Home Amines 5049-61-6
5049-61-6,MFCD00006137
Catalog No.:AA003GH5

5049-61-6 | Pyrazin-2-amine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10g
98%
in stock  
$6.00   $4.00
- +
25g
98%
in stock  
$8.00   $6.00
- +
100g
98%
in stock  
$26.00   $18.00
- +
500g
98%
in stock  
$128.00   $89.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003GH5
Chemical Name:
Pyrazin-2-amine
CAS Number:
5049-61-6
Molecular Formula:
C4H5N3
Molecular Weight:
95.1026
MDL Number:
MFCD00006137
SMILES:
Nc1cnccn1
NSC Number:
13147
Properties
Properties
 
BP:
250.905°C at 760 mmHg  
Form:
Solid  
MP:
118-120 °C(lit.)  
Refractive Index:
1.5200 (estimate)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
54.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
-0.1  

Literature

Title: Solvation effect on the NH stretching vibrations of solvated aminopyrazine, 2-aminopyridine, and 3-aminopyridine clusters.

Journal: The journal of physical chemistry. A 20120920

Title: Carboxylic acid functionalized ortho-linked oxacalix[2]benzene[2]pyrazine: synthesis, structure, hydrogen bond and metal directed self-assembly.

Journal: Dalton transactions (Cambridge, England : 2003) 20120514

Title: Diaqua-bis-(pyrazine-2-carboxamide-κ(2)N(1),O)cobalt(II) dinitrate.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: The discovery of aminopyrazines as novel, potent Na(v)1.7 antagonists: hit-to-lead identification and SAR.

Journal: Bioorganic & medicinal chemistry letters 20120301

Title: catena-Poly[[diiodidomercury(II)]-μ(2)-2-amino-pyrazine-κN:N].

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: Nine non-symmetric pyrazine-pyridine imide-based complexes: reversible redox and isolation of [M(II/III)(pypzca)2](0/+) when M = Co, Fe.

Journal: Dalton transactions (Cambridge, England : 2003) 20120207

Title: Diaqua-bis-[5-(pyrazin-2-yl)-3-(pyridin-4-yl)-1H-1,2,4-triazol-1-ido-κN]zinc.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells.

Journal: Stem cell research & therapy 20120101

Title: Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing.

Journal: Journal of medicinal chemistry 20111222

Title: Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.

Journal: Bioorganic & medicinal chemistry letters 20111001

Title: Spin canting and metamagnetism in 2D and 3D cobalt(II) coordination networks with alternating double end-on and double end-to-end azido bridges.

Journal: Inorganic chemistry 20110801

Title: Bis(2-amino-pyrazine-κN)dichlorido-zinc.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: trans-Bis(acetato-κO)diaquabis-(2-amino-pyrazine-κN)manganese(II) dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: Paramagnetic oxotungsten(V) complexes containing the hydrotris(3,5-dimethylpyrazol-1-yl)borate ligand.

Journal: Inorganic chemistry 20110516

Title: Bis(2-amino-3-carb-oxy-pyrazin-1-ium) sulfate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110301

Title: 2-Amino-3-carb-oxy-pyrazin-1-ium nitrate monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Bis(2,3,5,6-tetra-2-pyridyl-pyrazine-κN,N,N)nickel(II) dithio-cyanate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Identification of AKN-032, a novel 2-aminopyrazine tyrosine kinase inhibitor, with significant preclinical activity in acute myeloid leukemia.

Journal: Biochemical pharmacology 20101115

Title: Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.

Journal: Journal of medicinal chemistry 20101111

Title: [μ-2,3,5,6-Tetra-kis(2-pyrid-yl)pyrazine-κN,N,N:N,N,N]bis-[diaqua(dihydrogen m-phenylene-diphospho-nato-κO)nickel(II)] dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Bis(2-amino-4-methyl-pyrimidin-3-ium) trans-diaqua-bis-(pyrazine-2,3-di-car-boxylato)cobaltate(II) hexa-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Water-induced reversible structural phase transformation with chromotropism in metal supramolecular frameworks containing aminopyrazine and sulfate anions.

Journal: Dalton transactions (Cambridge, England : 2003) 20100921

Title: Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors.

Journal: European journal of medicinal chemistry 20100901

Title: Bis[diamminesilver(I)] 5-nitro-iso-phthalate monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Bis(2,3,5,6-tetra-2-pyridylpyrazine-κN,N,N)iron(II) bis-(dicyanamidate) 4.5-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100301

Title: Platinum(II) and palladium(II) metallomacrocycles derived from cationic 4,4'-bipyridinium, 3-aminopyrazinium and 2-aminopyrimidinium ligands.

Journal: Dalton transactions (Cambridge, England : 2003) 20100107

Title: Dipyrazinyl sulfoxide complexes of silver(I), zinc(II), and cadmium(II): ligation modes and anion tuning.

Journal: Inorganic chemistry 20100104

Title: 3-Amino-1-methyl-pyrazin-1-ium iodide.

