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Title: Thymoquinone induces apoptosis in bladder cancer cell via endoplasmic reticulum stress-dependent mitochondrial pathway.
Journal: Chemico-biological interactions 20180825
Title: Improvement of antihyperglycemic activity of nano-thymoquinone in rat model of type-2 diabetes.
Journal: Chemico-biological interactions 20180205
Title: Beneficial effects of TQRF and TQ nano- and conventional emulsions on memory deficit, lipid peroxidation, total antioxidant status, antioxidants genes expression and soluble Aβ levels in high fat-cholesterol diet-induced rats.
Journal: Chemico-biological interactions 20170925
Title: Protective effect of thymoquinone, the active constituent of Nigella sativa fixed oil, against ethanol toxicity in rats.
Journal: Iranian journal of basic medical sciences 20170801
Title: Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease.
Journal: Toxicology letters 20170705
Title: Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.
Journal: Environmental toxicology 20170201
Title: Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury.
Journal: Toxicology letters 20161116
Title: A novel therapeutic application of solid lipid nanoparticles encapsulated thymoquinone (TQ-SLNs) on 3-nitroproponic acid induced Huntington's disease-like symptoms in wistar rats.
Journal: Chemico-biological interactions 20160825
Title: Thymoquinone effectively alleviates lung fibrosis induced by paraquat herbicide through down-regulation of pro-fibrotic genes and inhibition of oxidative stress.
Journal: Environmental toxicology and pharmacology 20160701
Title: The Th1/Th2 paradigm in lambda cyhalothrin-induced spleen toxicity: The role of thymoquinone.
Journal: Environmental toxicology and pharmacology 20160101
Title: Combined effect of microRNA, nutraceuticals and drug on pancreatic cancer cell lines.
Journal: Chemico-biological interactions 20150525
Title: Thymoquinone attenuates Doxorubicin-induced nephrotoxicity in rats: Role of Nrf2 and NOX4.
Journal: Chemico-biological interactions 20141105
Title: Antitubercular and antibacterial activity of quinonoid natural products against multi-drug resistant clinical isolates.
Journal: Phytotherapy research : PTR 20140701
Title: Natural products as topoisomerase II poisons: effects of thymoquinone on DNA cleavage mediated by human topoisomerase IIα.
Journal: Chemical research in toxicology 20140519
Title: Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140301
Title: Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma.
Journal: Toxicology letters 20131023
Title: Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo(a)pyrene.
Journal: Asian Pacific journal of cancer prevention : APJCP 20130101
Title: Thymoquinone blocks lung injury and fibrosis by attenuating bleomycin-induced oxidative stress and activation of nuclear factor Kappa-B in rats.
Journal: Toxicology 20121216
Title: Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation.
Journal: Investigational new drugs 20121201
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Modulation of hepatic drug metabolizing enzymes by dietary doses of thymoquinone in female New Zealand White rabbits.
Journal: Phytotherapy research : PTR 20121101
Title: Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts.
Journal: Investigational new drugs 20121001
Title: Characterization of secondary volatile profiles in Nigella sativa seeds from two different origins using accelerated solvent extraction and gas chromatography-mass spectrometry.
Journal: Biomedical chromatography : BMC 20121001
Title: Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress.
Journal: Molecular and cellular biochemistry 20121001
Title: Anti-cancer effects of thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP.
Journal: Toxicology letters 20120903
Title: Thymoquinone prevents and ameliorates dextran sulfate sodium-induced colitis in mice.
Journal: Digestive diseases and sciences 20120901
Title: Attenuation of oxidative stress-induced vascular endothelial dysfunction by thymoquinone.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120901
Title: Distribution of primary and specialized metabolites in Nigella sativa seeds, a spice with vast traditional and historical uses.
Journal: Molecules (Basel, Switzerland) 20120824
Title: Synthesis of double mesoporous core-shell silica spheres with tunable core porosity and their drug release and cancer cell apoptosis properties.
Journal: Journal of colloid and interface science 20120715
Title: Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats.
Journal: Human & experimental toxicology 20120701
Title: Characterization of thymoquinone binding to human α₁-acid glycoprotein.
Journal: Journal of pharmaceutical sciences 20120701
Title: Thymoquinone improves aging-related endothelial dysfunction in the rat mesenteric artery.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120701
Title: Mitigation of obesity-promoted diseases by Nigella sativa and thymoquinone.
Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20120601
Title: Thymoquinone and proanthocyanidin attenuation of diabetic nephropathy in rats.
Journal: European review for medical and pharmacological sciences 20120601
Title: Effect of thymoquinone, a constituent of Nigella sativa L., on ischemia-reperfusion in rat skeletal muscle.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120501
Title: Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501
Title: Cadmium-induced hepatotoxicity and its abrogation by thymoquinone.
Journal: Journal of biochemical and molecular toxicology 20120501
Title: Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats.
Journal: Chemico-biological interactions 20120415
Title: Thymoquinone accelerates new bone formation in the rapid maxillary expansion procedure.
Journal: Archives of oral biology 20120401
Title: Protective effects of thymoquinone against cholestatic oxidative stress and hepatic damage after biliary obstruction in rats.
Journal: Journal of molecular histology 20120401
Title: Volatile compounds of black cumin seeds (Nigella sativa L.) from microwave-heating and conventional roasting.
Journal: Journal of food science 20120401
Title: Selective extraction of oxygenated compounds from oregano with sub-critical water.
Journal: Journal of the science of food and agriculture 20120315
Title: In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol.
Journal: The Southeast Asian journal of tropical medicine and public health 20120301
Title: Thymoquinone: potential cure for inflammatory disorders and cancer.
Journal: Biochemical pharmacology 20120215
Title: [Role of NF-κB in the anti-tumor effect of thymoquinone on bladder cancer].
Journal: Zhonghua yi xue za zhi 20120214
Title: Preventive effects of thymoquinone in a rat periodontitis model: a morphometric and histopathological study.
Journal: Journal of periodontal research 20120201
Title: Thymoquinone ameliorates the immunological and histological changes induced by exposure to imidacloprid insecticide.
Journal: The Journal of toxicological sciences 20120201
Title: Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo.
Journal: Biochemical and biophysical research communications 20120113
Title: Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons.
Journal: BMC neuroscience 20120101
Title: Effect of thymoquinone on cytosolic pH and Na+/H+ exchanger activity in mouse dendritic cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE.
Journal: PloS one 20120101
Title: Thymoquinone, the Nigella sativa bioactive compound, prevents circulatory oxidative stress caused by 1,2-dimethylhydrazine in erythrocyte during colon postinitiation carcinogenesis.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Thymoquinone ameliorates bacterial translocation and inflammatory response in rats with intestinal obstruction.
Journal: International journal of surgery (London, England) 20120101
Title: Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors.
Journal: PloS one 20120101
Title: High-performance liquid chromatography quantification of principal antioxidants in black seed (Nigella sativa L.) phytopharmaceuticals.
Journal: Journal of AOAC International 20120101
Title: Antineoplastic and apoptotic potential of traditional medicines thymoquinone and diosgenin in squamous cell carcinoma.
Journal: PloS one 20120101
Title: Contrasting actions of diesel exhaust particles on the pulmonary and cardiovascular systems and the effects of thymoquinone.
Journal: British journal of pharmacology 20111201
Title: Upregulation of chemoprotective enzymes and glutathione by Nigella sativa (black seed) and thymoquinone in CCl4-intoxicated rats.
Journal: International journal of toxicology 20111201
Title: Comparative evaluation of anti-inflammatory properties of thymoquinone and curcumin using an asthmatic murine model.
Journal: International immunopharmacology 20111201
Title: [Inhibitory effects of thymoquinone on human pancreatic carcinoma orthotopically implanted in nude mice].
Journal: Zhonghua yi xue za zhi 20111129
Title: Thymoquinone-induced platelet apoptosis.
Journal: Journal of cellular biochemistry 20111101
Title: Vascular endothelial growth factor stimulates endothelial colony forming cells proliferation and tubulogenesis by inducing oscillations in intracellular Ca2+ concentration.
Journal: Stem cells (Dayton, Ohio) 20111101
Title: Synergism from combinations of cisplatin and oxaliplatin with quercetin and thymoquinone in human ovarian tumour models.
Journal: Anticancer research 20111101
Title: Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis.
Journal: Cell biology international 20111001
Title: Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111001
Title: Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo.
Journal: The American journal of pathology 20111001
Title: Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.
