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499-04-7,MFCD00985225
Catalog No.:AA006XT3

499-04-7 | Arecaidine But-2-Ynyl Ester Tosylate

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5mg
98.0%
in stock  
$286.00   $200.00
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10mg
98.0%
in stock  
$375.00   $263.00
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25mg
98.0%
in stock  
$774.00   $542.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006XT3
Chemical Name:
Arecaidine But-2-Ynyl Ester Tosylate
CAS Number:
499-04-7
Molecular Formula:
C7H11NO2
Molecular Weight:
141.1677
MDL Number:
MFCD00985225
SMILES:
CN1CC(=CCC1)C(=O)O
NSC Number:
76017
Properties
Computed Properties
 
Complexity:
174  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
-2.3  

Literature

Title: Potential action of betel alkaloids on positive and negative symptoms of schizophrenia: a review.

Journal: Nordic journal of psychiatry 20120401

Title: Alkaloids from areca (betel) nuts and their effects on human sperm motility in vitro.

Journal: Journal of food science 20120401

Title: The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.

Journal: British journal of pharmacology 20111201

Title: High-throughput simultaneous analysis of five urinary metabolites of areca nut and tobacco alkaloids by isotope-dilution liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101001

Title: Quantification of blood betel quid alkaloids and urinary 8-hydroxydeoxyguanosine in humans and their association with betel chewing habits.

Journal: Journal of analytical toxicology 20100101

Title: Urotheliogenic modulation of intrinsic activity in spinal cord-transected rat bladders: role of mucosal muscarinic receptors.

Journal: American journal of physiology. Renal physiology 20080801

Title: Role of hyperglycaemia in the pathogenesis of hypotension observed in type-1 diabetic rats.

Journal: International journal of experimental pathology 20080801

Title: Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system.

Journal: BJU international 20070901

Title: The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases.

Journal: Biochemical pharmacology 20070215

Title: Genetic damage in cultured human keratinocytes stressed by long-term exposure to areca nut extracts.

Journal: Mutation research 20060725

Title: Oral submucous fibrosis: review on aetiology and pathogenesis.

Journal: Oral oncology 20060701

Title: Muscarinic stimulation of the mouse isolated whole bladder: physiological responses in young and ageing mice.

Journal: Autonomic & autacoid pharmacology 20060701

Title: A metabolomic approach to the metabolism of the areca nut alkaloids arecoline and arecaidine in the mouse.

Journal: Chemical research in toxicology 20060601

Title: Bladder volume alters cholinergic responses of the isolated whole mouse bladder.

Journal: The Journal of urology 20060201

Title: Comparison study of autonomous activity in bladders from normal and paraplegic rats.

Journal: Neurourology and urodynamics 20060101

Title: Volume-induced effects on the isolated bladder: a possible local reflex.

Journal: BJU international 20041201

Title: Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.

Journal: The Journal of physiology 20041001

Title: Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron.

Journal: Pain 20040101

Title: Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill.

Journal: BMC neuroscience 20040101

Title: Comparative in vitro permeability of human vaginal, small intestinal and colonic mucosa.

Journal: International journal of pharmaceutics 20030811

Title: Agonist- and nerve-induced phasic activity in the isolated whole bladder of the guinea pig: evidence for two types of bladder activity.

Journal: Experimental physiology 20030501

Title: Autonomous activity in the isolated guinea pig bladder.

Journal: Experimental physiology 20030101

Title: Muscarinic M2 receptors inhibit heat-induced CGRP release from isolated rat skin.

Journal: Neuroreport 20010808

Title: Cancer induction in the DMBA hamster cheek pouch: a modified technique using a promoter.

Journal: The Laryngoscope 20010201

Title: D Lodge, et al. Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain Res. 1977 Nov 18;136(3):513-22.

Title: Valerie Voigt, et al. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). J Pharm Pharmacol. 2013 Apr;65(4):582-90.

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