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504-31-4,MFCD00006639
Catalog No.:AA003NPS

504-31-4 | Alpha-pyrone

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100mg
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$29.00   $20.00
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250mg
97%
in stock  
$52.00   $36.00
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1g
>98.0%(GC)
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NPS
Chemical Name:
Alpha-pyrone
CAS Number:
504-31-4
Molecular Formula:
C5H4O2
Molecular Weight:
96.0841
MDL Number:
MFCD00006639
SMILES:
O=c1cccco1
Properties
Properties
 
BP:
207.5°C at 760 mmHg  
Form:
Liquid  
MP:
8-9 °C  
Refractive Index:
n20/D 1.53(lit.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
133  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
0.8  

Literature

Title: Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death.

Journal: Toxicology letters 20130912

Title: Anti-leukemic effect of 2-pyrone derivatives via MAPK and PI3 kinase pathways.

Journal: Investigational new drugs 20121201

Title: Changes in Maillard reaction products in ghee during storage.

Journal: Food chemistry 20121201

Title: Inhibition of Acyl-CoA: cholesterol acyltransferase (ACAT), overexpression of cholesterol transporter gene, and protection of amyloid β (Aβ) oligomers-induced neuronal cell death by tricyclic pyrone molecules.

Journal: Journal of medicinal chemistry 20121025

Title: Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway.

Journal: Chembiochem : a European journal of chemical biology 20121015

Title: Structure based molecular design, synthesis and biological evaluation of α-pyrone analogs as anti-HSV agent.

Journal: Bioorganic & medicinal chemistry letters 20121001

Title: Transport of the anti-diabetic VO2+ complexes formed by pyrone derivatives in the blood serum.

Journal: Journal of inorganic biochemistry 20121001

Title: Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action.

Journal: Bioorganic & medicinal chemistry 20120915

Title: A new 2-pyrone derivative, 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one, suppresses stemness in glioma stem-like cells.

Journal: Molecular pharmacology 20120901

Title: Total synthesis and structural elucidation of ent-micropyrone and (+)-ascosalipyrone.

Journal: Organic & biomolecular chemistry 20120828

Title: Assembly of an evolutionarily new pathway for α-pyrone biosynthesis in Arabidopsis.

Journal: Science (New York, N.Y.) 20120824

Title: In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-γ-pyrone skeleton.

Journal: European journal of medicinal chemistry 20120801

Title: 6-Hy-droxy-7,8-dimethyl-chroman-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120801

Title: In vitro antitrypanosomal activity of some phenolic compounds from propolis and lactones from Fijian Kawa (Piper methysticum).

Journal: Journal of natural medicines 20120701

Title: Thieno[3,2-c]pyran-4-one based novel small molecules: their synthesis, crystal structure analysis and in vitro evaluation as potential anticancer agents.

Journal: Bioorganic & medicinal chemistry letters 20120701

Title: 5,6-Dimethyl-1,2,9,10-tetra-hydro-pyrano[3,2-f]chromene-3,8-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20120701

Title: The cephalostatins. 22. synthesis of bis-steroidal pyrazine pyrones (1).

Journal: Journal of natural products 20120622

Title: Positive diversifying selection on Plasmodium vivax RON2 protein.

Journal: Parasitology 20120501

Title: Photipyrones A and B, new pyrone derivatives from the plant endophytic fungus Pestalotiopsis photiniae.

Journal: The Journal of antibiotics 20120501

Title: 3-Benzyl-2H-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Depsidones, aromatase inhibitors and radical scavenging agents from the marine-derived fungus Aspergillus unguis CRI282-03.

Journal: Planta medica 20120401

Title: Regioselective cleavage of 22-oxo-23-spiroketals. Novel cholestanic frameworks with pyranone and cyclopentenone E rings on the side chain.

Journal: Steroids 20120401

Title: 3,3'-Dihy-droxy-6,6'-bis-(hy-droxy-meth-yl)-2,2'-(pentane-1,1-di-yl)di-4H-pyran-4-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: 5,6-Dimethyl-4-phenyl-2H-pyran-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: 3,4-Dimethyl-pyrano[2,3-c]pyrazol-6(2H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii.

Journal: Marine drugs 20120401

Title: (E)-6-Methyl-3-(2-methyl-benzyl-idene)-chroman-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: 3,3'-[(4-Nitro-phen-yl)methyl-ene]bis-(4-hy-droxy-2H-chromen-2-one).

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Toward the synthesis of (+)-peloruside A via an intramolecular vinylogous aldol reaction.

Journal: Organic letters 20120106

Title: A new 2-pyrone derivative, 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one, synergistically enhances radiation sensitivity in human cervical cancer cells.

Journal: Anti-cancer drugs 20120101

Title: 5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: 1'-Methyl-4'-(4-methyl-phen-yl)dispiro-[1-benzopyran-3(4H),3'-pyrrolidine-2',3''-indoline]-2,2''-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: Ethyl 2-(2-amino-5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7-yl)acetate.

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: 4',5-Dihy-droxy-7-meth-oxy-flavanone dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ.

Journal: PloS one 20120101

Title: Seven naphtho-γ-pyrones from the marine-derived fungus Alternaria alternata: structure elucidation and biological properties.

Journal: Organic and medicinal chemistry letters 20120101

Title: Metabolic and proteomic profiling of diapause in the aphid parasitoid Praon volucre.

Journal: PloS one 20120101

Title: The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide.

Journal: PloS one 20120101

Title: Two new flavanols from Glycosmis pentaphylla.

Journal: Journal of Asian natural products research 20120101

Title: Enzymatic properties and mutational studies of chalcone synthase from Physcomitrella patens.

Journal: International journal of molecular sciences 20120101

Title: A selective intramolecular 5-exo-dig or 6-endo-dig cyclization en route to 2-furanone or 2-pyrone containing tricyclic scaffolds.

Journal: The Journal of organic chemistry 20111202

Title: catena-Poly[[[(pyridine-κN)copper(II)]-μ-3-{1-[(2-amino-eth-yl)imino]-eth-yl}-6-methyl-2-oxo-2H-pyran-4-olato-κN,N,O:O] perchlorate].

