51-85-4,MFCD01002952
Catalog No.:AA00DVMV

51-85-4 | 2,2'-Disulfanediyldiethanamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$130.00   $91.00
- +
5g
95%
in stock  
$412.00   $289.00
- +
10g
96%
in stock  
$774.00   $542.00
- +
25g
95%
in stock  
$1,443.00   $1,010.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DVMV
Chemical Name:
2,2'-Disulfanediyldiethanamine
CAS Number:
51-85-4
Molecular Formula:
C4H12N2S2
Molecular Weight:
152.2815
MDL Number:
MFCD01002952
SMILES:
NCCSSCCN
Properties
Properties
 
BP:
106-108 °C(Press: 5 Torr)  
Form:
Liquid  
MP:
135-136 °C  
Refractive Index:
1.5605 (estimate)  
Storage:
Room Temperature;Light sensitive;Inert atmosphere;  

Computed Properties
 
Complexity:
37  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1  

Downstream Synthesis Route

[1]ChemischesZentralblatt,1907,vol.78,p.1156

[1]JournaloftheChemicalSociety,1954,p.1171,1176

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[2]Schoeberl[Hoppe-Seyler'sZeitschriftfurPhysiologischeChemie,1933,vol.216,p.196]

[3]CurrentPatentAssignee:ROCHEHOLDINGAG-DE1000391,1957,BViscontinietal.[HelveticaChimicaActa,1953,vol.36,p.835]

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51-85-4    583-47-1   
2-Amino-N-2-(2-amino-ethyldisulfanyl)-ethyl-3-phenyl-propionamide 

[1]BulletinoftheAcademyofSciencesoftheUSSRDivisionofChemicalScience,1967,p.317-323    IzvestiyaAkademiiNaukSSSR,SeriyaKhimicheskaya,1967,p.334-341

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Title: Selenium functionalized intraocular lenses inhibit posterior capsule opacification in an ex vivo canine lens capsular bag assay.

Journal: Experimental eye research 20091101

Title: Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages.

Journal: Bioconjugate chemistry 20091101

Title: Sulfur metabolism in AIDS: cystamine as an anti-HIV agent.

Journal: AIDS research and human retroviruses 20091101

Title: Biotinylated disulfide containing PEI/avidin bioconjugate shows specific enhanced transfection efficiency in HepG2 cells.

Journal: Organic & biomolecular chemistry 20091021

Title: Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091015

Title: Involvement of tissue transglutaminase in endothelin 1-induced hypertrophy in cultured neonatal rat cardiomyocytes.

Journal: Hypertension (Dallas, Tex. : 1979) 20091001

Title: Identification of a novel small molecule HIF-1alpha translation inhibitor.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091001

Title: Functional delivery of siRNA in mice using dendriworms.

Journal: ACS nano 20090922

Title: Identification and quantitation of Bacillus globigii using metal enhanced electrochemical detection and capillary biosensor.

Journal: Analytical chemistry 20090915

Title: N-propionyl-cysteaminylphenol-magnetite conjugate (NPrCAP/M) is a nanoparticle for the targeted growth suppression of melanoma cells.

Journal: The Journal of investigative dermatology 20090901

Title: Targeting murine heart and brain: visualisation conditions for multi-pinhole SPECT with (99m)Tc- and (123)I-labelled probes.

Journal: European journal of nuclear medicine and molecular imaging 20090901

Title: Application of a biodegradable macromolecular contrast agent in dynamic contrast-enhanced MRI for assessing the efficacy of indocyanine green-enhanced photothermal cancer therapy.

Journal: Journal of magnetic resonance imaging : JMRI 20090801

Title: Polyhydroxylalkyleneamines: a class of hydrophilic cationic polymer-based gene transfer agents.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20090701

Title: Folate deficiency induces neural stem cell apoptosis by increasing homocysteine in vitro.

Journal: Journal of clinical biochemistry and nutrition 20090701

Title: Synthesis and characterization of new ferrocene peptide conjugates.

Journal: Dalton transactions (Cambridge, England : 2003) 20090614

Title: Disulfide-crosslinked electrospun poly(gamma-glutamic acid) nonwovens as reduction-responsive scaffolds.

Journal: Macromolecular bioscience 20090611

Title: Biological and magnetic contrast evaluation of shape-selective Mn-Fe nanowires.

Journal: IEEE transactions on nanobioscience 20090601

Title: Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1.

Journal: Gastroenterology 20090501

Title: Structure of pig heart citrate synthase at 1.78 A resolution.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20090501

Title: PMMA biosensor for nucleic acids with integrated mixer and electrochemical detection.

Journal: Biosensors & bioelectronics 20090415

Title: Surface IR applied to rapid and direct immunosensing of environmental pollutants.

Journal: Talanta 20090415

Title: Homocysteine-induced toxicity increases TG2 expression in Neuro2a cells.

Journal: Amino acids 20090401

Title: Cystamine attenuates the expressions of NOS- and TLR-associated molecules in the brain of NZB/W F1 mice.

Journal: European journal of pharmacology 20090401

Title: Expression of tissue-type transglutaminase (tTG) and the effect of tTG inhibitor on the hippocampal CA1 region after transient ischemia in gerbils.

Journal: Brain research 20090331

Title: Myenteric neuronal loss in rats with experimental colitis: role of tissue transglutaminase-induced apoptosis.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090301

Title: Oxidation of Cys278 of ADH I isozyme from Kluyveromyces lactis by naturally occurring disulfides causes its reversible inactivation.

Journal: Biochimica et biophysica acta 20090301

Title: Optical properties and application of a reactive and bioreducible thiol-containing tetramethylrhodamine dimer.

Journal: Bioconjugate chemistry 20090301

Title: Depletion of nucleophosmin via transglutaminase 2 cross-linking increases drug resistance in cancer cells.

Journal: Cancer letters 20090218

Title: Degradable nanogels as a nanoreactor for growing silica colloids.

Journal: Langmuir : the ACS journal of surfaces and colloids 20090217

Title: Glucosamine is an effective chemo-sensitizer via transglutaminase 2 inhibition.

Journal: Cancer letters 20090118

Title: Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits.

Journal: Brain research 20090116

Title: Increased expression of Matrix Metalloproteinase 9 in liver from NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein.

Journal: Journal of biomedical science 20090101

Title: Silencing of TGase 2 sensitizes breast cancer cells to apoptosis by regulation of survival factors.

Journal: Frontiers in bioscience (Landmark edition) 20090101

Title: Calculating CVD risk in older patients.

Journal: The Practitioner 20090101

Title: Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties.

Journal: PloS one 20090101

Title: Plasma homocysteine is adversely associated with glomerular filtration rate in asymptomatic black and white young adults: the Bogalusa heart study.

Journal: European journal of epidemiology 20090101

Title: Serotonylation of vascular proteins important to contraction.

Journal: PloS one 20090101

Title: Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy.

Journal: Journal of biomedicine & biotechnology 20090101

Title: Doxorubicin loaded Polymeric Nanoparticulate Delivery System to overcome drug resistance in osteosarcoma.

Journal: BMC cancer 20090101

Title: Advances and prospect of nanotechnology in stem cells.

Journal: Nanoscale research letters 20090101

Title: A novel piezoelectric quartz crystal immnuosensor based on hyperbranched polymer films for the detection of alpha-Fetoprotein.

Journal: Analytica chimica acta 20081207

Title: Enhancement of electrochemical signal on gold electrodes by polyvalent esterase-dendrimer clusters.

Journal: Bioconjugate chemistry 20081201

Title: Tunable redox-responsive hybrid nanogated ensembles.

Journal: Journal of the American Chemical Society 20081105

Title: Cystamine prevents haloperidol-induced decrease of BDNF/TrkB signaling in mouse frontal cortex.

Journal: Journal of neurochemistry 20081101

Title: The role of physical activity level and B-vitamin status on blood homocysteine levels.

Journal: Medicine and science in sports and exercise 20081101

Title: ATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.

Journal: The FEBS journal 20081101

Title: A new synthesis of cystamine modified Eu3+ DOTAM-Gly-Phe-OH: a conjugation ready temperature sensitive MRI contrast agent.

Journal: Organic & biomolecular chemistry 20081007

Title: Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles.

Journal: Biomacromolecules 20081001

Title: Highly sensitive electrochemical detection of immunospecies based on combination of Fc label and PPD film/gold nanoparticle amplification.

