51543-38-5 | [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-a-methyl-, (±)-

Title: Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution.

Journal: Journal of medicinal chemistry 20160512

Title: Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies.

Journal: European journal of medicinal chemistry 20160215

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: CYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drug.

Journal: PloS one 20150101

Title: CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques.

Journal: Biochemical pharmacology 20140915

Title: A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101

Title: CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study.

Journal: Current Alzheimer research 20130901

Title: Fatal hypersensitivity reaction to an oral spray of flurbiprofen: a case report.

Journal: Journal of clinical pharmacy and therapeutics 20130801

Title: Implication of novel CYP2C9*57 (p.Asn204His) variant in coumarin hypersensitivity.

Journal: Thrombosis research 20130601

Title: Use of micropatterned cocultures to detect compounds that cause drug-induced liver injury in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130301

Title: Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking.

Journal: Journal of molecular modeling 20121201

Title: Study of the solvent effects on the molecular structure and CO stretching vibrations of flurbiprofen.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

Title: Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: divergence from in vitro results.

Journal: Clinical pharmacology and therapeutics 20121101

Title: Non-selective inhibition of cyclooxygenase enzymes by aminoacetylenic isoindoline 1,3-diones.

Journal: Inflammation & allergy drug targets 20121001

Title: Stereoselective binding of flurbiprofen enantiomers and their methyl esters to human serum albumin studied by time-resolved phosphorescence.

Journal: Chirality 20121001

Title: Flurbiprofen axetil promotes neuroprotection by activation of cerebral peroxisome proliferator-activated receptor gamma after focal cerebral ischemia in rats.

Journal: Chinese medical journal 20121001

Title: Effect of temperature, cosolvent, and added drug on Pluronic-flurbiprofen micellization.

Journal: The journal of physical chemistry. B 20120920

Title: 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3.

Journal: Journal of medicinal chemistry 20120913

Title: Excited-state interactions in diastereomeric flurbiprofen-thymine dyads.

Journal: The journal of physical chemistry. A 20120906

Title: Transglycosylated rutin-specific non-surface-active nanostructure affects absorption enhancement of flurbiprofen.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120901

Title: Formulation, evaluation and pharmacokinetics of colon targeted pulsatile system of flurbiprofen.

Journal: Journal of drug targeting 20120901

Title: Drug-induced TINU syndrome and genetic characterization.

Journal: Clinical nephrology 20120901

Title: Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy.

Journal: Journal of anesthesia 20120801

Title: Effect of P450 oxidoreductase variants on the metabolism of model substrates mediated by CYP2C9.1, CYP2C9.2, and CYP2C9.3.

Journal: Pharmacogenetics and genomics 20120801

Title: Intra-articular delivery of genipin cross-linked chitosan microspheres of flurbiprofen: preparation, characterization, in vitro and in vivo studies.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801

Title: Non-steroidal anti-inflammatory drugs reduce the stress response during sevoflurane anesthesia.

Journal: Acta anaesthesiologica Scandinavica 20120801

Title: Nano-pulverization of poorly water soluble compounds with low melting points by a rotation/revolution pulverizer.

Journal: Die Pharmazie 20120801

Title: Modulation of drug release from nanocarriers loaded with a poorly water soluble drug (flurbiprofen) comprising natural waxes.

Journal: Die Pharmazie 20120801

Title: Beyond benzyl grignards: facile generation of benzyl carbanions from styrenes.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120723

Title: Simultaneously improving the mechanical properties, dissolution performance, and hygroscopicity of ibuprofen and flurbiprofen by cocrystallization with nicotinamide.

Journal: Pharmaceutical research 20120701

Title: Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.

Journal: European journal of medicinal chemistry 20120701

Title: Comparative study of three methods for affinity measurements: capillary electrophoresis coupled with UV detection and mass spectrometry, and direct infusion mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20120701

Title: Determination of non-steroidal anti-inflammatory drugs in urine by the combination of stir membrane liquid-liquid-liquid microextraction and liquid chromatography.

Journal: Analytical and bioanalytical chemistry 20120701

Title: Enantiomeric resolution of ibuprofen and flurbiprofen in human plasma by SPE-chiral HPLC methods.

Journal: Combinatorial chemistry & high throughput screening 20120701

Title: NSAIDs induce apoptosis in nonproliferating ovarian cancer cells and inhibit tumor growth in vivo.

Journal: IUBMB life 20120701

Title: Chiral amines as reagents for HPLC-MS enantioseparation of chiral carboxylic acids.

Journal: Journal of separation science 20120701

Title: Flurbiprofen without a prescription for dysmenorrhoea: rejected by French Health Products Agency.

Journal: Prescrire international 20120701

Title: An examination of the thermodynamics of fusion, vaporization, and sublimation of (R,S)- and (R)-flurbiprofen by correlation gas chromatography.

Journal: Journal of pharmaceutical sciences 20120601

Title: Nanocomposite formation between alpha-glucosyl stevia and surfactant improves the dissolution profile of poorly water-soluble drug.

Journal: International journal of pharmaceutics 20120530

Title: Building a three-dimensional model of CYP2C9 inhibition using the Autocorrelator: an autonomous model generator.

Journal: Journal of chemical information and modeling 20120525

Title: Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells.

Journal: Experimental eye research 20120501

Title: Takotsubo cardiomyopathy during ambulatory anesthesia for bladder hydrodistension therapy -A case report-.

Journal: Korean journal of anesthesiology 20120501

Title: Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society.

Journal: Neurology 20120424

Title: Cytoprotective effect of nonsteroidal antiinflammatory drugs in rat brain slices subjected to reoxygenation after oxygen-glucose deprivation.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411

Title: First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.

Journal: The Journal of biological chemistry 20120406

Title: miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver.

Journal: The EMBO journal 20120404

Title: Glycosylation of human cyclooxygenase-2 (COX-2) decreases the efficacy of certain COX-2 inhibitors.

Journal: Pharmacological research 20120401

Title: Non-steroidal anti-inflammatory drugs and gastroprotection with proton pump inhibitors: a focus on ketoprofen/omeprazole.

Journal: Clinical drug investigation 20120401

Title: Effect of olive oil on transdermal penetration of flurbiprofen from topical gel as enhancer.

Journal: Pakistan journal of pharmaceutical sciences 20120401

Title: Seeing it through: translational validation of new medical imaging modalities.

Journal: Biomedical optics express 20120401

Title: Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.

Journal: Journal of chemical information and modeling 20120326

Title: Tranexamic acid: a review of its use in the treatment of hyperfibrinolysis.

Journal: Drugs 20120326

Title: Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.

Journal: Journal of medicinal chemistry 20120308

Title: Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?

Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120301

Title: Novel surface-modified nanostructured lipid carriers with partially deacetylated water-soluble chitosan for efficient ocular delivery.

Journal: Journal of pharmaceutical sciences 20120301

Title: Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot.

Journal: Clinical pharmacology and therapeutics 20120301

Title: Cyclodextrins as a chiral mobile phase additive in nano-liquid chromatography: comparison of reversed-phase silica monolithic and particulate capillary columns.

Journal: Analytical and bioanalytical chemistry 20120301

Title: Amino acid and vitamin supplementation improved health conditions in elderly participants.

Journal: Journal of clinical biochemistry and nutrition 20120301

Title: Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease.

Journal: The Cochrane database of systematic reviews 20120215

Title: The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.

Journal: Brain research 20120203

Title: R-flurbiprofen, a novel nonsteroidal anti-inflammatory drug, decreases cell proliferation and induces apoptosis in pituitary adenoma cells in vitro.

Journal: Journal of neuro-oncology 20120201

Title: Improved and safe transcorneal delivery of flurbiprofen by NLC and NLC-based hydrogels.

Journal: Journal of pharmaceutical sciences 20120201

Title: Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS).

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120201

Title: Immunodetection of cyclooxygenase-2 (COX-2) is restricted to tissue macrophages in normal rat liver and to recruited mononuclear phagocytes in liver injury and cholangiocarcinoma.

Journal: Histochemistry and cell biology 20120201

Title: A new methodology for simultaneous quantification of total-Aβ, Aβx-38, Aβx-40, and Aβx-42 by column-switching LC/MS/MS.

Journal: Analytical and bioanalytical chemistry 20120201

Title: Preemptive analgesic effects of flurbiprofen axetil in patients undergoing radical resection of esophageal carcinoma via the left thoracic approach.

Journal: Chinese medical journal 20120201

Title: Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery.

Journal: Journal of ethnopharmacology 20120106

Title: Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid drugs.

Journal: Drug development and industrial pharmacy 20120101

Title: Marine sponge Hymeniacidon sp. amphilectane metabolites potently inhibit rat brain microglia thromboxane B2 generation.

Journal: Bioorganic & medicinal chemistry 20120101

Title: Aspirin: pharmacology and clinical applications.

Journal: Thrombosis 20120101

Title: Development of novel flurbiprofen-loaded solid self-microemulsifying drug delivery system using gelatin as solid carrier.

Journal: Journal of microencapsulation 20120101

Title: Presenilin is the molecular target of acidic γ-secretase modulators in living cells.

Journal: PloS one 20120101

Title: Influence of skin thickness on the in vitro permeabilities of drugs through Sprague-Dawley rat or Yucatan micropig skin.

Journal: Biological & pharmaceutical bulletin 20120101

Title: The use of an artificial skin model to study transdermal absorption of drugs in inflamed skin.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology.

Journal: Frontiers in pharmacology 20120101

Title: Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models.

Journal: Journal of neuroinflammation 20120101

Title: Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial.

Journal: BMJ open 20120101

Title: Dendrimers bind antioxidant polyphenols and cisplatin drug.

Journal: PloS one 20120101

Title: A randomised, two-period, cross-over, open-label study to evaluate the pharmacokinetic profiles of single doses of two different flurbiprofen 8.75-mg lozenges in healthy volunteers.

Journal: Pharmacology 20120101

Title: Therapeutic effect of CHF5074, a new γ-secretase modulator, in a mouse model of scrapie.

Journal: Prion 20120101

Title: Role of hydroxypropyl-β-cyclodextrin on freeze-dried and gamma-irradiated PLGA and PLGA-PEG diblock copolymer nanospheres for ophthalmic flurbiprofen delivery.

Journal: International journal of nanomedicine 20120101

Title: NO-NSAIDs. Part 3: nitric oxide-releasing prodrugs of non-steroidal anti-inflammatory drugs.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: Flurbiprofen.

Journal: Profiles of drug substances, excipients, and related methodology 20120101

Title: Disruption of the serotonergic system after neonatal hypoxia-ischemia in a rodent model.

Journal: Neurology research international 20120101

Title: Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: a cohort study.

Journal: PloS one 20120101

Title: Detection of herplex simplex virus-1 and -2 in cardiac myxomas.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Cyclodextrin-containing polymers: versatile platforms of drug delivery materials.

Journal: Journal of drug delivery 20120101

Title: Chemically modified tetracyclines: Novel therapeutic agents in the management of chronic periodontitis.

Journal: Indian journal of pharmacology 20120101

Title: Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: A new investigation for some steroidal derivatives as anti-Alzheimer agents.

Journal: International journal of biological macromolecules 20120101

Title: Biogenic and synthetic polyamines bind cationic dendrimers.

Journal: PloS one 20120101

Title: A review: inflammatory process in Alzheimer's disease, role of cytokines.

Journal: TheScientificWorldJournal 20120101

Title: Comparative QSAR analysis of cyclo-oxygenase2 inhibiting drugs.

Journal: Bioinformation 20120101

Title: Update on twice-daily bromfenac sodium sesquihydrate to treat postoperative ocular inflammation following cataract extraction.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide.

Journal: International journal of nanomedicine 20120101

Title: Drug Eruptions: An 8-year Study Including 106 Inpatients at a Dermatology Clinic in Turkey.

Journal: Indian journal of dermatology 20120101

Title: γ-Secretase modulator in Alzheimer's disease: shifting the end.

Journal: Journal of Alzheimer's disease : JAD 20120101

Title: Flurbiprofen, a cyclooxygenase inhibitor, protects mice from hepatic ischemia/reperfusion injury by inhibiting GSK-3β signaling and mitochondrial permeability transition.

Journal: Molecular medicine (Cambridge, Mass.) 20120101

Title: Biocatalytic synthesis of flavones and hydroxyl-small molecules by recombinant Escherichia coli cells expressing the cyanobacterial CYP110E1 gene.

Journal: Microbial cell factories 20120101

Title: Equilibrium and release properties of aqueous dispersions of non-steroidal anti-inflammatory drugs complexed with polyelectrolyte eudragit e 100.

Journal: Scientia pharmaceutica 20120101

Title: Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.

Journal: PloS one 20120101

Title: Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.

Journal: The Journal of international medical research 20120101

Title: [Development of novel methods for preparing chiral non-steroidal anti-inflammatory drugs (NSAIDs) by asymmetric esterification].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

Title: Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen.

Journal: Biochemical pharmacology 20111201

Title: Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3.

Journal: Biopharmaceutics & drug disposition 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: [Effect of continuous intravenous infusion of flurbiprofen axetil and tramadol hydrochloride for postoperative pain management of laparoscopic colectomy].

Journal: Masui. The Japanese journal of anesthesiology 20111201

Title: Impact and Therapeutic Potential of PPARs in Alzheimer's Disease.

Journal: Current neuropharmacology 20111201

Title: [Gamma-secretase inhibitors and modulators].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20111201

Title: NSAID-based γ-secretase modulators do not bind to the amyloid-β polypeptide.

Journal: Biochemistry 20111129

Title: Comparison of solid self-microemulsifying drug delivery system (solid SMEDDS) prepared with hydrophilic and hydrophobic solid carrier.

Journal: International journal of pharmaceutics 20111128

Title: Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein.

Journal: The Journal of biological chemistry 20111118

Title: Naproxen-induced fixed drug eruption: a case report.

Journal: Human & experimental toxicology 20111101

Title: Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).

Journal: Prostaglandins & other lipid mediators 20111101

Title: The structure of NS-398 bound to cyclooxygenase-2.

Journal: Journal of structural biology 20111101

Title: Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20111101

Title: (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2.

Journal: Nature chemical biology 20111101

Title: Multiple applications of flurbiprofen and chlorhexidine chips in patients with chronic periodontitis: a randomized, double blind, parallel, 2-arms clinical trial.

Journal: Journal of clinical periodontology 20111101

Title: Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative.

Journal: International journal of pharmaceutics 20111031

Title: [Effect of flurbiprofen combined different concentrations of ropivacaine local infiltration on postoperative analgesia after laparoscopic cholecystectomy].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20111018

Title: Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways.

Journal: Chemical reviews 20111012

Title: Flurbiprofen axetil enhances analgesic effect of fentanyl associated with increase in β-endorphin levels.

Journal: Journal of anesthesia 20111001

Title: Effect of flurbiprofen, metoclopramide and droperidol for nausea and emesis during cesarean section under spinal anesthesia.

Journal: Journal of anesthesia 20111001

Title: Notch post-translationally regulates β-catenin protein in stem and progenitor cells.

Journal: Nature cell biology 20111001

Title: Enantioseparation of organic acids of pharmaceutical interest using eremomycin as a chiral selector.