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: 1',6-Dimethyl-4'-phenyl-dispiro-[1-benzopyran-3(4H),3'-pyrrolidine-2',3''-indoline]-2,2''-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: DFT-based molecular modeling, NBO analysis and vibrational spectroscopic study of 3-(bromoacetyl)coumarin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

Title: Molecular cloning, modeling, and site-directed mutagenesis of type III polyketide synthase from Sargassum binderi (Phaeophyta).

Journal: Marine biotechnology (New York, N.Y.) 20111001

Title: Generation of diverse 2-pyrones via palladium-catalyzed site-selective Suzuki-Miyaura couplings of 3-bromo-4-tosyloxy-2-pyrone.

Journal: Organic & biomolecular chemistry 20110921

Title: 3-(9H-Carbazol-9-yl)-2H-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110901

Title: Nigerapyrones A-H, α-pyrone derivatives from the marine mangrove-derived endophytic fungus Aspergillus niger MA-132.

Journal: Journal of natural products 20110826

Title: Asymmetric fluoroallylboration of aldehydes.

Journal: Organic letters 20110805

Title: A new salicylic acid-derivatized kojic acid vanadyl complex: synthesis, characterization and anti-diabetic therapeutic potential.

Journal: Journal of inorganic biochemistry 20110801

Title: Antitumor actinopyranones produced by Streptomyces albus POR-04-15-053 isolated from a marine sediment.

Journal: Journal of natural products 20110722

Title: 6-Hy-droxy-5,7,8-trimethyl-chroman-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Enantiocontrolled total syntheses of breviones A, B, and C.

Journal: Journal of the American Chemical Society 20110615

Title: Syntheses of α-pyrones using gold-catalyzed coupling reactions.

Journal: Organic letters 20110603

Title: Modiolide and pyrone derivatives from the sea fan-derived fungus Curvularia sp. PSU-F22.

Journal: Archives of pharmacal research 20110501

Title: Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity.

Journal: Bioorganic & medicinal chemistry letters 20110415

Title: 8-Iodo-5,7-dimeth-oxy-4-methyl-2H-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110401

Title: Development of easy made low cost bindless monolithic electrodes from biomass with controlled properties to be used as electrochemical capacitors.

Journal: Bioresource technology 20110201

Title: 4-Hy-droxy-3-[(4-hy-droxy-6-methyl-2-oxo-3,6-dihydro-2H-pyran-3-yl)(3-thien-yl)meth-yl]-6-methyl-3,6-dihydro-2H-pyran-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus.

Journal: Neurobiology of aging 20110101

Title: Challenges in identifying sites climatically matched to the native ranges of animal invaders.

Journal: PloS one 20110101

Title: Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum.

Journal: Genome biology 20110101

Title: Biofunctional activity of tortillas and bars enhanced with nopal. Preliminary assessment of functional effect after intake on the oxidative status in healthy volunteers.

Journal: Chemistry Central journal 20110101

Title: PvRON2, a new Plasmodium vivax rhoptry neck antigen.

Journal: Malaria journal 20110101

Title: (3E,5E)-3,5-Bis(4-hy-droxy-benzyl-idene)oxan-4-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: 7,7'-Dihy-droxy-4,4'-dimethyl-3,4-dihydro-2H,2'H-4,6'-bichromene-2,2'-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Phylogenetic identification of fungi isolated from the marine sponge Tethya aurantium and identification of their secondary metabolites.

Journal: Marine drugs 20110101

Title: Diversity and antibacterial activities of fungi derived from the Gorgonian Echinogorgia rebekka from the South China Sea.

Journal: Marine drugs 20110101

Title: Comprehensive network analysis of anther-expressed genes in rice by the combination of 33 laser microdissection and 143 spatiotemporal microarrays.

Journal: PloS one 20110101

Title: Spectroscopic study of solvent effects on the electronic absorption spectra of flavone and 7-hydroxyflavone in neat and binary solvent mixtures.

Journal: International journal of molecular sciences 20110101

Title: Evolutionary development of the plant and spore wall.

Journal: AoB PLANTS 20110101

Title: 3,5-disubstituted pyranone analogues of highly antifungally active furanones: conversion of biological effect from antifungal to cytostatic.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Vibrational and ab initio studies of 3-acetyl-6-bromocoumarin and 3-acetyl-6-methylcoumarin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101201

Title: LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana.

Journal: The Plant cell 20101201

Title: Analysis of TETRAKETIDE α-PYRONE REDUCTASE function in Arabidopsis thaliana reveals a previously unknown, but conserved, biochemical pathway in sporopollenin monomer biosynthesis.

Journal: The Plant cell 20101201

Title: (3E,5E)-3,5-Bis(4-hy-droxy-3,5-di-methoxy-benzyl-idene)oxan-4-one monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Comment on 'Single-crystal X-ray structure of 1,3-dimethylcyclobutadiene by confinement in a crystalline matrix'.

Journal: Science (New York, N.Y.) 20101119

Title: Complex formation between Ru(η(6)-p-cym)(H2O)3]2+ and (O,O) donor ligands with biological relevance in aqueous solution.

Journal: Dalton transactions (Cambridge, England : 2003) 20101114

Title: 3-(Pyridin-2-yl)coumarin.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 4-Bromo-methyl-6-meth-oxy-2H-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Ethyl 3-oxo-3H-benzo[f]chromene-2-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Biochemical changes during goiter induction by methylmercaptoimidazol and inhibition by delta-iodolactone in rat.

Journal: Thyroid : official journal of the American Thyroid Association 20100901

Title: Mycenaaurin A, an antibacterial polyene pigment from the fruiting bodies of Mycena aurantiomarginata.

Journal: Journal of natural products 20100827

Title: Oxovitisins: a new class of neutral pyranone-anthocyanin derivatives in red wines.

Journal: Journal of agricultural and food chemistry 20100811

Title: Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues.

Journal: Journal of the American Chemical Society 20100804

Title: 6 Iodo-delta-lactone reproduces many but not all the effects of iodide.

Journal: Molecular and cellular endocrinology 20100729

Title: Antiproliferative/cytotoxic activity of molecular iodine and iodolactones in various human carcinoma cell lines. No interfering with EGF-signaling, but evidence for apoptosis.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20100701

Title: LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.

Journal: Plant physiology 20100701

Title: Surugapyrone A from Streptomyces coelicoflavus strain USF-6280 as a new DPPH radical-scavenger.

Journal: The Journal of antibiotics 20100701

Title: Formal synthesis of (-)-neopeltolide featuring a highly stereoselective oxocarbenium formation/reduction sequence.

