50357-46-5,MFCD01667817
Catalog No.:AA00DDBY

50357-46-5 | Hexamidine Dihydrochloride

This product is typically in stock,please click "Inquire" below or
contact us at [email protected] for pricing and availability information.
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DDBY
Chemical Name:
Hexamidine Dihydrochloride
CAS Number:
50357-46-5
Molecular Formula:
C20H26N4O2
Molecular Weight:
354.4460
MDL Number:
MFCD01667817
SMILES:
NC(=N)c1ccc(cc1)OCCCCCCOc1ccc(cc1)C(=N)N
Properties
Computed Properties
 
Complexity:
388  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
11  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: A double-blind randomized controlled comparison of APDDR-0901, a novel cosmeceutical formulation, and 0.1% adapalene gel in the treatment of mild-to-moderate acne vulgaris.

Journal: European journal of dermatology : EJD 20110101

Title: Antiseptic properties of two calix[4]arenes derivatives on the human coronavirus 229E.

Journal: Antiviral research 20101201

Title: Action potential-enhanced ATP release from taste cells through hemichannels.

Journal: Journal of neurophysiology 20100801

Title: Cationic compounds with activity against multidrug-resistant bacteria: interest of a new compound compared with two older antiseptics, hexamidine and chlorhexidine.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100501

Title: [Infectious keratitis and cosmetic lenses: a five-case retrospective study].

Journal: Journal francais d'ophtalmologie 20100401

Title: p-Guanidinoethyl calixarene and parent phenol derivatives exhibiting antibacterial activities. Synthesis and biological evaluation.

Journal: Bioorganic & medicinal chemistry 20090801

Title: Structure-activity study of pentamidine analogues as antiprotozoal agents.

Journal: Journal of medicinal chemistry 20090409

Title: Rapidly progressive cataract and iris atrophy during treatment of Acanthamoeba keratitis.

Journal: Ophthalmology 20080501

Title: Bilateral acanthamoeba keratitis.

Journal: American journal of ophthalmology 20080201

Title: Visual outcome and rehabilitation in a case of bilateral acanthamoeba sclerokeratitis.

Journal: Cornea 20071001

Title: Antistaphylococcal activities of CG400549, a new bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor.

Journal: The Journal of antimicrobial chemotherapy 20070901

Title: In vitro activity of para-guanidinoethylcalix[4]arene against susceptible and antibiotic-resistant Gram-negative and Gram-positive bacteria.

Journal: The Journal of antimicrobial chemotherapy 20070901

Title: [Acanthamoeba keratitis: about the first two Tunisian cases].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20070201

Title: Final report on the safety assessment of Hexamidine and Hexamidine Diisethionate.

Journal: International journal of toxicology 20070101

Title: Systemic allergy to topical hexamidine.

Journal: The Medical journal of Australia 20060807

Title: A keratitis rat model for evaluation of anti-Acanthamoeba polyphaga agents.

Journal: Cornea 20060601

Title: Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage.

Journal: Cornea 20060401

Title: [Towards new antibacterial drugs. Interest of para-guanidinoethylcalix[4]arene].

Journal: Pathologie-biologie 20060101

Title: Acanthamoeba keratitis during orthokeratology.

Journal: Cornea 20051001

Title: Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.

Journal: The Journal of biological chemistry 20040402

Title: Persistently culture positive acanthamoeba keratitis: in vivo resistance and in vitro sensitivity.

Journal: Ophthalmology 20030801

Title: Bilateral Acanthamoeba keratitis with late recurrence of the infection in a corneal graft: a case report.

Journal: European journal of ophthalmology 20030401

Title: [Treatment of Acanthamoeba keratitis: possibilities, problems, and new approaches].

Journal: Wiener klinische Wochenschrift 20030101

Title: Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia.

