Home Indole and Oxindoles 487-16-1
487-16-1,MFCD00043581
Catalog No.:AA00DAMQ

487-16-1 | 2-(2-Oxo-1,2-dihydro-3h-indol-3-yliden)-1-hydrazinecarbothioamide

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  • Technical Information
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Technical Information
Catalog Number:
AA00DAMQ
Chemical Name:
2-(2-Oxo-1,2-dihydro-3h-indol-3-yliden)-1-hydrazinecarbothioamide
CAS Number:
487-16-1
Molecular Formula:
C9H8N4OS
Molecular Weight:
220.2510
MDL Number:
MFCD00043581
SMILES:
NC(=S)N/N=C/1\C(=O)Nc2c1cccc2
NSC Number:
721
Properties
Computed Properties
 
Complexity:
283  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
2.1  

Literature

Title: A study on the alkaline hydrolysis of isatin-β-thiosemicarbazone by capillary electrophoresis with enhanced sample loadability.

Journal: Journal of chromatography. A 20120511

Title: Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein.

Journal: Journal of medicinal chemistry 20110825

Title: Isatin-β-thiosemicarbazones as potent herpes simplex virus inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20110401

Title: Synthesis characterization and biological activity study of new schiff and mannich bases and some metal complexes derived from isatin and dithiooxamide.

Journal: Bioinorganic chemistry and applications 20110101

Title: Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.

Journal: PLoS pathogens 20100701

Title: Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells.

Journal: Journal of medicinal chemistry 20090528

Title: In vitro susceptibility of sea lion poxvirus to cidofovir.

Journal: Antiviral research 20081001

Title: Mapping and phenotypic analysis of spontaneous isatin-beta-thiosemicarbazone resistant mutants of vaccinia virus.

Journal: Virology 20070705

Title: A targeted approach to identification of vaccinia virus postreplicative transcription elongation factors: genetic evidence for a role of the H5R gene in vaccinia transcription.

Journal: Virology 20070705

Title: In vitro and in vivo evaluation of isatin-beta-thiosemicarbazone and marboran against vaccinia and cowpox virus infections.

Journal: Antiviral research 20060801

Title: BIOZON: a system for unification, management and analysis of heterogeneous biological data.

Journal: BMC bioinformatics 20060101

Title: Synthesis and evaluation of anti-HIV activity of isatin beta-thiosemicarbazone derivatives.

Journal: Bioorganic & medicinal chemistry letters 20051015

Title: Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents.

Journal: Journal of medicinal chemistry 20050421

Title: An isatin-beta-thiosemicarbazone-resistant vaccinia virus containing a mutation in the second largest subunit of the viral RNA polymerase is defective in transcription elongation.

Journal: The Journal of biological chemistry 20041022

Title: Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.

Journal: Clinical microbiology reviews 20010401

Title: Inhibition of human immunodeficiency virus by N-methylisatin-beta 4':4'-diethylthiosemicarbazone and N-allylisatin-beta-4':4'-diallythiosemicarbazone.

Journal: Antiviral research 19940801

Title: Inhibition of vaccinia virus late protein synthesis by isatin-beta-thiosemicarbazone: characterization and in vitro translation of viral mRNA.

Journal: Virology 19790730

Title: Inactivation of herpes simplex virus by thiosemicarbazones and certain cations.

Journal: Antimicrobial agents and chemotherapy 19740401

Title: Synthesis and antiviral and antibacterial activity of certain N-dialkylaminomethylisatin beta-thiosemicarbazones.

Journal: Journal of medicinal chemistry 19670901

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Tags:487-16-1 Molecular Formula|487-16-1 MDL|487-16-1 SMILES|487-16-1 2-(2-Oxo-1,2-dihydro-3h-indol-3-yliden)-1-hydrazinecarbothioamide