Journal: The Journal of organic chemistry 20100618

Title: Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB.

Journal: Bioorganic & medicinal chemistry 20100615

Title: Phomenins and fatty acids from Alternaria infectoria.

Journal: Toxicon : official journal of the International Society on Toxinology 20100601

Title: Isolation and structure determination of one new metabolite isolated from the red fermented rice of Monascus purpureus.

Journal: Natural product research 20100601

Title: Ethyl (4aR*,7S*,8S*,8aS*)-1-oxo-7-phenyl-3,4,4a,7,8,8a-hexa-hydro-1H-isochromene-8-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: 4-Oxo-2-phenylchroman-6-yl propionate.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors.

Journal: Bioorganic & medicinal chemistry 20100515

Title: Allantopyrone A, a new alpha-pyrone metabolite with potent cytotoxicity from an endophytic fungus, Allantophomopsis lycopodina KS-97.

Journal: The Journal of antibiotics 20100501

Title: Fully and partially fluorinated flavone derivatives.

Journal: Acta crystallographica. Section C, Crystal structure communications 20100501

Title: Formation of a cyclopropyl epoxide via a leukotriene A synthase-related pathway in an anaerobic reaction of soybean lipoxygenase-1 with 15S-hydroperoxyeicosatetraenoic acid: evidence that oxygen access is a determinant of secondary reactions with fatty acid hydroperoxides.

Journal: The Journal of biological chemistry 20100430

Title: Sequential identification of organic dyes using the voltammetry of microparticles approach.

Journal: Talanta 20100415

Title: Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis.

Journal: Journal of the American Chemical Society 20100407

Title: A C14-polyacetylenic glucoside with an alpha-pyrone moiety and four C10-polyacetylenic glucosides from Mediasia macrophylla.

Journal: Phytochemistry 20100401

Title: 6,8-Diiodo-5,7-dimeth-oxy-4-methyl-coumarin.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Modified phenazines from an Indonesian Streptomyces sp.

Journal: Journal of natural products 20100326

Title: Catalytic asymmetric formation of delta-lactones from unsaturated acyl halides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100222

Title: Isolation and structural characterization of two new metabolites from monascus.

Journal: Journal of agricultural and food chemistry 20100210

Title: Advances in quantum and molecular mechanical (QM/MM) simulations for organic and enzymatic reactions.

Journal: Accounts of chemical research 20100119

Title: Novel neofusapyrones isolated from Verticillium dahliae as potent antifungal substances.

Journal: Bioorganic & medicinal chemistry letters 20100115

Title: Rhenium- and manganese-catalyzed synthesis of aromatic compounds from 1,3-dicarbonyl compounds and alkynes.

Journal: The Journal of organic chemistry 20100115

Title: Antioxidant activities of coumarins from Korean medicinal plants and their structure-activity relationships.

Journal: Phytotherapy research : PTR 20100101

Title: Structural and spectroscopic studies on 2-pyranones.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100101

Title: The role of iodine and delta-iodolactone in growth and apoptosis of malignant thyroid epithelial cells and breast cancer cells.

Journal: Hormones (Athens, Greece) 20100101

Title: Novel anti-infective compounds from marine bacteria.

Journal: Marine drugs 20100101

Title: Quasi-drugs developed in Japan for the prevention or treatment of hyperpigmentary disorders.

Journal: International journal of molecular sciences 20100101

Title: Verrucisidinol and verrucosidinol acetate, two pyrone-type polyketides isolated from a marine derived fungus, Penicillium aurantiogriseum.

Journal: Marine drugs 20100101

Title: 4-(4-Chloro-phen-yl)-7,7-dimethyl-7,8-dihydro-4H-1-benzopyran-2,5(3H,6H)-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: An [11]cytochalasin derivative from the marine-derived fungus Xylaria sp. PSU-F100.

Journal: Chemical & pharmaceutical bulletin 20091201

Title: 3-(2-Amino-1,3-thia-zol-4-yl)-6-chloro-2H-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20091116

Title: Electrocyclization of cis-dienals in organic synthesis: a new and versatile synthetic method for the preparation of aryl- and heteroaryl-fused coumarins.

Journal: Chemical communications (Cambridge, England) 20091007

Title: Inhibitory effect of triterpenoid saponins from the leaves of Ilex kudingcha on aggregated LDL-induced lipid deposition in macrophages.

Journal: Planta medica 20091001

Title: Synthesis of sominone and its derivatives based on an RCM strategy: discovery of a novel anti-Alzheimer's disease medicine candidate 'denosomin'.

Journal: Organic letters 20090903

Title: In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents.

Journal: Organic letters 20090903

Title: Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa.

Journal: Journal of experimental botany 20090901

Title: Synthesis of pentopyranosyl-containing thiodisaccharides. Inhibitory activity against beta-glycosidases.

Journal: Bioorganic & medicinal chemistry 20090901

Title: Predicted roles of the uncharacterized clustered genes in aflatoxin biosynthesis.

Journal: Toxins 20090901

Title: Synthesis of functionalized alpha-pyrone and butenolide derivatives by rhodium-catalyzed oxidative coupling of substituted acrylic acids with alkynes and alkenes.

Journal: The Journal of organic chemistry 20090821

Title: De novo asymmetric synthesis of an alpha-6-deoxyaltropyranoside as well as its 2-/3-deoxy and 2,3-dideoxy congeners.

Journal: The Journal of organic chemistry 20090821

Title: Solvation shell structure of cyclooctylpyranone in water solvent and its comparative structure, dynamics and dipole moment in HIV protease.

Journal: Physical chemistry chemical physics : PCCP 20090814

Title: Measurements of the rotational spectra of phenol and 2-pyrone and computational studies of the H-bonded phenol-pyrone dimer.

Journal: The journal of physical chemistry. A 20090813

Title: The use of heterogeneous chemistry for the characterization of functional groups at the gas/particle interface of soot and TiO2 nanoparticles.

Journal: Physical chemistry chemical physics : PCCP 20090807

Title: Gombapyrones, new alpha-pyrone metabolites produced by Streptomyces griseoruber Acta 3662.

Journal: The Journal of antibiotics 20090801

Title: Pyripyropenes, fungal sesquiterpenes conjugated with alpha-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells.