Journal: Electrophoresis 20111001

Title: The γ-secretase modulator CHF5074 reduces the accumulation of native hyperphosphorylated tau in a transgenic mouse model of Alzheimer's disease.

Journal: Journal of molecular neuroscience : MN 20110901

Title: A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy.

Journal: Pharmacological research 20110901

Title: Aggravation by paroxetine, a selective serotonin reuptake inhibitor, of antral lesions generated by nonsteroidal anti-inflammatory drugs in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20110901

Title: Chiral separation of flurbiprofen enantiomers by preparative and simulated moving bed chromatography.

Journal: Chirality 20110901

Title: NSAID-derived γ-secretase modulation requires an acidic moiety on the carbazole scaffold.

Journal: Bioorganic & medicinal chemistry 20110815

Title: Lack of enantiomeric influence on the brain cytoprotective effect of ibuprofen and flurbiprofen.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110801

Title: Flurbiprofen axetil, nasal polyps, and status asthmaticus: an unusual case report.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20110801

Title: Switching the microglial harmful phenotype promotes lifelong restoration of subtantia nigra dopaminergic neurons from inflammatory neurodegeneration in aged mice.

Journal: Rejuvenation research 20110801

Title: Structure and dynamics of the membrane-bound cytochrome P450 2C9.

Journal: PLoS computational biology 20110801

Title: The elements of human cyclin D1 promoter and regulation involved.

Journal: Clinical epigenetics 20110801

Title: Flurbiprofen encapsulation using pluronic triblock copolymers.

Journal: Langmuir : the ACS journal of surfaces and colloids 20110705

Title: Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol.

Journal: Minerva anestesiologica 20110701

Title: Novel NSAIDs ophthalmic formulation: flurbiprofen axetil emulsion with low irritancy and improved anti-inflammation effect.

Journal: International journal of pharmaceutics 20110630

Title: The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats.

Journal: Biochemical and biophysical research communications 20110617

Title: Interaction between drug loaded polyaspartamide-polylactide-polysorbate based micelles and cell membrane models: a calorimetric study.

Journal: Molecular pharmaceutics 20110606

Title: Multivariate optimization of formulation variables influencing flurbiprofen proniosomes characteristics.

Journal: Journal of pharmaceutical sciences 20110601

Title: Anesthetic management of a patient with narcolepsy.

Journal: Journal of anesthesia 20110601

Title: Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats.

Journal: American journal of veterinary research 20110601

Title: Plasma asymmetric dimethylarginine predicts restenosis after coronary angioplasty.

Journal: Archives of medical science : AMS 20110601

Title: Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.

Journal: Chemico-biological interactions 20110530

Title: Drug metabolism in hemorrhagic shock: pharmacokinetics of selective markers of cytochrome-P450 2C9, 2D6, and 3A4 enzyme activities in a porcine model.

Journal: The Journal of surgical research 20110515

Title: The neuroprotective effects of NMDAR antagonist, ifenprodil and ASIC1a inhibitor, flurbiprofen on post-ischemic cerebral injury.

Journal: Brain research 20110510

Title: Synthesis of α-aryl nitriles through palladium-catalyzed decarboxylative coupling of cyanoacetate salts with aryl halides and triflates.

Journal: Angewandte Chemie (International ed. in English) 20110502

Title: R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's disease as determined by MEMRI.

Journal: Magnetic resonance in medicine 20110501

Title: Design and evaluation of ocusert for controlled delivery of flurbiprofen sodium.

Journal: Current eye research 20110501

Title: Combinations of protein-chemical complex structures reveal new targets for established drugs.

Journal: PLoS computational biology 20110501

Title: Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.

Journal: Journal of medicinal chemistry 20110414

Title: The butterfly effect: a physical phenomenon of hypromellose matrices during dissolution and the factors affecting its occurrence.

Journal: International journal of pharmaceutics 20110315

Title: Supercritical fluid-assisted preparation of imprinted contact lenses for drug delivery.

Journal: Acta biomaterialia 20110301

Title: Effect of topical 0.03% flurbiprofen and 0.005% latanoprost, alone and in combination, on normal canine eyes.

Journal: Veterinary ophthalmology 20110301

Title: Enhanced solubility and bioavailability of flurbiprofen by cycloamylose.

Journal: Archives of pharmacal research 20110301

Title: A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin.

Journal: Bioorganic & medicinal chemistry 20110215

Title: Cannabinoid system and cyclooxygenases inhibitors.

Journal: Journal of medicine and life 20110215

Title: Effect of process parameters on nanoemulsion droplet size and distribution in SPG membrane emulsification.

Journal: International journal of pharmaceutics 20110214

Title: A UPLC-MS/MS assay of the 'Pittsburgh cocktail': six CYP probe-drug/metabolites from human plasma and urine using stable isotope dilution.

Journal: The Analyst 20110207

Title: ASAS recommendations for collecting, analysing and reporting NSAID intake in clinical trials/epidemiological studies in axial spondyloarthritis.

Journal: Annals of the rheumatic diseases 20110201

Title: Wormlike micellar aggregates of saponins from Ilex paraguariensis A. St. Hil. (mate): a characterisation by cryo-TEM, rheology, light scattering and small-angle neutron scattering.

Journal: Journal of pharmaceutical sciences 20110201

Title: Determination of pharmacokinetics of flurbiprofen in Pakistani population using modified HPLC method.

Journal: Journal of chromatographic science 20110201

Title: Optimizing flurbiprofen-loaded NLC by central composite factorial design for ocular delivery.

Journal: Nanotechnology 20110128

Title: Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite.

Journal: Journal of pharmaceutical and biomedical analysis 20110125

Title: Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system.

Journal: International journal of pharmaceutics 20110117

Title: Optimization of isocratic supercritical fluid chromatography for enantiomer separation.

Journal: Journal of chromatography. A 20110107

Title: Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen.

Journal: Journal of pharmaceutical sciences 20110101

Title: Structural evaluation of crystalline ternary γ-cyclodextrin complex.

Journal: Journal of pharmaceutical sciences 20110101

Title: Physicochemical characterization and in vivo evaluation of flurbiprofen-loaded solid dispersion without crystalline change.

Journal: Drug delivery 20110101

Title: Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Acrylic acid-methyl methacrylate (2.5:7.5/2:8) enteric copolymer for colon targeted drug delivery.

Journal: Journal of materials science. Materials in medicine 20110101

Title: Transgenic AD model mice, effects of potential anti-AD treatments on inflammation, and pathology.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Use of non-steroidal anti-inflammatory drugs and prostate cancer risk: a population-based nested case-control study.

Journal: PloS one 20110101

Title: Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation.

Journal: Molecular neurodegeneration 20110101

Title: The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey.

Journal: PloS one 20110101

Title: IL-1β stimulates COX-2 dependent PGE₂ synthesis and CGRP release in rat trigeminal ganglia cells.

Journal: PloS one 20110101

Title: Transfer kinetics from colloidal drug carriers and liposomes to biomembrane models: DSC studies.

Journal: Journal of pharmacy & bioallied sciences 20110101

Title: Mucoadhesive drug delivery systems.

Journal: Journal of pharmacy & bioallied sciences 20110101

Title: Effects of flurbiprofen on CRP, TNF-α, IL-6, and postoperative pain of thoracotomy.

Journal: International journal of medical sciences 20110101

Title: Variation assessment for in vitro permeabilities through Yucatan micropig skin.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Investigational drugs for the treatment of AD: what can we learn from negative trials?

Journal: Alzheimer's research & therapy 20110101

Title: Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes.

Journal: Journal of translational medicine 20110101

Title: Management of Intraoperative Miosis during Pediatric Cataract Surgery using Healon 5.

Journal: Middle East African journal of ophthalmology 20110101

Title: Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease.

Journal: Molecular neurodegeneration 20110101

Title: Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes.

Journal: PloS one 20110101

Title: Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Usefulness of rat skin as a substitute for human skin in the in vitro skin permeation study.

Journal: Experimental animals 20110101

Title: Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery.

Journal: International journal of nanomedicine 20110101

Title: Biocompatibility and biodegradation studies of subconjunctival implants in rabbit eyes.

Journal: PloS one 20110101

Title: Lack of preemptive analgesia by intravenous flurbiprofen in thyroid gland surgery: a randomized, double-blind and placebo-controlled clinical trial.

Journal: International journal of medical sciences 20110101

Title: Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma.

Journal: PloS one 20110101

Title: Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.

Journal: PloS one 20110101

Title: Characterization of a novel and spontaneous mouse model of inflammatory arthritis.

Journal: Arthritis research & therapy 20110101

Title: Transumbilical laparo-endoscopic single site surgery for adrenal cortical adenoma inducing primary aldosteronism: initial experience.

Journal: BMC research notes 20110101

Title: Dissolution behavior of β-cyclodextrin molecular inclusion complexes of aceclofenac.

Journal: Journal of pharmacy & bioallied sciences 20110101

Title: Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease.

Journal: PloS one 20110101

Title: Functional evaluation of genetic and environmental regulators of p450 mRNA levels.

Journal: PloS one 20110101

Title: Minocycline and doxycycline therapy in community patients with rheumatoid arthritis: prescribing patterns, patient-level determinants of use, and patient-reported side effects.

Journal: Arthritis research & therapy 20110101

Title: The effect of ketoprofen in chronic periodontitis: A clinical double-blind study.

Journal: Journal of Indian Society of Periodontology 20110101

Title: In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate.

Journal: International journal of nanomedicine 20110101

Title: Anti-UVC irradiation and metal chelation properties of 6-benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: an implications for anti-cataract agent.

Journal: International journal of molecular sciences 20110101

Title: Interacting with γ-secretase for treating Alzheimer's disease: from inhibition to modulation.

Journal: Current medicinal chemistry 20110101

Title: A systematic review of the effects of sedatives and anesthetics in patients with obstructive sleep apnea.

Journal: Journal of anaesthesiology, clinical pharmacology 20110101

Title: New surface-modified solid lipid nanoparticles using N-glutaryl phosphatidylethanolamine as the outer shell.

Journal: International journal of nanomedicine 20110101

Title: Development and evaluation of mucoadhesive buccal patches of flurbiprofen.

Journal: Acta poloniae pharmaceutica 20110101

Title: Different cellular effects of four anti-inflammatory eye drops on human corneal epithelial cells: independent in active components.

Journal: Molecular vision 20110101

Title: A simple high-performance liquid chromatographic practical approach for determination of flurbiprofen.

Journal: Journal of advanced pharmaceutical technology & research 20110101

Title: Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives.

Journal: Pharmacognosy reviews 20110101

Title: Preparation of Fluconazole β-Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation.

Journal: ISRN pharmaceutics 20110101

Title: Enhance transdermal delivery of flurbiprofen via microemulsions: Effects of different types of surfactants and cosurfactants.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Title: Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.

Journal: Chemical research in toxicology 20101220

Title: Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC.

Journal: Colloids and surfaces. B, Biointerfaces 20101201

Title: Neuroprotective effect of flurbiprofen in focal cerebral ischemia: the possible role of ASIC1a.

Journal: Neuropharmacology 20101201

Title: Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20101201

Title: Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2.

Journal: Chemosphere 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Evaluation of percutaneous permeation of flurbiprofen and ketoprofen after application of transdermal patches using a lateral sectioning approach in hairless rats.

Journal: Pharmaceutical development and technology 20101201

Title: A potential nitrergic mechanism of action for indomethacin, but not of other COX inhibitors: relevance to indomethacin-sensitive headaches.

Journal: The journal of headache and pain 20101201

Title: Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood.

Journal: Anesthesia and analgesia 20101201

Title: NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPK-p75(NTR) pathway.

Journal: Molecular cancer research : MCR 20101201

Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

Journal: Healthcare informatics research 20101201

Title: Drug development for Alzheimer's disease: recent progress.

Journal: Experimental neurobiology 20101201

Title: Improved drug loading/release capacities of commercial contact lenses obtained by supercritical fluid assisted molecular imprinting methods.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20101120

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Validation of individual quantitative methods for determination of cytochrome P450 probe substrates in human dried blood spots with HPLC-MS/MS.

Journal: Bioanalysis 20101101

Title: [Population pharmacokinetic modeling of flurbiprofen].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101101

Title: Does stereochemistry influence transdermal permeation of flurbiprofen through the rat skin?

Journal: Archives of dermatological research 20101001

Title: Transglycosylated stevia and hesperidin as pharmaceutical excipients: dramatic improvement in drug dissolution and bioavailability.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101001

Title: Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury.

Journal: International journal of clinical practice 20101001

Title: Nepafenac-assisted mydriasis in a rabbit model.

Journal: Journal of cataract and refractive surgery 20101001

Title: Are we prepared to deal with the Alzheimer's disease pandemic?

Journal: Clinical pharmacology and therapeutics 20101001

Title: Plasma and cerebrospinal fluid pharmacokinetics of flurbiprofen in children.

Journal: British journal of clinical pharmacology 20101001

Title: Effect of autogenous cortical bone grafting in conjunction with guided tissue regeneration in the treatment of intraosseous periodontal defects.

Journal: European journal of dentistry 20101001

Title: Acrylic acid-methyl methacrylate copolymer for oral prolonged drug release.

Journal: Journal of materials science. Materials in medicine 20100901

Title: Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers.

Journal: Biochemistry 20100824

Title: Small scale screening to determine the ability of different polymers to inhibit drug crystallization upon rapid solvent evaporation.

Journal: Molecular pharmaceutics 20100802

Title: Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents.

Journal: Scandinavian journal of gastroenterology 20100801

Title: Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability.

Journal: Acta pharmacologica Sinica 20100801

Title: Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters.

Journal: PLoS neglected tropical diseases 20100801

Title: [Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701

Title: Enhancement of dissolution and bioavailability of flurbiprofen by low molecular weight chitosans.

Journal: Die Pharmazie 20100701

Title: [Drug therapy for Alzheimer's disease].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20100701

Title: Improvement of dissolution and absorption properties of poorly water-soluble drug by preparing spray-dried powders with alpha-glucosyl hesperidin.

Journal: International journal of pharmaceutics 20100615

Title: Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of flurbiprofen.

Journal: Chirality 20100601

Title: R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100601

Title: Analgesic effect of parecoxib and flurbiprofen axetil for patients undergoing laparoscopic cholecystectomy and their influences on platelet aggregation.

Journal: Chinese medical journal 20100601

Title: Effect of centchroman coadministration on the pharmacokinetics of metformin in rats.

Journal: Indian journal of pharmacology 20100601

Title: Use of a robust dehydrogenase from an archael hyperthermophile in asymmetric catalysis-dynamic reductive kinetic resolution entry into (S)-profens.

Journal: Journal of the American Chemical Society 20100505

Title: Encapsulation and characterization of controlled release flurbiprofen loaded microspheres using beeswax as an encapsulating agent.

Journal: Journal of materials science. Materials in medicine 20100501

Title: Site of metabolism prediction on cytochrome P450 2C9: a knowledge-based docking approach.

Journal: Journal of computer-aided molecular design 20100501

Title: Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides.

Journal: Current eye research 20100501

Title: Simultaneous dissolution of naproxen and flurbiprofen from a novel ternary gamma-cyclodextrin complex.

Journal: Chemical & pharmaceutical bulletin 20100501

Title: Confirmatory analysis of non-steroidal anti-inflammatory drugs in bovine milk by high-performance liquid chromatography with fluorescence detection.