Journal: Biochemical pharmacology 20110901
Title: Protective effects of thymoquinone against methotrexate-induced testicular injury.
Journal: Human & experimental toxicology 20110801
Title: Effect of thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N-1-acetyl-transferase gene expression induced by renal ischaemia-reperfusion in rats.
Journal: The Journal of pharmacy and pharmacology 20110801
Title: [Anti-metastasis effect of thymoquinone on human pancreatic cancer].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110801
Title: Ameliorative effect of thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice.
Journal: Current eye research 20110701
Title: Synthesis and characterization of PHV-block-mPEG diblock copolymer and its formation of amphiphilic nanoparticles for drug delivery.
Journal: Journal of nanoscience and nanotechnology 20110701
Title: Thymoquinone attenuates lung injury induced by chronic toluene exposure in rats.
Journal: Toxicology and industrial health 20110601
Title: Cellular localisation of antitumoral 6-alkyl thymoquinones revealed by an alkyne-azide click reaction and the streptavidin-biotin system.
Journal: Chembiochem : a European journal of chemical biology 20110516
Title: Stability-indicating ultra-performance liquid chromatography method for the estimation of thymoquinone and its application in biopharmaceutical studies.
Journal: Biomedical chromatography : BMC 20110501
Title: Nigella sativa seed extract and its bioactive compound thymoquinone: the new melanogens causing hyperpigmentation in the wall lizard melanophores.
Journal: The Journal of pharmacy and pharmacology 20110501
Title: Thymoquinone ameliorates chemical induced oxidative stress and β-cell damage in experimental hyperglycemic rats.
Journal: Chemico-biological interactions 20110425
Title: Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma.
Journal: Free radical biology & medicine 20110415
Title: Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin.
Journal: Cancer chemotherapy and pharmacology 20110401
Title: Monoamine reuptake inhibition and mood-enhancing potential of a specified oregano extract.
Journal: The British journal of nutrition 20110401
Title: Thymoquinone reestablishes spermatogenesis after testicular injury caused by chronic toluene exposure in rats.
Journal: Toxicology and industrial health 20110301
Title: Protective effects of thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure.
Journal: Journal of molecular histology 20110201
Title: The protective effect of thymoquinone against sepsis syndrome morbidity and mortality in mice.
Journal: International immunopharmacology 20110201
Title: Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione.
Journal: Bioorganic & medicinal chemistry 20110201
Title: Determination of oxygen radical absorbance capacity of black cumin (Nigella sativa) seed quinone compounds.
Journal: Natural product communications 20110201
Title: Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells.
Journal: Mutation research 20110110
Title: Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis.
Journal: Journal of cellular biochemistry 20110101
Title: Thymoquinone supplementation attenuates cyclophosphamide-induced cardiotoxicity in rats.
Journal: Journal of biochemical and molecular toxicology 20110101
Title: The effect of thymoquinone on intractable pediatric seizures (pilot study).
Journal: Epilepsy research 20110101
Title: Perinatal supplementation with thymoquinone improves diabetic complications and T cell immune responses in rat offspring.
Journal: Cellular immunology 20110101
Title: Validated high-performance thin-layer chromatographic method for the quantification of thymoquinone in Nigella Sativa extracts and formulations.
Journal: Phytochemical analysis : PCA 20110101
Title: Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation.
Journal: BMC complementary and alternative medicine 20110101
Title: Antibacterial and resistance-modifying activities of thymoquinone against oral pathogens.
Journal: Annals of clinical microbiology and antimicrobials 20110101
Title: Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels.
Journal: Pharmacological reports : PR 20110101
Title: Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Journal: PloS one 20110101
Title: Thymoquinone, the active ingredient of Nigella sativa seeds, enhances survival and activity of antigen-specific CD8-positive T cells in vitro.
Journal: British journal of biomedical science 20110101
Title: Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression.
Journal: Lipids in health and disease 20110101
Title: The histopathological effect of thymoquinone on experimentally induced rhinosinusitis in rats.
Journal: American journal of rhinology & allergy 20110101
Title: Detection of the antibacterial effect of Nigella sativa ground seeds with water.
Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101
Title: Anticancer activities of Nigella sativa (black cumin).
Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101
Title: Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β-cells of streptozotocin-induced diabetic rats.