Journal: Biological & pharmaceutical bulletin 20090701

Title: 4-Hydr-oxy-3-[(2E)-3-(3,4,5-trimethoxy-phen-yl)prop-2-eno-yl]-2H-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: Rationally improved chiral Brønsted acid for catalytic enantioselective allylboration of aldehydes with an expanded reagent scope.

Journal: The Journal of organic chemistry 20090605

Title: A complex between 6-iodolactone and the peroxisome proliferator-activated receptor type gamma may mediate the antineoplastic effect of iodine in mammary cancer.

Journal: Prostaglandins & other lipid mediators 20090601

Title: Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives.

Journal: European journal of medicinal chemistry 20090501

Title: The human oxidative DNA glycosylase NEIL1 excises psoralen-induced interstrand DNA cross-links in a three-stranded DNA structure.

Journal: The Journal of biological chemistry 20090501

Title: Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation.

Journal: The Journal of antibiotics 20090401

Title: A new pyranone derivative from the leaves of Livistona australis.

Journal: Natural product communications 20090401

Title: 3-Anilinothio-carbonyl-4-hydroxy-chromen-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20090401

Title: Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa.

Journal: Journal of natural products 20090327

Title: Stereoselective synthesis of (-)-spicigerolide.

Journal: The Journal of organic chemistry 20090306

Title: Pyrone derivatives from the marine-derived fungus Nigrospora sp. PSU-F18.

Journal: Phytochemistry 20090301

Title: First synthesis of [1,3,5-(13)C3]gallic acid.

Journal: Organic & biomolecular chemistry 20090221

Title: Syntheses of tricyclic pyrones and pyridinones and protection of Abeta-peptide induced MC65 neuronal cell death.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo.

Journal: Journal of neurochemistry 20090201

Title: Dibenzofuran and pyranone metabolites from Hypericum revolutum ssp. revolutum and Hypericum choisianum.

Journal: Phytochemistry 20090201

Title: 5-Hydr-oxy-2-methyl-4H-pyran-4-one.

Journal: Acta crystallographica. Section E, Structure reports online 20090201

Title: Metabolites from the endophytic mitosporic Dothideomycete sp. LRUB20.

Journal: Phytochemistry 20090101

Title: Antibacterial neurymenolides from the Fijian red alga Neurymenia fraxinifolia.

Journal: Organic letters 20090101

Title: Synthesis of 4-pyridone-3-sulfate and an improved synthesis of 3-hydroxy-4-pyridone.

Journal: Chemistry Central journal 20090101

Title: Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR).

Journal: Molecular cancer 20090101

Title: Trichopyrone and other constituents from the marine sponge-derived fungus Trichoderma sp.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

Title: Tricyclic pyrone compounds prevent aggregation and reverse cellular phenotypes caused by expression of mutant huntingtin protein in striatal neurons.

Journal: BMC neuroscience 20090101

Title: Evolution of metabolic diversity in polyketide-derived pyrones: using the non-colinear aureothin assembly line as a model system.

Journal: Phytochemistry 20090101

Title: Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases.

Journal: PloS one 20090101

Title: Determination of the absolute configurations at stereogenic centers in the presence of axial chirality.

Journal: Chirality 20090101

Title: Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: a new route to pyrano[4,3-c]pyrazol-4(1H)-ones.

Journal: Beilstein journal of organic chemistry 20090101

Title: Poly[(μ-5,7-dihydr-oxy-4-oxo-2-phenyl-4H-chromene-8-sulfonato)potassium(I)].

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: A natural light induced regioselective 6pi-electrocyclisation-oxidative aromatisation reaction: experimental and theoretical insights.

Journal: Organic & biomolecular chemistry 20081221

Title: Rhenium- and manganese-catalyzed insertion of acetylenes into beta-keto esters: synthesis of 2-pyranones.

Journal: Chemical communications (Cambridge, England) 20081221

Title: Phenylnannolones A-C: biosynthesis of new secondary metabolites from the myxobacterium Nannocystis exedens.

Journal: Chembiochem : a European journal of chemical biology 20081215

Title: Synthesis of pluraflavin A 'aglycone'.

Journal: Journal of the American Chemical Society 20081210

Title: Antimycobacterial butanolides from the root of Lindera akoensis.

Journal: Chemistry & biodiversity 20081201

Title: Et3N-induced demethylation-annulation of 3-alkynyl-4-methoxy-2-pyridones and structurally related compounds in the synthesis of furan-fused heterocycles.

Journal: The Journal of organic chemistry 20081107

Title: A concise and modular synthesis of pyranicin.

Journal: Organic letters 20081106

Title: Spatial and temporal clustering of dengue virus transmission in Thai villages.

Journal: PLoS medicine 20081101

Title: A new 24-membered lactone and a new polyene delta-lactone from the marine bacterium Bacillus marinus.

Journal: The Journal of antibiotics 20081101

Title: 2,2,9-Trimethyl-2,3-dihydro-pyrano[2,3-a]carbazol-4-(11H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: The RNA polymerase 'switch region' is a target for inhibitors.

Journal: Cell 20081017

Title: Influence of preparation conditions in the textural and chemical properties of activated carbons from a novel biomass precursor: the coffee endocarp.

Journal: Bioresource technology 20081001

Title: Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida.

Journal: Journal of experimental botany 20081001

Title: The hydration of chloroacetonitriles catalyzed by mono- and dinuclear Ru(II)- and Os(II)-arene complexes.

Journal: Chemistry & biodiversity 20081001

Title: Concise synthesis of spirocyclic, bridged gamma-butyrolactones via stereospecific, dyotropic rearrangements of beta-lactones involving 1,2-acyl and delta-lactone migrations.

Journal: Journal of the American Chemical Society 20080813

Title: Epoxydons and a pyrone from the marine-derived fungus Nigrospora sp. PSU-F5.

Journal: Journal of natural products 20080801

Title: 2-(5,7-Dimeth-oxy-4-oxo-4H-chromen-2-yl)phenyl 4-toluene-sulfonate.

Journal: Acta crystallographica. Section E, Structure reports online 20080801

Title: Rhenium-catalyzed synthesis of multisubstituted aromatic compounds via C-C single-bond cleavage.

Journal: Organic letters 20080717

Title: The toxicity and physiological effect of goniothalamin, a styryl-pyrone, on the generalist herbivore, Spodoptera exigua Hübner.

