Title: Synthesis and comparison of antiplasmodial activity of (+), (-) and racemic 7-chloro-4-(N-lupinyl)aminoquinoline.
Journal: Bioorganic & medicinal chemistry 20121001
Title: Asymmetric synthesis of trans-2,3-disubstituted indoline derivatives.
Journal: The Journal of organic chemistry 20120106
Title: [Derivatives of lupinin and epilupinin as ligands of various cholinesterases].
Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20120101
Title: [Isomeric derivatives of lupinine and epilupinine--organophosphorus inhibitors of cholinesterases].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20120101
Title: [Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal].
Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20120101
Title: Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.
Journal: The Journal of organic chemistry 20110805
Title: Total syntheses of (-) epilupinine and (-)-tashiromine using imino-aldol reactions.
Journal: Organic letters 20110805
Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal: Journal of medicinal chemistry 20110714
Title: Synthesis of the azaphilones (+)-sclerotiorin and (+)-8-O-methylsclerotiorinamine utilizing (+)-sparteine surrogates in copper-mediated oxidative dearomatization.
Journal: The Journal of organic chemistry 20110415
Title: Total synthesis of (+)-epilupinine via an intramolecular nitrile oxide-alkene cycloaddition.
Journal: The Journal of organic chemistry 20110107
Title: Development and application of a method to investigate drug-metabolizing enzyme inhibitors using sparteine for probe of cytochrome P450 2D6 and tris(2,2'-bipyridine)ruthenium(II)-electrogenerated chemiluminescence detection.
Journal: Chemical & pharmaceutical bulletin 20110101
Title: Experimental and computational study of a direct O2-coupled Wacker oxidation: water dependence in the absence of Cu salts.
Journal: Journal of the American Chemical Society 20100901
Title: Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?
Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100701
Title: Characterization of a rhodium-sparteine complex, [((-)-sparteine)Rh(eta4-COD)]+: crystal structure and DNMR/DFT studies on ligand-rotation dynamics.
Journal: Dalton transactions (Cambridge, England : 2003) 20100321
Title: Short access to (+)-lupinine and (+)-epiquinamide via double hydroformylation.
Journal: Organic letters 20100205
Title: Asymmetric catalysis of homo-coupling of 3-substituted naphthylamine and hetero-coupling with 3-substituted naphthol leading to 3,3'-dimethyl-2,2'-diaminobinaphthyl and -2-amino-2'-hydroxybinaphthyl.
Journal: Chirality 20100201
Title: Estimation of the interindividual variability of cytochrome 2D6 activity from urinary metabolic ratios in the literature.
Journal: Drug metabolism and pharmacokinetics 20100101
Title: Reactions of (-)-sparteine with alkali metal HMDS complexes: conventional meets the unconventional.
Journal: Chemical communications (Cambridge, England) 20091021
Title: Optically active (aR)- and (aS)-linear and vaulted biaryl ligands: deracemization versus oxidative dimerization.
Journal: Journal of the American Chemical Society 20091014
Title: Enantiomerization dynamics and a catalytic dynamic resolution of N-trimethylallyl-2-lithiopyrrolidine.
Journal: Journal of the American Chemical Society 20090527
Title: Epiquinamide: a poison that wasn't from a frog that was.
Journal: Journal of natural products 20090227
Title: Total synthesis of (+/-)-alpha-isosparteine, (+/-)-beta-isosparteine, and (+/-)-sparteine from a common tetraoxobispidine intermediate.
Journal: The Journal of organic chemistry 20081017
Title: A new catalytic Cu(II)/sparteine oxidant system for beta,beta-phenolic couplings of styrenyl phenols: synthesis of carpanone and unnatural analogs.
Journal: Organic letters 20080918
Title: A direct stereoselective approach to trans-2,3-disubstituted piperidines: application in the synthesis of 2-Epi-CP-99,994 and (+)-epilupinine.
