Home Carboxes 500025-07-0
500025-07-0,MFCD05130922
Catalog No.:AA00DFU8

500025-07-0 | 3-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]propanoic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$83.00   $58.00
- +
250mg
95%
in stock  
$144.00   $101.00
- +
500mg
95%
in stock  
$203.00   $142.00
- +
1g
95%
in stock  
$285.00   $200.00
- +
2g
95%
in stock  
$538.00   $377.00
- +
5g
95%
in stock  
$886.00   $621.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DFU8
Chemical Name:
3-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]propanoic acid
CAS Number:
500025-07-0
Molecular Formula:
C11H9FN2O3
Molecular Weight:
236.1992
MDL Number:
MFCD05130922
SMILES:
OC(=O)CCc1onc(n1)c1ccc(cc1)F
Properties
Computed Properties
 
Complexity:
269  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
1.7  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartCheng,Yuan;Albrecht,BrianK.;Brown,James;Buchanan,JohnL.;Buckner,WilliamH.;DiMauro,ErinF.;Emkey,Renee;FremeauJr.,RobertT.;Harmange,Jean-Christophe;Hoffman,BethJ.;Huang,Liyue;Huang,Ming;Lee,JosieHan;Lin,Fen-Fen;Martin,MatthewW.;Nguyen,HungQ.;Patel,VinodF.;Tomlinson,SusanA.;White,RyanD.;Xia,Xiaoyang;Hitchcock,StephenA.[JournalofMedicinalChemistry,2008,vol.51,#16,p.5019-5034]

[2]Barbosa,AndreydaS.;Barbosa,AndreydaS.;Maciel,LarissaG.;Soares,TherezaA.;deAlencar-Filho,EdilsonB.;dosAnjos,JanaínaV.

[1]Locationinpatent:experimentalpartCheng,Yuan;Albrecht,BrianK.;Brown,James;Buchanan,JohnL.;Buckner,WilliamH.;DiMauro,ErinF.;Emkey,Renee;FremeauJr.,RobertT.;Harmange,Jean-Christophe;Hoffman,BethJ.;Huang,Liyue;Huang,Ming;Lee,JosieHan;Lin,Fen-Fen;Martin,MatthewW.;Nguyen,HungQ.;Patel,VinodF.;Tomlinson,SusanA.;White,RyanD.;Xia,Xiaoyang;Hitchcock,StephenA.[JournalofMedicinalChemistry,2008,vol.51,#16,p.5019-5034]

[1]Locationinpatent:experimentalpartNevesFilho,RicardoAntonioWanderley;DaSilva,CeciliaAguiar;DaSilva,CleciaSiprianoBorges;Brustein,VanessaPassos;Navarro,DanielaMariaDoAmaralFerraz;DosSantos,FabioAndreBrayner;Alves,LuizCarlos;Cavalcanti,MariliaGabrielaDosSantos;Srivastava,RajendraMohan;Carneiro-Da-Cunha,MariaDasGracas[ChemicalandPharmaceuticalBulletin,2009,vol.57,#8,p.819-825]

[1]Lueg,Corinna;Schepmann,Dirk;Günther,Robert;Brust,Peter;Wünsch,Bernhard[BioorganicandMedicinalChemistry,2013,vol.21,#23,p.7481-7498]

500025-07-0   
2-(3-amino-9H-carbazol-9-yl)ethan-1-olhydrochloride 
 
3-3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl-N-9-(2-hydroxyethyl)-9H-carbazol-3-ylpropanamide 

[1]Lueg,Corinna;Schepmann,Dirk;Günther,Robert;Brust,Peter;Wünsch,Bernhard[BioorganicandMedicinalChemistry,2013,vol.21,#23,p.7481-7498]

Literature

Title: Improved microwave-mediated synthesis of 3-(3-aryl-1,2,4-oxadiazol-5-yl)propionic acids and their larvicidal and fungal growth inhibitory properties.

Journal: Chemical & pharmaceutical bulletin 20090801

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:500025-07-0 Molecular Formula|500025-07-0 MDL|500025-07-0 SMILES|500025-07-0 3-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]propanoic acid