Journal: Chemosphere 20080701

Title: Lewis acid-Lewis base catalyzed enantioselective hetero-Diels-Alder reaction for direct access to delta-lactones.

Journal: Organic letters 20080515

Title: Bioactive metabolites from the endophytic fungus Ampelomyces sp. isolated from the medicinal plant Urospermum picroides.

Journal: Phytochemistry 20080501

Title: Total synthesis of (-)-kainic acid via intramolecular Michael addition: a second-generation route.

Journal: Organic letters 20080501

Title: Simvastatin prevents the inflammatory process and the dopaminergic degeneration induced by the intranigral injection of lipopolysaccharide.

Journal: Journal of neurochemistry 20080401

Title: Identification of the in vitro metabolites of 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; beta-lapachone) in whole blood.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401

Title: Modular synthesis of candidate indole-based insulin mimics by Claisen rearrangement.

Journal: Organic letters 20080320

Title: Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20080215

Title: Structural determination and proposed biosynthesis of alcanivorone, a novel alpha-pyrone produced by Alcanivorax jadensis.

Journal: The Journal of antibiotics 20080201

Title: Asymmetric synthesis of (+)-altholactone: a styryllactone isolated from various Goniothalamus species.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: [New amphiphilic chlorins in the chlorophyll a series].

Journal: Bioorganicheskaia khimiia 20080101

Title: Testing comparative phylogeographic models of marine vicariance and dispersal using a hierarchical Bayesian approach.

Journal: BMC evolutionary biology 20080101

Title: 8-Meth-oxy-3-(4-methyl-benzyl-idene)-6-(prop-1-en-yl)chroman-4-one.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: 8-Eth-oxy-3-(4-isopropyl-benzyl-idene)-6-methyl-chroman-4-one.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: A two-directional approach to a (-)-dictyostatin C11-C23 segment: development of a highly diastereoselective, kinetically-controlled Meerwein-Ponndorf-Verley reduction.

Journal: Journal of the American Chemical Society 20071226

Title: Vibrational assignments and electronic structure calculations for 3-acetylcoumarin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071101

Title: Structural characterization of schintrilactone, a new class of nortriterpenoids from Schisandra chinensis.

Journal: Organic letters 20071011

Title: A pyran-2-one and four meroterpenoids from Thapsia transtagana and their implication in the biosynthesis of transtaganolides.

Journal: Phytochemistry 20071001

Title: A new pyrone derivative from the endophytic fungus Penicillium paxilli PSU-A71.

Journal: Chemical & pharmaceutical bulletin 20070901

Title: Xylocarpins A and B, two new mexicanolides from the seeds of a Chinese mangrove Xylocarpus granatum: NMR investigation in mixture.

Journal: Magnetic resonance in chemistry : MRC 20070801

Title: Antifungal activity evaluation of the constituents of Haliclona baeri and Haliclona cymaeformis, collected from the Gulf of Thailand.

Journal: Marine drugs 20070601

Title: Active site mutagenesis of the putative Diels-Alderase macrophomate synthase.

Journal: Chemical communications (Cambridge, England) 20070507

Title: Withanolides with phytotoxic activity from Jaborosa caulescens var. caulescens and J. caulescens var. bipinnatifida 1.

Journal: Journal of natural products 20070501

Title: Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase.

Journal: Journal of medicinal chemistry 20070419

Title: Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum.

Journal: Journal of natural products 20070401

Title: De novo approach to 2-deoxy-beta-glycosides: asymmetric syntheses of digoxose and digitoxin.

Journal: The Journal of organic chemistry 20070330

Title: Metabolites from the fungus Cephalosporium sp. AL031.

Journal: Archives of pharmacal research 20070301

Title: Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum.

Journal: Chemico-biological interactions 20070130

Title: Synthesis of spiropyrans: H-abstractions in 3-cycloalkenyloxybenzopyrans.

Journal: Beilstein journal of organic chemistry 20070101

Title: Cytotoxic alpha-pyrones from Xylaria hypoxylon.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101

Title: Anti-inflammatory properties of dietary flavonoids.

Journal: Nutricion hospitalaria 20070101

Title: Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages.

Journal: Mediators of inflammation 20070101

Title: Sex dimorphisms in activated mesenchymal stem cell function.

Journal: Shock (Augusta, Ga.) 20061201

Title: Regiocontrolled intramolecular cyclizations of carboxylic acids to carbon-carbon triple bonds promoted by acid or base catalyst.

Journal: Organic letters 20061123

Title: Structure assignment of lagunapyrone B by fluorous mixture synthesis of four candidate stereoisomers.

Journal: Journal of the American Chemical Society 20061101

Title: Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone.

Journal: The Journal of antibiotics 20061101

Title: Spectroscopic and potentiometric characterization of oxovanadium(IV) complexes formed by 3-hydroxy-4-pyridinones. Rationalization of the influence of basicity and electronic structure of the ligand on the properties of V(IV)O species in aqueous solution.

Journal: Inorganic chemistry 20061002

Title: Efficient total syntheses and structural verification of both diospongins A and B via a common delta-lactone intermediate.

Journal: The Journal of organic chemistry 20060929

Title: A stereoselective synthesis of digitoxin and digitoxigen mono- and bisdigitoxoside from digitoxigenin via a palladium-catalyzed glycosylation.

Journal: Organic letters 20060914

Title: Model complexes of cobalt-substituted matrix metalloproteinases: tools for inhibitor design.

Journal: Inorganic chemistry 20060904

Title: Diastereoselective [4 + 4]-photocycloaddition reactions of pyran-2-ones: rapid access to functionalized 5-8-5 skeletons.

Journal: Organic letters 20060831

Title: Toward the development of a general chiral auxiliary. Enantioselective alkylation and a new catalytic asymmetric addition of silyloxyfurans: application to a total synthesis of (-)-rasfonin.

Journal: Journal of the American Chemical Society 20060830

Title: Total synthesis of myxothiazols, novel bis-thiazole beta-methoxyacrylate-based anti-fungal compounds from myxobacteria.

Journal: Organic & biomolecular chemistry 20060807

Title: Genetically engineered synthesis and structural characterization of cobalt-precorrin 5A and -5B, two new intermediates on the anaerobic pathway to vitamin B12: definition of the roles of the CbiF and CbiG enzymes.