Journal: Organic letters 20080619
Title: A new sparteine surrogate for asymmetric deprotonation of N-Boc pyrrolidine.
Journal: Organic letters 20080403
Title: Basic instinct: design, synthesis and evaluation of (+)-sparteine surrogates for asymmetric synthesis.
Journal: Chemical communications (Cambridge, England) 20080214
Title: Asymmetric lithiation-substitution of amines involving rearrangement of borates.
Journal: Organic letters 20080103
Title: Cholinesterase hydrolysis of substituted lupinine benzoates.
Journal: Doklady. Biochemistry and biophysics 20080101
Title: Bactericidal and fungicidal activities of Calia secundiflora (Ort.) Yakovlev.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101
Title: Stereocontrolled synthesis and alkylation of cyclic beta-amino esters: asymmetric synthesis of a (-)-sparteine surrogate.
Journal: Organic & biomolecular chemistry 20071121
Title: A (-)-sparteine-directed highly enantioselective synthesis of boroproline. Solid- and solution-state structure and properties.
Journal: The Journal of organic chemistry 20070803
Title: A natural variant of the heme-binding signature (R441C) resulting in complete loss of function of CYP2D6.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801
Title: Hypoglycaemic effect of quinolizidine alkaloids--lupanine and 2-thionosparteine on non-diabetic and streptozotocin-induced diabetic rats.
Journal: European journal of pharmacology 20070622
Title: [Phenotypes of oxidation and acetylation in Alzheimer's disease--preliminary report].
Journal: Psychiatria polska 20070101
Title: Enantioselective nitroaldol (Henry) reaction using copper(II) complexes of (-)-sparteine.
Journal: Chemical communications (Cambridge, England) 20061021
Title: Neuronal damage and changes in the expression of muscarinic acetylcholine receptor subtypes in the neonatal rat cerebral cortical upon exposure to sparteine, a quinolizidine alkaloid.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20061001
Title: Pd(II)-catalyzed conversion of styrene derivatives to acetals: impact of (-)-sparteine on regioselectivity.
Journal: Organic letters 20060316
Title: Pd(II)-catalyzed enantioselective oxidative tandem cyclization reactions. Synthesis of indolines through C-N and C-C bond formation.
Journal: Journal of the American Chemical Society 20060315
Title: Asymmetric synthesis of 4,5,6- and 3,4,5,6-substituted azepanes by a highly diastereoselective and enantioselective lithiation-conjugate addition sequence.
Journal: Journal of the American Chemical Society 20060222
Title: [Clinical significance of oxidation and acetylation genetic polymorphism in patients with hyperthyreosis].
Journal: Endokrynologia Polska 20060101
Title: Origin of enantioselection in chiral alcohol oxidation catalyzed by Pd[(-)-sparteine]Cl2.
Journal: Journal of the American Chemical Society 20051026
Title: A practical synthesis of (+/-)-alpha-isosparteine from a tetraoxobispidine core.
Journal: Organic letters 20051013
Title: Stereocontrolled total synthesis of (-)-kainic acid. Regio- and stereoselective lithiation of pyrrolidine ring with the (+)-sparteine surrogate.
Journal: Organic letters 20050929
Title: Enantioselective lithiation of O-alkyl and O-alk-2-enyl Carbamates in the presence of (-)-sparteine and (-)-alpha-isosparteine. A theoretical study.
Journal: The Journal of organic chemistry 20050527
Title: Cascade iminium ion reactions for the facile synthesis of quinolizidines. Concise syntheses of (+/-)-epilupinine and (-)-epimyrtine.
Journal: Organic letters 20050512
Title: A synthesis of (+/-)-sparteine.
Journal: Organic & biomolecular chemistry 20050421
Title: Absolute configuration of 2-(tributylstannyl)pyrrolidine by anomalous dispersion X-ray analysis.
Journal: The Journal of organic chemistry 20050107
Title: [Synthesis of lupinine derivatives of flavonoids].