Journal: Journal of diabetes 20101201
Title: Thymoquinone inhibits matrix metalloproteinase expression in rabbit chondrocytes and cartilage in experimental osteoarthritis.
Journal: Experimental biology and medicine (Maywood, N.J.) 20101201
Title: Amphiphilic PHA-mPEG copolymeric nanocontainers for drug delivery: preparation, characterization and in vitro evaluation.
Journal: International journal of pharmaceutics 20101115
Title: Structural and vibrational analysis of thymoquinone.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101001
Title: Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway.
Journal: British journal of pharmacology 20101001
Title: Evaluation of chemopreventive effects of Thymoquinone on cell surface glycoconjugates and cytokeratin expression during DMBA induced hamster buccal pouch carcinogenesis.
Journal: BMB reports 20101001
Title: In vitro growth-inhibitory effect of plant-derived extracts and compounds against Paenibacillus larvae and their acute oral toxicity to adult honey bees.
Journal: Veterinary microbiology 20100928
Title: Thymoquinone, a potential therapeutic agent of Nigella sativa, binds to site I of human serum albumin.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100801
Title: Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo.
Journal: Glycoconjugate journal 20100801
Title: Delivery of phytochemical thymoquinone using molecular micelle modified poly(D, L lactide-co-glycolide) (PLGA) nanoparticles.
Journal: Nanotechnology 20100716
Title: Attenuation of high cholesterol-induced oxidative stress in rabbit liver by thymoquinone.
Journal: European journal of gastroenterology & hepatology 20100701
Title: Tumor-selective amphiphilic para-quinones and tetramic acids.
Journal: International journal of clinical pharmacology and therapeutics 20100701
Title: Thymoquinone enhances the activities of enzymes related to energy metabolism in peripheral leukocytes of diabetic rats.
Journal: Research in veterinary science 20100601
Title: Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential.
Journal: Biochemical pharmacology 20100601
Title: Structure-activity studies on therapeutic potential of Thymoquinone analogs in pancreatic cancer.
Journal: Pharmaceutical research 20100601
Title: Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species.
Journal: Experimental biology and medicine (Maywood, N.J.) 20100601
Title: Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1.
Journal: Biochemical pharmacology 20100501
Title: Protective effect of Nigella sativa extract and thymoquinone on serum/glucose deprivation-induced PC12 cells death.
Journal: Cellular and molecular neurobiology 20100501
Title: Effects of thymoquinone on isolated and cellular proteasomes.
Journal: The FEBS journal 20100501
Title: Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies.
Journal: Molecular cancer therapeutics 20100501
Title: Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9.
Journal: Glycoconjugate journal 20100401
Title: Thymoquinone supplementation ameliorates acute endotoxemia-induced liver dysfunction in rats.
Journal: Pakistan journal of pharmaceutical sciences 20100401
Title: Protective effects of propolis and thymoquinone on development of atherosclerosis in cholesterol-fed rabbits.
Journal: Archives of pharmacal research 20100401
Title: Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats.
Journal: Free radical biology & medicine 20100301
Title: Thymoquinone-induced relaxation of isolated rat pulmonary artery.
Journal: Journal of ethnopharmacology 20100203
Title: The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs.
Journal: Planta medica 20100201
Title: Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
Journal: Apoptosis : an international journal on programmed cell death 20100201
Title: Terpene conjugates of the Nigella sativa seed-oil constituent thymoquinone with enhanced efficacy in cancer cells.
Journal: Chemistry & biodiversity 20100101
Title: Effect of thymoquinone on mouse dendritic cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide.
Journal: British journal of biomedical science 20100101
Title: Thymoquinone supplementation reverses acetaminophen-induced oxidative stress, nitric oxide production and energy decline in mice liver.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Title: Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Protective effect of thymoquinone in experimental testicular torsion.
Journal: Urologia internationalis 20100101
Title: Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells.
Journal: PloS one 20100101
Title: Review on molecular and therapeutic potential of thymoquinone in cancer.
Journal: Nutrition and cancer 20100101
Title: Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling.
Journal: Oxidative medicine and cellular longevity 20100101
Title: Effect of thymoquinone on the lung pathology and cytokine levels of ovalbumin-sensitized guinea pigs.
Journal: Pharmacological reports : PR 20100101
Title: Quantitative determination of chemical constituents from seeds of Nigella sativa L. using HPLC-UV and identification by LC-ESI-TOF.
Journal: Journal of AOAC International 20100101
Title: Beneficial effects of thymoquinone on hepatic key enzymes in streptozotocin-nicotinamide induced diabetic rats.
Journal: Life sciences 20091216
Title: [Analysis on chemical components of volatile oil and determination of thymoquinone from seed of Nigella glandulifera].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101
Title: Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and toxicity.
Journal: Phytotherapy research : PTR 20090901
Title: The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20090901
Title: Thymoquinone-induced suicidal erythrocyte death.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090701
Title: Antitumor activity of gemcitabine and oxaliplatin is augmented by thymoquinone in pancreatic cancer.
Journal: Cancer research 20090701
Title: Thymoquinone protects dopaminergic neurons against MPP+ and rotenone.
Journal: Phytotherapy research : PTR 20090501
Title: Effects of thymoquinone-fatty acid conjugates on cancer cells.
Journal: ChemMedChem 20090501
Title: HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090401
Title: HIV-1 protease inhibitor induced oxidative stress in pancreatic beta-cells: protection with thymoquinone.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090401
Title: Therapeutic effects of Nigella sativa on chronic HAART-induced hyperinsulinemia in rats.
Journal: Canadian journal of physiology and pharmacology 20090401
Title: Protective effects of thymoquinone on streptozotocin-induced diabetic nephropathy.
Journal: Journal of molecular histology 20090401
Title: Thymoquinone inhibits germination of dermatophyte arthrospores.
Journal: Saudi medical journal 20090301
Title: Composition of essential oil compounds from different Syrian populations of Origanum syriacum L. (Lamiaceae).
Journal: Journal of agricultural and food chemistry 20090225
Title: In vitro toxicological properties of thymoquinone.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
Title: Anti-cancer properties of Nigella spp. essential oils and their major constituents, thymoquinone and beta-elemene.
Journal: Current clinical pharmacology 20090101
Title: Enrichment of the thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction.
Journal: Journal of separation science 20090101
Title: Effects of Nigella sativa oil and thymoquinone on oxidative stress and neuropathy in streptozotocin-induced diabetic rats.
Journal: Pharmacology 20090101
Title: Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells.
Journal: Journal of nutrigenetics and nutrigenomics 20090101
Title: Antioxidant activities of the supercritical and conventional Satureja montana extracts.
Journal: Journal of food science 20090101
Title: Calculation of LD50 values from the method of Miller and Tainter, 1944.
Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20090101
Title: Role of Nigella sativa and a number of its antioxidant constituents towards azoxymethane-induced genotoxic effects and colon cancer in rats.
Journal: Phytotherapy research : PTR 20081001
Title: Thymoquinone ameliorates renal oxidative damage and proliferative response induced by mercuric chloride in rats.
Journal: Basic & clinical pharmacology & toxicology 20080801
Title: Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells.
Journal: Cancer research 20080715
Title: Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways.
Journal: Molecular cancer therapeutics 20080701
Title: Activity of 1,4-benzoquinones against formosan subterranean termites (Coptotermes formosanus).
Journal: Journal of agricultural and food chemistry 20080611
Title: Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
Journal: Molecular cancer research : MCR 20080601
Title: Reduction of hypervalent states of myoglobin and hemoglobin to their ferrous forms by thymoquinone: the role of GSH, NADH and NADPH.
Journal: Biochimica et biophysica acta 20080401
Title: Thymoquinone protects renal tubular cells against tubular injury.
Journal: Cell biochemistry and function 20080401
Title: Nigella sativa and derived thymoquinone prevents hippocampal neurodegeneration after chronic toluene exposure in rats.
Journal: Neurochemical research 20080301
Title: n-Hexane toxicity in Jurkat T-cells is mediated by reactive oxygen species.
Journal: Archives of toxicology 20080301
Title: The effect of nigellone and thymoquinone on inhibiting trachea contraction and mucociliary clearance.
Journal: Planta medica 20080201
Title: Effects of Nigella sativa and its major constituent, thymoquinone on sciatic nerves in experimental diabetic neuropathy.
Journal: Neurochemical research 20080101
Title: Effects of borneol and thymoquinone on TNBS-induced colitis in mice.
Journal: Folia biologica 20080101
Title: Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models.