Journal: Journal of the American Chemical Society 20060802

Title: Efficient production of 2-pyrone 4,6-dicarboxylic acid as a novel polymer-based material from protocatechuate by microbial function.

Journal: Applied microbiology and biotechnology 20060801

Title: Manaarenolides A-I, diterpenoids from the soft coral Sinularia manaarensis.

Journal: Journal of natural products 20060801

Title: TD-DFT investigation of the UV spectra of pyranone derivatives.

Journal: The journal of physical chemistry. A 20060706

Title: Bioactive properties of iron-containing carbon monoxide-releasing molecules.

Journal: The Journal of pharmacology and experimental therapeutics 20060701

Title: A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-beta oligomeric complexes.

Journal: Journal of neurochemistry 20060701

Title: Total synthesis of the interleukin-1beta converting enzyme inhibitor EI-1941-2 using tandem oxa-electrocyclization/oxidation1.

Journal: Organic letters 20060622

Title: Bis(allixinato)oxovanadium(IV) complex is a potent antidiabetic agent: studies on structure-activity relationship for a series of hydroxypyrone-vanadium complexes.

Journal: Journal of medicinal chemistry 20060601

Title: Photochemical ring-opening and intramolecular hydrogen shift reactions in sulfur analogues of alpha-pyrone.

Journal: The journal of physical chemistry. A 20060525

Title: Vibronic absorption, fluorescence, and phosphorescence spectra of psoralen: a quantum chemical investigation.

Journal: Physical chemistry chemical physics : PCCP 20060514

Title: Triplet photosensitization in cyercene A and related pyrones.

Journal: Journal of photochemistry and photobiology. B, Biology 20060501

Title: A theoretical insight into the photophysics of psoralen.

Journal: The Journal of chemical physics 20060328

Title: A hetero-Diels-Alder approach to complex pyrones: an improved synthesis of the spongistatin AB spiroketal.

Journal: Organic letters 20060302

Title: Experimental study on the thermal oxidation of 2-chlorophenol in air over the temperature range 450-900 degrees C.

Journal: Chemosphere 20060301

Title: delta-Lactone from Oedogonium capillare and their effects on rat ileum.

Journal: Natural product research 20060301

Title: Synthesis of tyrosinase inhibitory kojic acid derivative.

Journal: Archiv der Pharmazie 20060301

Title: Inhibition of CYP6B1-mediated detoxification of xanthotoxin by plant allelochemicals in the black swallowtail (Papilio polyxenes).

Journal: Journal of chemical ecology 20060301

Title: Eta4-pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs).

Journal: Bioorganic & medicinal chemistry letters 20060215

Title: Acetyltrimethylsilane: a novel reagent for the transformation of 2H-pyran-2-ones to unsymmetrical biaryls.

Journal: The Journal of organic chemistry 20060120

Title: Chip-based polyketide biosynthesis and functionalization.

Journal: Biotechnology progress 20060101

Title: Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors.

Journal: Bioinorganic chemistry and applications 20060101

Title: The Trichoderma koningii aggregate species.

Journal: Studies in mycology 20060101

Title: Preclinical pharmacokinetics and metabolism of a novel prototype DNA-PK inhibitor NU7026.

Journal: British journal of cancer 20051031

Title: Potent, selective pyrone-based inhibitors of stromelysin-1.

Journal: Journal of the American Chemical Society 20051019

Title: Novel and stereocontrolled synthesis of (+/-)-tetrodotoxin from myo-inositol.

Journal: The Journal of organic chemistry 20050916

Title: On the pyrolysis mechanism of 2-pyranones and 2-pyranthiones: thermally induced ground electronic state chemistry of pyran-2-thione.

Journal: The Journal of organic chemistry 20050916

Title: Synthesis of the aglycones of altromycins and kidamycin from a common intermediate.

Journal: Organic letters 20050818

Title: Stereoselective synthesis of c3-c12 dihydropyran portion of antitumor laulimalide using copper-catalyzed oxonium ylide formation-[2,3] shift.

Journal: Chemical & pharmaceutical bulletin 20050801

Title: Koniamborine, the first pyrano[3,2-b]indole alkaloid and other secondary metabolites from Boronella koniambiensis.

Journal: Journal of natural products 20050701

Title: 2-Pyrone natural products and mimetics: isolation, characterisation and biological activity.

Journal: Natural product reports 20050601

Title: Aurovertin E, a new polyene pyrone from the basidiomycete Albatrellus confluens.

Journal: The Journal of antibiotics 20050601

Title: Diastereoselective annulation of 4-hydroxypyran-2H-ones with enantiopure 2,3-dideoxy-alpha,beta-unsaturated sugar aldehydes derived from respective glycals.

Journal: Carbohydrate research 20050523

Title: Synthesis of the putative structure of tridachiahydropyrone.

Journal: Organic letters 20050414

Title: The chafer pheromone buibuilactone and ant pyrazines are also produced by marine bacteria.

Journal: Journal of chemical ecology 20050401

Title: Macrophomate synthase: QM/MM simulations address the Diels-Alder versus Michael-Aldol reaction mechanism.

Journal: Journal of the American Chemical Society 20050316

Title: Applications of the amino-Cope rearrangement: synthesis of tetrahydropyran, delta-lactone and piperidine targets.

Journal: Organic & biomolecular chemistry 20050307

Title: Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation.

Journal: Journal of the American Chemical Society 20050112

Title: 1H chemical shifts in NMR. Part 21--prediction of the 1H chemical shifts of molecules containing the ester group: a modelling and ab initio investigation.

Journal: Magnetic resonance in chemistry : MRC 20050101

Title: A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I.

Journal: The Journal of antibiotics 20050101

Title: Photoreaction of skin-sensitizing trimethyl psoralen with lipid membrane models.

Journal: Photochemistry and photobiology 20050101

Title: Covalent attachment of the plant natural product naringenin to small glass and ceramic beads.

Journal: BMC chemical biology 20050101

Title: Asymmetric total syntheses of (+)-mycoepoxydiene and related natural product (-)-1893A: application of one-pot ring-opening/cross/ring-closing metathesis to construct their 9-oxabicyclo[4.2.1]nona-2,4-diene skeleton.

Journal: The Journal of organic chemistry 20041210

Title: Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity.

