Name: Name:H-Arg(NO2)-OMe HCl
Brand: AABLOCKS
SKU: AA00I943
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00I943

Chemical Name: H-Arg(NO2)-OMe HCl

CAS Number: 51298-62-5

Molecular Formula: C7H16ClN5O4

Molecular Weight: 269.6860

MDL Number: MFCD00039052

SMILES: COC(=O)[C@H](CCCNC(=N)N[N+](=O)[O-])N.Cl

Properties

BP: 383.5°C at 760 mmHg

Form: Solid

MP: 157-161 °C

Refractive Index: 15 ° (C=3, MeOH)

Solubility: H2O: 50 mg/mL

Storage: 2-8℃;

Complexity: 274

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 6

Hydrogen Bond Donor Count: 4

Isotope Atom Count: 0

Rotatable Bond Count: 7

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Literature fold

Title: Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain.

Journal: Journal of medicinal chemistry20111027

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Pfeiffer S, et al. Inhibition of nitric oxide synthesis by NG-nitro-L-arginine methyl ester (L-NAME): requirement forbioactivation to the free acid, NG-nitro-L-arginine. Br J Pharmacol. 1996 Jul;118(6):1433-40.

Title: Kopincová J, et al. L-NAME in the cardiovascular system - nitric oxide synthase activator? Pharmacol Rep. 2012;64(3):511-20.

Title: Lo HC, et al. The Nitric Oxide Synthase Inhibitor NG-Nitro-L-Arginine Methyl Ester Diminishes the Immunomodulatory Effects of Parental Arginine in Rats with Subacute Peritonitis. PLoSOne. 2016 Mar 23;11(3):e0151973.

Title: Luo H, et al. Effect of nitric oxide synthase inhibitor L-NAME on fear extinction in rats: a task-dependent effect. Neurosci Lett. 2014 Jun 20;572:13-8.

Title: Ocsan RJ, et al. Chronic NG-nitro-l-arginine methyl ester (L-NAME) administration in C57BL/6J mice induces a sustained decrease in c-kit positive cells during development of cardiac hypertrophy. J Physiol Pharmacol. 2013 Dec;64(6):727-36.

51298-62-5 | H-Arg(NO2)-OMe HCl