Journal: Biosensors & bioelectronics 20080915

Title: Beneficial effects of treatment with cystamine on brain in NZB/W F1 mice.

Journal: European journal of pharmacology 20080904

Title: Drastically decreased reactivity of thiols and disulfides complexed by cucurbit[6]uril.

Journal: Organic letters 20080904

Title: Characterization of mixed self-assembled monolayers for immobilization of streptavidin using chemical force microscopy.

Journal: Ultramicroscopy 20080901

Title: The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure.

Journal: PLoS pathogens 20080901

Title: Method for determination of total cysteamine in human plasma by high performance capillary electrophoresis with acetonitrile stacking.

Journal: Electrophoresis 20080901

Title: Sensitivity enhancement by Au nanoparticles in surface plasmon resonance chemical sensors.

Journal: Journal of nanoscience and nanotechnology 20080901

Title: Novel poly(amido amine)s with bioreducible disulfide linkages in their diamino-units: structure effects and in vitro gene transfer properties.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20080825

Title: Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080801

Title: Vasoconstrictor effect of aldosterone via angiotensin II type 1 (AT1) receptor: possible role of AT1 receptor dimerization.

Journal: Cardiovascular research 20080701

Title: Transglutaminase-catalyzed transamidation: a novel mechanism for Rac1 activation by 5-hydroxytryptamine2A receptor stimulation.

Journal: The Journal of pharmacology and experimental therapeutics 20080701

Title: Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes.

Journal: Diabetologia 20080701

Title: EPR characterization of gadolinium(III)-containing-PAMAM-dendrimers in the absence and in the presence of paramagnetic probes.

Journal: Journal of colloid and interface science 20080615

Title: The effect of guanylate cyclase inhibitors on non-adrenergic and non-cholinergic neurogenic relaxations of the South American opossum lower esophageal sphincter.

Journal: Fundamental & clinical pharmacology 20080601

Title: Synthesis and swelling properties of novel pH-sensitive poly(aspartic acid) gels.

Journal: Acta biomaterialia 20080501

Title: Toxins from cone snails: properties, applications and biotechnological production.

Journal: Applied microbiology and biotechnology 20080501

Title: Transglutaminase 2 and NF-kappaB interplay during NGF-induced differentiation of neuroblastoma cells.

Journal: Brain research 20080501

Title: Disulfide S-monoxides convert xanthine dehydrogenase into oxidase in rat liver cytosol more potently than their respective disulfides.

Journal: Biological & pharmaceutical bulletin 20080501

Title: Pulse radiolysis studies on reactions of hydroxyl radicals with selenocystine derivatives.

Journal: The journal of physical chemistry. B 20080410

Title: Malondialdehyde, a lipid-derived aldehyde alters the reactivity of Cys34 and the esterase activity of serum albumin.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080401

Title: No association between global leukocyte DNA methylation and homocysteine levels in schizophrenia patients.

Journal: Schizophrenia research 20080401

Title: Treatment with cystamine reduces apoptosis in liver from NZB/W F1 mice.

Journal: International immunopharmacology 20080401

Title: Cystamine restores GSTA3 levels in Vanin-1 null mice.

Journal: Free radical biology & medicine 20080315

Title: Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease.

Journal: Biochimica et biophysica acta 20080301

Title: A label-free biosensor based on gold nanoshell monolayers for monitoring biomolecular interactions in diluted whole blood.

Journal: Biosensors & bioelectronics 20080227

Title: Transglutaminase inhibitor cystamine alleviates the abnormality in liver from NZB/W F1 mice.

Journal: European journal of pharmacology 20080128

Title: Cystamine prevents ischemia-reperfusion injury by inhibiting polyamination of RhoA.

Journal: Biochemical and biophysical research communications 20080118

Title: Hyaluronic acid induces transglutaminase II to enhance cell motility; role of Rac1 and FAK in the induction of transglutaminase II.

Journal: Biotechnology letters 20080101

Title: Structure and function of A41, a vaccinia virus chemokine binding protein.

Journal: PLoS pathogens 20080101

Title: [Protective action of radioprotectors and shielding against high-energy protons in experiments with rats].

Journal: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20080101

Title: Effect of disulfide-containing compounds on the Na+ transport in the frog skin.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101

Title: Resolution of complex fluorescence spectra of lipids and nicotinic acetylcholine receptor by multivariate analysis reveals protein-mediated effects on the receptor's immediate lipid microenvironment.

Journal: PMC biophysics 20080101

Title: The physiological role of the Gomori-positive glia: a new hypothesis.

Journal: Folia medica Cracoviensia 20080101

Title: Nickel-cysteine binding supported by phosphine chelates.

Journal: Inorganic chemistry 20071029

Title: ATP-mediated mineralization of MC3T3-E1 osteoblast cultures.

Journal: Bone 20071001

Title: Studies on the reducing systems for plant and animal thioredoxin-independent methionine sulfoxide reductases B.

Journal: Biochemical and biophysical research communications 20070928

Title: Ultrasensitive detection of enzymatic activity with nanowire electrodes.

Journal: Journal of the American Chemical Society 20070919

Title: [Long-term follow-up of ofloxacin-combined therapy for leprosy patients].

Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20070901

Title: Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase.

Journal: World journal of gastroenterology 20070828

Title: Thiolato-bridged RuIIAgIRuII trinuclear complex composed of bis(bipyridine)ruthenium(II) units with chelating 2-aminoethanethiolate: conversion to a disulfide-bridged RuIIRuII dinuclear complex.

Journal: Inorganic chemistry 20070820

Title: Facile synthetic procedure for omega, primary amine functionalization directly in water for subsequent fluorescent labeling and potential bioconjugation of RAFT-synthesized (co)polymers.

Journal: Biomacromolecules 20070801

Title: Cellular thiol pools are responsible for sequestration of cytotoxic reactive aldehydes: central role of free cysteine and cysteamine.

Journal: Brain research 20070716

Title: Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.

Journal: Toxicology and applied pharmacology 20070715

Title: Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1.

Journal: Neuroscience letters 20070608

Title: The construction of 3D-engineered tissues composed of cells and extracellular matrices by hydrogel template approach.

Journal: Biomaterials 20070601

Title: RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker alpha(v) beta3 integrin with MRT, mapping.

Journal: International journal of nanomedicine 20070601

Title: Proteomic analysis of high-molecular-weight protein polymers in a doxorubicin-resistant breast-cancer cell line.

Journal: Proteomics. Clinical applications 20070601

Title: Stable supply of large amounts of human Fab from the inclusion bodies in E. coli.

Journal: Journal of biochemistry 20070501

Title: Surface studies of aminoferrocene derivatives on gold: electrochemical sensors for chemical warfare agents.

Journal: Analytical chemistry 20070401

Title: PbnI4n+2(2n+2)- ribbons (n = 3, 5) as dimensional reductions of 2D perovskite layers in cystamine cation based hybrids, also incorporating iodine molecules or reversible guest water molecules.

Journal: Dalton transactions (Cambridge, England : 2003) 20070307

Title: Osteopontin promotes pathologic mineralization in articular cartilage.

Journal: Matrix biology : journal of the International Society for Matrix Biology 20070301

Title: Differential tumor cell targeting of anti-HER2 (Herceptin) and anti-CD20 (Mabthera) coupled nanoparticles.

Journal: International journal of pharmaceutics 20070301

Title: Diagnosis of tularemia using piezoelectric biosensor technology.

Journal: Talanta 20070215

Title: Beneficial effects of treatment with transglutaminase inhibitor cystamine on macrophage response in NZB/W F1 mice.

Journal: Experimental biology and medicine (Maywood, N.J.) 20070201

Title: Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor.

Journal: European journal of immunology 20070201

Title: Methylenetetrahydrofolate reductase gene polymorphism and its association with coronary artery disease.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20070104

Title: Diphenic acid as a general conformational lock in the design of bihelical structures.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans.

Journal: PloS one 20070101

Title: Chronic cystamine treatment inhibits small artery remodelling in rats.

Journal: Journal of vascular research 20070101

Title: [Comparative protective action of radiorotectors and shielding in gamma-irradiated mice].

Journal: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20070101

Title: Oxidation of glutathione and superoxide generation by inorganic and organic selenium compounds.

Journal: BioFactors (Oxford, England) 20070101

Title: ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20061212

Title: Tethered lipid bilayers on electrolessly deposited gold for bioelectronic applications.

