: PloS one 20120101

Title: Synthesis and evaluation of a series of 2-substituted-5-thiopropylpiperazine (piperidine)-1,3,4-oxadiazoles derivatives as atypical antipsychotics.

Journal: PloS one 20120101

Title: Novel benzofuroxan derivatives against multidrug-resistant Staphylococcus aureus strains: design using Topliss' decision tree, synthesis and biological assay.

Journal: Bioorganic & medicinal chemistry 20110815

Title: Synthesis of quinoxaline 1,4-di-N-oxide analogues and crystal structure of 2-carbomethoxy-3-hydroxyquinoxaline-di-N-oxide.

Journal: Molecules (Basel, Switzerland) 20110812

Title: The stepwise Diels-Alder reaction of 4-nitrobenzodifuroxan with Danishefsky's diene.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110627

Title: A small-molecule inhibitor of MDMX activates p53 and induces apoptosis.

Journal: Molecular cancer therapeutics 20110101

Title: Structural relationships in the solid state of the anti-chagas agent (E)-phenylethenylbenzofuroxan.

Journal: Molecular diversity 20101101

Title: o-Benzoquinone dioxime.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Mode of action of nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: is oxidative stress involved?

Journal: Biochemical pharmacology 20100615

Title: Synthesis and pharmacological characterization of a novel nitric oxide-releasing diclofenac derivative containing a benzofuroxan moiety.

Journal: European journal of medicinal chemistry 20100601

Title: Synthesis and anticonvulsant activity of a new series of 1,4-dihydropyridine derivatives.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Anti-trypanosomatid benzofuroxans and deoxygenated analogues: synthesis using polymer-supported triphenylphosphine, biological evaluation and mechanism of action studies.

Journal: European journal of medicinal chemistry 20091201

Title: Cytotoxic, mutagenic and genotoxic effects of new anti-T. cruzi 5-phenylethenylbenzofuroxans. Contribution of phase I metabolites on the mutagenicity induction.

Journal: Toxicology letters 20091028

Title: Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus.

Journal: Bioorganic & medicinal chemistry 20090415

Title: In vivo studies of 5-arylethenylbenzofuroxans in acute murine models of Chagas' disease.

Journal: European journal of medicinal chemistry 20081001

Title: New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Development of a HPLC method for the determination of antichagasic phenylethenylbenzofuroxans and its major synthetic secondary products in the chemical production processes.

Journal: Journal of pharmaceutical and biomedical analysis 20080512

Title: Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives.

Journal: Molecules (Basel, Switzerland) 20080118

Title: In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives.

Journal: Journal of medicinal chemistry 20071129

Title: Synthesis of neutral spin-delocalized electron acceptors for multifunctional materials.

Journal: Organic letters 20071108

Title: Evidence for the intermediacy of Wheland-Meisenheimer complexes in SEAr reactions of aminothiazoles with 4,6-dinitrobenzofuroxan.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies.

Journal: Bioorganic & medicinal chemistry 20051201

Title: Pharmacological properties of furoxans and benzofuroxans: recent developments.

Journal: Mini reviews in medicinal chemistry 20050101

Title: Identification of 2,3-diaminophenazine and of o-benzoquinone dioxime as the major in vitro metabolites of benzofuroxan.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040401

Title: Nonselective inhibition of monoamine oxidases A and B by activators of soluble guanylate cyclase.

Journal: Biochemistry. Biokhimiia 20030901

Title: Sigma-complex formation and oxidative nucleophilic aromatic substitution in 4-nitro-2,1,3-benzoxadiazoles.

Journal: Organic & biomolecular chemistry 20030621

Title: Nitroanilines are the reduction products of benzofuroxan system by oxyhemoglobin (HbO2 2+).

Journal: Farmaco (Societa chimica italiana : 1989) 20011001

Title: Toward an understanding of the furoxan-dinitrosoethylene equilibrium.

Journal: Journal of the American Chemical Society 20010801

Title: [Formations and reactions of aromatic furazan compounds].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010601

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