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504-20-1,MFCD00008901
Catalog No.:AA0035ZJ

504-20-1 | 2,6-Dimethyl-2,5-heptadien-4-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$6.00   $4.00
- +
5g
98%
in stock  
$17.00   $12.00
- +
10g
95%
in stock  
$29.00   $20.00
- +
25g
98%
in stock  
$68.00   $48.00
- +
100g
98%
in stock  
$195.00   $137.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0035ZJ
Chemical Name:
2,6-Dimethyl-2,5-heptadien-4-one
CAS Number:
504-20-1
Molecular Formula:
C9H14O
Molecular Weight:
138.2069
MDL Number:
MFCD00008901
SMILES:
O=C(C=C(C)C)C=C(C)C
UN Number:
1993
Properties
Properties
 
BP:
198-199°C at 760 mmHg  
Form:
Liquid  
MP:
28°C  
Refractive Index:
n20/D 1.497(lit.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
157  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.8  

Literature

Title: Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170201

Title: Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5.

Journal: Redox biology 20140101

Title: Phorone A and isophorbasone A, sesterterpenoids isolated from the marine sponge Phorbas sp.

Journal: Organic letters 20120907

Title: Calcium antagonists modulate oxidative stress and acrosomal reaction in rat spermatozoa.

Journal: Archives of medical science : AMS 20110801

Title: Mechanism-based biomarker gene sets for glutathione depletion-related hepatotoxicity in rats.

Journal: Toxicology and applied pharmacology 20100915

Title: Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-kappaB.

Journal: Biochemical pharmacology 20100801

Title: c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.

Journal: Toxicology and applied pharmacology 20100701

Title: Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090301

Title: Toxicogenomic biomarkers for liver toxicity.

Journal: Journal of toxicologic pathology 20090301

Title: The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts.

Journal: PloS one 20090101

Title: Red Cabbage (Brassica oleracea) Ameliorates Diabetic Nephropathy in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20080901

Title: Comparison of the effects of buthioninesulfoximine and phorone on the metabolism of sulfur-containing amino acids in rat liver.

Journal: Biochemical and biophysical research communications 20080418

Title: Identification of glutathione depletion-responsive genes using phorone-treated rat liver.

Journal: The Journal of toxicological sciences 20071201

Title: Decolorization potential of mixed microbial consortia for reactive and disperse textile dyestuffs.

Journal: Biodegradation 20070601

Title: High hepatic glutathione stores alleviate Fas-induced apoptosis in mice.

Journal: Journal of hepatology 20070501

Title: Serum iron increases with acute induction of hepatic heme oxygenase-1 in mice.

Journal: Drug metabolism reviews 20070101

Title: Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue.

Journal: Journal of clinical biochemistry and nutrition 20070101

Title: Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice.

Journal: Journal of hepatology 20060701

Title: Phosphorinanes as ligands for palladium-catalyzed cross-coupling chemistry.

Journal: Organic letters 20060105

Title: The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress.

Journal: Free radical biology & medicine 20050401

Title: Glycogenolysis is directed towards ascorbate synthesis by glutathione conjugation.

Journal: Biochemical and biophysical research communications 20040423

Title: Synthesis of radioiodine labeled dibenzyl disulfide for evaluation of tumor cell uptake.

Journal: Bioorganic & medicinal chemistry 20040301

Title: Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031101

Title: Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress.

Journal: American journal of physiology. Cell physiology 20030801

Title: Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20020701

Title: Role of glutathione in metabolic degradation of dichloromethane in rats.

Journal: Toxicology letters 20020324

Title: Activation of transcription factors by drugs inducing oxidative stress in rat liver.

Journal: Biochemical pharmacology 20020115

Title: Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice.

Journal: Hepatology (Baltimore, Md.) 20010501

Title: Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.

Journal: Pharmacology & toxicology 20010401

Title: CD95-Mediated murine hepatic apoptosis requires an intact glutathione status.

Journal: Hepatology (Baltimore, Md.) 19990701

Title: Differential activation of heat-shock and oxidation-specific stress genes in chemically induced oxidative stress.

Journal: The Biochemical journal 19950715

Title: Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers.

Journal: Chemico-biological interactions 19950330

Title: Phorone (diisopropylidene acetone), a glutathione depletor, decreases rat glucocorticoid receptor binding in vivo.

Journal: Carcinogenesis 19920701

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