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516-85-8,MFCD00083319
Catalog No.:AA00DHNC

516-85-8 | DEHYDROERGOSTEROL

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1mg
≥98%
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$48.00   $33.00
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5mg
≥98%
in stock  
$138.00   $96.00
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10mg
≥98%
in stock  
$252.00   $176.00
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25mg
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$566.00   $396.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DHNC
Chemical Name:
DEHYDROERGOSTEROL
CAS Number:
516-85-8
Molecular Formula:
C28H42O
Molecular Weight:
394.6325
MDL Number:
MFCD00083319
SMILES:
O[C@H]1CC[C@]2(C(=CC=C3C2=CC[C@]2([C@H]3CC[C@@H]2[C@@H](/C=C/[C@@H](C(C)C)C)C)C)C1)C
Properties
Properties
 
Form:
Solid  
MP:
133 - 138°C  
Storage:
Light sensitive;-20 ℃;Inert atmosphere;  

Computed Properties
 
Complexity:
765  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
6.9  

Literature

Title: Analysis of cholesterol trafficking with fluorescent probes.

Journal: Methods in cell biology 20120101

Title: Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM.

Journal: Traffic (Copenhagen, Denmark) 20111001

Title: Sterol transfer between cyclodextrin and membranes: similar but not identical mechanism to NPC2-mediated cholesterol transfer.

Journal: Biochemistry 20110830

Title: Labeling membranes with fluorescent cholesterols.

Journal: Cold Spring Harbor protocols 20110501

Title: Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol.

Journal: Chemistry and physics of lipids 20110301

Title: The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: dehydroergosterol fluorescence study.

Journal: Biochemical and biophysical research communications 20110107

Title: Potential of ultraviolet wide-field imaging and multiphoton microscopy for analysis of dehydroergosterol in cellular membranes.

Journal: Microscopy research and technique 20110101

Title: Comparison of three ternary lipid bilayer mixtures: FRET and ESR reveal nanodomains.

Journal: Biophysical journal 20101117

Title: Selective visualization of fluorescent sterols in Caenorhabditis elegans by bleach-rate-based image segmentation.

Journal: Traffic (Copenhagen, Denmark) 20100401

Title: The fluorescent cholesterol analog dehydroergosterol induces liquid-ordered domains in model membranes.

Journal: Chemistry and physics of lipids 20090601

Title: Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers.

Journal: Biophysical journal 20090520

Title: Fluorescence techniques using dehydroergosterol to study cholesterol trafficking.

Journal: Lipids 20081201

Title: Structure of dehydroergosterol monohydrate and interaction with sterol carrier protein-2.

Journal: Lipids 20081201

Title: Sterol superlattice affects antioxidant potency and can be used to assess adverse effects of antioxidants.

Journal: Analytical biochemistry 20081101

Title: Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells.

Journal: Histochemistry and cell biology 20081101

Title: Regulation of sterol transport between membranes and NPC2.

Journal: Biochemistry 20081021

Title: Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells.

Journal: Journal of lipid research 20080901

Title: Free-cholesterol loading does not trigger phase separation of the fluorescent sterol dehydroergosterol in the plasma membrane of macrophages.

Journal: Chemistry and physics of lipids 20080801

Title: Chromatic aberration correction and deconvolution for UV sensitive imaging of fluorescent sterols in cytoplasmic lipid droplets.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080801

Title: Lipid droplet changes in proliferating and quiescent 3T3 fibroblasts.

Journal: Histochemistry and cell biology 20080501

Title: Kinetics and thermodynamics of the association of dehydroergosterol with lipid bilayer membranes.

Journal: Biophysical journal 20071215

Title: Fluorescent sterols as tools in membrane biophysics and cell biology.

Journal: Chemistry and physics of lipids 20070301

Title: Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect.