Journal: Current medicinal chemistry 20041201

Title: X-ray investigations of bicyclic alpha-methylene-delta-valerolactones. II. (4aS,8aS)-4a-methyl-3-methyleneperhydrochromen-2-one.

Journal: Acta crystallographica. Section C, Crystal structure communications 20041201

Title: Enantioselective catalysis of the hetero-Diels-Alder reaction between Brassard's diene and aldehydes by hydrogen-bonding activation: a one-step synthesis of (S)-(+)-dihydrokawain.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20041119

Title: (4R,4aR,6S,7S,7aS)-6-Hydroxy-7-hydroxymethyl-4-methylperhydrocyclopenta[c]pyran-1-one chloroform solvate from Valeriana laxiflora.

Journal: Acta crystallographica. Section C, Crystal structure communications 20041101

Title: Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.

Journal: Bioorganic & medicinal chemistry 20041015

Title: Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors.

Journal: Journal of medicinal chemistry 20040729

Title: New beginnings for matrix metalloproteinase inhibitors: identification of high-affinity zinc-binding groups.

Journal: Journal of the American Chemical Society 20040714

Title: Interconvertions between delta-lactam and delta-lactone derivatives initiated by unique transannular interactions of the rigid cyclohexane boat structure in pentacycloundecane.

Journal: The Journal of organic chemistry 20040709

Title: Structure of macrophomate synthase.

Journal: Acta crystallographica. Section D, Biological crystallography 20040701

Title: Synthesis of pyran and pyranone natural products.

Journal: Molecules (Basel, Switzerland) 20040531

Title: Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.

Journal: Journal of agricultural and food chemistry 20040519

Title: Facile one-step synthesis of beta-alkoxy lactone via sequential lactonization and 1,4-addition of alkoxide group: total synthesis of all stereoisomers of dihydrokawain-5-ol.

Journal: The Journal of organic chemistry 20040514

Title: Cytotoxic flavonoids and alpha-pyrones from Cryptocarya obovata.

Journal: Journal of natural products 20040501

Title: Formal total synthesis of (-)-apicularen A via transannular conjugate addition.

Journal: Organic letters 20040415

Title: Zooxanthellamide B, a novel large polyhydroxy metabolite from a marine dinoflagellate of Symbiodinium sp.

Journal: Bioscience, biotechnology, and biochemistry 20040401

Title: Stereocontrolled synthesis of the C21-C38 fragment of the unnatural enantiomer of the antibiotic nystatin A1.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040319

Title: Four new stilbenoids from the lianas of Gnetum montanum f. megalocarpum.

Journal: Planta medica 20040201

Title: Analysis of anal secretions from phlaeothripine thrips.

Journal: Journal of chemical ecology 20040201

Title: Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster.

Journal: BMC pharmacology 20040101

Title: Dietary flavonoids and cancer risk: evidence from human population studies.

Journal: Nutrition and cancer 20040101

Title: Complete reduction of 2H-pyran-2-one moiety of coumarin and 6-methyl coumarin by Colletotrichum capsici.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Title: Rhenium-catalyzed coupling of propargyl alcohols and allyl silanes.

Journal: Journal of the American Chemical Society 20031224

Title: Kinetic study of the oxidation of quercetin by mushroom tyrosinase.

Journal: Journal of agricultural and food chemistry 20031217

Title: Novel alpha-pyrones produced by a marine Pseudomonas sp. F92S91: taxonomy and biological activities.

Journal: The Journal of antibiotics 20031201

Title: Viridepyronone, a new antifungal 6-substituted 2H-pyran-2-one produced by Trichoderma viride.

Journal: Journal of agricultural and food chemistry 20031119

Title: Studies on K2CO3-catalyzed 1,4-addition of 1,2-allenic ketones with diethyl malonate: controlled selective synthesis of beta,gamma-unsaturated enones and alpha-pyrones.

Journal: The Journal of organic chemistry 20031114

Title: Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.

Journal: Journal of medicinal chemistry 20031106

Title: Synthesis and photochemistry of isothiocoumarins fused to an additional pyranone or thiopyranone ring.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20031101

Title: Highly diastereoselective hydrogenations leading to beta-hydroxy delta-lactones in hydroxy-protected form. A modified view of delta-lactone conformations.

Journal: Journal of the American Chemical Society 20031001

Title: Placidenes C-F, novel alpha-pyrone propionates from the Mediterranean sacoglossan Placida dendritica.

Journal: Journal of natural products 20031001

Title: Influence of iodide and iodolactones on thyroid apoptosis. Evidence that apoptosis induced by iodide is mediated by iodolactones in intact porcine thyroid follicles.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030901

Title: Novel pyrone side tetracyclic psoralen derivatives: synthesis and photobiological evaluation.

Journal: Journal of medicinal chemistry 20030828

Title: Total synthesis of the antiallergic naphtho-alpha-pyrone tetraglucoside, cassiaside C(2), isolated from cassia seeds.

Journal: The Journal of organic chemistry 20030808

Title: The synthesis of deoxyfusapyrone. 2. Preparation of the bis-trisubstituted olefin fragment and its attachment to the pyrone moiety.

Journal: The Journal of organic chemistry 20030711

Title: 6-Alkyl, alkoxy, or alkylthio-substituted 3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20030707

Title: [The isolation and identification of a new alpha-pyrone from Opuntia dillenii].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030701

Title: Multiple activities of a novel substance, dictyopyrone C isolated from Dictyostelium discoideum, in cellular growth and differentiation.

Journal: Protoplasma 20030601

Title: [Studies on flavonoids of Anaphalis sinica].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030601

Title: On the structure of passifloricin A: asymmetric synthesis of the delta-lactones of (2Z,5S,7R,9S,11S)- and (2Z,5R,7R,9S,11S)tetrahydroxyhexacos-2-enoic acid.

Journal: Organic letters 20030501

Title: Chiral hetero Diels-Alder products by enantioselective and diastereoselective zirconium catalysis. Scope, limitation, mechanism, and application to the concise synthesis of (+)-Prelactone C and (+)-9-deoxygoniopypyrone.

Journal: Journal of the American Chemical Society 20030402

Title: Insight into a natural Diels-Alder reaction from the structure of macrophomate synthase.

Journal: Nature 20030313

Title: Aromatic and pyrone polyketides synthesized by a stilbene synthase from Rheum tataricum.