Journal: Journal of medicinal chemistry 19900401

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SDS
Tags:50357-46-5 Molecular Formula|50357-46-5 MDL|50357-46-5 SMILES|50357-46-5 Hexamidine Dihydrochloride
Catalog No.: AA00DDBY
50357-46-5,MFCD01667817
50357-46-5 | Hexamidine Dihydrochloride
This product is typically in stock,please click "Inquire" below or contact us at [email protected]for pricing and availability information.
Inquire
Technical Information
Catalog Number: AA00DDBY
Chemical Name: Hexamidine Dihydrochloride
CAS Number: 50357-46-5
Molecular Formula: C20H26N4O2
Molecular Weight: 354.4460
MDL Number: MFCD01667817
SMILES: NC(=N)c1ccc(cc1)OCCCCCCOc1ccc(cc1)C(=N)N
Properties
Complexity: 388  
Covalently-Bonded Unit Count: 3  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 11  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: A double-blind randomized controlled comparison of APDDR-0901, a novel cosmeceutical formulation, and 0.1% adapalene gel in the treatment of mild-to-moderate acne vulgaris.

Journal: European journal of dermatology : EJD20110101

Title: Antiseptic properties of two calix[4]arenes derivatives on the human coronavirus 229E.

Journal: Antiviral research20101201

Title: Action potential-enhanced ATP release from taste cells through hemichannels.

Journal: Journal of neurophysiology20100801

Title: Cationic compounds with activity against multidrug-resistant bacteria: interest of a new compound compared with two older antiseptics, hexamidine and chlorhexidine.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases20100501

Title: [Infectious keratitis and cosmetic lenses: a five-case retrospective study].

Journal: Journal francais d'ophtalmologie20100401

Title: p-Guanidinoethyl calixarene and parent phenol derivatives exhibiting antibacterial activities. Synthesis and biological evaluation.

Journal: Bioorganic & medicinal chemistry20090801

Title: Structure-activity study of pentamidine analogues as antiprotozoal agents.

Journal: Journal of medicinal chemistry20090409

Title: Rapidly progressive cataract and iris atrophy during treatment of Acanthamoeba keratitis.

Journal: Ophthalmology20080501

Title: Bilateral acanthamoeba keratitis.

Journal: American journal of ophthalmology20080201

Title: Visual outcome and rehabilitation in a case of bilateral acanthamoeba sclerokeratitis.

Journal: Cornea20071001

Title: Antistaphylococcal activities of CG400549, a new bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor.

Journal: The Journal of antimicrobial chemotherapy20070901

Title: In vitro activity of para-guanidinoethylcalix[4]arene against susceptible and antibiotic-resistant Gram-negative and Gram-positive bacteria.

Journal: The Journal of antimicrobial chemotherapy20070901

Title: [Acanthamoeba keratitis: about the first two Tunisian cases].

Journal: Bulletin de la Societe de pathologie exotique (1990)20070201

Title: Final report on the safety assessment of Hexamidine and Hexamidine Diisethionate.

Journal: International journal of toxicology20070101

Title: Systemic allergy to topical hexamidine.

Journal: The Medical journal of Australia20060807

Title: A keratitis rat model for evaluation of anti-Acanthamoeba polyphaga agents.

Journal: Cornea20060601

Title: Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage.

Journal: Cornea20060401

Title: [Towards new antibacterial drugs. Interest of para-guanidinoethylcalix[4]arene].

Journal: Pathologie-biologie20060101

Title: Acanthamoeba keratitis during orthokeratology.

Journal: Cornea20051001

Title: Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.

Journal: The Journal of biological chemistry20040402

Title: Persistently culture positive acanthamoeba keratitis: in vivo resistance and in vitro sensitivity.

Journal: Ophthalmology20030801

Title: Bilateral Acanthamoeba keratitis with late recurrence of the infection in a corneal graft: a case report.

Journal: European journal of ophthalmology20030401

Title: [Treatment of Acanthamoeba keratitis: possibilities, problems, and new approaches].

Journal: Wiener klinische Wochenschrift20030101

Title: Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia.

Journal: Journal of medicinal chemistry19900401

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