Home Other Building Blocks 5041-81-6
5041-81-6,MFCD00272145
Catalog No.:AA003R15

5041-81-6 | Isoliquiritin

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5mg
≥98%
in stock  
$255.00   $178.00
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10mg
≥98%
in stock  
$456.00   $319.00
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20mg
in stock  
$504.00   $353.00
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50mg
≥98%
in stock  
$1,133.00   $793.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003R15
Chemical Name:
Isoliquiritin
CAS Number:
5041-81-6
Molecular Formula:
C21H22O9
Molecular Weight:
418.3940
MDL Number:
MFCD00272145
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)/C=C/C(=O)c2ccc(cc2O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Properties
 
Form:
Solid  
MP:
185-186℃  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
589  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
6  
XLogP3:
1.7  

Literature

Title: Comparative analysis of the main bioactive components of San-ao decoction and its series of formulations.

Journal: Molecules (Basel, Switzerland) 20121101

Title: Construction of an Indonesian herbal constituents database and its use in Random Forest modelling in a search for inhibitors of aldose reductase.

Journal: Bioorganic & medicinal chemistry 20120201

Title: Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080701

Title: Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages.

Journal: European journal of pharmacology 20080414

Title: [Selective adsorption of multi-walled carbon nanotubes with liquiritin and isoliquiritin].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071101

Title: Orthogonal array design for optimizing extraction efficiency of active constituents from Jakyak-Gamcho Decoction, the complex formula of herbal medicines, Paeoniae Radix and Glycyrrhizae Radix.

Journal: Journal of ethnopharmacology 20070905

Title: Separation of Liquiritin by simulated moving bed chromatography.

Journal: Journal of chromatography. A 20070323

Title: Anti-human immunodeficiency virus phenolics from licorice.

Journal: Chemical & pharmaceutical bulletin 19880601

Title: Kobayashi S, et al. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biol Pharm Bull. 1995 Oct;18(10):1382-6.

Title: Wang W, et al. Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1179-84.

Title: Luo J, et al. Antifungal Activity of Isoliquiritin and Its Inhibitory Effect against Peronophythora litchi Chen through a Membrane Damage Mechanism. Molecules. 2016 Feb 19;21(2):237.

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