Journal: Journal of chromatography. A 20100423

Title: Comparison of randomized treatments for late whiplash.

Journal: Neurology 20100413

Title: Effect of counter-ions and penetration enhancers on the skin permeation of flurbiprofen.

Journal: Journal of pharmaceutical sciences 20100401

Title: Disease-modifying drug fails in Alzheimer's study.

Journal: The Harvard mental health letter 20100401

Title: [The effect of flurbiprofen axetil on laparoscopic cholecystectomy].

Journal: Zhonghua yi xue za zhi 20100323

Title: Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs.

Journal: Pflugers Archiv : European journal of physiology 20100301

Title: Tarenflurbil for Alzheimer's disease: a 'shot on goal' that missed.

Journal: The Lancet. Neurology 20100301

Title: Green hydrophilic interaction chromatography using ethanol-water-carbon dioxide mixtures.

Journal: Journal of separation science 20100301

Title: Comparative bioavailability and pharmacokinetics of investigational enteric- and film-coated formulations of flurbiprofen 100-mg tablets: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy Pakistani male volunteers.

Journal: Clinical therapeutics 20100301

Title: Monocarboxylate transport in human corneal epithelium and cell lines.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100219

Title: COX-2 specific inhibitors enhance the cytotoxic effects of pemetrexed in mesothelioma cell lines.

Journal: Lung cancer (Amsterdam, Netherlands) 20100201

Title: R-flurbiprofen reverses multidrug resistance, proliferation and metastasis in gastric cancer cells by p75(NTR) induction.

Journal: Molecular pharmaceutics 20100201

Title: The disposition of free and niosomally encapsulated Rac-flurbiprofen in dairy bovines.

Journal: Journal of veterinary pharmacology and therapeutics 20100201

Title: Use of a mydriatic cocktail with a wick for preoperative mydriasis in cataract surgery: a prospective randomised controlled trial.

Journal: Eye (London, England) 20100101

Title: Release of PLGA-encapsulated dexamethasone from microsphere loaded porous surfaces.

Journal: Journal of materials science. Materials in medicine 20100101

Title: Eltrombopag, an oral thrombopoietin receptor agonist, has no impact on the pharmacokinetic profile of probe drugs for cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C9 and CYP2C19 in healthy men: a cocktail analysis.

Journal: European journal of clinical pharmacology 20100101

Title: Bovine beta-lactoglobulin acts as an acid-resistant drug carrier by exploiting its diverse binding regions.

Journal: Biological chemistry 20100101

Title: Current approach in diagnosis and management of anterior uveitis.

Journal: Indian journal of ophthalmology 20100101

Title: Caldesmon regulates the motility of vascular smooth muscle cells by modulating the actin cytoskeleton stability.

Journal: Journal of biomedical science 20100101

Title: Kinin B1 receptors contributes to acute pain following minor surgery in humans.

Journal: Molecular pain 20100101

Title: CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Enhanced oral bioavailability of flurbiprofen by combined use of micelle solution and inclusion compound.

Journal: Archives of pharmacal research 20100101

Title: Enhanced oral bioavailability of flurbiprofen by combined use of micelle solution and inclusion compound.

Journal: Archives of pharmacal research 20100101

Title: Sumatriptan-naproxen fixed combination for acute treatment of migraine: a critical appraisal.

Journal: Drug design, development and therapy 20100101

Title: Immediate hypersensitivity reaction to a single oral dose of flurbiprofen.

Journal: Journal of postgraduate medicine 20100101

Title: Optimal identification of semi-rigid domains in macromolecules from molecular dynamics simulation.

Journal: PloS one 20100101

Title: R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids.

Journal: PloS one 20100101

Title: Explaining the atypical reaction profiles of heme enzymes with a novel mechanistic hypothesis and kinetic treatment.

Journal: PloS one 20100101

Title: Presenilin/gamma-Secretase and Inflammation.

Journal: Frontiers in aging neuroscience 20100101

Title: NSAIDs: How they Work and their Prospects as Therapeutics in Alzheimer's Disease.

Journal: Frontiers in aging neuroscience 20100101

Title: The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol.

Journal: BMC clinical pharmacology 20100101

Title: Influence of cyclodextrin complexation with NSAIDs on NSAID/cold stress-induced gastric ulceration in rats.

Journal: International journal of medical sciences 20100101

Title: The Nuclear Receptor PPARgamma as a Therapeutic Target for Cerebrovascular and Brain Dysfunction in Alzheimer's Disease.

Journal: Frontiers in aging neuroscience 20100101

Title: Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment?

Journal: Frontiers in aging neuroscience 20100101

Title: Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma.

Journal: Respiratory research 20100101

Title: Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Single dose dipyrone for acute postoperative pain.

Journal: The Cochrane database of systematic reviews 20100101

Title: Antidiarrhoeal Activity of the Alcoholic Extract of the Leaves of Butea frondosa Koen. Ex Roxb.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Brain amyloid β protein and memory disruption in Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: NSAIDs may protect against age-related brain atrophy.

Journal: Frontiers in aging neuroscience 20100101

Title: Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Cataract surgery under topical anesthesia using 2% lignocaine jelly and intracameral lignocaine: is manual small incision cataract surgery comparable to clear corneal phacoemulsification?

Journal: Indian journal of ophthalmology 20100101

Title: Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects.

Journal: International journal of molecular sciences 20100101

Title: Cytochrome P450 reductase: a harbinger of diffusible reduced oxygen species.

Journal: PloS one 20100101

Title: Non-contraceptive applications of the levonorgestrel intrauterine system.

Journal: International journal of women's health 20100101

Title: Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

Journal: Journal of neuroinflammation 20100101

Title: Microencapsulation: an acclaimed novel drug-delivery system for NSAIDs in arthritis.

Journal: Critical reviews in therapeutic drug carrier systems 20100101

Title: Pharmacophore elucidation and molecular docking studies on 5-phenyl-1-(3-pyridyl)-1h-1,2,4-triazole-3-carboxylic acid derivatives as COX-2 inhibitors.

Journal: Scientia pharmaceutica 20100101

Title: Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease.

Journal: Alzheimer's research & therapy 20100101

Title: Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch.

Journal: Journal of pain research 20100101

Title: The effect of flurbiprofen as prophylactic analgesic before hysterosalpingography.

Journal: The Journal of international medical research 20100101

Title: [Ion-sensitive nanoemulsion-in situ gel system for ophthalmic delivery of flurbiprofen axetil].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100101

Title: The link between periodontal disease and cardiovascular disease: How far we have come in last two decades ?

Journal: Journal of Indian Society of Periodontology 20100101

Title: Risk of Upper Gastrointestinal Bleeding in a Cohort of New Users of Low-Dose ASA for Secondary Prevention of Cardiovascular Outcomes.

Journal: Frontiers in pharmacology 20100101

Title: Effect of intensive non-surgical treatment on the level of serum inflammatory markers in advanced periodontitis.

Journal: Journal of dentistry (Tehran, Iran) 20100101

Title: Therapeutic and cosmeceutical potential of ethosomes: An overview.

Journal: Journal of advanced pharmaceutical technology & research 20100101

Title: Microsponges: A novel strategy for drug delivery system.

Journal: Journal of advanced pharmaceutical technology & research 20100101

Title: Niosome: A future of targeted drug delivery systems.

Journal: Journal of advanced pharmaceutical technology & research 20100101

Title: Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project.

Journal: Clinical pharmacology : advances and applications 20100101

Title: Microencapsulation of flavors in carnauba wax.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Pluronic lecithin organogel as a topical drug delivery system.

Journal: Drug delivery 20100101

Title: Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2.

Journal: Biochemistry 20091222

Title: Suzuki-Miyaura coupling of aryl carbamates, carbonates, and sulfamates.

Journal: Journal of the American Chemical Society 20091216

Title: Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial.

Journal: JAMA 20091216

Title: Late-life dementias: does this unyielding global challenge require a broader view?

Journal: JAMA 20091216

Title: Enantioseparation of flurbiprofen on amylose-derived chiral stationary phase by supercritical fluid chromatography.

Journal: Journal of chromatography. A 20091211

Title: Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo.

Journal: Neurochemical research 20091201

Title: Possible involvement of microglia containing cyclooxygenase-1 in the accumulation of gonadotrophin-releasing hormone in the preoptic area in female rats.

Journal: Journal of neuroendocrinology 20091201

Title: Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology.

Journal: Drug development and industrial pharmacy 20091201

Title: New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part II.

Journal: Current drug metabolism 20091201

Title: New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part I.

Journal: Current drug metabolism 20091201

Title: An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.

Journal: Biochemistry 20091124

Title: Two pathways for cyclooxygenase-2 protein degradation in vivo.

Journal: The Journal of biological chemistry 20091106

Title: Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach.

Journal: Journal of pharmaceutical sciences 20091101

Title: NO-flurbiprofen reduces amyloid-beta, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade.

Journal: Journal of neurochemistry 20091101

Title: Selective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels.

Journal: Journal of neurochemistry 20091101

Title: [Effects of preemptive analgesia with flurbiprofen on the blood sugar and interleukin-6 of patients after radical excision of breast cancer].

Journal: Zhonghua yi xue za zhi 20091027

Title: Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid.

Journal: Journal of neurochemistry 20091001

Title: Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism.

Journal: The journal of physical chemistry. B 20091001

Title: Improvement of dissolution property of poorly water-soluble drug by supercritical freeze granulation.

Journal: Chemical & pharmaceutical bulletin 20091001

Title: Allergen-induced airway inflammation and its therapeutic intervention.

Journal: Allergy, asthma & immunology research 20091001

Title: Tramadol and flurbiprofen depress the cytotoxicity of cisplatin via their effects on gap junctions.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090915

Title: Improvement of oral bioavailability of flurbiprofen from flurbiprofen/beta-cyclodextrin inclusion complex by action of cinnarizine.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090901

Title: Cloud point extraction with surfactant derivatization as an enrichment step prior to gas chromatographic or gas chromatography-mass spectrometric analysis.

Journal: Analytical chemistry 20090815

Title: Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid.

Journal: Biochemistry 20090811

Title: Effect of polymer viscosity on physicochemical properties and ocular tolerance of FB-loaded PLGA nanospheres.

Journal: Colloids and surfaces. B, Biointerfaces 20090801

Title: CYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090801

Title: Influence of prolonged exposure of a short half life non-steroidal anti-inflammatory drugs on gastrointestinal safety.

Journal: Inflammopharmacology 20090801

Title: Pharmacokinetic and bioequivalence comparison between orally disintegrating and conventional tablet formulations of flurbiprofen: a single-dose, randomized-sequence, open-label, two-period crossover study in healthy Chinese male volunteers.

Journal: Clinical therapeutics 20090801

Title: Buccal mucoadhesive tablets of flurbiprofen: Characterization and optimization.

Journal: Drug discoveries & therapeutics 20090801

Title: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells.

Journal: Archives of biochemistry and biophysics 20090715

Title: Solubilization of flurbiprofen within non-ionic Tween 20 surfactant micelles: a 19F and 1H NMR study.

Journal: Physical chemistry chemical physics : PCCP 20090714

Title: pKa and solubility of drugs in water, ethanol, and 1-octanol.

Journal: The journal of physical chemistry. B 20090702

Title: Spectroscopic and DFT studies of flurbiprofen as dimer and its Cu(II) and Hg(II) complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090701

Title: Separation-oriented derivatization of native fluorescent compounds through fluorous labeling followed by liquid chromatography with fluorous-phase.

Journal: Analytical chemistry 20090615

Title: Macrocyclic antibiotics as chiral selectors in the design of enantioselective, potentiometric membrane electrodes for the determination of S-flurbiprofen.

Journal: Analytical and bioanalytical chemistry 20090601

Title: The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats.

Journal: Anesthesia and analgesia 20090601

Title: [Prospective study on anesthesia for lumbar spine surgery--the effectiveness of the perioperative epidural anesthesia with buprenorphine].

Journal: Masui. The Japanese journal of anesthesiology 20090601

Title: [Perioperative anesthetic management of a patient with multiple sclerosis].

Journal: Masui. The Japanese journal of anesthesiology 20090601

Title: Mechanism-based treatments for Alzheimer's disease.

Journal: Dialogues in clinical neuroscience 20090601

Title: [Effect of preemptive analgesia with flurbiprofen axetil on patient-controlled intravenous analgesia with tramadol in patients undergoing postburn plastic surgery].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090601

Title: Translational medicine lessons from flurizan's failure in Alzheimer's disease (AD) trial: Implication for future drug discovery and development for AD.

Journal: Clinical and translational science 20090601

Title: Clonidine in paediatrics - a review.

Journal: Indian journal of anaesthesia 20090601

Title: In situ transient spectroscopy for the study of glucuronidase activity within serum albumin.

Journal: The journal of physical chemistry. B 20090514

Title: Enantiomeric separation of acidic compounds by nano-liquid chromatography with methylated-beta-cyclodextrin as a mobile phase additive.

Journal: Journal of separation science 20090501

Title: Hypersensitivity myocarditis and hypersensitivity coronary syndrome (Kounis syndrome).

Journal: The American journal of emergency medicine 20090501

Title: Enantiorecognition of profens by capillary electrophoresis using a novel chiral selector eremomycin.

Journal: Journal of chromatography. A 20090424

Title: Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data.

Journal: Pharmaceutical research 20090401

Title: What we have learned from the Myriad trials.

Journal: The journal of nutrition, health & aging 20090401

Title: Mosapride and postoperative ileus.

Journal: Diseases of the colon and rectum 20090401

Title: Pretreatment with flurbiprofen axetil, flurbiprofen axetil preceded by venous occlusion, and a mixture of flurbiprofen axetil and propofol in reducing pain on injection of propofol in adult Japanese surgical patients: a prospective, randomized, double-blind, placebo-controlled study.

Journal: Clinical therapeutics 20090401

Title: A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer's disease.

Journal: Aging clinical and experimental research 20090401

Title: Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.

Journal: Chemico-biological interactions 20090316

Title: Cyclomaltoheptaose mixed esters of anti-inflammatory drugs and short-chain fatty acids and study of their enzymatic hydrolysis in vitro.

Journal: Carbohydrate research 20090310

Title: Mechanism of CYP2C9 inhibition by flavones and flavonols.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301

Title: CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.

Journal: British journal of pharmacology 20090301

Title: [Postoperative analgesia with fentanyl combined with flurbiprofen axetil following gynecologic surgery for turnor].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090201

Title: [In vitro effects of a novel class of nitric oxide donating compounds on isolated human urinary bladder].

Journal: Georgian medical news 20090201

Title: Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid.

Journal: Aging 20090201

Title: The nitrosylated flurbiprofen derivative HCT1026 inhibits cytokine-induced signalling through a novel mechanism of action.

Journal: European journal of pharmacology 20090114

Title: Myocarditis due to oral flurbiprofen use.

Journal: The American journal of emergency medicine 20090101

Title: Possibility of topical antioxidant treatment of cataracts: corneal penetration of pyruvate in humans.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20090101

Title: Intravitreal toxicity of ketorolac tris salt and flurbiprofen.

Journal: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20090101

Title: Recent developments in Alzheimer's disease therapeutics.

