Catalog No.:AA01V6P8

501364-82-5 | INO-1001

Name: Name:INO-1001
Brand: AABLOCKS
SKU: AA01V6P8
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

5mg

98%

1 week

$204.00 $143.00

- +

10mg

98%

1 week

$320.00 $224.00

- +

100mg

98%

1 week

$525.00 $368.00

- +

250mg

98%

1 week

$787.00 $551.00

- +

Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA01V6P8

Chemical Name:

INO-1001

CAS Number:

501364-82-5

Molecular Formula:

C23H25N3O4S

Molecular Weight:

439.5273

MDL Number:

MFCD19443171

SMILES:

O=c1[nH]c2c3ccc(cc3Cc2c2c1cccc2)S(=O)(=O)NCCCN1CCOCC1

Properties

Downstream Synthesis Route

501364-67-6

123-00-2

501364-82-5

[1]Jagtap,PrakashG.;Baloglu,Erkan;Southan,GarryJ.;Mabley,JonG.;Li,Hongshan;Zhou,Jing;VanDuzer,John;Salzman,AndrewL.;Szabó,Csaba[JournalofMedicinalChemistry,2005,vol.48,#16,p.5100-5103]

[2]CurrentPatentAssignee:ROCKETPHARMACEUTICALSINC-WO2005/82368,2005,A1Locationinpatent:Page/Pagecolumn60;86-87

[3]CurrentPatentAssignee:ROCKETPHARMACEUTICALSINC-US2006/19980,2006,A1Locationinpatent:Page/Pagecolumn31-33;54

[4]CurrentPatentAssignee:ROCKETPHARMACEUTICALSINC-US2006/19980,2006,A1Locationinpatent:Page/Pagecolumn31-33;54

501364-82-5

74-88-4

4-methyl-4-3-(5-oxo-5,11-dihydro-6<i>H</i>-indeno1,2-<i>c</i>isoquinoline-9-sulfonylamino)-propyl-morpholin-4-ium;iodide

[1]Jagtap,PrakashG.;Baloglu,Erkan;Southan,GarryJ.;Mabley,JonG.;Li,Hongshan;Zhou,Jing;VanDuzer,John;Salzman,AndrewL.;Szabó,Csaba[JournalofMedicinalChemistry,2005,vol.48,#16,p.5100-5103]

109722-74-9

501364-82-5

[1]Jagtap,PrakashG.;Baloglu,Erkan;Southan,GarryJ.;Mabley,JonG.;Li,Hongshan;Zhou,Jing;VanDuzer,John;Salzman,AndrewL.;Szabó,Csaba[JournalofMedicinalChemistry,2005,vol.48,#16,p.5100-5103]

5264-21-1

501364-82-5

[1]Jagtap,PrakashG.;Baloglu,Erkan;Southan,GarryJ.;Mabley,JonG.;Li,Hongshan;Zhou,Jing;VanDuzer,John;Salzman,AndrewL.;Szabó,Csaba[JournalofMedicinalChemistry,2005,vol.48,#16,p.5100-5103]

[2]Jagtap,PrakashG.;Baloglu,Erkan;Southan,GarryJ.;Mabley,JonG.;Li,Hongshan;Zhou,Jing;VanDuzer,John;Salzman,AndrewL.;Szabó,Csaba[JournalofMedicinalChemistry,2005,vol.48,#16,p.5100-5103]

5291-20-3

501364-82-5

[1]Jagtap,PrakashG.;Baloglu,Erkan;Southan,GarryJ.;Mabley,JonG.;Li,Hongshan;Zhou,Jing;VanDuzer,John;Salzman,AndrewL.;Szabó,Csaba[JournalofMedicinalChemistry,2005,vol.48,#16,p.5100-5103]

Literature

Title: Brock WA, et al. Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase. Cancer Lett. 2004 Mar 18;205(2):155-60.

Title: Mason KA, et al. INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase, enhances tumor response to doxorubicin. Invest New Drugs. 2008 Feb;26(1):1-5. Epub 2007 Jul 13.

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