Journal: Biomacromolecules 20061201

Title: Therapeutic Strategies in Huntington's Disease.

Journal: Journal of clinical neurology (Seoul, Korea) 20061201

Title: Tissue transglutaminase crosslinks ataxin-1: possible role in SCA1 pathogenesis.

Journal: Neuroscience letters 20061127

Title: Hyperhomocysteinemia and low plasma folate as risk factors for central retinal vein occlusion: a case-control study in a Chinese population.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20061001

Title: Leishmania species: evidence for transglutaminase activity and its role in parasite proliferation.

Journal: Experimental parasitology 20061001

Title: Complex formation between tissue transglutaminase II (tTG) and vascular endothelial growth factor receptor 2 (VEGFR-2): proposed mechanism for modulation of endothelial cell response to VEGF.

Journal: Experimental cell research 20061001

Title: A rapid transglutaminase assay for high-throughput screening applications.

Journal: Journal of biomolecular screening 20061001

Title: Colorimetric multiplexed immunoassay using specific aggregation of antigenic peptide-modified luminous nanoparticles.

Journal: Analytica chimica acta 20060918

Title: Capillary electrophoresis method development for determination of impurities in sodium cysteamine phosphate samples.

Journal: Journal of pharmaceutical and biomedical analysis 20060911

Title: Biodegradable cystamine spacer facilitates the clearance of Gd(III) chelates in poly(glutamic acid) Gd-DO3A conjugates for contrast-enhanced MR imaging.

Journal: Magnetic resonance imaging 20060901

Title: The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase.

Journal: Neurobiology of aging 20060601

Title: Neuroprotective effects of cystamine in aged parkinsonian mice.

Journal: Neurobiology of aging 20060601

Title: Drug shows potential for treatment of Huntington's disease.

Journal: The Lancet. Neurology 20060601

Title: Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.

Journal: The Journal of clinical investigation 20060501

Title: CYTE-I-HD: phase I dose finding and tolerability study of cysteamine (Cystagon) in Huntington's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20060401

Title: Transglutaminase activity regulates osteoblast differentiation and matrix mineralization in MC3T3-E1 osteoblast cultures.

Journal: Matrix biology : journal of the International Society for Matrix Biology 20060401

Title: Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells.

Journal: The European journal of neuroscience 20060401

Title: Stepwise assembly of acceptor--sigma spacer--donor monolayers: preparation and electrochemical characterization.

Journal: Langmuir : the ACS journal of surfaces and colloids 20060328

Title: Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents.

Journal: International journal of nanomedicine 20060301

Title: Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein.

Journal: Biochemistry 20060221

Title: The p53 oncoprotein is a substrate for tissue transglutaminase kinase activity.

Journal: Biochemical and biophysical research communications 20060113

Title: Cysteamine-related agents could be potential antidepressants through increasing central BDNF levels.

Journal: Medical hypotheses 20060101

Title: Phosphoprotein analysis: from proteins to proteomes.

Journal: Proteome science 20060101

Title: Reducible poly(amido ethylenimine)s designed for triggered intracellular gene delivery.

Journal: Bioconjugate chemistry 20060101

Title: Contrast-enhanced magnetic resonance angiography with biodegradable (Gd-DTPA)-cystamine copolymers: comparison with MS-325 in a swine model.

Journal: Molecular pharmaceutics 20060101

Title: [Lorentz Eldjarn--a catalyst for chemistry in Norwegian medicine].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20051215

Title: Identification of an inactivating cysteine switch in protein kinase Cepsilon, a rational target for the design of protein kinase Cepsilon-inhibitory cancer therapeutics.

Journal: Cancer research 20051115

Title: A novel small molecule CFTR inhibitor attenuates HCO3- secretion and duodenal ulcer formation in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20051001

Title: Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

Journal: Journal of neurochemistry 20051001

Title: Covalent attachment of glucose oxidase to an Au electrode modified with gold nanoparticles for use as glucose biosensor.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20050901

Title: Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease.

Journal: Journal of neurochemistry 20050801

Title: A general fluorescence-based coupled assay for S-adenosylmethionine-dependent methyltransferases.

Journal: Biochemical and biophysical research communications 20050527

Title: Construction of a tethered poly(ethylene glycol) surface gradient for studies of cell adhesion kinetics.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050524

Title: Determination of total cysteamine in human plasma in the form of its 2-S-quinolinium derivative by high performance liquid chromatography.

Journal: Analytical and bioanalytical chemistry 20050501

Title: Post-translational disulfide modifications in cell signaling--role of inter-protein, intra-protein, S-glutathionyl, and S-cysteaminyl disulfide modifications in signal transmission.

Journal: Free radical research 20050501

Title: Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease.

Journal: Journal of the neurological sciences 20050415

Title: Pharmacokinetics and tissue retention of (Gd-DTPA)-cystamine copolymers, a biodegradable macromolecular magnetic resonance imaging contrast agent.

Journal: Pharmaceutical research 20050401

Title: Glutathione synthesis in Streptococcus agalactiae. One protein accounts for gamma-glutamylcysteine synthetase and glutathione synthetase activities.

Journal: The Journal of biological chemistry 20050325

Title: Mechanism for the inhibition of transglutaminase 2 by cystamine.

Journal: Biochemical pharmacology 20050315

Title: Resistance of zwitterionic telomers accumulated on metal surfaces against nonspecific adsorption of proteins.

Journal: Journal of colloid and interface science 20050215

Title: Characterization of purified rat testicular transglutaminase and age-dependent changes of the enzyme activities.

Journal: The international journal of biochemistry & cell biology 20050201

Title: Small artery remodeling depends on tissue-type transglutaminase.

Journal: Circulation research 20050107

Title: Formulation and surface modification of poly(ester-anhydride) micro- and nanospheres.

Journal: Biomaterials 20050101

Title: Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.

Journal: Journal of neuropathology and experimental neurology 20050101

Title: Poly(ethylene oxide)-b-poly(N-isopropylacrylamide) nanoparticles with cross-linked cores as drug carriers.

Journal: Journal of biomaterials science. Polymer edition 20050101

Title: The influence of methylene blue on the spontaneous contractity of the non-pregnant human myometrium and on the myometrial response to DEA/NO.

Journal: Cellular & molecular biology letters 20050101

Title: Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine.

Journal: Experimental & molecular medicine 20041231

Title: Interrelationships among microbiological, physicochemical, and biochemical properties of Terrincho cheese, with emphasis on biogenic amines.

Journal: Journal of food protection 20041201

Title: Isolation and functional characterization of a cyst(e)amine-sensitive protein protecting methyl-dithio groups.

Journal: Biochimie 20041201

Title: Fishing of beta-amylase with a SAM of alpha-cyclodextrin-poly- (ethylene glycol) conjugate.

Journal: Journal of colloid and interface science 20041115

Title: Cell-based assay for monitoring transglutaminase activity.

Journal: Analytical biochemistry 20041015

Title: Production of dromedary (Camelus dromedarius) embryos by IVM and IVF and co-culture with oviductal or granulosa cells.

Journal: Theriogenology 20041001

Title: Amperometric cholesterol biosensor based on in situ reconstituted cholesterol oxidase on an immobilized monolayer of flavin adenine dinucleotide cofactor.

Journal: Analytical biochemistry 20041001

Title: Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.

Journal: Journal of neurochemistry 20041001

Title: Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.

Journal: The Journal of biological chemistry 20040806

Title: Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress.

Journal: Molecular and cellular biology 20040801

Title: Dependence of Giardia lamblia encystation on novel transglutaminase activity.

Journal: Molecular and biochemical parasitology 20040801

Title: Separation of organoselenium compounds and their electrochemical detection.

Journal: Analytical and bioanalytical chemistry 20040701

Title: Synthesis, structure and electrochemistry of ferrocene-peptide macrocycles.

Journal: Dalton transactions (Cambridge, England : 2003) 20040607

Title: A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome.

Journal: The Journal of biological chemistry 20040604

Title: Tissue transglutaminase has intrinsic kinase activity: identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase.

Journal: The Journal of biological chemistry 20040604

Title: Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells.

Journal: Life sciences 20040604

Title: Piezoelectric biosensors for real-time monitoring of hybridization and detection of hepatitis C virus.

Journal: Journal of virological methods 20040501

Title: Accumulation of phenyl boronic acid-carrying telomers on a gold surface.