Journal: Phytochemistry 20030201

Title: Studies on 2'-alpha-C-carboxyalkyl nucleosides and their application to a stereocontrolled nucleobase exchange process.

Journal: Organic & biomolecular chemistry 20030107

Title: [Unusual transformation in a series of native chlorins under the effect of dichlorodicyanbenzquinone].

Journal: Bioorganicheskaia khimiia 20030101

Title: Toxicity of kava pyrones, drug safety and precautions--a case study.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20030101

Title: Efficient nickel-catalyzed [2 + 2 + 2] cycloaddition of CO2 and diynes.

Journal: Journal of the American Chemical Society 20021225

Title: Chelation-controlled reduction: stereoselective formation of syn-1,3-diols and synthesis of compactin and mevinolin lactone.

Journal: The Journal of organic chemistry 20021213

Title: Synthesis of glycosides of 3-deoxy-4-thiopentopyranosid-2-uloses and their reduction products: 3-deoxy-4-thiopentopyranosides.

Journal: Carbohydrate research 20021119

Title: Total synthesis of rhizoxin D, a potent antimitotic agent from the fungus Rhizopus chinensis.

Journal: The Journal of organic chemistry 20021101

Title: Stereocontrolled diels-alder cycloadditions of sugar-derived dihydropyranones with dienes.

Journal: The Journal of organic chemistry 20021101

Title: The synthesis of deoxyfusapyrone. 1. An approach to the pyrone moiety.

Journal: The Journal of organic chemistry 20021101

Title: Molecular characterization of root-specific chalcone synthases from Cassia alata.

Journal: Planta 20021101

Title: Intramolecular reaction of a phenonium ion. Novel lactonization of 4-aryl-5-tosyloxypentanoates and 4-aryl-5-tosyloxyhexanoates concomitant with a phenyl rearrangement.

Journal: The Journal of organic chemistry 20020920

Title: Bis(5-hydroxy-2-hydroxymethyl-4-pyrone-kappa 2O4,O5)bis(2-hydroxymethyl-5-oxido-4-pyrone-kappa 2O4,O5)calcium(II) tetrahydrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20020901

Title: First total syntheses of the phytotoxins solanapyrones D and E via the domino Michael protocol.

Journal: The Journal of organic chemistry 20020823

Title: New monascus metabolite isolated from red yeast rice (angkak, red koji).

Journal: Journal of agricultural and food chemistry 20020703

Title: 2,2-Disubstituted analogues of the natural hormone 1 alpha,25-dihydroxyvitamin D(3): chemistry and biology.

Journal: Bioorganic & medicinal chemistry 20020701

Title: Isolation and structure of a 20,21-epoxybufenolide series from 'Ch'an Su'.

Journal: Journal of natural products 20020701

Title: Three pyrone glucosidic derivatives from Conyza albida.

Journal: Planta medica 20020701

Title: A novel and highly stereoselective approach to aza-spirocycles. A short total synthesis of 2-epi-(+/-)-perhydrohistrionicotoxin and an unprecedented decarboxylation of 2-pyrones.

Journal: Organic letters 20020613

Title: Effect of KOH activation on the formation of oxygen structure in activated carbons synthesized from polymeric precursor.

Journal: Journal of colloid and interface science 20020601

Title: Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020501

Title: Inhibition of yeast lipase (CRL1) and cholesterol esterase (CRL3) by 6-chloro-2-pyrones: comparison with porcine cholesterol esterase.

Journal: Biochimica et biophysica acta 20020429

Title: Catalytic, asymmetric trans-selective hetero Diels-Alder reactions using a chiral zirconium complex.

Journal: Organic letters 20020404

Title: Oxidative degradation of a sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrone in aqueous/organic cosolvent mixtures.

Journal: Pharmaceutical research 20020401

Title: K(2)CO(3)-catalyzed Michael addition-lactonization reaction of 1,2-allenyl ketones with electron-withdrawing group substituted acetates. An efficient synthesis of alpha-pyrone derivatives.

Journal: Organic letters 20020221

Title: The first total synthesis of (+/-)-arisugacin A, a potent, orally bioavailable inhibitor of acetylcholinesterase.

Journal: Organic letters 20020207

Title: Ethyl (6aRS,8RS,12bRS)-6-oxo-8-phenyl-6a,7,8,12b-tetrahydro-6H-benzo[b]naphtho[1,2-d]pyran-6a-carboxylate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20020201

Title: Structure of sch 419560, a novel alpha-pyrone antibiotic produced by Pseudomonas fluorescens.

Journal: The Journal of antibiotics 20020201

Title: NMR and X-ray crystallographic studies of the conformation of a 3,4,6-triphenyl-delta-lactone.

Journal: The Journal of organic chemistry 20020111

Title: Time resolved fluorescence spectroscopy of quercetin and morin complexes with Al3+.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020101

Title: Novel tricyclic pyrone compounds prevent intracellular APP C99-induced cell death.

Journal: Journal of molecular neuroscience : MN 20020101

Title: Behavioral and chemical analysis of venom gland secretion of queens of the ant Solenopsis geminata.

Journal: Journal of chemical ecology 20011201

Title: Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin.

Journal: Journal of molecular biology 20011130

Title: Synthesis and in vitro studies of pyrone derivatives as scavengers of active oxygen species.

Journal: Arzneimittel-Forschung 20011101

Title: Insecticidal compounds from Kalanchoe daigremontiana x tubiflora.

Journal: Phytochemistry 20010901

Title: The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies.

Journal: Chemistry & biology 20010901

Title: NMR determination of the absolute configuration of a macrophomate synthase inhibitor by using an axial chiral reagent.

Journal: Bioscience, biotechnology, and biochemistry 20010801

Title: Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom.

Journal: Bioorganic & medicinal chemistry 20010501

Title: Improved antifungal activity of a mutant of Trichoderma harzianum CECT 2413 which produces more extracellular proteins.

Journal: Applied microbiology and biotechnology 20010501

Title: Pyrone and pyridone compounds in the liquid culture of Physisporinus sanguinolentus.

Journal: Phytochemistry 20010401

Title: Effects of 2,3-diketo-L-gulonic acid on the oxidation of yolk lipoprotein.

Journal: Bioscience, biotechnology, and biochemistry 20010301

Title: The first total synthesis of (-)-solanapyrone E based on domino Michael strategy.

Journal: Organic letters 20010125

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