Journal: Journal of cellular and molecular medicine 20080101
Title: Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats.
Journal: Urology journal 20080101
Title: Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats.
Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20080101
Title: Effect of thymoquinone on malformations and oxidative stress-induced diabetic mice.
Journal: Pakistan journal of biological sciences : PJBS 20070915
Title: Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20070901
Title: Effects of thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models.
Journal: Phytotherapy research : PTR 20070901
Title: Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells.
Journal: Phytotherapy research : PTR 20070901
Title: Androgen receptor and E2F-1 targeted thymoquinone therapy for hormone-refractory prostate cancer.
Journal: Cancer research 20070815
Title: Thymoquinone suppressses in vitro production of IL-5 and IL-13 by mast cells in response to lipopolysaccharide stimulation.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070801
Title: Inhibitory effects of topical thymoquinone on corneal neovascularization.
Journal: Cornea 20070701
Title: Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats.
Journal: Phytotherapy research : PTR 20070501
Title: Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation.
Journal: Biochimica et biophysica acta 20070401
Title: In vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives thymoquinone and thymohydroquinone.
Journal: Phytotherapy research : PTR 20070301
Title: Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.
Journal: Cancer biology & therapy 20070201
Title: Nonenzymatic reduction of thymoquinone in physiological conditions.
Journal: Free radical research 20070201
Title: Anticlastogenic activity of thymoquinone against benzo(a)pyrene in mice.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070101
Title: Thymoquinone supplementation prevents the development of gentamicin-induced acute renal toxicity in rats.
Journal: Clinical and experimental pharmacology & physiology 20070101
Title: LNCaP cells exposed to ceramic drug delivery treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid.
Journal: Biomedical sciences instrumentation 20070101
Title: A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
Journal: Biomedical sciences instrumentation 20070101
Title: Physiological responses of ES-2 ovarian cell line following administration of epigallocatechin-3-gallate (EGCG), thymoquinone (TQ), and selenium (SE).
Journal: Biomedical sciences instrumentation 20070101
Title: Protective effects of thymoquinone and methotrexate on the renal injury in collagen-induced arthritis.
Journal: Archives of toxicology 20061101
Title: Effects of thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models.
Journal: Phytotherapy research : PTR 20061001
Title: The antitumor activity of thymoquinone and thymohydroquinone in vitro and in vivo.
Journal: Experimental oncology 20060901
Title: Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus.
Journal: European journal of pharmacology 20060814
Title: Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation.
Journal: Immunology letters 20060715
Title: Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma.
Journal: Biochimica et biophysica acta 20060701
Title: Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation.
Journal: International immunopharmacology 20060701
Title: The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, thymoquinone on ethanol-induced gastric mucosal damage.
Journal: Archives of toxicology 20060401
Title: Evaluation of the effect of terpenoid quinones on Trichophyton mentagrophytes by solution and vapor contact.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060401
Title: Thymoquinone: a promising anti-cancer drug from natural sources.
Journal: The international journal of biochemistry & cell biology 20060101
Title: Effects of thymoquinone, lycopene, and selenomethione in the presence of estrogen on the viability of SiHa cells in vitro.
Journal: Biomedical sciences instrumentation 20060101
Title: The effect of conventional and sustained delivery of thymoquinone and levodopa on SH-SY5Y human neuroblastoma cells.
Journal: Biomedical sciences instrumentation 20060101
Title: The role of glucosamine, chondroitin and thymoquinone on the viability and proliferation of a HTB-93 rheumatoid arthritis cell model.
Journal: Biomedical sciences instrumentation 20060101
Title: Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.
Journal: Biomedical sciences instrumentation 20060101
Title: The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line.
Journal: Biomedical sciences instrumentation 20060101
Title: Effects of (-)epigallocatechin gallate and thymoquinone on proliferation of a PANC-1 cell line in culture.
Journal: Biomedical sciences instrumentation 20060101
Title: Thymoquinone reduces hepatic glucose production in diabetic hamsters.
Journal: Research in veterinary science 20051201
Title: Immunomodulatory and therapeutic properties of the Nigella sativa L. seed.
Journal: International immunopharmacology 20051201
Title: Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats.
Journal: World journal of gastroenterology 20051114
Title: Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells.
Journal: International journal of cancer 20051110
Title: Antidermatophyte activity of ether extract of Nigella sativa and its active principle, thymoquinone.