Journal: Journal of colloid and interface science 20040501

Title: The immunosensors for measurement of 2,4-dichlorophenoxyacetic acid based on electrochemical impedance spectroscopy.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040401

Title: Transglutaminases - possible drug targets in human diseases.

Journal: Current drug targets. CNS and neurological disorders 20040401

Title: Protective role of tissue transglutaminase in the cell death induced by TNF-alpha in SH-SY5Y neuroblastoma cells.

Journal: Journal of biochemistry and molecular biology 20040331

Title: Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores.

Journal: The Journal of clinical investigation 20040215

Title: Pigment-lightening effect of N,N'-dilinoleylcystamine on human melanoma cells.

Journal: The British journal of dermatology 20040101

Title: Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice.

Journal: BMC neuroscience 20040101

Title: Radioprotective effects of amifostine (WR-2721) or cystamine on radiation damage and its repair in rats whole body exposed to fission neutrons.

Journal: Acta medica (Hradec Kralove) 20040101

Title: Induction of the mitochondrial permeability transition by selenium compounds mediated by oxidation of the protein thiol groups and generation of the superoxide.

Journal: Biochemical pharmacology 20031215

Title: Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route.

Journal: British journal of clinical pharmacology 20031201

Title: Cystamine inhibits transglutaminase and caspase-3 cleavage in glutamate-exposed astroglial cells.

Journal: Journal of neuroscience research 20031001

Title: Effects of monoamines formed in the cecum of horses on equine digital blood vessels and platelets.

Journal: American journal of veterinary research 20030901

Title: Identifying and modulating disulfide formation in the biopharmaceutical production of a recombinant protein vaccine candidate.

Journal: Journal of biotechnology 20030815

Title: Transglutaminase potentiates ligand-dependent proteasome dysfunction induced by polyglutamine-expanded androgen receptor.

Journal: Human molecular genetics 20030701

Title: Activation of in situ tissue transglutaminase by intracellular reactive oxygen species.

Journal: Biochemical and biophysical research communications 20030606

Title: Contact allergy to cystamine bis-lactamide.

Journal: Contact dermatitis 20030601

Title: Synthesis and antifilarial evaluation of N1,Nn- xylofuranosylated diaminoalkanes.

Journal: Bioorganic & medicinal chemistry 20030417

Title: Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders.

Journal: The Journal of biological chemistry 20030207

Title: Surface modification of poly(lactic acid) nanoparticles by covalent attachment of thiol groups by means of three methods.

Journal: International journal of pharmaceutics 20030116

Title: [Comparative study of radioprotective efficiency of various doses of cystamine dissolved in normal saline solution or distilled water].

Journal: Radiatsionnaia biologiia, radioecologiia 20030101

Title: Enhancement of the depigmenting effect of hydroquinone and 4-hydroxyanisole by all-trans-retinoic acid (tretinoin): the impairment of glutathione-dependent cytoprotection?

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Poly(l-glutamic acid) Gd(III)-DOTA conjugate with a degradable spacer for magnetic resonance imaging.

Journal: Bioconjugate chemistry 20030101

Title: In vitro proteoglycan sulfation derived from sulfhydryl compounds in sulfate transporter chondrodysplasias.

Journal: Pediatric pathology & molecular medicine 20030101

Title: Ferrocenoyl glycylcystamine: organization into a supramolecular helicate structure.

Journal: Chemical communications (Cambridge, England) 20021021

Title: Therapeutic effects of cystamine in a murine model of Huntington's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021015

Title: Direct calcium binding results in activation of brain serine racemase.

Journal: The Journal of biological chemistry 20020802

Title: High-performance liquid chromatographic method to quantify total cysteine excretion in urine.

Journal: Analytical biochemistry 20020801

Title: Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.

Journal: Analytical and bioanalytical chemistry 20020701

Title: Determination of alpha-fetoprotein in human serum by a quartz crystal microbalance-based immunosensor.

Journal: Clinical chemistry 20020601

Title: Transglutaminase activity of human ER-60.

Journal: Bioscience, biotechnology, and biochemistry 20020601

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SDS
Tags:51-85-4 Molecular Formula|51-85-4 MDL|51-85-4 SMILES|51-85-4 2,2'-Disulfanediyldiethanamine
Catalog No.: AA00DVMV
51-85-4,MFCD01002952
51-85-4 | 2,2'-Disulfanediyldiethanamine
Pack Size: 1g
Purity: 95%
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$130.00 $91.00
Pack Size: 5g
Purity: 95%
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$412.00 $289.00
Pack Size: 10g
Purity: 96%
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$774.00 $542.00
Pack Size: 25g
Purity: 95%
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Technical Information
Catalog Number: AA00DVMV
Chemical Name: 2,2'-Disulfanediyldiethanamine
CAS Number: 51-85-4
Molecular Formula: C4H12N2S2
Molecular Weight: 152.2815
MDL Number: MFCD01002952
SMILES: NCCSSCCN
Properties
BP: 106-108 °C(Press: 5 Torr)  
Form: Liquid  
MP: 135-136 °C  
Refractive Index: 1.5605 (estimate)  
Storage: Room Temperature;Light sensitive;Inert atmosphere;  
Complexity: 37  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 8  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1  
Downstream Synthesis Route
56-89-3    51-85-4 

[1]ChemischesZentralblatt,1907,vol.78,p.1156

51-85-4    4403-36-5    63277-01-0 

[1]JournaloftheChemicalSociety,1954,p.1171,1176

109653-49-8    51-85-4 

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-DE1000391,1957,BViscontinietal.[HelveticaChimicaActa,1953,vol.36,p.835]

[2]Schoeberl[Hoppe-Seyler'sZeitschriftfurPhysiologischeChemie,1933,vol.216,p.196]

[3]CurrentPatentAssignee:ROCHEHOLDINGAG-DE1000391,1957,BViscontinietal.[HelveticaChimicaActa,1953,vol.36,p.835]

60-23-1    51-85-4 

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51-85-4    583-47-1   
2-Amino-N-2-(2-amino-ethyldisulfanyl)-ethyl-3-phenyl-propionamide 

[1]BulletinoftheAcademyofSciencesoftheUSSRDivisionofChemicalScience,1967,p.317-323    IzvestiyaAkademiiNaukSSSR,SeriyaKhimicheskaya,1967,p.334-341

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Title: Potential of transglutaminase 2 as a therapeutic target.

Journal: Expert opinion on therapeutic targets20100901

Title: Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.

Journal: Nature cell biology20100901

Title: The role of mitochondria in brain aging and the effects of melatonin.

Journal: Current neuropharmacology20100901

Title: I-kappaBalpha depletion by transglutaminase 2 and mu-calpain occurs in parallel with the ubiquitin-proteasome pathway.

Journal: Biochemical and biophysical research communications20100820

Title: Tailorable thiolated trimethyl chitosans for covalently stabilized nanoparticles.

Journal: Biomacromolecules20100809

Title: Garlic extract prevents CCl(4)-induced liver fibrosis in rats: The role of tissue transglutaminase.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver20100801

Title: Serotonin--more than a neurotransmitter: transglutaminase-mediated serotonylation of C6 glioma cells and fibronectin.

Journal: Neurochemistry international20100801

Title: Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine-hyaluronic acid conjugate.

Journal: Biomaterials20100701

Title: Stability and biodistribution of a biodegradable macromolecular MRI contrast agent Gd-DTPA cystamine copolymers (GDCC) in rats.

Journal: Pharmaceutical research20100701

Title: Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription.

Journal: Experimental neurology20100701

Title: An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation. 1985.

Journal: British journal of pharmacology20100701

Title: Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice.

Journal: Brain research20100604

Title: Cystamine suppresses polyalanine toxicity in a mouse model of oculopharyngeal muscular dystrophy.

Journal: Science translational medicine20100602

Title: Transglutaminase participates in the blockade of neurotransmitter release by tetanus toxin: evidence for a novel biological function.

Journal: Amino acids20100601

Title: A profiling platform for the characterization of transglutaminase 2 (TG2) inhibitors.

Journal: Journal of biomolecular screening20100601

Title: Proteomic analysis for the anti-apoptotic effects of cystamine on apoptosis-prone macrophage.

Journal: Journal of cellular biochemistry20100601

Title: Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: chemical strategies to prepare glycoconjugates with good carbohydrate loading.

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Title: Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents.

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Title: Facile fabrication of uniform silica films with tunable physical properties using silicatein protein from sponges.

Journal: Langmuir : the ACS journal of surfaces and colloids20100316

Title: An in situ and in vitro investigation for the transglutaminase potential in tissue engineering.

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Title: Reducible poly(amido ethylenimine)-based gene delivery system for improved nucleus trafficking of plasmid DNA.

Journal: Bioconjugate chemistry20100217

Title: Impaired clot retraction in factor XIII A subunit-deficient mice.

Journal: Blood20100211

Title: Cystamine prevents MPTP-induced toxicity in young adult mice via the up-regulation of the brain-derived neurotrophic factor.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20100201

Title: Noninvasive evaluation of antiangiogenic effect in a mouse tumor model by DCE-MRI with Gd-DTPA cystamine copolymers.

Journal: Molecular pharmaceutics20100201

Title: Transglutaminase II interacts with rac1, regulates production of reactive oxygen species, expression of snail, secretion of Th2 cytokines and mediates in vitro and in vivo allergic inflammation.

Journal: Molecular immunology20100201

Title: A novel therapeutic target in inflammatory uveitis: transglutaminase 2 inhibitor.

Journal: Korean journal of ophthalmology : KJO20100201

Title: Transglutaminase 2 expression levels regulate sensitivity to cystamine plus TRAIL-mediated apoptosis.

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Title: Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin.

Journal: Brain pathology (Zurich, Switzerland)20100101

Title: Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage.

Journal: BMC molecular biology20100101

Title: Overview of the main methods used to combine proteins with nanosystems: absorption, bioconjugation, and encapsulation.

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Title: Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.

Journal: BMC neuroscience20100101

Title: Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma.

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Title: Synthesis and evaluation of nanoglobule-cystamine-(Gd-DO3A), a biodegradable nanosized magnetic resonance contrast agent for dynamic contrast-enhanced magnetic resonance urography.

Journal: International journal of nanomedicine20100101

Title: Enzymatic strategies to detoxify gluten: implications for celiac disease.

Journal: Enzyme research20100101

Title: Modification of proteins by norepinephrine is important for vascular contraction.

Journal: Frontiers in physiology20100101

Title: Gastric acid hypersecretory states: recent insights and advances.

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Title: A novel array-based assay of in situ tissue transglutaminase activity in human umbilical vein endothelial cells.

Journal: Analytical biochemistry20091115

Title: Modified electrophoretic and digestion conditions allow a simplified mass spectrometric evaluation of disulfide bonds.

Journal: Journal of mass spectrometry : JMS20091101

Title: Selenium functionalized intraocular lenses inhibit posterior capsule opacification in an ex vivo canine lens capsular bag assay.

Journal: Experimental eye research20091101

Title: Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages.

Journal: Bioconjugate chemistry20091101

Title: Sulfur metabolism in AIDS: cystamine as an anti-HIV agent.

Journal: AIDS research and human retroviruses20091101

Title: Biotinylated disulfide containing PEI/avidin bioconjugate shows specific enhanced transfection efficiency in HepG2 cells.

Journal: Organic & biomolecular chemistry20091021

Title: Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20091015

Title: Involvement of tissue transglutaminase in endothelin 1-induced hypertrophy in cultured neonatal rat cardiomyocytes.

Journal: Hypertension (Dallas, Tex. : 1979)20091001

Title: Identification of a novel small molecule HIF-1alpha translation inhibitor.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20091001

Title: Functional delivery of siRNA in mice using dendriworms.

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Title: Identification and quantitation of Bacillus globigii using metal enhanced electrochemical detection and capillary biosensor.

Journal: Analytical chemistry20090915

Title: N-propionyl-cysteaminylphenol-magnetite conjugate (NPrCAP/M) is a nanoparticle for the targeted growth suppression of melanoma cells.

Journal: The Journal of investigative dermatology20090901

Title: Targeting murine heart and brain: visualisation conditions for multi-pinhole SPECT with (99m)Tc- and (123)I-labelled probes.

Journal: European journal of nuclear medicine and molecular imaging20090901

Title: Application of a biodegradable macromolecular contrast agent in dynamic contrast-enhanced MRI for assessing the efficacy of indocyanine green-enhanced photothermal cancer therapy.

Journal: Journal of magnetic resonance imaging : JMRI20090801

Title: Polyhydroxylalkyleneamines: a class of hydrophilic cationic polymer-based gene transfer agents.

Journal: Journal of controlled release : official journal of the Controlled Release Society20090701

Title: Folate deficiency induces neural stem cell apoptosis by increasing homocysteine in vitro.

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Title: Synthesis and characterization of new ferrocene peptide conjugates.

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Title: Disulfide-crosslinked electrospun poly(gamma-glutamic acid) nonwovens as reduction-responsive scaffolds.

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Title: Biological and magnetic contrast evaluation of shape-selective Mn-Fe nanowires.

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Title: Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1.

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Title: Structure of pig heart citrate synthase at 1.78 A resolution.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications20090501

Title: PMMA biosensor for nucleic acids with integrated mixer and electrochemical detection.

Journal: Biosensors & bioelectronics20090415

Title: Surface IR applied to rapid and direct immunosensing of environmental pollutants.

Journal: Talanta20090415

Title: Homocysteine-induced toxicity increases TG2 expression in Neuro2a cells.

Journal: Amino acids20090401

Title: Cystamine attenuates the expressions of NOS- and TLR-associated molecules in the brain of NZB/W F1 mice.

Journal: European journal of pharmacology20090401

Title: Expression of tissue-type transglutaminase (tTG) and the effect of tTG inhibitor on the hippocampal CA1 region after transient ischemia in gerbils.

Journal: Brain research20090331

Title: Myenteric neuronal loss in rats with experimental colitis: role of tissue transglutaminase-induced apoptosis.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver20090301

Title: Oxidation of Cys278 of ADH I isozyme from Kluyveromyces lactis by naturally occurring disulfides causes its reversible inactivation.

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Title: Optical properties and application of a reactive and bioreducible thiol-containing tetramethylrhodamine dimer.

Journal: Bioconjugate chemistry20090301

Title: Depletion of nucleophosmin via transglutaminase 2 cross-linking increases drug resistance in cancer cells.

Journal: Cancer letters20090218

Title: Degradable nanogels as a nanoreactor for growing silica colloids.

Journal: Langmuir : the ACS journal of surfaces and colloids20090217

Title: Glucosamine is an effective chemo-sensitizer via transglutaminase 2 inhibition.

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Title: Tissue-type transglutaminase and the effects of cystamine on intracerebral hemorrhage-induced brain edema and neurological deficits.

Journal: Brain research20090116

Title: Increased expression of Matrix Metalloproteinase 9 in liver from NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein.

Journal: Journal of biomedical science20090101

Title: Silencing of TGase 2 sensitizes breast cancer cells to apoptosis by regulation of survival factors.

Journal: Frontiers in bioscience (Landmark edition)20090101

Title: Calculating CVD risk in older patients.

Journal: The Practitioner20090101

Title: Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties.

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Title: Plasma homocysteine is adversely associated with glomerular filtration rate in asymptomatic black and white young adults: the Bogalusa heart study.

Journal: European journal of epidemiology20090101

Title: Serotonylation of vascular proteins important to contraction.

Journal: PloS one20090101

Title: Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy.

Journal: Journal of biomedicine & biotechnology20090101

Title: Doxorubicin loaded Polymeric Nanoparticulate Delivery System to overcome drug resistance in osteosarcoma.

Journal: BMC cancer20090101

Title: Advances and prospect of nanotechnology in stem cells.

Journal: Nanoscale research letters20090101

Title: A novel piezoelectric quartz crystal immnuosensor based on hyperbranched polymer films for the detection of alpha-Fetoprotein.

Journal: Analytica chimica acta20081207

Title: Enhancement of electrochemical signal on gold electrodes by polyvalent esterase-dendrimer clusters.

Journal: Bioconjugate chemistry20081201

Title: Tunable redox-responsive hybrid nanogated ensembles.

Journal: Journal of the American Chemical Society20081105

Title: Cystamine prevents haloperidol-induced decrease of BDNF/TrkB signaling in mouse frontal cortex.

Journal: Journal of neurochemistry20081101

Title: The role of physical activity level and B-vitamin status on blood homocysteine levels.

Journal: Medicine and science in sports and exercise20081101

Title: ATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.

