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4998-57-6,MFCD00005208
Catalog No.:AA006WQH

4998-57-6 | D,L-histidine

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Purity
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10g
95%
in stock  
$12.00   $8.00
- +
25g
95%
in stock  
$27.00   $19.00
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100g
95%
in stock  
$90.00   $63.00
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500g
98%
in stock  
$411.00   $288.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006WQH
Chemical Name:
D,L-histidine
CAS Number:
4998-57-6
Molecular Formula:
C6H9N3O2
Molecular Weight:
155.1546
MDL Number:
MFCD00005208
SMILES:
NC(C(=O)O)Cc1c[nH]cn1
Properties
Properties
 
BP:
458.9°C at 760 mmHg  
Form:
Solid  
MP:
273 °C  
Refractive Index:
1.6500 (estimate)  
Solubility:
0.5 M HCl: soluble  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
151  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-3.2  

Upstream Synthesis Route

[1]Hoppe-Seyler'sZeitschriftfuerPhysiologischeChemie,1912,vol.77,p.437,438

[2]JournalofBiologicalChemistry,1936,vol.115,p.93,97

[1]JournalofBiologicalChemistry,1945,vol.160,p.441,442

[2]JournalofBiologicalChemistry,1936,vol.115,p.93,97

[1]JournaloftheChemicalSociety,1911,vol.99,p.344

[1]BulletinoftheChemicalSocietyofJapan,1991,vol.64,#12,p.3741-3742

[1]JournaloftheChemicalSociety,1916,vol.109,p.197

Downstream Synthesis Route
2-acetylamino-2-cyano-3-(1(3)<i>H</i>-imidazol-4-yl)-propionicacidethylester 
  4998-57-6 

[1]JournaloftheAmericanChemicalSociety,1945,vol.67,p.502

[1]JournaloftheChemicalSociety,1911,vol.99,p.1391

[1]BiochemischeZeitschrift,1914,vol.63,p.388

[2]Hoppe-Seyler'sZeitschriftfurPhysiologischeChemie,1912,vol.77,p.437,438

[1]BiomedicalMassSpectrometry,1979,vol.6,p.381-391

2-Acetylamino-2-(3H-imidazol-4-ylmethyl)-malonicaciddiethylester 
  4998-57-6 

[1]Tetrahedron,1986,vol.42,p.4481-4492

Literature

Title: The first 3':5'-cyclic nucleotide-amino acid complex: L-His-cIMP.

Journal: Acta crystallographica. Section C, Crystal structure communications 20120801

Title: HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children.

Journal: PLoS pathogens 20120301

Title: Complex formation, chemical exchange, species structure, and stereoselective effects in the copper(II)-L/DL-histidine systems.

Journal: Dalton transactions (Cambridge, England : 2003) 20120128

Title: Salmonella transiently reside in luminal neutrophils in the inflamed gut.

Journal: PloS one 20120101

Title: RNA interference is responsible for reduction of transgene expression after Sleeping Beauty transposase mediated somatic integration.

Journal: PloS one 20120101

Title: Chemiluminescence of the reaction system Ce(IV)-non-steroidal anti-inflammatory drugs containing europium(III) ions and its application to the determination of naproxen in pharmaceutical preparations and urine.

Journal: Journal of fluorescence 20111101

Title: [Study on the enhancement diphacinone-europium fluorescence system and application for determination of the residue in urine].

Journal: Wei sheng yan jiu = Journal of hygiene research 20110701

Title: EphrinB/EphB signaling controls embryonic germ layer separation by contact-induced cell detachment.

Journal: PLoS biology 20110301

Title: Expression of recombinant Araraquara Hantavirus nucleoprotein in insect cells and its use as an antigen for immunodetection compared to the same antigen expressed in Escherichia coli.

Journal: Virology journal 20110101

Title: Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.

Journal: International journal of molecular sciences 20110101

Title: Primary and secondary thyroid hormone transporters.

Journal: Thyroid research 20110101

Title: The influence of bovine milk high or low in isoflavones on hepatic gene expression in mice.

Journal: Journal of toxicology 20100101

Title: Elevated cell-specific microparticles are a biological marker for cerebral dysfunctions in human severe malaria.

Journal: PloS one 20100101

Title: CTCF regulates the local epigenetic state of ribosomal DNA repeats.

Journal: Epigenetics & chromatin 20100101

Title: Mutation of the histidin residue of the DRH motif in vasopressin V2 receptor expression and function.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101

Title: Amino acid ionic liquids as chiral ligands in ligand-exchange chiral separations.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090928

Title: MCRS2 represses the transactivation activities of Nrf1.

Journal: BMC cell biology 20090101

Title: RNase 7 contributes to the cutaneous defense against Enterococcus faecium.

Journal: PloS one 20090101

Title: Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions.

Journal: BMC genomics 20070101

Title: Antiglucocorticoid RU38486 reduces net protein catabolism in experimental acute renal failure.

Journal: BMC nephrology 20050101

Title: Characterization of an immunologic polymorphism (D79H) in the heavy chain of factor V.

Journal: Journal of thrombosis and haemostasis : JTH 20040601

Title: Comparative analysis of somitogenesis related genes of the hairy/Enhancer of split class in Fugu and zebrafish.

Journal: BMC genomics 20020101

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