Journal: Traffic (Copenhagen, Denmark) 20070201

Title: Fluorometric assay for detection of sterol oxidation in liposomal membranes.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: Multiphoton laser-scanning microscopy and spatial analysis of dehydroergosterol distributions on plasma membrane of living cells.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: Structure and cholesterol dynamics of caveolae/raft and nonraft plasma membrane domains.

Journal: Biochemistry 20061003

Title: Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation.

Journal: Free radical biology & medicine 20060615

Title: Sterol binding assay using surface plasmon fluorescence spectroscopy.

Journal: Analytical chemistry 20060115

Title: Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice.

Journal: Neuromolecular medicine 20060101

Title: Improved visualization and quantitative analysis of fluorescent membrane sterol in polarized hepatic cells.

Journal: Journal of microscopy 20051001

Title: Combined interaction of phospholipase C and apolipoprotein A-I with small unilamellar lecithin-cholesterol vesicles: influence of apolipoprotein A-I concentration and vesicle composition.

Journal: Biochemistry 20050517

Title: Construction of cryptogein mutants, a proteinaceous elicitor from Phytophthora, with altered abilities to induce a defense reaction in tobacco cells.

Journal: Biochemistry 20050503

Title: Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells.

Journal: Traffic (Copenhagen, Denmark) 20050501

Title: Structural analysis of sterol distributions in the plasma membrane of living cells.

Journal: Biochemistry 20050301

Title: Role of sterol superlattice in free radical-induced sterol oxidation in lipid membranes.

Journal: Biochemistry 20050215

Title: Binding mechanism of nonspecific lipid transfer proteins and their role in plant defense.

Journal: Biochemistry 20041102

Title: Structure and cholesterol domain dynamics of an enriched caveolae/raft isolate.

Journal: The Biochemical journal 20040901

Title: Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes.

Journal: The Journal of biological chemistry 20040402

Title: Cholesterol superlattice modulates the activity of cholesterol oxidase in lipid membranes.

Journal: Biochemistry 20040302

Title: Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells.

Journal: Journal of lipid research 20040301

Title: Cholesterol crystal nucleation from enzymatically modified low-density lipoproteins: combined effect of sphingomyelinase and cholesterol esterase.

Journal: Biochemistry 20040217

Title: Relationship between sterol/steroid structure and participation in ordered lipid domains (lipid rafts): implications for lipid raft structure and function.

Journal: Biochemistry 20040203

Title: Interaction of apolipoprotein A-I with lecithin-cholesterol vesicles in the presence of phospholipase C.

Journal: Biochimica et biophysica acta 20031230

Title: Sterol carrier protein-2 selectively alters lipid composition and cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell fibroblast plasma membranes.

Journal: Biochemistry 20031216

Title: Fluorescence and multiphoton imaging resolve unique structural forms of sterol in membranes of living cells.

Journal: The Journal of biological chemistry 20030221

Title: Role of the sterol carrier protein-2 N-terminal membrane binding domain in sterol transfer.

Journal: Biochemistry 20021008

Title: Rapid transbilayer movement of the fluorescent sterol dehydroergosterol in lipid membranes.

Journal: Biophysical journal 20020901

Title: The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands.

Journal: The Journal of biological chemistry 20020628

Title: Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle.

Journal: The Journal of biological chemistry 20020104

Title: Cholesterol organization in membranes at low concentrations: effects of curvature stress and membrane thickness.

Journal: Biophysical journal 20011001

Title: Characterization of model bile using fluorescence energy transfer from dehydroergosterol to dansylated lecithin.

Journal: Journal of lipid research 20010601

Title: A photophysical study of the polyene antibiotic filipin. Self-aggregation and filipin--ergosterol interaction.

Journal: Biochimica et biophysica acta 20010209

Title: Fatty acids bind to the fungal elicitor cryptogein and compete with sterols.

Journal: FEBS letters 20010126

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Tags:516-85-8 Molecular Formula|516-85-8 MDL|516-85-8 SMILES|516-85-8 DEHYDROERGOSTEROL