Journal: The FEBS journal20081101

Title: A new synthesis of cystamine modified Eu3+ DOTAM-Gly-Phe-OH: a conjugation ready temperature sensitive MRI contrast agent.

Journal: Organic & biomolecular chemistry20081007

Title: Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles.

Journal: Biomacromolecules20081001

Title: Highly sensitive electrochemical detection of immunospecies based on combination of Fc label and PPD film/gold nanoparticle amplification.

Journal: Biosensors & bioelectronics20080915

Title: Beneficial effects of treatment with cystamine on brain in NZB/W F1 mice.

Journal: European journal of pharmacology20080904

Title: Drastically decreased reactivity of thiols and disulfides complexed by cucurbit[6]uril.

Journal: Organic letters20080904

Title: Characterization of mixed self-assembled monolayers for immobilization of streptavidin using chemical force microscopy.

Journal: Ultramicroscopy20080901

Title: The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure.

Journal: PLoS pathogens20080901

Title: Method for determination of total cysteamine in human plasma by high performance capillary electrophoresis with acetonitrile stacking.

Journal: Electrophoresis20080901

Title: Sensitivity enhancement by Au nanoparticles in surface plasmon resonance chemical sensors.

Journal: Journal of nanoscience and nanotechnology20080901

Title: Novel poly(amido amine)s with bioreducible disulfide linkages in their diamino-units: structure effects and in vitro gene transfer properties.

Journal: Journal of controlled release : official journal of the Controlled Release Society20080825

Title: Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry20080801

Title: Vasoconstrictor effect of aldosterone via angiotensin II type 1 (AT1) receptor: possible role of AT1 receptor dimerization.

Journal: Cardiovascular research20080701

Title: Transglutaminase-catalyzed transamidation: a novel mechanism for Rac1 activation by 5-hydroxytryptamine2A receptor stimulation.

Journal: The Journal of pharmacology and experimental therapeutics20080701

Title: Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes.

Journal: Diabetologia20080701

Title: EPR characterization of gadolinium(III)-containing-PAMAM-dendrimers in the absence and in the presence of paramagnetic probes.

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Title: The effect of guanylate cyclase inhibitors on non-adrenergic and non-cholinergic neurogenic relaxations of the South American opossum lower esophageal sphincter.

Journal: Fundamental & clinical pharmacology20080601

Title: Synthesis and swelling properties of novel pH-sensitive poly(aspartic acid) gels.

Journal: Acta biomaterialia20080501

Title: Toxins from cone snails: properties, applications and biotechnological production.

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Title: Transglutaminase 2 and NF-kappaB interplay during NGF-induced differentiation of neuroblastoma cells.

Journal: Brain research20080501

Title: Disulfide S-monoxides convert xanthine dehydrogenase into oxidase in rat liver cytosol more potently than their respective disulfides.

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Title: Pulse radiolysis studies on reactions of hydroxyl radicals with selenocystine derivatives.

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Title: Malondialdehyde, a lipid-derived aldehyde alters the reactivity of Cys34 and the esterase activity of serum albumin.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20080401

Title: No association between global leukocyte DNA methylation and homocysteine levels in schizophrenia patients.

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Title: Treatment with cystamine reduces apoptosis in liver from NZB/W F1 mice.

Journal: International immunopharmacology20080401

Title: Cystamine restores GSTA3 levels in Vanin-1 null mice.

Journal: Free radical biology & medicine20080315

Title: Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease.

Journal: Biochimica et biophysica acta20080301

Title: A label-free biosensor based on gold nanoshell monolayers for monitoring biomolecular interactions in diluted whole blood.

Journal: Biosensors & bioelectronics20080227

Title: Transglutaminase inhibitor cystamine alleviates the abnormality in liver from NZB/W F1 mice.

Journal: European journal of pharmacology20080128

Title: Cystamine prevents ischemia-reperfusion injury by inhibiting polyamination of RhoA.

Journal: Biochemical and biophysical research communications20080118

Title: Hyaluronic acid induces transglutaminase II to enhance cell motility; role of Rac1 and FAK in the induction of transglutaminase II.

Journal: Biotechnology letters20080101

Title: Structure and function of A41, a vaccinia virus chemokine binding protein.

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Journal: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine20080101

Title: Effect of disulfide-containing compounds on the Na+ transport in the frog skin.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections20080101

Title: Resolution of complex fluorescence spectra of lipids and nicotinic acetylcholine receptor by multivariate analysis reveals protein-mediated effects on the receptor's immediate lipid microenvironment.

Journal: PMC biophysics20080101

Title: The physiological role of the Gomori-positive glia: a new hypothesis.

Journal: Folia medica Cracoviensia20080101

Title: Nickel-cysteine binding supported by phosphine chelates.

Journal: Inorganic chemistry20071029

Title: ATP-mediated mineralization of MC3T3-E1 osteoblast cultures.

Journal: Bone20071001

Title: Studies on the reducing systems for plant and animal thioredoxin-independent methionine sulfoxide reductases B.

Journal: Biochemical and biophysical research communications20070928

Title: Ultrasensitive detection of enzymatic activity with nanowire electrodes.

Journal: Journal of the American Chemical Society20070919

Title: [Long-term follow-up of ofloxacin-combined therapy for leprosy patients].

Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association20070901

Title: Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase.

Journal: World journal of gastroenterology20070828

Title: Thiolato-bridged RuIIAgIRuII trinuclear complex composed of bis(bipyridine)ruthenium(II) units with chelating 2-aminoethanethiolate: conversion to a disulfide-bridged RuIIRuII dinuclear complex.

Journal: Inorganic chemistry20070820

Title: Facile synthetic procedure for omega, primary amine functionalization directly in water for subsequent fluorescent labeling and potential bioconjugation of RAFT-synthesized (co)polymers.

Journal: Biomacromolecules20070801

Title: Cellular thiol pools are responsible for sequestration of cytotoxic reactive aldehydes: central role of free cysteine and cysteamine.

Journal: Brain research20070716

Title: Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.

Journal: Toxicology and applied pharmacology20070715

Title: Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1.

Journal: Neuroscience letters20070608

Title: The construction of 3D-engineered tissues composed of cells and extracellular matrices by hydrogel template approach.

Journal: Biomaterials20070601

Title: RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker alpha(v) beta3 integrin with MRT, mapping.

Journal: International journal of nanomedicine20070601

Title: Proteomic analysis of high-molecular-weight protein polymers in a doxorubicin-resistant breast-cancer cell line.

Journal: Proteomics. Clinical applications20070601

Title: Stable supply of large amounts of human Fab from the inclusion bodies in E. coli.

Journal: Journal of biochemistry20070501

Title: Surface studies of aminoferrocene derivatives on gold: electrochemical sensors for chemical warfare agents.

Journal: Analytical chemistry20070401

Title: PbnI4n+2(2n+2)- ribbons (n = 3, 5) as dimensional reductions of 2D perovskite layers in cystamine cation based hybrids, also incorporating iodine molecules or reversible guest water molecules.

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Title: Osteopontin promotes pathologic mineralization in articular cartilage.

Journal: Matrix biology : journal of the International Society for Matrix Biology20070301

Title: Differential tumor cell targeting of anti-HER2 (Herceptin) and anti-CD20 (Mabthera) coupled nanoparticles.

Journal: International journal of pharmaceutics20070301

Title: Diagnosis of tularemia using piezoelectric biosensor technology.

Journal: Talanta20070215

Title: Beneficial effects of treatment with transglutaminase inhibitor cystamine on macrophage response in NZB/W F1 mice.

Journal: Experimental biology and medicine (Maywood, N.J.)20070201

Title: Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor.

Journal: European journal of immunology20070201

Title: Methylenetetrahydrofolate reductase gene polymorphism and its association with coronary artery disease.

Journal: Sao Paulo medical journal = Revista paulista de medicina20070104

Title: Diphenic acid as a general conformational lock in the design of bihelical structures.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20070101

Title: Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans.

Journal: PloS one20070101

Title: Chronic cystamine treatment inhibits small artery remodelling in rats.

Journal: Journal of vascular research20070101

Title: [Comparative protective action of radiorotectors and shielding in gamma-irradiated mice].

Journal: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine20070101

Title: Oxidation of glutathione and superoxide generation by inorganic and organic selenium compounds.

Journal: BioFactors (Oxford, England)20070101

Title: ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America20061212

Title: Tethered lipid bilayers on electrolessly deposited gold for bioelectronic applications.