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: 3-Amino-1-methyl-pyrazin-1-ium chloride.

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: Excited-state coordination chemistry: excited-state basicity of bis(2,2'-bipyridyl)(2,3-dipyridylpyrazine)ruthenium(II).

Journal: The journal of physical chemistry. A 20091203

Title: Poly[bis(mu2-2-aminopyrazine-kappa2N1:N4)(mu2-nitrato-kappa2O:O)(nitrato-kappa2O,O')disilver(I)]: an achiral two-dimensional coordination polymer forming chiral crystals.

Journal: Acta crystallographica. Section C, Crystal structure communications 20091201

Title: Tetra-kis(2-amino-pyrazine-κN)dichlorido-cobalt(II).

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Hexaaqua-cobalt(II) tetra-aqua-bis(2-amino-pyrazine-κN)cobalt(II) disulfate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Hexaaqua-manganese(II) tetra-aqua-bis(2-amino-pyrazine-κN)manganese(II) disulfate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Coordination complexes with the redox active tetrathiafulvalene based imino-pyrazine ligand: syntheses, a radical cation salt, crystal structures and electrochemistry.

Journal: Dalton transactions (Cambridge, England : 2003) 20090514

Title: Binding catalysis and inhibition by metal ions and protons in the enolization of phenylacetylpyrazine.

Journal: The Journal of organic chemistry 20090501

Title: Aqua-(2,2'-bipyrid-yl)(pyrazine-2,6-dicarboxyl-ato)nickel(II) 1.25-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: N-(Pyrazin-2-yl)aniline.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: catena-Poly[[aqua-(pyrazino[2,3-f][1,10]phenanthroline-κN,N)cobalt(II)]-μ-pyrazine-2,3-dicarboxyl-ato-κNO:O].

Journal: Acta crystallographica. Section E, Structure reports online 20080901

Title: Identification of low molecular weight carbohydrates employing new binary mixtures for matrix-assisted laser desorption/ionisation mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20080701

Title: Aminopyrazine CB1 receptor inverse agonists.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Poly[mu-2-aminopyrazine-kappa2N1:N4-mu-cyanido-copper(I)]: a three-dimensional network from laboratory powder diffraction data.

Journal: Acta crystallographica. Section C, Crystal structure communications 20080301

Title: Ligand effects on the structures and magnetic properties of tricyanomethanide-containing copper(II) complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20071128

Title: Copper(I) cyanide networks: synthesis, luminescence behavior and thermal analysis. Part 1. Diimine ligands.

Journal: Inorganic chemistry 20071015

Title: Synthesis of some new anils: part 1. Reaction of 2-hydroxy-benzaldehyde and 2-hydroxynaphthaldehyde with 2-aminopyridene and 2-aminopyrazine.

Journal: Molecules (Basel, Switzerland) 20070813

Title: Synthesis and spectroscopic characterization of copper(II) tetraazaiminooxime macrocyclic complexes--a tetragonal distortion analysis.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061101

Title: New discrete and polymeric supramolecular architectures derived from dinuclear (bis-beta-diketonato)copper(II) metallocycles.

Journal: Dalton transactions (Cambridge, England : 2003) 20060907

Title: Novel reaction of N,N'-bisarylmethanediamines with formaldehyde. Synthesis of some new 1,3,5-triaryl-1,3,5-hexahydrotriazines.

Journal: Molecules (Basel, Switzerland) 20060726

Title: Conformational behavior of pyrazine-bridged and mixed-bridged cavitands: a general model for solvent effects on thermal 'vase-kite' switching.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20060614

Title: Chiral aggregation and spontaneous resolution of thiosemicarbazone metal complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20060607

Title: New heterocyclic analogues of 4-(2-chloro-5-methoxyanilino)quinazolines as potent and selective c-Src kinase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20051215

Title: Reduced flavin: NMR investigation of N5-H exchange mechanism, estimation of ionisation constants and assessment of properties as biological catalyst.

Journal: BMC biochemistry 20050101

Title: Discovery and validation of a new family of antioxidants: the aminopyrazine derivatives.

Journal: Mini reviews in medicinal chemistry 20040501

Title: Coelenterazine: a two-stage antioxidant in lipid micelles.

Journal: Free radical biology & medicine 20040201

Title: 2-pyrazinylnitrene and 4-pyrimidylnitrene. Ring expansion to 1,3,5-triazacyclohepta-1,2,4,6-tetraene and ring opening to (2-Isocyanovinyl)carbodiimide.

Journal: The Journal of organic chemistry 20021129

Title: Chemistry of stable iminopropadienones, RN=C=C=C=O.

Journal: The Journal of organic chemistry 20020419

Title: Catechol derivatives of aminopyrazine and cell protection against UVB-induced mortality.

Journal: Bioorganic & medicinal chemistry 20010401

Title: Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.

Journal: Biochemical pharmacology 19940817

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:5049-61-6 Molecular Formula|5049-61-6 MDL|5049-61-6 SMILES|5049-61-6 Pyrazin-2-amine |Organic_Building_Blocks