Journal: BMC medicine 20090101

Title: Adipic acid dihydrazide treated partially oxidized alginate beads for sustained oral delivery of flurbiprofen.

Journal: Pharmaceutical development and technology 20090101

Title: Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies.

Journal: Lipids in health and disease 20090101

Title: Intravenous flurbiprofen axetil can increase analgesic effect in refractory cancer pain.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?

Journal: The open neurology journal 20090101

Title: Clinical study on the bioequivalence of two tablet formulations of flurbiprofen.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development.

Journal: Current medicinal chemistry 20090101

Title: Why did tarenflurbil fail in Alzheimer's disease?

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Single dose oral flurbiprofen for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews 20090101

Title: Pathogenesis of tendinopathies: inflammation or degeneration?

Journal: Arthritis research & therapy 20090101

Title: Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis.

Journal: PloS one 20090101

Title: Diclofenac prevents temporal increase of intraocular pressure after uneventful cataract surgery with longer operation time.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Treatment of cystoid macular edema with the new-generation NSAID nepafenac 0.1%.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Management of ocular inflammation and pain following cataract surgery: focus on bromfenac ophthalmic solution.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Inhibition of surgically induced miosis and prevention of postoperative macular edema with nepafenac.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20090101

Title: Association between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgery.

Journal: PloS one 20090101

Title: Pharmacokinetics and tolerance study of intravitreal injection of dexamethasone-loaded nanoparticles in rabbits.

Journal: International journal of nanomedicine 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Subpopulations of neurons in visual area v2 perform differentiation and integration operations in space and time.

Journal: Frontiers in systems neuroscience 20090101

Title: Amitriptyline for pain control in scleritis may help to avoid excessive steroid use in selected cases: a case report.

Journal: Cases journal 20090101

Title: Efficacy of epicutaneous Diractin (ketoprofen in Transfersome gel) for the treatment of pain related to eccentric muscle contractions.

Journal: Drug design, development and therapy 20090101

Title: Postoperative analgesic effect of preoperative intravenous flurbiprofen in arthroscopic rotator cuff repair.

Journal: Journal of anesthesia 20090101

Title: Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio.

Journal: PloS one 20090101

Title: Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers.

Journal: BMC clinical pharmacology 20090101

Title: Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial.

Journal: Arthritis research & therapy 20090101

Title: Identification of human UDP-glucuronosyltransferase isoforms responsible for the glucuronidation of glycyrrhetinic acid.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Topical delivery of flurbiprofen from pluronic lecithin organogel.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Solid lipid nanoparticles: a modern formulation approach in drug delivery system.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Stabilization of quinapril by incorporating hydrogen bonding interactions.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Safety, efficacy and patient acceptability of the contraceptive and non-contraceptive uses of the LNG-IUS.

Journal: International journal of women's health 20090101

Title: Etiology and treatment of the inflammatory causes of cystoid macular edema.

Journal: Journal of inflammation research 20090101

Title: Therapeutic time window of flurbiprofen axetil's neuroprotective effect in a rat model of transient focal cerebral ischemia.

Journal: Chinese medical journal 20081220

Title: 1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: synthesis and preliminary evaluation of biological properties.

Journal: European journal of medicinal chemistry 20081201

Title: PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions.

Journal: Journal of pharmaceutical sciences 20081201

Title: The HSA affinity of warfarin and flurbiprofen determined by fluorescence anisotropy measurements of camptothecin.

Journal: Bio Systems 20081201

Title: Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.

Journal: Mechanisms of ageing and development 20081201

Title: Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides.

Journal: Experimental eye research 20081201

Title: Nanocomposites of 2-arylpropionic acid drugs based on Mg-Al layered double hydroxide for dissolution enhancement.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115

Title: Functional analysis of phenylalanine residues in the active site of cytochrome P450 2C9.

Journal: Biochemistry 20081111

Title: Photocrosslinkable starch-based polymers for ophthalmologic drug delivery.

Journal: International journal of biological macromolecules 20081101

Title: Tarenflurbil protection from cytotoxicity is associated with an upregulation of neurotrophins.

Journal: Journal of Alzheimer's disease : JAD 20081101

Title: The effects of etodolac, nimesulid and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery.

Journal: Yonsei medical journal 20081031

Title: Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid.

Journal: European journal of medicinal chemistry 20081001

Title: Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.

Journal: Aging cell 20081001

Title: Safety and clinical responses in ankylosing spondylitis after three months of etanercept therapy.

Journal: Journal of Korean medical science 20081001

Title: Dihydrotanshinone, a lipophilic component of Salvia miltiorrhiza (danshen), relaxes rat coronary artery by inhibition of calcium channels.

Journal: Journal of ethnopharmacology 20080926

Title: Chiral ionic liquids for enantioseparation of pharmaceutical products by capillary electrophoresis.

Journal: Journal of chromatography. A 20080919

Title: Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative.

Journal: Journal of chromatography. A 20080919

Title: Determining binding sites of drugs on human serum albumin using FIA-QCM.

Journal: Biosensors & bioelectronics 20080915

Title: Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes.

Journal: International journal of pharmaceutics 20080901

Title: Improvement in bioavailability of transdermally applied flurbiprofen using tulsi (Ocimum sanctum) and turpentine oil.

Journal: Colloids and surfaces. B, Biointerfaces 20080901

Title: In vitro evaluation of proniosomes as a drug carrier for flurbiprofen.

Journal: AAPS PharmSciTech 20080901

Title: Improvement of dissolution property of poorly water-soluble drug by novel dry coating method using planetary ball mill.

Journal: Chemical & pharmaceutical bulletin 20080901

Title: Effect of pH and formulation variables on in vitro transcorneal permeability of flurbiprofen: a technical note.

Journal: AAPS PharmSciTech 20080901

Title: Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis.

Journal: Electrophoresis 20080901

Title: Alpha-methylprednisolone conjugated cyclodextrin polymer-based nanoparticles for rheumatoid arthritis therapy.

Journal: International journal of nanomedicine 20080901

Title: Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples.

Journal: Journal of chromatography. A 20080815

Title: Present and prospective clinical therapeutic regimens for Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20080801

Title: The effects of topical (gel) astemizole and terfenadine on wound healing.

Journal: Indian journal of pharmacology 20080801

Title: Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone.

Journal: Archives of biochemistry and biophysics 20080715

Title: Characterization of the drug binding specificity of rat liver fatty acid binding protein.

Journal: Journal of medicinal chemistry 20080710

Title: Species differences in inhibition potential of nonsteroidal anti-inflammatory drugs against estradiol 3beta-glucuronidation between rats, dogs, and humans.

Journal: Journal of pharmaceutical sciences 20080701

Title: Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions.

Journal: Proteins 20080701

Title: [Acute renal insufficiency after flurbiprofen treatment in a patient treated with angiotensin converting enzyme inhibitor].

Journal: La Revue de medecine interne 20080701

Title: Differential genotype dependent inhibition of CYP2C9 in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: Addition of nitric oxide through nitric oxide-paracetamol enhances healing rat achilles tendon.

Journal: Clinical orthopaedics and related research 20080701

Title: Intravenous flurbiprofen axetil accelerates restoration of bowel function after colorectal surgery.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20080701

Title: Wet process-induced phase-transited drug delivery system: a means for achieving osmotic, controlled, and level A IVIVC for poorly water-soluble drug.

Journal: Drug development and industrial pharmacy 20080701

Title: Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment.

Journal: International journal of pharmaceutics 20080624

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Thermodynamic studies of Fenbufen, Diflunisal, and Flurbiprofen: sublimation, solution and solvation of biphenyl substituted drugs.

Journal: International journal of pharmaceutics 20080605

Title: Topical ocular delivery of NSAIDs.

Journal: The AAPS journal 20080601

Title: Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial.

Journal: The Lancet. Neurology 20080601

Title: Tarenflurbil: a shot on goal.

Journal: The Lancet. Neurology 20080601

Title: Cloud point extraction-HPLC method for determination and pharmacokinetic study of flurbiprofen in rat plasma after oral and transdermal administration.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080601

Title: The therapeutic effects of Rho-ROCK inhibitors on CNS disorders.

Journal: Therapeutics and clinical risk management 20080601

Title: Topical ophthalmic NSAIDs: a discussion with focus on nepafenac ophthalmic suspension.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: Rheological and functional characterization of new antiinflammatory delivery systems designed for buccal administration.

Journal: International journal of pharmaceutics 20080522

Title: Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheres.

Journal: Journal of microencapsulation 20080501

Title: Optimizing delivery of flurbiprofen to the colon using a targeted prodrug approach.

Journal: The Journal of pharmacy and pharmacology 20080501

Title: Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20080414

Title: Impregnation of an intraocular lens for ophthalmic drug delivery.

Journal: Current drug delivery 20080401

Title: Osmotically regulated flow of flurbiprofen through in situ formed asymmetric membrane capsule.

Journal: Current drug delivery 20080401

Title: Investigation of nanostructured lipid carriers for transdermal delivery of flurbiprofen.

Journal: Drug development and industrial pharmacy 20080401

Title: [Application of flurbiprofen preemptive analgesia combined with intravenous propofol anesthesia in induced abortion].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080401

Title: Transient absorption spectroscopy for determining multiple site occupancy in drug-protein conjugates. A comparison between human and bovine serum albumins using flurbiprofen methyl ester as a probe.

Journal: The journal of physical chemistry. B 20080306

Title: Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro.

Journal: Neuropharmacology 20080301

Title: Assessment of drug release from oil depot formulations using an in vitro model -- potential applicability in accelerated release testing.

Journal: Drug development and industrial pharmacy 20080301

Title: Development of enteric coated flurbiprofen tablets using Opadry/Acryl-Eze system--a technical note.

Journal: AAPS PharmSciTech 20080301

Title: Taking the next steps in the treatment of Alzheimer's disease: disease-modifying agents.

Journal: CNS spectrums 20080301

Title: Prediction of metabolism by cytochrome P450 2C9: alignment and docking studies of a validated database of substrates.

Journal: Journal of medicinal chemistry 20080227

Title: A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro.

Journal: Cancer chemotherapy and pharmacology 20080201

Title: Celecoxib inhibits proliferation of retinal pigment epithelial and choroid-retinal endothelial cells by a cyclooxygenase-2-independent mechanism.

Journal: The Journal of pharmacology and experimental therapeutics 20080201

Title: Modulatory effect of chiral nonsteroidal anti-inflammatory drugs on apoptosis of human neutrophils.

Journal: Chirality 20080201

Title: Synthesis and pharmacological evaluation of pyrazoline derivatives as new anti-inflammatory and analgesic agents.

Journal: Bioorganic & medicinal chemistry letters 20080201

Title: Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

Journal: European journal of clinical pharmacology 20080201

Title: Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080201

Title: Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study.

Journal: Clinical therapeutics 20080201

Title: Celecoxib transiently inhibits cellular protein synthesis.

Journal: Biochemical pharmacology 20080115

Title: Mechanisms of the dilator action of cryptotanshinone on rat coronary artery.

Journal: European journal of pharmacology 20080114

Title: Prejunctional inhibitory effects of isoprostanes on dopaminergic neurotransmission in bovine retinae, in vitro.

Journal: Neurochemical research 20080101

Title: In vivo methods for the assessment of topical drug bioavailability.

Journal: Pharmaceutical research 20080101

Title: Flurbiprofen derivatives in Alzheimer's disease: synthesis, pharmacokinetic and biological assessment of lipoamino acid prodrugs.

Journal: Bioconjugate chemistry 20080101

Title: Dosage plan of a flurbiprofen injection product using inhibition of protein binding by lipid emulsion in rats.

Journal: The Journal of pharmacy and pharmacology 20080101

Title: [In-vitro evaluation of cinnarizine as a competing agent to beta-cyclodextrin inclusion complexes: effect of cinnarizine on the membrane permeation rate of progesterone from its beta-cyclodextrin inclusion complex].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101

Title: Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas.

Journal: Cerebrospinal fluid research 20080101

Title: Formulation and evaluation of flurbiprofen microemulsion.

Journal: Current drug delivery 20080101

Title: Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model.

Journal: BMC musculoskeletal disorders 20080101

Title: Confirmatory identification of sixteen non-steroidal anti-inflammatory drug residues in raw milk by liquid chromatography coupled with ion trap mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20080101

Title: Transconjunctival orbital emphysema caused by compressed air injury: a case report.

Journal: Indian journal of ophthalmology 20080101

Title: Regulation of Glial Cell Functions by PPAR-gamma Natural and Synthetic Agonists.

Journal: PPAR research 20080101

Title: Straw blood cell count, growth, inhibition and comparison to apoptotic bodies.

Journal: BMC cell biology 20080101

Title: Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability.

Journal: Journal of translational medicine 20080101

Title: Interactions between APP secretases and inflammatory mediators.

Journal: Journal of neuroinflammation 20080101

Title: PPAR-gamma: Therapeutic Potential for Multiple Sclerosis.

Journal: PPAR research 20080101

Title: PPARs in Alzheimer's Disease.

Journal: PPAR research 20080101

Title: Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs.

Journal: PloS one 20080101

Title: Efficacy of intraoperative vancomycin in irrigating solutions on aqueous contamination during phacoemulsification.

Journal: Indian journal of ophthalmology 20080101

Title: Acquired Brown's syndrome associated with preseptal cellulitis.

Journal: Strabismus 20080101

Title: Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.

Journal: Molecular brain 20080101

Title: Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis.

Journal: Arthritis research & therapy 20080101

Title: Role of nitric oxide in the gastrointestinal tract.

Journal: Arthritis research & therapy 20080101

Title: Inflammaging as a prodrome to Alzheimer's disease.

Journal: Journal of neuroinflammation 20080101

Title: Cyclooxygenase inhibitors: a novel direction for Alzheimer's management.

Journal: Pharmacological reports : PR 20080101

Title: A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases: a literature review.

Journal: The open dentistry journal 20080101

Title: Surgical results of triamcinolone assisted pars plana vitrectomy combined with phacoemulsification in diabetic patients.

Journal: The open ophthalmology journal 20080101

Title: Transcorneal permeation in a corneal device of non-steroidal anti-inflammatory drugs in drug delivery systems.

Journal: The open medicinal chemistry journal 20080101

Title: A Study on Improvement of Solubility of Rofecoxib and its effect on Permeation of Drug from Topical Formulations.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Diclofenac patches for postoperative shoulder pain.

Journal: International journal of shoulder surgery 20080101

Title: In situ formed phase transited drug delivery system of ketoprofen for achieving osmotic, controlled and level a in vitro in vivo correlation.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites.

Journal: European journal of pharmacology 20071222

Title: Involvement of organic anion transport system in transdermal absorption of flurbiprofen.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20071204

Title: 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.

Journal: The Journal of pharmacology and experimental therapeutics 20071201

Title: The p38 MAPK pathway mediates aryl propionic acid induced messenger rna stability of p75 NTR in prostate cancer cells.

Journal: Cancer research 20071201

Title: Preoperative flurbiprofen for pain prevention after tonsillectomy in adults.

Journal: Journal of clinical anesthesia 20071201

Title: Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.

Journal: Current neuropharmacology 20071201

Title: Analgesic and anti-inflammatory effectiveness of nepafenac 0.1% for cataract surgery.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20071201

Title: The thermodynamic dissociation constants of four non-steroidal anti-inflammatory drugs by the least-squares nonlinear regression of multiwavelength spectrophotometric pH-titration data.