Journal: Journal of ethnopharmacology 20051003
Title: A new agent for treatment of acute respiratory distress syndrome: thymoquinone. An experimental study in a rat model.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050801
Title: Serotonin glucuronidation by Ah receptor- and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells.
Journal: Biochemical pharmacology 20050501
Title: Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20050401
Title: Effect of solution conductivity on the volatile constituents of Origanum dictamnus L. in nutrient film culture.
Journal: Journal of agricultural and food chemistry 20050309
Title: Macrophage-derived cytokine and nitric oxide profiles in type I and type II diabetes mellitus: effect of thymoquinone.
Journal: Acta diabetologica 20050301
Title: Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism.
Journal: International immunopharmacology 20050101
Title: Comparison of the amelioration effects of two enzyme inducers on the inflammatory process of experimental allergic encephalitis (EAE) using immunohistochemical technique.
Journal: Biomedical sciences instrumentation 20050101
Title: Thymoquinone inhibits the activation of NF-kappaB in the brain and spinal cord of experimental autoimmune encephalomyelitis.
Journal: Biomedical sciences instrumentation 20050101
Title: Effects of alpha-hederin and thymoquinone, constituents of Nigella sativa, on human cancer cell lines.
Journal: Anticancer research 20050101
Title: Modes of action of alpha-hederin and thymoquinone, active constituents of Nigella sativa, against HEp-2 cancer cells.
Journal: Anticancer research 20050101
Title: Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.
Journal: International journal of oncology 20041001
Title: Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone.
Journal: Journal of enzyme inhibition and medicinal chemistry 20041001
Title: Crystal structure determination of thymoquinone by high-resolution X-ray powder diffraction.
Journal: AAPS PharmSciTech 20040601
Title: Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes.
Journal: Anti-cancer drugs 20040401
Title: Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats.
Journal: International journal of cardiology 20040101
Title: Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds, in mice.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101
Title: Effects of sustained delivery of thymoqiunone on bone healing of male rats.
Journal: Biomedical sciences instrumentation 20040101
Title: Thymoquinone protects against experimental colitis in rats.
Journal: Toxicology letters 20030720
Title: Thymoquinone is a potent superoxide anion scavenger.
Journal: Drug and chemical toxicology 20030501
Title: Pharmacological and toxicological properties of Nigella sativa.
Journal: Phytotherapy research : PTR 20030401
Title: Gastroprotective activity of Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats.
Journal: Journal of ethnopharmacology 20030201
Title: In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone.
Journal: International journal of oncology 20030101
Title: Improvement of experimental allergic encephalomyelitis (EAE) by thymoquinone; an oxidative stress inhibitor.
Journal: Biomedical sciences instrumentation 20030101
Title: A simple differential pulse polarographic method for the determination of thymoquinone in black seed oil.
Journal: Phytochemical analysis : PCA 20030101
Title: Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages.
Journal: International immunopharmacology 20021001
Title: Nigella sativa oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats.
Journal: Journal of ethnopharmacology 20020701
Title: Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action.
Journal: Cell biochemistry and function 20020601
Title: The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions.
Journal: Planta medica 20020501
Title: Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping.
Journal: Mutation research 20020426
Title: The effect of thymoquinone on blood lipids in rats.
Journal: Indian journal of physiology and pharmacology 20020401
Title: Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis.
Journal: Cancer detection and prevention 20010101
Title: Effects of volatile oil constituents of Nigella sativa on carbon tetrachloride-induced hepatotoxicity in mice: evidence for antioxidant effects of thymoquinone.
Journal: Research communications in molecular pathology and pharmacology 20010101
Title: Thymoquinone-induced relaxation of guinea-pig isolated trachea.
Journal: Research communications in molecular pathology and pharmacology 20010101
Title: The influence of thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats.
Journal: Toxicology 20000307
Title: Thymoquinone attenuates ifosfamide-induced Fanconi syndrome in rats and enhances its antitumor activity in mice.
Journal: Journal of ethnopharmacology 19991101
Title: Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity.
Journal: Journal of experimental & clinical cancer research : CR 19980601
Title: Khader M, et al. Thymoquinone: an emerging natural drug with a wide range of medical applications. Iran J Basic Med Sci. 2014 Dec;17(12):950-7.