Journal: Bioorganicheskaia khimiia 20050101
Title: Is the A-ring of sparteine essential for high enantioselectivity in the asymmetric lithiation-substitution of N-Boc-pyrrolidine?
Journal: Journal of the American Chemical Society 20041201
Title: An experimental and computational study of the enantioselective lithiation of N-Boc-pyrrolidine using sparteine-like chiral diamines.
Journal: Journal of the American Chemical Society 20041201
Title: Comparison of plasma disposition of alkaloids after lupine challenge in cattle that had given birth to calves with lupine-induced arthrogryposis or clinically normal calves.
Journal: American journal of veterinary research 20041101
Title: Total synthesis of (-)-alpha-kainic acid by (-)-sparteine-mediated asymmetric deprotonation-cycloalkylation.
Journal: Organic letters 20041014
Title: Effect of ligand structure on the asymmetric cyclization of achiral olefinic organolithiums.
Journal: The Journal of organic chemistry 20040903
Title: Synthesis of a new N-acetyl thiazolidinethione reagent and its application to a highly selective asymmetric acetate aldol reaction.
Journal: Organic letters 20040902
Title: Concise asymmetric synthesis of (-)-sparteine.
Journal: Chemical communications (Cambridge, England) 20040821
Title: Evaluation of (+)-sparteine-like diamines for asymmetric synthesis.
Journal: The Journal of organic chemistry 20040820
Title: A short synthesis of (+/-)-cytisine.
Journal: Organic & biomolecular chemistry 20040707
Title: Double ring-closing metathesis reaction of nitrogen-containing tetraenes: efficient construction of bicyclic alkaloid skeletons and synthetic application to four stereoisomers of lupinine and their derivatives.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040705
Title: A computational model relating structure and reactivity in enantioselective oxidations of secondary alcohols by (-)-sparteine-Pd(II) complexes.
Journal: Journal of the American Chemical Society 20040630
Title: [Application of bisalkaloid derivatives of dicarboxylic acids based on lupinine, anabasine and cytisine as cholinesterase inhibitors of various origin].
Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20040101
Title: Palladium-catalyzed aerobic oxidative kinetic resolution of alcohols with an achiral exogenous base.
Journal: The Journal of organic chemistry 20030919
Title: Mechanistic investigations of the palladium-catalyzed aerobic oxidative kinetic resolution of secondary alcohols using (-)-sparteine.
Journal: Journal of the American Chemical Society 20030611
Title: Scope of enantioselective palladium(II)-catalyzed aerobic alcohol oxidations with (-)-sparteine.
Journal: The Journal of organic chemistry 20030530
Title: Synthetic applications of lithiated N-Boc allylic amines as asymmetric homoenolate equivalents.
Journal: The Journal of organic chemistry 20030221
Title: Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.
Journal: Journal of medicinal chemistry 20030102
Title: Bisalkaloid derivatives of dicarboxylic acids on the basis of lupinine, anabasine, and cytisine as reversible cholinesterase inhibitors.
Journal: Doklady. Biochemistry and biophysics 20030101
Title: A readily-accessible (+)-sparteine surrogate.
Journal: Journal of the American Chemical Society 20021009
Title: Enantioselective synthesis of 2-substituted 2-phenylethylamines by lithiation-substitution sequences: synthetic development and mechanistic pathway.
Journal: The Journal of organic chemistry 20020920
Title: Control of the conformational equilibria in aza-cis-decalins: structural modification, solvation, and metal chelation.
Journal: The Journal of organic chemistry 20020906
Title: First asymmetric total synthesis of (+)-sparteine.
Journal: Organic letters 20020725
Title: Practical and highly selective oxazolidinethione-based asymmetric acetate aldol reactions with aliphatic aldehydes.
Journal: Organic letters 20020627
Title: Thesinine-4'-O-beta-D-glucoside the first glycosylated plant pyrrolizidine alkaloid from Borago officinalis.
