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515-64-0,MFCD00010567
Catalog No.:AA00DEN6

515-64-0 | Sulfisomidine

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Purity
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Price(USD)
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1g
95%
in stock  
$112.00   $78.00
- +
5g
95%
in stock  
$411.00   $288.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DEN6
Chemical Name:
Sulfisomidine
CAS Number:
515-64-0
Molecular Formula:
C12H14N4O2S
Molecular Weight:
278.3302
MDL Number:
MFCD00010567
SMILES:
Nc1ccc(cc1)S(=O)(=O)Nc1cc(C)nc(n1)C
Properties
Computed Properties
 
Complexity:
387  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
1.2  

Downstream Synthesis Route

[1]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1950,vol.70,p.283,284    Chem.Abstr.,1951,p.2894

[1]Patent:CH230864,1938,

[2]Patent:DE967224,1952,

[3]Patent:DE967884,1941,    DRP/DRBPOrg.Chem.,

[4]Patent:CH242053,1943,

[1]Ziegler;Shabica[JournaloftheAmericanChemicalSociety,1954,vol.76,p.594]

[1]CurrentPatentAssignee:NOVARTISAG;BAYERAG;Novartis(w/oSandoz)-US2351333,1941,ACurrentPatentAssignee:NOVARTISAG;BAYERAG;Novartis(w/oSandoz)-CH220347,1940,A

[2]CurrentPatentAssignee:NOVARTISAG;CIBAPHARMACEUTICALPRODUCTS,INC.;Novartis(w/oSandoz)-US2429184,1943,ACurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-CH231194,1938,A

[3]CurrentPatentAssignee:Novartis(w/oSandoz);STEINDCHIMBALE;NOVARTISAG-CH242053,1943,A

[1]CurrentPatentAssignee:NOVARTISAG;CIBAPHARMACEUTICALPRODUCTS,INC.;Novartis(w/oSandoz)-US2429184,1943,ALoop;Luehrs[JustusLiebigsAnnalenderChemie,1953,vol.580,p.225,233]

[2]CurrentPatentAssignee:NOVARTISAG;CIBAPHARMACEUTICALPRODUCTS,INC.;Novartis(w/oSandoz)-US2429184,1943,A

Literature

Title: Assessment of the inhibitory effects and molecular docking of some sulfonamides on human serum paraoxonase 1.

Journal: Journal of biochemical and molecular toxicology 20171001

Title: Identification of isobaric amino-sulfonamides without prior separation.

Journal: Rapid communications in mass spectrometry : RCM 20120227

Title: Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110901

Title: Extended hildebrand solubility approach: satranidazole in mixtures of dioxane and water.

Journal: Indian journal of pharmaceutical sciences 20110101

Title: In-vitro antifungal activities of sulfa drugs against clinical isolates of Aspergillus and Cryptococcus species.

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20070101

Title: Identification of the 'wrong' active pharmaceutical ingredient in a counterfeit Halfan drug product using accurate mass electrospray ionisation mass spectrometry, accurate mass tandem mass spectrometry and liquid chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: [Drugs and breastfeeding].

Journal: Medycyna wieku rozwojowego 20020101

Title: Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs.

Journal: Antimicrobial agents and chemotherapy 19950801

Title: Bridges JW, et al. Species differences in the metabolism and excretion of sulphasomidine andsulphamethomidine. Biochem J. 1969 Jan;111(2):173-9.

Title: Melander A, et, al. Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections. Acta Med Scand. 1982;211(5):361-4.

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SDS
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