Journal: Biomacromolecules20061201

Title: Therapeutic Strategies in Huntington's Disease.

Journal: Journal of clinical neurology (Seoul, Korea)20061201

Title: Tissue transglutaminase crosslinks ataxin-1: possible role in SCA1 pathogenesis.

Journal: Neuroscience letters20061127

Title: Hyperhomocysteinemia and low plasma folate as risk factors for central retinal vein occlusion: a case-control study in a Chinese population.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie20061001

Title: Leishmania species: evidence for transglutaminase activity and its role in parasite proliferation.

Journal: Experimental parasitology20061001

Title: Complex formation between tissue transglutaminase II (tTG) and vascular endothelial growth factor receptor 2 (VEGFR-2): proposed mechanism for modulation of endothelial cell response to VEGF.

Journal: Experimental cell research20061001

Title: A rapid transglutaminase assay for high-throughput screening applications.

Journal: Journal of biomolecular screening20061001

Title: Colorimetric multiplexed immunoassay using specific aggregation of antigenic peptide-modified luminous nanoparticles.

Journal: Analytica chimica acta20060918

Title: Capillary electrophoresis method development for determination of impurities in sodium cysteamine phosphate samples.

Journal: Journal of pharmaceutical and biomedical analysis20060911

Title: Biodegradable cystamine spacer facilitates the clearance of Gd(III) chelates in poly(glutamic acid) Gd-DO3A conjugates for contrast-enhanced MR imaging.

Journal: Magnetic resonance imaging20060901

Title: The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase.

Journal: Neurobiology of aging20060601

Title: Neuroprotective effects of cystamine in aged parkinsonian mice.

Journal: Neurobiology of aging20060601

Title: Drug shows potential for treatment of Huntington's disease.

Journal: The Lancet. Neurology20060601

Title: Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.

Journal: The Journal of clinical investigation20060501

Title: CYTE-I-HD: phase I dose finding and tolerability study of cysteamine (Cystagon) in Huntington's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society20060401

Title: Transglutaminase activity regulates osteoblast differentiation and matrix mineralization in MC3T3-E1 osteoblast cultures.

Journal: Matrix biology : journal of the International Society for Matrix Biology20060401

Title: Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells.

Journal: The European journal of neuroscience20060401

Title: Stepwise assembly of acceptor--sigma spacer--donor monolayers: preparation and electrochemical characterization.

Journal: Langmuir : the ACS journal of surfaces and colloids20060328

Title: Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents.

Journal: International journal of nanomedicine20060301

Title: Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein.

Journal: Biochemistry20060221

Title: The p53 oncoprotein is a substrate for tissue transglutaminase kinase activity.

Journal: Biochemical and biophysical research communications20060113

Title: Cysteamine-related agents could be potential antidepressants through increasing central BDNF levels.

Journal: Medical hypotheses20060101

Title: Phosphoprotein analysis: from proteins to proteomes.

Journal: Proteome science20060101

Title: Reducible poly(amido ethylenimine)s designed for triggered intracellular gene delivery.

Journal: Bioconjugate chemistry20060101

Title: Contrast-enhanced magnetic resonance angiography with biodegradable (Gd-DTPA)-cystamine copolymers: comparison with MS-325 in a swine model.

Journal: Molecular pharmaceutics20060101

Title: [Lorentz Eldjarn--a catalyst for chemistry in Norwegian medicine].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke20051215

Title: Identification of an inactivating cysteine switch in protein kinase Cepsilon, a rational target for the design of protein kinase Cepsilon-inhibitory cancer therapeutics.

Journal: Cancer research20051115

Title: A novel small molecule CFTR inhibitor attenuates HCO3- secretion and duodenal ulcer formation in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology20051001

Title: Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

Journal: Journal of neurochemistry20051001

Title: Covalent attachment of glucose oxidase to an Au electrode modified with gold nanoparticles for use as glucose biosensor.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20050901

Title: Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.

Journal: The Journal of pharmacology and experimental therapeutics20050801

Title: Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease.

Journal: Journal of neurochemistry20050801

Title: A general fluorescence-based coupled assay for S-adenosylmethionine-dependent methyltransferases.

Journal: Biochemical and biophysical research communications20050527

Title: Construction of a tethered poly(ethylene glycol) surface gradient for studies of cell adhesion kinetics.

Journal: Langmuir : the ACS journal of surfaces and colloids20050524

Title: Determination of total cysteamine in human plasma in the form of its 2-S-quinolinium derivative by high performance liquid chromatography.

Journal: Analytical and bioanalytical chemistry20050501

Title: Post-translational disulfide modifications in cell signaling--role of inter-protein, intra-protein, S-glutathionyl, and S-cysteaminyl disulfide modifications in signal transmission.

Journal: Free radical research20050501

Title: Cerebral PET imaging and histological evidence of transglutaminase inhibitor cystamine induced neuroprotection in transgenic R6/2 mouse model of Huntington's disease.

Journal: Journal of the neurological sciences20050415

Title: Pharmacokinetics and tissue retention of (Gd-DTPA)-cystamine copolymers, a biodegradable macromolecular magnetic resonance imaging contrast agent.

Journal: Pharmaceutical research20050401

Title: Glutathione synthesis in Streptococcus agalactiae. One protein accounts for gamma-glutamylcysteine synthetase and glutathione synthetase activities.

Journal: The Journal of biological chemistry20050325

Title: Mechanism for the inhibition of transglutaminase 2 by cystamine.

Journal: Biochemical pharmacology20050315

Title: Resistance of zwitterionic telomers accumulated on metal surfaces against nonspecific adsorption of proteins.

Journal: Journal of colloid and interface science20050215

Title: Characterization of purified rat testicular transglutaminase and age-dependent changes of the enzyme activities.

Journal: The international journal of biochemistry & cell biology20050201

Title: Small artery remodeling depends on tissue-type transglutaminase.

Journal: Circulation research20050107

Title: Formulation and surface modification of poly(ester-anhydride) micro- and nanospheres.

Journal: Biomaterials20050101

Title: Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.

Journal: Journal of neuropathology and experimental neurology20050101

Title: Poly(ethylene oxide)-b-poly(N-isopropylacrylamide) nanoparticles with cross-linked cores as drug carriers.

Journal: Journal of biomaterials science. Polymer edition20050101

Title: The influence of methylene blue on the spontaneous contractity of the non-pregnant human myometrium and on the myometrial response to DEA/NO.

Journal: Cellular & molecular biology letters20050101

Title: Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine.

Journal: Experimental & molecular medicine20041231

Title: Interrelationships among microbiological, physicochemical, and biochemical properties of Terrincho cheese, with emphasis on biogenic amines.

Journal: Journal of food protection20041201

Title: Isolation and functional characterization of a cyst(e)amine-sensitive protein protecting methyl-dithio groups.

Journal: Biochimie20041201

Title: Fishing of beta-amylase with a SAM of alpha-cyclodextrin-poly- (ethylene glycol) conjugate.

Journal: Journal of colloid and interface science20041115

Title: Cell-based assay for monitoring transglutaminase activity.

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Title: Production of dromedary (Camelus dromedarius) embryos by IVM and IVF and co-culture with oviductal or granulosa cells.

Journal: Theriogenology20041001

Title: Amperometric cholesterol biosensor based on in situ reconstituted cholesterol oxidase on an immobilized monolayer of flavin adenine dinucleotide cofactor.

Journal: Analytical biochemistry20041001

Title: Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.

Journal: Journal of neurochemistry20041001

Title: Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.

Journal: The Journal of biological chemistry20040806

Title: Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress.

Journal: Molecular and cellular biology20040801

Title: Dependence of Giardia lamblia encystation on novel transglutaminase activity.

Journal: Molecular and biochemical parasitology20040801

Title: Separation of organoselenium compounds and their electrochemical detection.

Journal: Analytical and bioanalytical chemistry20040701

Title: Synthesis, structure and electrochemistry of ferrocene-peptide macrocycles.

Journal: Dalton transactions (Cambridge, England : 2003)20040607

Title: A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome.

Journal: The Journal of biological chemistry20040604

Title: Tissue transglutaminase has intrinsic kinase activity: identification of transglutaminase 2 as an insulin-like growth factor-binding protein-3 kinase.

Journal: The Journal of biological chemistry20040604

Title: Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells.