Journal: Phytochemistry 20020601
Title: Lobocyclamide B from Lyngbya confervoides. Configuration and asymmetric synthesis of beta-hydroxy-alpha-amino acids by (-)-sparteine-mediated aldol addition.
Journal: Organic letters 20020530
Title: Conformational control of flexible molecules: design and synthesis of novel chiral 1,5-diaza-cis-decalins.
Journal: The Journal of organic chemistry 20020503
Title: Bacterial removal of quinolizidine alkaloids and other carbon sources from a Lupinus albus aqueous extract.
Journal: Journal of agricultural and food chemistry 20020410
Title: Acute hypoxia and cytochrome P450-mediated hepatic drug metabolism in humans.
Journal: Clinical pharmacology and therapeutics 20020401
Title: An experimental and computational investigation of the enantioselective deprotonation of Boc-piperidine.
Journal: Journal of the American Chemical Society 20020306
Title: Effect of growth hormone on hepatic cytochrome P450 activity in healthy elderly men.
Journal: Clinical pharmacology and therapeutics 20020301
Title: Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers.
Journal: British journal of clinical pharmacology 20011201
Title: Dose-dependent inhibition of the CYP2D6 catalyzed oxidation of sparteine by mepyramine in healthy volunteers.
Journal: Pharmacology & toxicology 20011201
Title: Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test.
Journal: Clinical pharmacology and therapeutics 20011001
Title: Indolizidine and quinolizidine alkaloids.
Journal: Natural product reports 20011001
Title: Chiral diamines 4: a computational study of the enantioselective deprotonation of Boc-pyrrolidine with an alkyllithium in the presence of a chiral diamine.
Journal: Journal of the American Chemical Society 20010829
Title: Absorption and disposition of levocetirizine, the eutomer of cetirizine, administered alone or as cetirizine to healthy volunteers.
Journal: Fundamental & clinical pharmacology 20010801
Title: Influence of CYP2D6 genotype and medication on the sparteine metabolic ratio of psychiatric patients.
Journal: European journal of clinical pharmacology 20010701
Title: Kinetics and mechanism of the (-)-sparteine-mediated deprotonation of (E)-N-Boc-N-(p-methoxyphenyl)-3-cyclohexylallylamine.
Journal: Journal of the American Chemical Society 20010530
Title: Novel sparteine-mediated enantio-dichotomic formal synthesis of R-(-)- and S-(+)-curcuphenol.
Journal: The Journal of organic chemistry 20010420
Title: Synthesis of enantiomerically enriched allenes by (-)-sparteine-mediated lithiation of alkynyl carbamates.
Journal: Organic letters 20010419
Title: Moving toward genetic profiling in patient care: the scope and rationale of pharmacogenetic/ecogenetic investigation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010401
Title: 2-(4-R-phenoxy/phenylthio)alkanoic esters of l-lupinine.
Journal: Farmaco (Societa chimica italiana : 1989) 20010301
Title: Asymmetric aldol additions: use of titanium tetrachloride and (-)-sparteine for the soft enolization of N-acyl oxazolidinones, oxazolidinethiones, and thiazolidinethiones.
Journal: The Journal of organic chemistry 20010209
Title: Immunolocalization of alkaloids and X-ray microanalysis of elements in lupin seeds.
Journal: Protoplasma 20010101
Title: Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis.
Journal: Scandinavian journal of gastroenterology 19930801
Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
Journal: Journal of natural products 19910101
Title: Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine.
Journal: Klinische Wochenschrift 19871215
Title: Screening for new compounds with antiherpes activity.
Journal: Antiviral research 19841001
Title: Antifibrillatory, cardiovascular and toxic effects of sparteine, butylsparteine and pentylsparteine.
Journal: Arzneimittel-Forschung 19800101
Title: [Effect of sparteine sulfate on the predamaged conduction system of the heart].
Journal: Zeitschrift fur Kardiologie 19750501
Title: Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5.