Journal: Journal of pharmaceutical and biomedical analysis 20071130

Title: Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats.

Journal: Neurochemical research 20071101

Title: New form discovery for the analgesics flurbiprofen and sulindac facilitated by polymer-induced heteronucleation.

Journal: Journal of pharmaceutical sciences 20071101

Title: The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071101

Title: [Management of antiplatelet therapy: a case report].

Journal: Annales de cardiologie et d'angeiologie 20071101

Title: Analysis of skin disposition of flurbiprofen after topical application using dual agar gel discs-inserted rats.

Journal: Biological & pharmaceutical bulletin 20071101

Title: Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition.

Journal: Molecular carcinogenesis 20071001

Title: Beta-amyloid(1-42) induces a reduction in the parallel fiber responses of Purkinje cells: possible involvement of pro-inflammatory processes.

Journal: Experimental gerontology 20071001

Title: A validated method for the analysis of diltiazem in raw materials and pharmaceutical formulations by rp-HPLC.

Journal: Pakistan journal of pharmaceutical sciences 20071001

Title: Imaging the Abeta-related neurotoxicity of Alzheimer disease.

Journal: Archives of neurology 20071001

Title: [Effect of postoperative analgesia with flurbiprofen axetil and sufentanyl on metabolism of surgical patients with intestinal carcinoma].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071001

Title: Osmotic delivery of flurbiprofen through controlled porosity asymmetric membrane capsule.

Journal: Drug development and industrial pharmacy 20071001

Title: [Is withdrawal of antiplatelet therapy necessary prior to skin cancer surgery?].

Journal: Annales de dermatologie et de venereologie 20071001

Title: GCF MMP-8 levels in smokers and non-smokers with chronic periodontitis following scaling and root planing accompanied by systemic use of flurbiprofen.

Journal: Journal of periodontology 20071001

Title: Progress update: Pharmacological treatment of Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20071001

Title: The amyloid beta ion channel hypothesis of Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20071001

Title: Topical antiinflammatory activity of an innovative aqueous formulation of actichelated propolis vs two commercial propolis formulations.

Journal: Phytotherapy research : PTR 20070901

Title: Preparation and evaluation of biodegradable flubiprofen gelatin micro-spheres for intra-articular administration.

Journal: Journal of microencapsulation 20070901

Title: Mechanisms of the vasorelaxant effect of 1-hydroxy-2, 3, 5-trimethoxy-xanthone, isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery.

Journal: Life sciences 20070901

Title: Asymmetric membrane capsule for osmotic delivery of flurbiprofen.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20070901

Title: Effective virtual screening protocol for CYP2C9 ligands using a screening site constructed from flurbiprofen and S-warfarin pockets.

Journal: Journal of computer-aided molecular design 20070901

Title: Pathogenesis of Alzheimer's disease.

Journal: Clinical interventions in aging 20070901

Title: Carboxylesterase in the liver and small intestine of experimental animals and human.

Journal: Life sciences 20070823

Title: Excited-state interactions in flurbiprofen-tryptophan dyads.

Journal: The journal of physical chemistry. B 20070809

Title: Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection.

Journal: Pharmaceutical research 20070801

Title: An Aging Interventions Testing Program: study design and interim report.

Journal: Aging cell 20070801

Title: Flurbiprofen in the symptomatic management of rheumatoid arthritis: a valuable alternative.

Journal: International journal of clinical practice 20070801

Title: Cross-reaction allergic pancreatitis with ketoprofen and flurbiprofen.

Journal: Pancreas 20070801

Title: One-step preparation of drug-containing microparticles to enhance the dissolution and absorption of poorly water-soluble drugs using a 4-fluid nozzle spray drier.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20070731

Title: Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Binary polymeric blends to microencapsulate nitroflurbiprofen: physicochemical and in silico studies.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070701

Title: In vitro interaction studies of diltiazem with NSAID's using UV spectrophotometry and RP-HPLC techniques.

Journal: Pakistan journal of pharmaceutical sciences 20070701

Title: Simultaneous analysis of cytochrome P450 probes-dextromethorphan, flurbiprofen and midazolam and their major metabolites by HPLC-mass-spectrometry/fluorescence after single-step extraction from plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

Title: Electrokinetic migration of acidic drugs across a supported liquid membrane.

Journal: Journal of chromatography. A 20070608

Title: Nanoparticles in modern medicine: state of the art and future challenges.

Journal: International journal of nanomedicine 20070601

Title: Mucoadhesive bilayered tablets for buccal sustained release of flurbiprofen.

Journal: AAPS PharmSciTech 20070601

Title: R-stereopreference analysis of lipase Novozym 435 in kinetic resolution of flurbiprofen.

Journal: Chirality 20070505

Title: Identification of flurbiprofen and its photoproducts in methanol by gas chromatography-mass spectrometry.

Journal: Biomedical chromatography : BMC 20070501

Title: Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides.

Journal: Journal of neuroscience research 20070501

Title: Traditional nonsteroidal anti-inflammatory drugs and postmenopausal hormone therapy: a drug-drug interaction?

Journal: PLoS medicine 20070501

Title: Structural and functional basis of cyclooxygenase inhibition.

Journal: Journal of medicinal chemistry 20070405

Title: Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity.

Journal: British journal of clinical pharmacology 20070401

Title: In vitro and in vivo profiling of CHF5022 and CHF5074 Two beta-amyloid1-42 lowering agents.

Journal: Pharmacological research 20070401

Title: The aryl propionic acid R-flurbiprofen selectively induces p75NTR-dependent decreased survival of prostate tumor cells.

Journal: Cancer research 20070401

Title: Design and optimization of NSAID loaded nanoparticles.

Journal: Pakistan journal of pharmaceutical sciences 20070401

Title: Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib.

Journal: Molecular cancer therapeutics 20070401

Title: [A novel class of anti-inflammatory and analgesic drugs--NO-donating NSAIDs].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070401

Title: Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint.

Journal: Life sciences 20070327

Title: Use of simple docking methods to screen a virtual library for heteroactivators of cytochrome P450 2C9.

Journal: Journal of medicinal chemistry 20070322

Title: Preadministration of flurbiprofen suppresses prostaglandin production and postoperative pain in orthopedic patients undergoing tourniquet inflation.

Journal: Journal of clinical anesthesia 20070301

Title: Ternary complexes of flurbiprofen with HP-beta-CD and ethanolamines characterization and transdermal delivery.

Journal: Drug development and industrial pharmacy 20070301

Title: [Very late intrastent thrombosis--at 27 months!].

Journal: Archives des maladies du coeur et des vaisseaux 20070301

Title: Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid.

Journal: Neuroscience 20070209

Title: Factors affecting the formation of eutectic solid dispersions and their dissolution behavior.

Journal: Journal of pharmaceutical sciences 20070201

Title: Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential.

Journal: European journal of medicinal chemistry 20070201

Title: Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats.

Journal: Gastroenterology 20070201

Title: Drug evaluation: (R)-flurbiprofen--an enantiomer of flurbiprofen for the treatment of Alzheimer's disease.

Journal: IDrugs : the investigational drugs journal 20070201

Title: Flurbiprofen: new indication. Lozenges: NSAIDs are not to be taken like sweets!

Journal: Prescrire international 20070201

Title: Gingival crevicular fluid prostaglandin E(2) and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen.

Journal: Journal of periodontology 20070101

Title: Unilateral conjunctival chemosis as a unique symptom of nonsteroidal anti-inflammatory drug intolerance.

Journal: Journal of investigational allergology & clinical immunology 20070101

Title: Electrospray ionization/atmospheric pressure photoionization multimode source for low-flow liquid chromatography/mass spectrometric analysis.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Design and synthesis of some new thiazolo [3,2-b]-1,2,4-triazole-5(6H)-ones substituted with flurbiprofen as anti-inflammatory and analgesic agents.

Journal: Arzneimittel-Forschung 20070101

Title: Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer.

Journal: Breast cancer research : BCR 20070101

Title: Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.

Journal: BMC neuroscience 20070101

Title: Emulsion of flurbiprofen axetil reduces propofol injection pain due to a decrease in free propofol concentration.

Journal: Journal of anesthesia 20070101

Title: Exploring effects of different nonsteroidal antiinflammatory drugs on lipid peroxidation. Part II. 4-HNE profile.

Journal: Acta poloniae pharmaceutica 20070101

Title: Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells.

Journal: Photochemistry and photobiology 20070101

Title: Functional evolution of the vitamin D and pregnane X receptors.

Journal: BMC evolutionary biology 20070101

Title: Molecular cloning and functional expression of esf gene encoding enantioselective lipase from Serratia marcescens ES-2 for kinetic resolution of optically active (S)-flurbiprofen.

Journal: Journal of microbiology and biotechnology 20070101

Title: Bortezomib in combination with celecoxib in patients with advanced solid tumors: a phase I trial.

Journal: BMC cancer 20070101

Title: Safety, tolerability, pharmacokinetics, and Abeta levels after short-term administration of R-flurbiprofen in healthy elderly individuals.

Journal: Alzheimer disease and associated disorders 20070101

Title: A tale of switched functions: from cyclooxygenase inhibition to M-channel modulation in new diphenylamine derivatives.

Journal: PloS one 20070101

Title: Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A.

Journal: Analytical chemistry 20061215

Title: CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201

Title: Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase.

Journal: Biochemical pharmacology 20061115

Title: Flurbiprofen loaded biodegradable nanoparticles for ophtalmic administration.

Journal: Journal of pharmaceutical sciences 20061101

Title: Flurbiprofen and its nitric oxide-releasing derivative protect against septic shock in rats.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061101

Title: Synthesis and pharmacological evaluation of some dual-acting amino-alcohol ester derivatives of flurbiprofen and 2-[1,1'-biphenyl-4-yl]acetic acid: a potential approach to reduce local gastrointestinal toxicity.

Journal: Chemistry & biodiversity 20061101

Title: Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001

Title: [Clinical observation of propofol combined with flurbiprofen axetil for induced abortion anesthesia].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001

Title: Phacoemulsification and acryl foldable intraocular lens implantation in dogs: 32 cases.

Journal: Journal of veterinary science 20060901

Title: Use of triplet excited States for the study of drug binding to human and bovine serum albumins.

Journal: ChemMedChem 20060901

Title: Molecular properties of flurbiprofen and its solid dispersions with Eudragit RL100 studied by high- and low-resolution solid-state nuclear magnetic resonance.

Journal: Pharmaceutical research 20060901

Title: Validation of incorporating flurbiprofen into the Pittsburgh cocktail.

Journal: Clinical pharmacology and therapeutics 20060901

Title: Osmotic flow through asymmetric membrane: a means for controlled delivery of drugs with varying solubility.

Journal: AAPS PharmSciTech 20060901

Title: Prophylaxis of migraine.

Journal: Neuropsychiatric disease and treatment 20060901

Title: Design and evaluation of colon specific drug delivery system containing flurbiprofen microsponges.

Journal: International journal of pharmaceutics 20060802

Title: Vancomycin as chiral selector for enantioselective separation of selected profen nonsteroidal anti-inflammatory drugs in capillary liquid chromatography.

Journal: Chirality 20060801

Title: Antioxidant activity and inhibition of human neutrophil oxidative burst mediated by arylpropionic acid non-steroidal anti-inflammatory drugs.

Journal: Biological & pharmaceutical bulletin 20060801

Title: Influence of age on flurbiprofen axetil requirements for preventing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, vehicle-controlled, parallel-group, dose-ranging study.

Journal: Clinical therapeutics 20060801

Title: Prevention of corneal neovascularization: evaluation of various commercially available compounds in an experimental rat model.

Journal: Cornea 20060801

Title: Study on the mechanism of photosensitive dermatitis caused by ketoprofen in the guinea pig.

Journal: Archives of toxicology 20060701

Title: Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons.

Journal: Neurobiology of disease 20060701

Title: Pharmacokinetic parameters of (R)-(-) and (S)-(+)-flurbiprofen in dairy bovines.

Journal: Veterinary research communications 20060701

Title: Chamazulene carboxylic acid and matricin: a natural profen and its natural prodrug, identified through similarity to synthetic drug substances.

Journal: Journal of natural products 20060701

Title: In vitro interactions of captopril with NSAID's.

Journal: Pakistan journal of pharmaceutical sciences 20060701

Title: Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.

Journal: Digestive diseases and sciences 20060701

Title: Determination of ibuprofen and flurbiprofen in pharmaceuticals by capillary zone electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20060616

Title: Anti-inflammatory agents in the management of alimentary mucositis.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060601

Title: In vivo and in vitro evaluation of essential oils from Ligusticum chuanxiong Hort on the transdermal delivery of flurbiprofen in rabbits.

Journal: Biological & pharmaceutical bulletin 20060601

Title: The effect of combinations of flurbiprofen, low molecular weight heparin, and doxycycline on the inhibition of corneal neovascularization.

Journal: Cornea 20060601

Title: In vitro metabolism of (nitrooxy)butyl ester nitric oxide-releasing compounds: comparison with glyceryl trinitrate.

Journal: The Journal of pharmacology and experimental therapeutics 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin.

Journal: Pharmaceutical research 20060501

Title: Improving the diagnosis and treatment of Alzheimer's disease.

Journal: Medicine and health, Rhode Island 20060501

Title: The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.

Journal: Bioorganic & medicinal chemistry letters 20060415

Title: Mechanisms of the vasorelaxant effect of Danshen (Salvia miltiorrhiza) in rat knee joints.

Journal: Journal of ethnopharmacology 20060406

Title: Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases.

Journal: Neurobiology of disease 20060401

Title: Proton sensitivity Ca2+ permeability and molecular basis of acid-sensing ion channels expressed in glabrous and hairy skin afferents.

Journal: Journal of neurophysiology 20060401

Title: Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat.

Journal: British journal of pharmacology 20060401

Title: Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes.

Journal: BJU international 20060401

Title: Controlled porosity osmotic pump for the delivery of flurbiprofen.

Journal: Current drug delivery 20060401

Title: An epidural initial dose is unnecessary in combined spinal epidural anesthesia for Caesarean section.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20060401

Title: Comparison of the percutaneous absorption of hydrophilic and lipophilic compounds in shed snake skin and human skin.

Journal: Die Pharmazie 20060401

Title: [On the new guidelines for inhibitors of hemostasis and regional neuraxial anesthesia].

Journal: Revista espanola de anestesiologia y reanimacion 20060301

Title: Characterization of the transdermal transport of flurbiprofen and indomethacin.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060221

Title: Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate.

Journal: Journal of clinical pharmacology 20060201

Title: Dual effect of flurbiprofen on cell proliferation and agonist-induced Ca(2+) movement in human osteosarcoma cells.

Journal: Basic & clinical pharmacology & toxicology 20060201

Title: Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer.

Journal: Cancer research 20060201

Title: Drug nanoparticle formation from drug/HPMC/SDS ternary ground mixtures.

Journal: Die Pharmazie 20060201

Title: Preparation of submicron unilamellar liposomes by freeze-drying double emulsions.

Journal: Biochimica et biophysica acta 20060201

Title: Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies.