Journal: Life sciences20040604

Title: Piezoelectric biosensors for real-time monitoring of hybridization and detection of hepatitis C virus.

Journal: Journal of virological methods20040501

Title: Accumulation of phenyl boronic acid-carrying telomers on a gold surface.

Journal: Journal of colloid and interface science20040501

Title: The immunosensors for measurement of 2,4-dichlorophenoxyacetic acid based on electrochemical impedance spectroscopy.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20040401

Title: Transglutaminases - possible drug targets in human diseases.

Journal: Current drug targets. CNS and neurological disorders20040401

Title: Protective role of tissue transglutaminase in the cell death induced by TNF-alpha in SH-SY5Y neuroblastoma cells.

Journal: Journal of biochemistry and molecular biology20040331

Title: Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores.

Journal: The Journal of clinical investigation20040215

Title: Pigment-lightening effect of N,N'-dilinoleylcystamine on human melanoma cells.

Journal: The British journal of dermatology20040101

Title: Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice.

Journal: BMC neuroscience20040101

Title: Radioprotective effects of amifostine (WR-2721) or cystamine on radiation damage and its repair in rats whole body exposed to fission neutrons.

Journal: Acta medica (Hradec Kralove)20040101

Title: Induction of the mitochondrial permeability transition by selenium compounds mediated by oxidation of the protein thiol groups and generation of the superoxide.

Journal: Biochemical pharmacology20031215

Title: Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route.

Journal: British journal of clinical pharmacology20031201

Title: Cystamine inhibits transglutaminase and caspase-3 cleavage in glutamate-exposed astroglial cells.

Journal: Journal of neuroscience research20031001

Title: Effects of monoamines formed in the cecum of horses on equine digital blood vessels and platelets.

Journal: American journal of veterinary research20030901

Title: Identifying and modulating disulfide formation in the biopharmaceutical production of a recombinant protein vaccine candidate.

Journal: Journal of biotechnology20030815

Title: Transglutaminase potentiates ligand-dependent proteasome dysfunction induced by polyglutamine-expanded androgen receptor.

Journal: Human molecular genetics20030701

Title: Activation of in situ tissue transglutaminase by intracellular reactive oxygen species.

Journal: Biochemical and biophysical research communications20030606

Title: Contact allergy to cystamine bis-lactamide.

Journal: Contact dermatitis20030601

Title: Synthesis and antifilarial evaluation of N1,Nn- xylofuranosylated diaminoalkanes.

Journal: Bioorganic & medicinal chemistry20030417

Title: Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders.

Journal: The Journal of biological chemistry20030207

Title: Surface modification of poly(lactic acid) nanoparticles by covalent attachment of thiol groups by means of three methods.

Journal: International journal of pharmaceutics20030116

Title: [Comparative study of radioprotective efficiency of various doses of cystamine dissolved in normal saline solution or distilled water].

Journal: Radiatsionnaia biologiia, radioecologiia20030101

Title: Enhancement of the depigmenting effect of hydroquinone and 4-hydroxyanisole by all-trans-retinoic acid (tretinoin): the impairment of glutathione-dependent cytoprotection?

Journal: Dermatology (Basel, Switzerland)20030101

Title: Poly(l-glutamic acid) Gd(III)-DOTA conjugate with a degradable spacer for magnetic resonance imaging.

Journal: Bioconjugate chemistry20030101

Title: In vitro proteoglycan sulfation derived from sulfhydryl compounds in sulfate transporter chondrodysplasias.

Journal: Pediatric pathology & molecular medicine20030101

Title: Ferrocenoyl glycylcystamine: organization into a supramolecular helicate structure.

Journal: Chemical communications (Cambridge, England)20021021

Title: Therapeutic effects of cystamine in a murine model of Huntington's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20021015

Title: Direct calcium binding results in activation of brain serine racemase.

Journal: The Journal of biological chemistry20020802

Title: High-performance liquid chromatographic method to quantify total cysteine excretion in urine.

Journal: Analytical biochemistry20020801

Title: Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.

Journal: Analytical and bioanalytical chemistry20020701

Title: Determination of alpha-fetoprotein in human serum by a quartz crystal microbalance-based immunosensor.

Journal: Clinical chemistry20020601

Title: Transglutaminase activity of human ER-60.

Journal: Bioscience, biotechnology, and biochemistry20020601

Title: Discrimination by SZL49 between contractions evoked by noradrenaline in longitudinal and circular muscle of human vas deferens.

Journal: British journal of pharmacology20020501

Title: Transglutaminase activity is involved in Saccharomyces cerevisiae wall construction.

Journal: Microbiology (Reading, England)20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Electron transfer studies on self-assembled monolayers of helical ferrocenoyl-oligoproline-cystamine bound to gold.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry20020415

Title: Modulation of inflammatory paw oedema by cysteamine in the rat.

Journal: Pharmacological research20020401

Title: A piezoelectric immunoassay based on self-assembled monolayers of cystamine and polystyrene sulfonate for determination of Schistosoma japonicum antibodies.

Journal: Analytical and bioanalytical chemistry20020401

Title: Dirofilaria immitis: further characterization of the transglutaminase enzyme and its role in larval molting.

Journal: Parasitology research20020301

Title: Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine.

Journal: Nature medicine20020201

Title: Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form.

Journal: The Journal of biological chemistry20020111

Title: The ability of cystamine to bind DNA.

Journal: Amino acids20020101

Title: [Viability of lyophilized cells of Myxococcus xanthus UKM 10041 and Polyangium cellulosum UKM 10043 in presence of different antioxidants].

Journal: Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993)20020101

Title: Molecular recognition of avidin on biotin-functionalized gold surfaces detected by FT-IRRAS and use of metal carbonyl probes.

Journal: Journal of colloid and interface science20020101

Title: Comparison of different protein immobilization methods on quartz crystal microbalance surface in flow injection immunoassay.

Journal: Analytical biochemistry20011215

Title: The role of tissue transglutaminase in the germinal vesicle breakdown of mouse oocytes.

Journal: Biochemical and biophysical research communications20010817

Title: Catalytic selenols couple the redox cycles of metallothionein and glutathione.

Journal: European journal of biochemistry20010601

Title: T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase.

Journal: European journal of immunology20010501

Title: Palladium-mediated C5 substitution of pyrimidine nucleosides.

Journal: Current protocols in nucleic acid chemistry20010501

Title: Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines.

Journal: The Biochemical journal20010401

Title: Electroanalytical applications of cationic self-assembled monolayers: square-wave voltammetric determination of dopamine and ascorbate.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20010301

Title: Facilitated electrochemical oxidation of NADH and its model compound at gold electrode modified with terminally substituted electroinactive self-assembled monolayers.

Journal: Bioelectrochemistry (Amsterdam, Netherlands)20010301

Title: Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine.

Journal: Medical hypotheses20010301

Title: Analogues of prazosin that bear a benextramine-related polyamine backbone exhibit different antagonism toward alpha1-adrenoreceptor subtypes.

Journal: Journal of medicinal chemistry20010201

Title: Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.

Journal: The Journal of biological chemistry20010112

Title: [Comparative study of the radiation-protective effectiveness of low doses of cysteamine, heparin, and naphtizine in experiments on mice].

Journal: Radiatsionnaia biologiia, radioecologiia20010101

Title: Effects of diallyl disulfide and other donors of sulfane sulfur on the proliferation of human hepatoma cell line (HepG2).

Journal: Neoplasma20010101

Title: Transglutaminase participates in the incorporation of latent TGFbeta into the extracellular matrix of aging articular chondrocytes.

Journal: Connective tissue research20010101

Title: The proteolytic activity and cleavage specificity of fibronectin-gelatinase and fibronectin-lamininase.

Journal: Journal of protein chemistry19990501

Title: Identification of transglutaminase-reactive residues in S100A11.

Journal: The Journal of biological chemistry19980130

Title: Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.

Journal: Journal of medicinal chemistry19970620

Title: In vitro inhibition of the replication of human immunodeficiency virus type 1 by beta-mercaptoethylamine (cysteamine).

Journal: The Journal of infectious diseases19960701

Title: Cystamine inhibits HIV type 1 replication in cells of monocyte/macrophage and T cell lineages.

Journal: AIDS research and human retroviruses19950401

Title: Cystamine potently suppresses in vitro HIV replication in acutely and chronically infected human cells.

Journal: The Journal of clinical investigation19940501

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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