[1]Rami,HarshadK.;Thompson,Mervyn;Stemp,Geoffrey;Fell,Steve;Jerman,JeffreyC.;Stevens,AlexanderJ.;Smart,Darren;Sargent,Becky;Sanderson,Dominic;Randall,AndrewD.;Gunthorpe,MartinJ.;Davis,JohnB.[BioorganicandMedicinalChemistryLetters,2006,vol.16,#12,p.3287-3291]
[1]Rami,HarshadK.;Thompson,Mervyn;Stemp,Geoffrey;Fell,Steve;Jerman,JeffreyC.;Stevens,AlexanderJ.;Smart,Darren;Sargent,Becky;Sanderson,Dominic;Randall,AndrewD.;Gunthorpe,MartinJ.;Davis,JohnB.[BioorganicandMedicinalChemistryLetters,2006,vol.16,#12,p.3287-3291]
[1]Rami,HarshadK.;Thompson,Mervyn;Stemp,Geoffrey;Fell,Steve;Jerman,JeffreyC.;Stevens,AlexanderJ.;Smart,Darren;Sargent,Becky;Sanderson,Dominic;Randall,AndrewD.;Gunthorpe,MartinJ.;Davis,JohnB.[BioorganicandMedicinalChemistryLetters,2006,vol.16,#12,p.3287-3291]
Title: Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig.
Journal: British journal of pharmacology 20120701
Title: Effect of mucosal TRPV1 inhibition in allergic rhinitis.
Journal: Basic & clinical pharmacology & toxicology 20120301
Title: TRPV1 antagonists: clinical setbacks and prospects for future development.
Journal: Progress in medicinal chemistry 20120101
Title: Effect of transient receptor potential vanilloid 1 (TRPV1) receptor antagonist compounds SB705498, BCTC and AMG9810 in rat models of thermal hyperalgesia measured with an increasing-temperature water bath.
Journal: European journal of pharmacology 20100901
Title: Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
Journal: Journal of medicinal chemistry 20100422
Title: Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091001
Title: The effects of the TRPV1 receptor antagonist SB-705498 on trigeminovascular sensitisation and neurotransmission.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20091001
Title: Analgesic potential of TRPV1 antagonists.
Journal: Biochemical pharmacology 20090801
Title: Capsaicin receptor antagonists: a promising new addition to the pain clinic.
Journal: British journal of anaesthesia 20090201
Title: TRPing the switch on pain: an introduction to the chemistry and biology of capsaicin and TRPV1.
Journal: Chemical Society reviews 20080801
Title: The effects of the TRPV1 antagonist SB-705498 on TRPV1 receptor-mediated activity and inflammatory hyperalgesia in humans.
Journal: Pain 20071101
Title: Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20070601
Title: Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development.
Journal: Bioorganic & medicinal chemistry letters 20060615
Title: Martin J. Gunthorpe, et al. Characterization of SB-705498, a Potent and Selective Vanilloid Receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor. JPET June 2007 vol. 321 no. 3 1183-1192.
Title: Rami HK, et al. Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3287-91.
