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500715-03-7
Catalog No.:AA01V3UZ

500715-03-7 | IK1 inhibitor PA-6

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
95%
1 week  
$96.00   $68.00
- +
5mg
95%
1 week  
$119.00   $84.00
- +
10mg
95%
1 week  
$178.00   $124.00
- +
25mg
95%
1 week  
$284.00   $199.00
- +
50mg
95%
1 week  
$442.00   $309.00
- +
100mg
95%
1 week  
$621.00   $435.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA01V3UZ
Chemical Name:
IK1 inhibitor PA-6
CAS Number:
500715-03-7
Molecular Formula:
C31H32N4O2
Molecular Weight:
492.6114
SMILES:
N=C(c1ccccc1)Nc1ccc(cc1)OCCCCCOc1ccc(cc1)NC(=N)c1ccccc1
Properties

Literature

Title: Takanari H, et al. Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue. Cardiovasc Res. 2013 Jul 1;99(1):203-14.

Title: Ji Y, et al. The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. Br J Pharmacol. 2017 Aug;174(15):2576-2590.

Title: Ji Y, et al. PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression. J Biomed Sci. 2017 Jul 15;24(1):44.

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SDS
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