Journal: Clinical pharmacology and therapeutics 20060101

Title: Preparation and characterization of poly(D,L-lactic-co-glycolic Acid) microspheres containing flurbiprofen sodium.

Journal: Drug delivery 20060101

Title: Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery.

Journal: Journal of anesthesia 20060101

Title: Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.

Journal: Molecular cancer 20060101

Title: Dyspnea assessment and adverse events during sputum induction in COPD.

Journal: BMC pulmonary medicine 20060101

Title: Pathological and physiological functions of presenilins.

Journal: Molecular neurodegeneration 20060101

Title: Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics.

Journal: Journal of biomedicine & biotechnology 20060101

Title: Determination of fourteen non-steroidal anti-inflammatory drugs in animal serum and plasma by liquid chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Atypical cytochrome p450 kinetics: implications for drug discovery.

Journal: Drugs in R&D 20060101

Title: The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease.

Journal: Journal of neuroinflammation 20060101

Title: Multi-residue determination of non-steroidal anti-inflammatory drug residues in animal serum and plasma by HPLC and photo-diode array detection.

Journal: Journal of chromatographic science 20060101

Title: Exploring effects of different nonsteroidal antiinflammatory drugs on malondialdehyde profile.

Journal: Acta poloniae pharmaceutica 20060101

Title: Non-steroidal anti-inflammatory drugs have anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro.

Journal: Neuropharmacology 20051201

Title: Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease.

Journal: PLoS medicine 20051201

Title: Anterior scleritis, scleral thinning, and intraocular pressure measurement.

Journal: Ocular immunology and inflammation 20051201

Title: 'In vitro' differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology.

Journal: Inflammation 20051201

Title: Transmural gradient of leukocyte-endothelial interaction in the rat gastrointestinal tract.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20051101

Title: Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same?

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: The unexpected side effects of new nonsteroidal anti-inflammatory drugs.

Journal: Expert opinion on emerging drugs 20051101

Title: Preparation of two-drug composite microparticles to improve the dissolution of insoluble drug in water for use with a 4-fluid nozzle spray drier.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051020

Title: Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001

Title: Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.

Journal: Journal of medicinal chemistry 20050908

Title: Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells.

Journal: Carcinogenesis 20050901

Title: CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.

Journal: Molecular pharmacology 20050901

Title: Mechanisms of the dilator action of Danshen (Salvia miltiorrhiza) on rat isolated femoral artery.

Journal: Journal of cardiovascular pharmacology 20050901

Title: Poly(amidoamine) (PAMAM) dendritic nanostructures for controlled site-specific delivery of acidic anti-inflammatory active ingredient.

Journal: AAPS PharmSciTech 20050901

Title: Effects of non-ionic surfactants on isotachophoretic separations of 2-arylpropionic acids.

Journal: Journal of chromatography. A 20050819

Title: Experimental optimization of enzymic kinetic resolution of racemic flurbiprofen.

Journal: Biotechnology and applied biochemistry 20050801

Title: Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Title: Flurbiprofen and HCT1026 protect mice against acute pancreatitis-associated lung injury.

Journal: Shock (Augusta, Ga.) 20050801

Title: Effect of pore size of FSM-16 on the entrapment of flurbiprofen in mesoporous structures.

Journal: Chemical & pharmaceutical bulletin 20050801

Title: Involvement of endothelial cyclo-oxygenase metabolites in noradrenaline-induced contraction of rat coronary artery.

Journal: Clinical and experimental pharmacology & physiology 20050801

Title: Development of fast-dissolving tablets of flurbiprofen-cyclodextrin complexes.

Journal: Drug development and industrial pharmacy 20050801

Title: Triplet excited States as chiral reporters for the binding of drugs to transport proteins.

Journal: Journal of the American Chemical Society 20050727

Title: Encapsulation efficiency of water-soluble and insoluble drugs in liposomes prepared by the microencapsulation vesicle method.

Journal: International journal of pharmaceutics 20050714

Title: Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701

Title: Incidence of mucocutaneous reactions in children treated with niflumic acid, other nonsteroidal antiinflammatory drugs, or nonopioid analgesics.

Journal: Pediatrics 20050701

Title: Evaluation of a local anaesthesia regimen using a subphrenic catheter after gynaecological laparoscopy.

Journal: European journal of anaesthesiology 20050601

Title: Reversal of elution order for profen acid enantiomers in packed-column SFC on Chiralpak AD.

Journal: Chirality 20050515

Title: Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

Journal: Journal of medicinal chemistry 20050505

Title: Flurbiprofen axetil preceded by venous occlusion in the prevention of pain on propofol injection in the hand: a prospective, randomized, double-blind, vehicle-controlled, dose-finding study in Japanese adult surgical patients.

Journal: Clinical therapeutics 20050501

Title: Dissolution, solubility, XRD, and DSC studies on flurbiprofen-nicotinamide solid dispersions.

Journal: Drug development and industrial pharmacy 20050501

Title: Development and validation of HPLC method for determination of indomethacin and its two degradation products in topical gel.

Journal: Journal of pharmaceutical and biomedical analysis 20050429

Title: Determination of stability constant values of flurbiprofen-cyclodextrin complexes using different techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20050429

Title: Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.

Journal: Journal of medicinal chemistry 20050407

Title: A combined first principles computational and solid-state NMR study of a molecular crystal: flurbiprofen.

Journal: Physical chemistry chemical physics : PCCP 20050407

Title: UDP-glucuronosyltransferases and clinical drug-drug interactions.

Journal: Pharmacology & therapeutics 20050401

Title: Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology.

Journal: Brain research. Brain research reviews 20050401

Title: Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease.

Journal: Brain research. Brain research reviews 20050401

Title: Preparation and in vitro characterization of a semi-solid dispersion of flurbiprofen with Gelucire 44/14 and Labrasol.

Journal: Die Pharmazie 20050401

Title: Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53.

Journal: Biochemical pharmacology 20050301

Title: Cytochrome P-450 activity is differentially altered in severely injured patients.

Journal: Critical care medicine 20050301

Title: Synthesis of some new 2-(2-fluoro-4-biphenylyl)propionic acid derivatives as potential anti-inflammatory agents.

Journal: Die Pharmazie 20050301

Title: Pain control during fixed orthodontic appliance therapy.

Journal: The Angle orthodontist 20050301

Title: Ocular pharmacology of bicyclic hexahydroaporphines.

Journal: Methods and findings in experimental and clinical pharmacology 20050301

Title: Perioperative sonoclot analysis in patients given flurbiprofen.

Journal: European journal of anaesthesiology 20050301

Title: Molecule of the month. MPC-7869 (Flurizan).

Journal: Drug news & perspectives 20050301

Title: The addition of epidural morphine to ropivacaine improves epidural analgesia after lower abdominal surgery.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050201

Title: Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen.

Journal: Journal of neurochemistry 20050201

Title: The effect of systemic administration of ibuprofen in the experimental gingivitis model.

Journal: Journal of clinical periodontology 20050201

Title: Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases.

Journal: Electrophoresis 20050201

Title: Pharmacokinetics and synovial fluid concentrations of flurbiprofen enantiomers in horses: chiral inversion.

Journal: Journal of veterinary pharmacology and therapeutics 20050201

Title: NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.

Journal: European journal of pharmacology 20050131

Title: Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions.

Journal: International journal of pharmaceutics 20050106

Title: Lack of specific amyloid-beta(1-42) suppression by nonsteroidal anti-inflammatory drugs in young, plaque-free Tg2576 mice and in guinea pig neuronal cultures.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: Clinical effects of flurbiprofen tooth patch on radiation-induced oral mucositis. A pilot study.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20050101

Title: Changes in mechanical, chemical, and thermal sensitivity of the cornea after topical application of nonsteroidal anti-inflammatory drugs.

Journal: Investigative ophthalmology & visual science 20050101

Title: Dual effect of isoprostanes on the release of [3H]D-aspartate from isolated bovine retinae: role of arachidonic acid metabolites.

Journal: Neurochemical research 20050101

Title: Effect of nonsteroidal anti-inflammatory drugs with varying extent of COX-2-COX-1 selectivity on urinary sodium and potassium excretion in the rat.

Journal: Canadian journal of physiology and pharmacology 20050101

Title: Study of the percutaneous penetration of flurbiprofen by cutaneous and subcutaneous microdialysis after iontophoretic delivery in rat.

Journal: Journal of pharmaceutical sciences 20050101

Title: Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines.

Journal: BMC pharmacology 20050101

Title: Formulation studies and in vivo evaluation of a flurbiprofen-hydroxypropyl beta-cyclodextrin system.

Journal: Pharmaceutical development and technology 20050101

Title: Sample pretreatment and determination of non steroidal anti-inflammatory drugs (NSAIDs) in pharmaceutical formulations and biological samples (blood, plasma, erythrocytes) by HPLC-UV-MS and micro-HPLC.

Journal: Current medicinal chemistry 20050101

Title: [Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain].

Journal: Terapevticheskii arkhiv 20050101

Title: The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases.

Journal: Current pharmaceutical design 20050101

Title: Pain management after lumbar spinal fusion surgery using continuous subcutaneous infusion of buprenorphine.

Journal: Journal of anesthesia 20050101

Title: Solid lipid nanoparticles bearing flurbiprofen for transdermal delivery.

Journal: Drug delivery 20050101

Title: Transdermal delivery of flurbiprofen: permeation enhancement, design, pharmacokinetic, and pharmacodynamic studies in albino rats.

Journal: Pharmaceutical development and technology 20050101

Title: Treatment of pseudophakic cystoid macular oedema.

Journal: Collegium antropologicum 20050101

Title: How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen.

Journal: Journal of anesthesia 20050101

Title: Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery.

Journal: Head & face medicine 20050101

Title: Long-term use of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population.

Journal: BMC medicine 20050101

Title: Adjuvant arthritis-induced changes on ampicillin binding in serum and tissues under the influence of non-steroidal anti-inflammatory drugs in rats.

Journal: European journal of drug metabolism and pharmacokinetics 20050101

Title: Analgesic effect of sustained-release flurbiprofen administered at the site of tissue injury in the oral surgery model.

Journal: Journal of clinical pharmacology 20041201

Title: Pretreatment with flurbiprofen axetil and venous occlusion to reduce pain during injection of propofol.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20041201

Title: Enantioseparation of flurbiprofen and ketoprofen in patches and in urine excretions by achiral gas chromatography.

Journal: Archives of pharmacal research 20041201

Title: The cyclooxygenase inhibitor flurbiprofen reduces radiation-induced angiogenic growth factor secretion of squamous cell carcinoma cell lines.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Excised porcine skin experimental systems to validate quantitative microdialysis methods for determination of drugs in skin after topical application.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20041124

Title: A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20041101

Title: Calculation of cyclodextrin binding affinities: energy, entropy, and implications for drug design.

Journal: Biophysical journal 20041101

Title: Evaluation of the bioavailability of flurbiprofen and its beta-cyclodextrin inclusion complex in four different doses upon oral administration to rats.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20041101

Title: Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action.

Journal: Journal of neurochemistry 20041101

Title: The potential role of non-steroidal anti-inflammatory drugs in treating Alzheimer's disease.

Journal: Expert opinion on investigational drugs 20041101

Title: Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis.

Journal: Journal of computer-aided molecular design 20041101

Title: Selected non-steroidal anti-inflammatory drugs and their derivatives target gamma-secretase at a novel site. Evidence for an allosteric mechanism.

Journal: The Journal of biological chemistry 20041015

Title: The effects and metabolic fate of nitroflurbiprofen in healthy volunteers.

Journal: Clinical pharmacology and therapeutics 20041001

Title: Interactions between aspirin and COX-2 inhibitors or NSAIDs in a rat thrombosis model.

Journal: Fundamental & clinical pharmacology 20041001

Title: A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes.

Journal: Journal of pharmaceutical and biomedical analysis 20040903

Title: Cationic vesicles as chiral selector for enantioseparations of nonsteroidal antiinflammatory drugs by micellar electrokinetic chromatography.

Journal: Journal of chromatography. A 20040903

Title: The flurbiprofen derivatives HCT1026 and HCT1027 inhibit bone resorption by a mechanism independent of COX inhibition and nitric oxide production.

Journal: Bone 20040901

Title: Effect of camellia oil on the permeation of flurbiprofen and diclofenac sodium through rat and pig skin.

Journal: Biological & pharmaceutical bulletin 20040901

Title: The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution.

Journal: The Journal of biological chemistry 20040820

Title: Risk of breast cancer among users of aspirin and other anti-inflammatory drugs.

Journal: British journal of cancer 20040802

Title: Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation.

Journal: The Journal of biological chemistry 20040702

Title: Bioinversion of R-flurbiprofen to S-flurbiprofen at various dose levels in rat, mouse, and monkey.

Journal: Chirality 20040701

Title: S- but not R-enantiomers of flurbiprofen and ibuprofen reduce human microglial and THP-1 cell neurotoxicity.

Journal: Journal of neuroimmunology 20040701

Title: Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe.

Journal: The Journal of endocrinology 20040701

Title: NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property?

Journal: Biochemical pharmacology 20040615

Title: Effector-mediated alteration of substrate orientation in cytochrome P450 2C9.

Journal: Biochemistry 20040608

Title: Cyclooxygenase involvement in thromboxane-dependent contraction in rat mesenteric resistance arteries.

Journal: Hypertension (Dallas, Tex. : 1979) 20040601

Title: Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration.

Journal: Pharmacotherapy 20040601

Title: Influence of preparation methodology on solid-state properties of an acidic drug-cyclodextrin system.

Journal: The Journal of pharmacy and pharmacology 20040601

Title: HPLC microdetermination of flurbiprofen enantiomers in plasma with a glycopeptide-type chiral stationary phase column.

Journal: Biomedical chromatography : BMC 20040601

Title: A rabbit ear flap perfusion experiment to evaluate the percutaneous absorption of drugs.

Journal: International journal of pharmaceutics 20040519

Title: Fatty acids in Botryococcus braunii accelerate topical delivery of flurbiprofen into and across skin.

Journal: International journal of pharmaceutics 20040519

Title: Differential activation of CYP2C9 variants by dapsone.

Journal: Biochemical pharmacology 20040515

Title: Responsiveness of C-fiber nociceptors to punctate force-controlled stimuli in isolated rat skin: lack of modulation by inflammatory mediators and flurbiprofen.

Journal: Neuroscience letters 20040506

Title: Enantioseparation of hydrochloride salts using carbon dioxide-based mobile phases with on-line polarimetric detection.

Journal: Chirality 20040505

Title: Gastric tolerability and prolonged prostaglandin inhibition in the brain with a nitric oxide-releasing flurbiprofen derivative, NCX-2216 [3-[4-(2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester].

Journal: The Journal of pharmacology and experimental therapeutics 20040501

Title: Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory.

Journal: American journal of physiology. Renal physiology 20040501

Title: A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis.

Journal: Journal of neuroimmunology 20040501

Title: Nitroflurbiprofen (NicOx).

Journal: Current opinion in investigational drugs (London, England : 2000) 20040501

Title: Arachidonic acid metabolites and peroxide-induced inhibition of [3H]D-aspartate release from bovine isolated retinae.

Journal: Current eye research 20040501

Title: Resolution of indobufen enantiomers by capillary zone electrophoresis. Pharmacokinetic studies of human serum.

Journal: Journal of chromatography. A 20040402

Title: Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9.

Journal: Molecular pharmacology 20040401

Title: Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care.

Journal: Fundamental & clinical pharmacology 20040401

Title: The influence on human osteoblasts in vitro of non-steroidal anti-inflammatory drugs which act on different cyclooxygenase enzymes.

Journal: The Journal of bone and joint surgery. British volume 20040401

Title: Thermodynamics of solutions III: comparison of the solvation of (+)-naproxen with other NSAIDs.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040301

Title: Acid-sensing ion channels (ASICs): new targets for the analgesic effects of non-steroid anti-inflammatory drugs (NSAIDs).

Journal: Current drug targets. Inflammation and allergy 20040301

Title: Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug.

Journal: Journal of periodontology 20040301

Title: Solvation and hydration characteristics of ibuprofen and acetylsalicylic acid.

Journal: AAPS pharmSci 20040301

Title: Manipulation of kinetic profiles in 2-aryl propionic acid cyclooxygenase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Placing bets. National Institute on Aging committee chooses three compounds for definitive longevity testing.

Journal: Science of aging knowledge environment : SAGE KE 20040204

Title: Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release.

Journal: The Journal of pharmacology and experimental therapeutics 20040201

Title: Modeling of adhesion in tablet compression. II. Compaction studies using a compaction simulator and an instrumented tablet press.

Journal: Journal of pharmaceutical sciences 20040201

Title: In vitro release and stereoselective disposition of flurbiprofen loaded to poly(D,L-lactide- co-glycolide) nanoparticles in rats.

Journal: Chirality 20040201

Title: Intravenous administration of flurbiprofen does not affect cerebral blood flow velocity and cerebral oxygenation under isoflurane and propofol anesthesia.

Journal: Anesthesia and analgesia 20040201

Title: Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration.

Journal: Neurobiology of disease 20040201

Title: Investigation of the release test method for the topical application of pharmaceutical preparations: release test of cataplasm including nonsteroidal anti-inflammatory drugs using artificial sweat.

Journal: Chemical & pharmaceutical bulletin 20040201

Title: Optimization of sample stacking for the simultaneous determination of nonsteroidal anti-inflammatory drugs with a wall-coated histidine capillary column.

Journal: Electrophoresis 20040201

Title: Possible involvement of the endocannabinoid system in the actions of three clinically used drugs.

Journal: Trends in pharmacological sciences 20040201

Title: Effect of nitric oxide releasing paracetamol and flurbiprofen on cytokine production in human blood.

Journal: European journal of pharmacology 20040112

Title: The 2.0 A resolution crystal structure of prostaglandin H2 synthase-1: structural insights into an unusual peroxidase.

Journal: Journal of molecular biology 20040109

Title: Endotoxin inhibits the surge secretion of gonadotropin-releasing hormone via a prostaglandin-independent pathway.

Journal: Endocrinology 20040101

Title: Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures.

Journal: Journal of neurochemistry 20040101

Title: Arthritis medication studied for Alzheimer's disease prevention.

Journal: Mayo Clinic women's healthsource 20040101

Title: [Safety of a novel preparation -- strepfen -- for symptomatic treatment of pain in the throat].

Journal: Vestnik otorinolaringologii 20040101

Title: Monolateral coxitis as a unique osteoarticular manifestation of Parvovirus B19 infection.

Journal: Clinical and experimental rheumatology 20040101

Title: In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome P-450-monooxygenase.

Journal: Cancer investigation 20040101

Title: Lipid nano/submicron emulsions as vehicles for topical flurbiprofen delivery.

Journal: Drug delivery 20040101

Title: Cullen frontal sinus valved glaucoma shunt: preliminary findings in dogs with primary glaucoma.

Journal: Veterinary ophthalmology 20040101

Title: Topical NSAIDs for chronic musculoskeletal pain: systematic review and meta-analysis.

Journal: BMC musculoskeletal disorders 20040101

Title: Comparison between flurbiprofen and its nitric oxide-releasing derivatives HCT-1026 and NCX-2216 on Abeta(1-42)-induced brain inflammation and neuronal damage in the rat.

Journal: International journal of immunopathology and pharmacology 20040101

Title: Characterisation of the lowest singlet and triplet excited states of S-flurbiprofen.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040101

Title: [Results of an open prospective controlled randomized comparative trial of efficacy and tolerance of sublingual tablets flurbiprofen (strepfen) and paracetamol in patients with throat pain in acute infectious-inflammatory diseases of the upper respiratory tracts].

Journal: Vestnik otorinolaringologii 20040101

Title: Reduction of Propofol-Induced Pain through Pretreatment with Lidocaine and/or Flurbiprofen.

Journal: Clinical drug investigation 20040101

Title: Thermodynamics of solutions IV: Solvation of ketoprofen in comparison with other NSAIDs.

Journal: Journal of pharmaceutical sciences 20031201

Title: Different in vitro activity of flurbiprofen and its enantiomers on human articular cartilage.

Journal: Farmaco (Societa chimica italiana : 1989) 20031201

Title: Effects of anti-inflammatory drugs on convulsant activity of quinolones: a comparative study of drug interaction between quinolones and anti-inflammatory drugs.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20031201

Title: Prednisolone and flurbiprofen drops to maintain mydriasis during phacoemulsification cataract surgery.

Journal: Journal of cataract and refractive surgery 20031201

Title: Noradrenaline-induced contraction mediated by endothelial COX-1 metabolites in the rat coronary artery.

Journal: Journal of cardiovascular pharmacology 20031201

Title: Inflammatory mediators do not stimulate CGRP release if prostaglandin synthesis is blocked by S(+)-flurbiprofen in isolated rat skin.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20031201

Title: An in vitro study of corpus cavernosum and aorta from mice lacking the inducible nitric oxide synthase gene.

Journal: Nitric oxide : biology and chemistry 20031201

Title: Contact dermatitis from peppermint and menthol in a local action transcutaneous patch.

Journal: Contact dermatitis 20031201

Title: Preparation and characterization of flurbiprofen beads by melt solidification technique.

Journal: AAPS PharmSciTech 20031201

Title: [Prescription of NSAIDs in patients treatment with platelet inhibitors or anticoagulants].

Journal: Presse medicale (Paris, France : 1983) 20031122

Title: [Comparison of analgesic effects of intravenous flurbprofen and suppository indomethacin after laparoscopic cholecystectomy].

Journal: Masui. The Japanese journal of anesthesiology 20031101

Title: P2Y2 receptor-stimulated release of prostaglandin E2 by rat inner medullary collecting duct preparations.

Journal: American journal of physiology. Renal physiology 20031001

Title: Inhibition of the rat hepatic microsomal flurbiprofen acyl glucuronidation by bile acids.

Journal: Journal of pharmaceutical sciences 20031001

Title: The comparison of efficacies of topical corticosteroids and nonsteroidal anti-inflammatory drops on dry eye patients: a clinical and immunocytochemical study.

Journal: American journal of ophthalmology 20031001

Title: 4'-hydroxylation of flurbiprofen by rat liver microsomes in fasting and feeding conditions.

Journal: Biological & pharmaceutical bulletin 20031001

Title: Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium.

Journal: Reproduction (Cambridge, England) 20031001

Title: Disposition of flurbiprofen in man: influence of stereochemistry and age.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031001

Title: Stereospecific high-performance liquid chromatographic analysis of flurbiprofen: application to pharmacokinetic studies.

Journal: Journal of pharmaceutical and biomedical analysis 20030915

Title: Capillary electrophoresis with laser induced-fluorescence detection of profens derivatized with the water-soluble fluorogenic reagent 4-N-(4-N'-aminoethyl)piperazino-7-nitro-2,1,3-benzoxadiazole.

Journal: Journal of chromatography. A 20030905

Title: Characterisation of somatostatin actions on knee joint blood vessels of the rat.

Journal: European journal of pharmacology 20030808

Title: NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.

Journal: The Journal of clinical investigation 20030801

Title: Unoprostone isopropyl ester darkens iris color in pigmented rabbits with sympathetic denervation.

Journal: Journal of glaucoma 20030801

Title: Simultaneous chiral discrimination of multiple profens by cyclodextrin-modified capillary electrophoresis in normal and reversed polarity modes.

Journal: Electrophoresis 20030801

Title: Thermodynamics of solutions. II. Flurbiprofen and diflunisal as models for studying solvation of drug substances.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030801

Title: Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: Activation of c-Jun-N-terminal-kinase is crucial for the induction of a cell cycle arrest in human colon carcinoma cells caused by flurbiprofen enantiomers.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701

Title: The influence of brain inflammation upon neuronal adenosine A2B receptors.

Journal: Journal of neurochemistry 20030701

Title: Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)-threonine-impregnated silica gel as stationary phases.

Journal: Biomedical chromatography : BMC 20030701

Title: S+ -flurbiprofen but not 5-HT1 agonists suppress basal and stimulated CGRP and PGE2 release from isolated rat dura mater.

Journal: Pain 20030601

Title: Determination of the eicosanoid response to inflammatory stimuli in whole blood and its pharmacological modulation ex vivo.

Journal: Journal of immunological methods 20030601

Title: Addition of nitric oxide via nitroflurbiprofen enhances the material properties of early healing of young rat Achilles tendons.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030601

Title: Dextrans--potential polymeric drug carriers for flurbiprofen.

Journal: Die Pharmazie 20030601

Title: Stereoselective pharmacokinetics of flurbiprofen and formation of covalent adducts with plasma protein in adjuvant-induced arthritic rats.

Journal: Chirality 20030515

Title: Solubilization of flurbiprofen in pH-surfactant solutions.

Journal: Journal of pharmaceutical sciences 20030501

Title: Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity.

Journal: The Journal of biological chemistry 20030425

Title: In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug.

Journal: International journal of pharmaceutics 20030414

Title: Modeling of adhesion in tablet compression--I. Atomic force microscopy and molecular simulation.

Journal: Journal of pharmaceutical sciences 20030401

Title: Differences in flurbiprofen pharmacokinetics between CYP2C9*1/*1, *1/*2, and *1/*3 genotypes.

Journal: European journal of clinical pharmacology 20030401

Title: Inhibition of nuclear factor-kappaB by a nitro-derivative of flurbiprofen: a possible mechanism for antiinflammatory and antiproliferative effect.

Journal: Antioxidants & redox signaling 20030401

Title: Mechanisms of vasorelaxation to testosterone in the rat aorta.

Journal: European journal of pharmacology 20030328

Title: Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase.

Journal: Journal of neuroscience research 20030315

Title: Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030301

Title: Flurbiprofen inhibits capsaicin induced calcitonin gene related peptide release from rat spinal cord via an endocannabinoid dependent mechanism.

Journal: Neuroscience letters 20030227

Title: [Diclofenac sodium or pred forte in the topical treatment of the fribrinous membrane after intraocular lens implantation in rabbits].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20030227

Title: Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations.

Journal: Archives of biochemistry and biophysics 20030201

Title: Intrathecally applied flurbiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test.

Journal: The European journal of neuroscience 20030201

Title: Acidic nonsteroidal anti-inflammatory drugs inhibit rat brain fatty acid amide hydrolase in a pH-dependent manner.

Journal: Journal of enzyme inhibition and medicinal chemistry 20030201

Title: Effect of enhancers and retarders on percutaneous absorption of flurbiprofen from hydrogels.

Journal: International journal of pharmaceutics 20030116

Title: Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030115

Title: Effect of dextran as a run buffer additive in drug-protein binding studies using capillary electrophoresis frontal analysis.

Journal: Analytical chemistry 20030115

Title: Calcium-dependent synergistic interaction of platelet activating factor and epinephrine in human platelet aggregation.

Journal: Acta pharmacologica Sinica 20030101

Title: Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans.

Journal: Journal of clinical pharmacology 20030101

Title: Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis.

Journal: Electrophoresis 20030101

Title: Topical nonsteroidal anti-inflammatory therapy in ophthalmology.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101

Title: Formulation study and anti-inflammatory efficacy of topical semi-solids containing a nitro ester of flurbiprofen.

Journal: Skin pharmacology and applied skin physiology 20030101

Title: The stereospecificity of flobufen metabolism in isolated guinea pig hepatocytes.

Journal: BMC pharmacology 20030101

Title: Tranexamic acid: a review of its use in the management of menorrhagia.

Journal: Drugs 20030101

Title: Flurbiprofen, a unique non-steroidal anti-inflammatory drug with antimicrobial activity against Trichophyton, Microsporum and Epidermophyton species.

Journal: Letters in applied microbiology 20030101

Title: Modifications of clonidine binding to rabbit liver protein under the influence of non-steroid-anti-inflammatory drugs in vitro.

Journal: European journal of drug metabolism and pharmacokinetics 20030101

Title: Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis.

Journal: BMC cancer 20030101

Title: Regulation of intraluteal production of prostaglandins.

Journal: Reproductive biology and endocrinology : RB&E 20030101

Title: Capillary electrochromatographic separation of non-steroidal anti-inflammatory drugs with a histidine bonded phase.

Journal: Journal of chromatography. A 20021227

Title: Contractile effect of anaphylatoxin C5a and of a mimetic peptide on the human umbilical artery: further evidence for leukocyte-dependent vasomotion.

Journal: Journal of cardiovascular pharmacology 20021201

Title: [The trends in new drugs for the prostate cancer].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201

Title: Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2).

Journal: Biochemistry 20021112

Title: NO-flurbiprofen maintains duodenal blood flow, enhances mucus secretion contributing to lower mucosal injury.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20021101

Title: Activation of CYP2C9-mediated metabolism by a series of dapsone analogs: kinetics and structural requirements.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021101

Title: Centrally administered galanin-like peptide modifies food intake in the rat: a comparison with galanin.

Journal: Journal of neuroendocrinology 20021101

Title: Selective inhibition of Abeta42 production by NSAID R-enantiomers.

Journal: Journal of neurochemistry 20021101

Title: Drug therapy of urinary urge incontinence: a systematic review.

Journal: Obstetrics and gynecology 20021101

Title: A nitric oxide-donating flurbiprofen derivative reduces neuroinflammation without interacting with galantamine in the rat.

Journal: European journal of pharmacology 20021025

Title: Efficient synthesis of alpha-aryl esters by room-temperature palladium-catalyzed coupling of aryl halides with ester enolates.

Journal: Journal of the American Chemical Society 20021023

Title: Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs.

Journal: The Journal of biological chemistry 20021011

Title: Thermodynamic study of the enantiomeric resolution of flurbiprofen by HPLC using Chiralpak AD-RH column.

Journal: Die Pharmazie 20021001

Title: Biochemical stabilization enhances red blood cell recovery and stability following cryopreservation.

Journal: Cryobiology 20021001

Title: Rapid and simple quantitative assay method for diastereomeric flurbiprofen glucuronides in the incubation mixture.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020825

Title: Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study.

Journal: Life sciences 20020816

Title: Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application.

Journal: Biomaterials 20020801

Title: Prostaglandin synthesis inhibitor affects humoral conditions and oxygen metabolism during normothermic cardiopulmonary bypass.

Journal: Artificial organs 20020801

Title: Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration.

Journal: Diabetes 20020801

Title: [The effectiveness of perioperative intravenous flurbiprofen in minor ear, neck and nose surgery].

Journal: Masui. The Japanese journal of anesthesiology 20020801

Title: In vitro release studies of flurbiprofen from different topical formulations.

Journal: Drug development and industrial pharmacy 20020801

Title: The cannabinoids R(-)-7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl (HU-210), 2-O-arachidonoylglycerylether (HU-310) and arachidonyl-2-chloroethylamide (ACEA) increase isoflurane provoked sleep duration by activation of cannabinoids 1 (CB1)-receptors in mice.

Journal: Neuroscience letters 20020705

Title: Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones.

Journal: Bone 20020701

Title: Flurbiprofen does not change the bispectral index and 95% spectral edge frequency during total intravenous anaesthesia with propofol and fentanyl.

Journal: European journal of anaesthesiology 20020701

Title: Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: mediation by salicylic acid.

Journal: Digestive diseases and sciences 20020701

Title: Peripheral analgesic sites of action of anti-inflammatory drugs.

Journal: International journal of clinical practice. Supplement 20020701

Title: Catalytic properties of rice alpha-oxygenase. A comparison with mammalian prostaglandin H synthases.

Journal: The Journal of biological chemistry 20020621

Title: ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater.

Journal: Pain 20020601

Title: In vivo activation of N-methyl-D-aspartate receptors in the rat hippocampus increases prostaglandin E(2) extracellular levels and triggers lipid peroxidation through cyclooxygenase-mediated mechanisms.

Journal: Journal of neurochemistry 20020601

Title: Lipids and nitric oxide in porcine retinal and choroidal blood vessels.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020601

Title: Flurbiprofen release from Eudragit RS and RL aqueous nanosuspensions: a kinetic study by DSC and dialysis experiments.

Journal: AAPS PharmSciTech 20020601

Title: Preparation of solid dispersions of nonsteroidal anti-inflammatory drugs with acrylic polymers and studies on mechanisms of drug-polymer interactions.

Journal: AAPS PharmSciTech 20020601

Title: Demonstration of dose response of flurbiprofen lozenges with the sore throat pain model.

Journal: Clinical pharmacology and therapeutics 20020501

Title: Nitric oxide-releasing drugs: a novel class of effective and safe therapeutic agents.

Journal: Annals of the New York Academy of Sciences 20020501

Title: Affinity capillary electrophoresis using a low-concentration additive with the consideration of relative mobilities.

Journal: Analytical chemistry 20020415

Title: Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: effect on atypical kinetic metabolism profiles.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020401

Title: [A simple method for determination of flurbiprofen in human plasma by gas chromatography-mass spectrometry].

Journal: Masui. The Japanese journal of anesthesiology 20020401

Title: Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020315

Title: Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives.

Journal: Electrophoresis 20020301

Title: Multidose flurbiprofen 8.75 mg lozenges in the treatment of sore throat: a randomised, double-blind, placebo-controlled study in UK general practice centres.

Journal: International journal of clinical practice 20020301

Title: Prediction of poly(ethylene) glycol-drug eutectic compositions using an index based on the van't Hoff equation.

Journal: Pharmaceutical research 20020301

Title: Prediction of selectivity for enantiomeric separations of uncharged compounds by capillary electrophoresis involving dual cyclodextrin systems.

Journal: Journal of chromatography. A 20020301

Title: Beneficial effects of NO-releasing derivative of flurbiprofen (HCT-1026) in rat model of vascular injury and restenosis.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020201

Title: Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).

Journal: Journal of molecular graphics & modelling 20020101

Title: Nitric-oxide releasing molecules: a new class of drugs with several major indications.

Journal: Current pharmaceutical design 20020101

Title: The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma.

Journal: Cancer investigation 20020101

Title: Therapeutic utility of aspirin in the ApcMin/+ murine model of colon carcinogenesis.

Journal: BMC cancer 20020101

Title: Mechanism of in vitro release kinetics of flurbiprofen loaded ethylcellulose micropellets.

Journal: Acta poloniae pharmaceutica 20020101

Title: Prostaglandin synthesis inhibitor prevents hypotension without impairing gut perfusion during normothermic cardiopulmonary bypass.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20020101

Title: Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.

Journal: Digestion 20020101

Title: Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity.

Journal: Neurobiology of aging 20020101

Title: Separation and determination of diastereomeric flurbiprofen acyl glucuronides in human urine by LC/ESI-MS with a simple column-switching technique.

Journal: Drug metabolism and pharmacokinetics 20020101

Title: Elimination profiles of flurbiprofen and its metabolites in equine urine for doping analysis.

Journal: Talanta 20011224

Title: Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011201

Title: Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.

Journal: Journal of neuroscience research 20011115

Title: Validation of subcutaneous microdialysis sampling for pharmacokinetic studies of flurbiprofen in the rat.

Journal: Journal of pharmaceutical sciences 20011101

Title: Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.

Journal: Immunopharmacology and immunotoxicology 20011101

Title: Interactive roles of superoxide and inducible nitric oxide synthase in rat intestinal injury provoked by non-steroidal anti-inflammatory drugs.

Journal: European journal of pharmacology 20011019

Title: Inhibition of human brain tumor cell growth by the anti-inflammatory drug, flurbiprofen.

Journal: Oncogene 20011018

Title: Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015

Title: Dominant role of an endothelium-derived hyperpolarizing factor (EDHF)-like vasodilator in the ciliary vascular bed of the bovine isolated perfused eye.

Journal: British journal of pharmacology 20011001

Title: Cyclooxygenase-independent actions of cyclooxygenase inhibitors.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001

Title: Measurement of ketoprofen in horse urine using gas chromatography-mass spectrometry.

Journal: Journal of veterinary pharmacology and therapeutics 20011001

Title: The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis.

Journal: Acta orthopaedica Scandinavica 20011001

Title: Nicotine-induced contraction in the rat coronary artery: possible involvement of the endothelium, reactive oxygen species and COX-1 metabolites.

Journal: Journal of cardiovascular pharmacology 20011001

Title: Effect of flurbiprofen on hind-limb suspension-induced bone loss.

Journal: Aviation, space, and environmental medicine 20010901

Title: Comparative evaluation of corneal epithelial permeability after the use of diclofenac 0.1% and flurbiprofen 0.03% after phacoemulsification.

Journal: Journal of cataract and refractive surgery 20010901

Title: Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026).

Journal: Arthritis and rheumatism 20010901

Title: Synthesis and receptor docking studies of N-substituted indole-2-carboxylic acid esters as a search for COX-2 selective enzyme inhibitors.

Journal: European journal of medicinal chemistry 20010901

Title: Palladium-catalyzed alpha-arylation of esters.

Journal: Journal of the American Chemical Society 20010822

Title: Minimal in vivo activation of CYP2C9-mediated flurbiprofen metabolism by dapsone.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010801

Title: Vasorelaxant effect of nitric oxide releasing steroidal and nonsteroidal anti-inflammatory drugs.

Journal: British journal of pharmacology 20010801

Title: Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010701

Title: Bradykinin-induced nociceptor sensitization to heat is mediated by cyclooxygenase products in isolated rat skin.

Journal: The European journal of neuroscience 20010701

Title: Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX.

Journal: The Journal of biological chemistry 20010608

Title: NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain.

Journal: Japanese journal of pharmacology 20010601

Title: Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations.

Journal: Biochemistry 20010501

Title: Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase.

Journal: Biomedical chromatography : BMC 20010501

Title: Proapoptotic anti-inflammatory drugs.

Journal: Urology 20010401

Title: Early clinical trials of chemopreventive and biologic agents: Designs, populations, and endpoints.

Journal: Urology 20010401

Title: Review: uveitis and immunosuppressive drugs.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010401

Title: [Convulsion following the combination of single preoperative oral administration of enoxacine and single postoperative intravenous administration of flurbiprofen axetil].

Journal: Masui. The Japanese journal of anesthesiology 20010401

Title: Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.

Journal: European journal of clinical pharmacology 20010401

Title: Modulation of prostaglandin H synthase activity by conjugated linoleic acid (CLA) and specific CLA isomers.

Journal: Lipids 20010401

Title: Selective inhibition of interleukin-4 gene expression in human T cells by aspirin.

Journal: Blood 20010315

Title: Interactions of inflammatory mediators stimulating release of calcitonin gene-related peptide, substance P and prostaglandin E(2) from isolated rat skin.

Journal: Neuropharmacology 20010301

Title: Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301

Title: Perioperative intravenous flurbiprofen reduces postoperative pain after abdominal hysterectomy.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20010301

Title: Urethane anaesthesia could partly mask antinociceptive effects of non-steroidal anti-inflammatory drugs: a spinal c-Fos protein study.

Journal: Brain research 20010209

Title: Flurbiprofen enantiomers inhibit inducible nitric oxide synthase expression in RAW 264.7 macrophages.

Journal: Pharmaceutical research 20010201

Title: Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

Title: Aortic hyporeactivity to norepinephrine induced by lipopolysaccharide in cirrhotic rats: beneficial effects of a non-steroidal anti-inflammatory drug coupled with a nitric oxide donor.

Journal: Journal of gastroenterology and hepatology 20010101

Title: Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations.

Journal: BMC clinical pharmacology 20010101

Title: Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg.

Journal: BMC medical research methodology 20010101

Title: Directed control of electroosmotic flow in nonaqueous electrolytes using poly(ethylene glycol) coated capillaries.

Journal: Electrophoresis 20010101

Title: Screening procedure for detection of non-steroidal anti-inflammatory drugs and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass spectrometry after extractive methylation.

Journal: Journal of analytical toxicology 20010101

Title: Protection by aspirin of indomethacin-induced small intestinal damage in rats: mediation by salicylic acid.

Journal: Journal of physiology, Paris 20010101

Title: Intracrevicular application of 0.3% Flurbiprofen gel and 0.3% Triclosan gel as anti inflammatory agent. A comparative clinical study.

Journal: Indian journal of dental research : official publication of Indian Society for Dental Research 20010101

Title: Prostaglandin synthesis inhibitor improves hypotension during normothermic cardiopulmonary bypass.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20010101

Title: Effects of epidural fentanyl and intravenous flurbiprofen for visceral pain during cesarean section under spinal anesthesia.

Journal: Journal of anesthesia 20010101

Title: Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cells.

Journal: American journal of respiratory and critical care medicine 20001201

Title: Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs.

Journal: Biochemical and biophysical research communications 20001130

Title: Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells.

Journal: Cancer research 20001015

Title: Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons.

Journal: European journal of pharmacology 20000818

Title: Prostaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells.

Journal: British journal of cancer 20000601

Title: R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production.

Journal: European cytokine network 20000601

Title: Treatment and survival study in the C57BL/6J-APC(Min)/+(Min) mouse with R-flurbiprofen.

Journal: Life sciences 20000114

Title: Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells.

Journal: European journal of pharmacology 19991103

Title: Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19990622

Title: Arachidonic acid and PGE2 regulation of hepatic lipogenic gene expression.

Journal: Journal of lipid research 19990601

Title: Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19990215

Title: Structure-based design of COX-2 selectivity into flurbiprofen.

Journal: Bioorganic & medicinal chemistry letters 19990208

Title: Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid.

Journal: Journal of clinical pharmacology 19981201

Title: Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes.

Journal: Biochemical pharmacology 19980715

Title: Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.

Journal: American journal of veterinary research 19980401

Title: R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer.

Journal: Cancer research 19971001

Title: Differential effects of nonsteroidal anti-inflammatory drugs on constitutive and inducible prostaglandin G/H synthase in cultured bone cells.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19970801

Title: Portal venous transfusion up-regulates Kupffer cell cyclooxygenase activity: a mechanism of immunosuppression in organ transplantation.

Journal: Transplantation 19970715

Title: Membranous nephropathy associated with the use of flurbiprofen.

Journal: Clinical nephrology 19970401

Title: Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.

Journal: Journal of pharmacokinetics and biopharmaceutics 19970201

Title: Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells.

Journal: British journal of cancer 19970101

Title: Up-regulation of cyclooxygenase-2 by product-prostaglandin E2.

Journal: Advances in experimental medicine and biology 19970101

Title: Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 19961201

Title: New insights into the site and mode of antinociceptive action of flurbiprofen enantiomers.

Journal: Journal of clinical pharmacology 19960601

Title: Mediation by prostaglandins of the nitric oxide-induced neurogenic vasodilatation in rat skin.

Journal: British journal of pharmacology 19951101

Title: Protective effect of NO on gastric lesions and inhibition of expression of gastric inducible NOS by flurbiprofen and its nitro-derivative, nitroflurbiprofen.

Journal: British journal of pharmacology 19950901

Title: Flurbinitroxybutylester: a novel anti-inflammatory drug has enhanced antithrombotic activity.

Journal: Thrombosis research 19950701

Title: Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19950501

Title: Aspirin-like drugs can protect human T lymphocytes against benzoquinone cytotoxicity: evidence for a NAD(P)H:quinone reductase-dependent mechanism.

Journal: Archives of toxicology 19950101

Title: A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.

Journal: Molecular pharmacology 19940101

Title: [Cholestasis caused by hypersensitivity to flurbiprofen].

Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 19920801

Title: Renal papillary necrosis induced by flurbiprofen.

Journal: DICP : the annals of pharmacotherapy 19910101

Title: Flurbiprofen-associated acute tubulointerstitial nephritis.

Journal: American journal of nephrology 19910101

Title: Flurbiprofen and cutaneous vasculitis.

Journal: Annals of internal medicine 19900401

Title: Acute parkinsonism associated with flurbibrofen.

Journal: BMJ (Clinical research ed.) 19900224

Title: Simple procedure for measuring the pharmacodynamics and analgesic potential of lipoxygenase inhibitors.

Journal: Journal of pharmacological methods 19881201

Title: Pain suppression after pulpectomy with preoperative flurbiprofen.

Journal: Journal of endodontics 19870701

Title: A case of acute interstitial nephritis induced by flurbiprofen.

Journal: Japanese journal of medicine 19870501

Title: [Acute renal insufficiency caused by observed a combination of enalapril, furosemide and flurbiprofen in a patient with retroperitoneal fibrosis].

Journal: Annales d'urologie 19870101

Title: Flurbiprofen in the treatment of juvenile rheumatoid arthritis.

Journal: The Journal of rheumatology 19861201

Title: Flurbiprofen, aspirin, codeine, and placebo for postpartum uterine pain.

Journal: The American journal of medicine 19860324

Title: A long-term study of flurbiprofen in rheumatological disorders: I. Rheumatoid arthritis.

Journal: The Journal of international medical research 19860101

Title: The effect of phenytoin, phenobarbitone, dexamethasone and flurbiprofen on misonidazole neurotoxicity in mice.

Journal: British journal of cancer 19840201

Title: A non-steroidal anti-inflammatory drug (flurbiprofen) to control idiopathic hypercalciuria resistant to dietary manipulation.

Journal: British journal of urology 19831201

Title: Side effects of non-steroidal anti-inflammatory drugs.

Journal: British medical journal (Clinical research ed.) 19820731

Title: Double-bind cross-over tiral of flurbiprofen and phenylbutazone in ankylosing spondylitis.

Journal: British medical journal 19741130

Title: Double-blind cross-over comparison of indomethacin, flurbiprofen, and placebo in ankylosing spondylitis.

Journal: Annals of the rheumatic diseases 19740301