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51-56-9,MFCD00012676
Catalog No.:AA00I925

51-56-9 | Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide

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250mg
95%
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$32.00   $23.00
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1g
95%
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$80.00   $56.00
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5g
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$189.00   $133.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I925
Chemical Name:
Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide
CAS Number:
51-56-9
Molecular Formula:
C16H22BrNO3
Molecular Weight:
356.2548
MDL Number:
MFCD00012676
SMILES:
OC(c1ccccc1)C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)N2C.Br
Properties
Computed Properties
 
Complexity:
340  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Optimization of the Ocular Treatment Following Organophosphate Nerve Agent Insult.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170901

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Acute anterior uveitis following zoledronic acid infusion for osteoporosis.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20121001

Title: Efficacy of tropicamide, homatropine, cyclopentolate, atropine and hyoscine as mydriatics in Angora goats.

Journal: New Zealand veterinary journal 20111101

Title: Bilateral microbial keratitis in highly active antiretroviral therapy-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: a case series.

Journal: Ocular immunology and inflammation 20111001

Title: Comparing homatropine and atropine in pediatric cycloplegic refractions.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20110601

Title: Topical chloramphenicol prophylaxis is of dubious benefit in corneal abrasion.

Journal: Emergency medicine Australasia : EMA 20110401

Title: Is homatropine 5% effective in reducing pain associated with corneal abrasion when compared with placebo? A randomized controlled trial.

Journal: Emergency medicine Australasia : EMA 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Inhibitory effect of anticholinergics on the contraction of isolated caprine urinary bladder detrusor muscle.

Journal: Autonomic & autacoid pharmacology 20100701

Title: The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism.

Journal: Journal of neurochemistry 20100301

Title: Syphilitic palmoplantar keratoderma and ocular disease: a rare combination in an HIV-positive patient.

Journal: Cutis 20091201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Role of the bed nucleus of the stria terminalis in the cardiovascular responses to acute restraint stress in rats.

Journal: Stress (Amsterdam, Netherlands) 20090501

Title: Peripheral ulcerative keratitis with bilateral optic nerve involvement as an initial presentation of acute lymphocytic leukemia in an adult.

Journal: International ophthalmology 20090201

Title: Two differing presentations of chronic bilateral anterior uveitis.

Journal: Optometry (St. Louis, Mo.) 20090201

Title: Granuloma annulare anterior uveitis.

Journal: Ocular immunology and inflammation 20080101

Title: Capillary electrophoresis of tropane alkaloids and glycoalkaloids occurring in Solanaceae plants.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Hypotony maculopathy in a patient with HLA-B27-associated uveitis.

Journal: Ocular immunology and inflammation 20080101

Title: True moving bed electrophoresis using stepped electric field gradients.

Journal: Electrophoresis 20070501

Title: Pretreating rats with parenteral ophthalmic antimuscarinic agents decreases mortality from lethal organophosphate poisoning.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20070401

Title: Increasing the scale of true moving bed electrophoretic separations using filtration to reduce solvent volumetric flows between sections II and III.

Journal: Journal of chromatography. A 20070105

Title: Acute retinal necrosis complicating chickenpox in a healthy adult--a case report and review of literature.

Journal: Comprehensive therapy 20070101

Title: Intramuscular ophthalmic homatropine vs. atropine to prevent lethality in rates with dichlorvos poisoning.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20061201

Title: Homatropine and psychosis in Weill-Marchesani syndrome.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Evaluation of amniotic membrane transplantation as an adjunct to medical therapy as compared with medical therapy alone in acute ocular burns.

Journal: Ophthalmology 20051101

Title: Dense membrane formation after combined phacoemulsification-trabeculectomy surgery.

Journal: Clinical & experimental ophthalmology 20050601

Title: Acute posterior multifocal placoid pigment epitheliopathy after meningococcal C conjugate vaccine.

Journal: Clinical & experimental ophthalmology 20050401

Title: Frontotemporal dementia with co-occurrence of astrocytic plaques and tufted astrocytes, and severe degeneration of the cerebral white matter: a variant of corticobasal degeneration?

Journal: Acta neuropathologica 20050301

Title: Familial HLA-A2- and HLA-B7-associated anterior uveitis.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20041001

Title: Multifocal choroiditis--an unusual finding in Crohn's disease.

Journal: European journal of ophthalmology 20040101

Title: Tubulointerstitial nephritis and uveitis syndrome.

Journal: Optometry (St. Louis, Mo.) 20030401

Title: Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteers.

Journal: Psychopharmacology 20030101

Title: Microbial keratitis and vision loss with contact lenses.

Journal: Eye & contact lens 20030101

Title: Bilateral panuveitis in a child with hypohidrotic ectodermal dysplasia.

Journal: American journal of ophthalmology 20020901

Title: [Effect of pilocarpine and cycloplegic substances on ophthalmic tone in healthy eyes and ones with glaucoma].

Journal: Vestnik oftalmologii 20020101

Title: Contact allergy to atropine and other mydriatic agents in eye drops.

Journal: Contact dermatitis 20011101

Title: [Neurological manifestations in the intoxication of infants by dimethicone combined with homatropine: report of 6 cases].

Journal: Arquivos de neuro-psiquiatria 20010601

Title: Tris(2,2'-bipyridine)ruthenium(II) electrogenerated chemiluminescence of alkaloid type drugs with solid phase extraction sample preparation.

Journal: The Analyst 20010101

Title: Herpes simplex virus type 1 associated acute retinal necrosis following encephalitis.

Journal: Retina (Philadelphia, Pa.) 20010101

Title: Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases.

Journal: The Journal of neuropsychiatry and clinical neurosciences 19920101

Title: Leung, E. and F. Mitchelson, Modification by hexamethonium of the muscarinic receptors blocking activity of pancuronium and homatropine in isolated tissues of the guinea-pig. Eur J Pharmacol, 1982. 80(1): p. 11-7.

Title: Gilani, S.A. and L.B. Cobbin, Interaction of himbacine with carbachol at muscarinic receptors of heart and smooth muscle. Arch Int Pharmacodyn Ther, 1987. 290(1): p. 46-53.

Title: Cramer, M.B., L.A. Cates, and D.E. Clarke, Rectal absorption of homatropine 4Cmethylbromide in the rat. J Pharm Pharmacol, 1978. 30(5): p. 284-6.

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SDS
Tags:51-56-9 Molecular Formula|51-56-9 MDL|51-56-9 SMILES|51-56-9 Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide