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489402-47-3,MFCD23136017
Catalog No.:AA00DA8L

489402-47-3 | ML213

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$6.00   $4.00
- +
5mg
95%
in stock  
$16.00   $11.00
- +
10mg
95%
in stock  
$24.00   $17.00
- +
25mg
95%
in stock  
$39.00   $28.00
- +
50mg
95%
in stock  
$66.00   $47.00
- +
100mg
95%
in stock  
$111.00   $78.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DA8L
Chemical Name:
ML213
CAS Number:
489402-47-3
Molecular Formula:
C17H23NO
Molecular Weight:
257.3706
MDL Number:
MFCD23136017
SMILES:
O=C(C1CC2CC1CC2)Nc1c(C)cc(cc1C)C
Properties
Computed Properties
 
Complexity:
341  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
3  
XLogP3:
4.2  

Literature

Title: Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener.

Journal: ACS chemical neuroscience 20111019

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Brueggemann LI, et al. Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673. Mol Pharmacol. 2014 Sep;86(3):330-41.

Title: Jepps TA, et al. Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370. Br J Pharmacol. 2014 Oct;171(19):4413-24.

Title: Yu H, et al. Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo.2.1heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. ACS Chem Neurosci. 2011 Oct 19;2(10):572-577.

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SDS
Tags:489402-47-3 Molecular Formula|489402-47-3 MDL|489402-47-3 SMILES|489402-47-3 ML213